EXAM I Review T/F Part2

Question 1

LPS is a pyrogen

Answer 1

True

Question 2

LPS is a endotoxin

Answer 2

True

Question 3

LPS is a exotoxin

Answer 3

False

Question 4

LPS is a toll-like receptor ligand

Answer 4

True

Question 5

LPS is a common molecule is a gram-positive bacteria

Answer 5

False

Question 6

A toxoid is a particularly potent toxin

Answer 6

False

Question 7

Diapedesis is the same as extravasion

Answer 7

True

Question 8

“LAD” stands for “Lateral Asymmetric Disjunction”

Answer 8

False

Question 9

“PAMP” stands for “Pathogen Associated Molecular Pattern”

Answer 9

True

Question 10

“PRR” stands for “Pathogen Recognition Receptor”

Answer 10

True

Question 11

“TLR” stand for “Toll-like receptor”

Answer 11

True

Question 12

TLRs are important PRRS

Answer 12

True

Question 13

TLR ligands include LPS, flagellin, and unmethylated CpG DNA

Answer 13

True

Question 14

TLR ligands include methylated CpG DNA, ds RNA, and Hsp60

Answer 14

False

Question 15

Some TLRs detect endosomal ligands

Answer 15

True

Question 16

TLRs only detect extracellular ligands

Answer 16

False

Question 17

TLRs never hetrodimerize

Answer 17

False

Question 18

TLRs never homodimerize

Answer 18

False

Question 19

Adjuvant comes from the Latin word meaning “to share”

Answer 19

False

Question 20

Freund’s complete adjuvant contains oil

Answer 20

True

Question 21

Freund’s complete adjuvant contains killed Mycobacteria

Answer 21

True

Question 22

Freund’s complete adjuvant contains alum

Answer 22

False

Question 23

Freund’s complete adjuvant is used in many human vaccines

Answer 23

False

Question 24

Precipitated or aggregated antigen is not immunogenic

Answer 24

False

Question 25

Presence of TLR ligands makes immune responses weaker

Answer 25

False

Question 26

Intravenous administration of antigen is maximally immunogenic

Answer 26

False

Question 27

Oral administration of antigen can lead to tolerance

Answer 27

True

Question 28

DNA is a good immunogen

Answer 28

False

Question 29

Small Compounds such as caffeine are excellent immunogens

Answer 29

False

Question 30

Polylysine is an excellent immunogen

Answer 30

False