Exam 9 - Short Term Control Of BP Flashcards
(44 cards)
Local flow to tissues
- Depends on constant pressure drop across tissues
- MAP - CVP = constant
Arterial compliance
2 mls/mmHg
Venous compliance
100 mls/mmHg
Hormonal mechanisms for controlling BP
- Aldosterone
- Renin-angiotensin-vasoconstriction
Nervous mechanisms for BP control
- Baroreceptors (moment to moment / normal changes)
- Chemoreceptors
- CNS ischemic response
Physiologic mechanisms for BP control
- Capillary fluid shift (normal to abnormal changes)
- Stress relaxation of vasculature (normal to abnormal changes)
Renal mechanism for BP control
- Renal-blood volume pressure control
- long term control….everything else short term
Filtration/absorption rate
- If MAP increase….filtration increase
- If MAP decrease….absorption increase
4 quickest activated mechanisms
- Within seconds
- Baroreceptors
- Chemoreceptors
- CNS ischemic response
- Stress relaxation
2 average reaction time mechanisms
- Within minutes
- Renin-angiotensin-vasoconstriction
- Capillary fluid shift
2 slowest reacting mechanisms
- Within hours
- Aldosterone
- Renal-blood volume pressure control
5 average strength mechanisms
- Max feedback of 4% increase relative
- Bring BP back CLOSE to normal
- Chemoreceptors
- Stress relaxation
- Renin-angiotensin-vasoconstriction
- Capillary fluid shift
- Aldosterone
2 strong mechanisms
- Max feedback of 7 & 11
- Bring BP back CLOSE to normal
- Baroreceptors
- CNS ischemic response
1 infinite strength response
- Renal-blood volume pressure control
- Can bring BP back to NORMAL
Which mechanisms play role on bypass
- All except Aldosterone and Renal-blood volume pressure
- CPB not on long enough to activate those two
- Average case only 90 minutes
- These two take 4 hours to activate
Which change in BP to these mechanisms respond to
- Mostly drops in BP
- Except Baroreceptors…they do both
Innervation of the heart
- Sympathetic and Parasympathetic
Innervation of arterioles
- Sympathetic
Parasympathetic control
- Regulates HR
- Small/No affect on contractility
- only atrial filling - Minimal regulation of circulation
Sympathetic control
- Regulate contractility
- Regulates circulation
Vasomotor center pathways
- Efferent pathways
- Parasympathetic impulses via vagus nerve
- Sympathetic impulses via spinal cord and peripheral sympathetic nerves to arteries, arterioles, and veins
Sympathetic nerve fibers
- Exit spinal cord via thoracic spinal nerves and first 2 lumbar
- Enter sympathetic chains either side of spinal cord
- To circulation 2 ways:
- specific nerves directly to heart and internal viscera
- peripheral portions of spinal nerves to peripheral vasculature
Which vessels innervated by sympathetic
- Arteries / Arterioles - change resistance and flow to tissue
- Veins / Venuoles - change volume held…changing return
- SOME metarterioles and pre-cap sphincters of mesenteric
- most are not - Most are vasoconstrictors: kidney/ intestines/ spleen/ skin
- weak vasoconstriction in skeletal muscle / brain - When impulses sent to vessels…also sent to adrenal medulla
- releases Epi and NE
Vasomotor center location
- Bilateral
- all efferent neurons come out of here
- In medulla and lower third of pons
- regulates amount of vascular constriction AND cardiac activity
- like HR and contractility