Exam III

Question 1

Procainamide

a. Loading
b. Infusion

Answer 1

a. 100mg q5 min until rate controlled

b. 2-6 mg/min

Question 2

Lidocaine

a. Loading
b. Infusion

Answer 2

a. 2 mg/kg

b. 1-4 mg/min

Question 3

Phenytoin

a. IV
b. Max

Answer 3

a. 100 mg q5min

b. Max 1,000 mg

Question 4

Propranolol

a. IV

Answer 4

1 mg/min (Max 3-6 mg)

Question 5

Metoprolol

Answer 5

5mg over 5 min (Max 15mg over 20 min)

Question 6

Esmolol

a. Loading
b. Drip

Answer 6

a. 0.5mg/kg over 1 min

b. 50-300 mcg/kg/min

Question 7

Amiodarone

a. Bolus
b. 6hr rate
c. 18 hr rate

Answer 7

a. 150-300 mg over 2-5 min
b. 1 mg/min over 6 hrs
c. 0.5 mg/min over 18 hrs

Question 8

Verapamil.

a. Loading
b. Drip

Answer 8

a. 2.5-10mg over 1-3 minutes

b. 5 µg/kg/min

Question 9

Diltiazem

a. Loading
b. Continuous
c. SVT

Answer 9

a. 5-20mg over 2 min
b. 10 mg/hr
c. 0.25 mg/kg

Question 10

Amrinone

a. Loading
b. Infusion

Answer 10

a. 1 mg/kg over 5 min

b. 2-10 µg/kg/min

Question 11

Milrinone

a. Loading
b. Infusion

Answer 11

a. 50 µg/kg

b. 0.5 µg/kg/min

Question 12

Albuterol

a. MDI

Answer 12

a. 2 puffs q 4-6 hours (100 µg/puff)

Question 13

Terbutaline

a. Adult MDI/SQ
b. Pediatric SQ

Answer 13

a. 250 µg puff

b. 10 µg/kg

Question 14

Glycoprotein IIb/IIIa activated by:

Answer 14

1. Thromboxane A2
2. Thrombin
3. Collagen
4. Platelet activation factor
5. ADP

Question 15

TXA

a. Loading
b. Drip

Answer 15

a. 1gm in 100cc over 10 minutes

b. 1gm in 100cc over 8 hours

Question 16

Lispro Insulin (Rapid):

a. Onset
b. Peak
c. DOA

Answer 16

a. 10-15 min
b. 30-60 min
c. 3-5 hours

Question 17

Regular Insulin (Short Acting)

a. Onset
b. Peak
c. DOA

Answer 17

a. 30-60 min
b. 1-5 hours
c. 5-10 hours

Question 18

NPH Insulin (Intermediate):

a. Onset
b. Peak
c. DOA

Answer 18

a. 1-2 hours
b. 6-10 hours
c. 16-20 hours

Question 19

Lantus Insulin (Long Acting)

a. Onset
b. Peak
c. DOA

Answer 19

a. 2-6 hours
b. None
c. 24 hours

Question 20

1 Unit Insulin BG Effects:

a. Type I DM
b. Type II DM

Answer 20

a. ↓ BS by 40-50 mg/dl

b. ↓ BS by 30-40 mg/dl

Question 21

Sulfonylureas

Answer 21

Close ATP sensitive K+ channels; INCREASE INSULIN RELEASE from Beta cells; have LONG DOA

Question 22

Biguanides

Answer 22

Decrease hepatic/renal glucose production; no CRF patients; can cause lactic acidosis

Question 23

Thiazolidinediones

Answer 23

Improves insulin sensitivity/decreases resistance in muscle and adipose tissue; can exacerbate CHF d/t edema

Question 24

Alpha-glucosidase Inhibitors

Answer 24

Antagonize enzymes in the intestinal brush border for digesting complex carbs; can cause GI issues

Question 25

Meglitinides

Answer 25

Close ATP sensitive K+ channels; INCREASE INSULIN RELEASE from Beta cells; have SHORT DOA

Question 26

Gliptins

Answer 26

INCREASE INSULIN RELEASE; can cause pancreatitis, delayed gastric emptying (aspiration), have long DOA

Question 27

Endogenous Daily Cortisol Release

Answer 27

10-20 mg on average; 50-100 mg during stress

Question 28

Cortisol (Cortisone) a. Gluco/Mineral ratio b. DOA

Answer 28

a. 1:1 (0.8:0.8) | b. 8-12 hours (8-36 hours)

Question 29

Dexamethasone (Betamethasone) a. Gluco/Mineral ratio b. DOA

Answer 29

a. 25:0 (Same) | b. 36-54 hours (Same)

Question 30

Prednisone (Methylprednisolone) a. Gluco/Mineral ratio b. DOA

Answer 30

a. 4/0.8 (5:0.5) | b. 18-36 hours (12-36 hours)

Question 31

Glucagon a. IV Push b. Drip

Answer 31

a. 1-5 mg | b. 5 µg/kg/min

Question 32

Octreotide a. Carcinoid Crisis b. Esophageal Varicies

Answer 32

a. 50-100 µg/hr (PRN bolus of 25-100µg) | b. 50 µg/hr

Question 33

Oxytocin | a. Uterine Atony

Answer 33

a. 40 mU/min