Exam2 Qbank Flashcards

All (87 cards)

1
Q

CN III compression

A

Ptosis
Mydriasis
Down ^ out
Paralysis of accommodation (cycloplegia)

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2
Q

MAO inhibitors

MAO Takes Pride In Shanghai

A

Tranylcypromine
Phenelzine
Isocarboxazid
Selegiline (selective MAO-B inhibitor)

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3
Q

Sclerosing cholangitis is assoc w/

A

Ulcerative colitis = bloody diarrhea ^ inflammatory “pseudopolyps”

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4
Q

Stroke volume = ?

A

LVEDV - LVESV

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5
Q

Aortic stenosis leads to

A

⬆️LVEDV
⬆️LVESV
⬆️peak systolic pressure

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6
Q

Doxorubicin

Which drug prevent cardiotoxicity ?

A

Anthracycline ATB

Dexrazoxane: derivative of EDTA

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7
Q

Cisplatin

A

Amifostine: ⬇️renal toxicity

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8
Q

Methotrexate

A

Leucovorin diminish toxicity

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9
Q

Cyclophosphamide ^ ifosfamide

A

Mesna reduce incidence of hemorrhagic cystitis

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10
Q

Cholera toxin interacts w/ ?

A

G protein

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11
Q

Ewing sarcoma

A

S-100

Homer-wright pseudorosettes

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12
Q

Nerve that courses around the medial malleolus

A

Posterior tibial nerve

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13
Q

Blood supply of the pancreas

A

Body ^ tail: splenic artery SPLENIC ARTERY

Head: inf pancreaticoduodenal artery SMA

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14
Q

Specialized transduction

A

All of the progeny phage would be identical and able to transduce

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15
Q

Drug that blunt postprandial increase in plasma glucose

A

Acarbose

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16
Q

Lesion that damages the common peroneal nerve

A

A lesion near the neck of the fibula

Superficial: eversion, dorsum
Deep: dorsiflexion

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17
Q

44yo rapid onset of hematuria, HTN ^ renal failure

A

RPGN: proliferation of cells in the urinary space of most of the glomeruli

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18
Q

Glucokinase

A

Hepatocytes and pancreas

Glucose phosphorylation, trapping ^ insulin release

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19
Q

Epidural hematoma

A

Regain consciousness and have a Lucid period that lasts several hours

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20
Q

Drugs w/ alfa blocking activity

A

Antipsychotics: chlorpromazine

TCA

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21
Q

Withdrawal sx that causes life threatening symptoms ?

A

Barbiturates

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22
Q

SIADH

A

⬇️plasma osmolarity

⬇️plasma sodium

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23
Q

Alexia w/o agraphia

Left PCA

A

Lef occip cortex

Splenium of the corpus callosum

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24
Q

Intestinal granulomatous diseases (2)

A
Crohn disease (acid fast -)
Intestinal tuberculosis (acid fast +)
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25
MCH I associated protein ?
B2-microglobulin
26
MCH II | associated protein ?
Invariant chain
27
Most important predictor of early and late stage HIV infection
Early: viral load Late: CD4 count
28
Churg-Strauss syndrome | P-ANCA
Granulomas ^ vasculitis: lung, skin, peripheral nerves | Bronchial asthma, eosinophilia
29
bcl-2 overexpression
B cell lymphomas : follicular ^ undifferentiated | 18 chrom
30
Aminoacids negatively charged at body pH? (2)
Aspartate | Glutamate
31
Which cell type develop sensitization to lepromin test ?
TH1 cell
32
Lead poisoning | Antidote ?
Succimer
33
Unilateral deafness
Cochlear nucleus deafness
34
Weber test | Vibrating tuning 🍽 in the middle of the head
Conductive: louder in the affected ear Sensorineural: louder in the unaffected ear
35
Weber test | Vibrating tuning 🍽 in the middle of the head
Conductive: louder in the affected ear Sensorineural: louder in the unaffected ear
36
Schüffner's dots P vivax ^ ovale Drug against hypnozoites ?
Primaquine
37
Paget disease result from underlying?
DCIS
38
Drug to treat pregnant women w/gonorrhea who cannot tolerate a cephalosporin atb ^ children < 45 kg w/ uncomplicated gonococcal infections
Spectinomycin
39
Oxybutynin
Muscarinic antagonist. Used to treat incontinence
40
Glycogen molecules w/short outer branches
Cori disease | Debranching enzyme
41
Long Chain acyl CoA dehydrogenase LCAD
Muscle weakness and cardiomiopathy | Fasting hypoglycemia ^ hypoketosis
42
Hypoventilation
Does not produce A-a Po2 difference | ⬆️A-a Pco2
43
HUS
Occurs in children after infections w/E. Coli Mild hemolytic anemia Glomerular thrombosis ^ collapse
44
Marantic endocarditis
Sterile vegetations Fibrin precipitations Along the line of closure of the mitral valve
45
Chest trauma (2)
Cardiac contusion | Cardiac tamponade
46
CCK functions ? (2)
Gallbladder contraction | Sphincter of Oddi relaxation
47
Adrenocorical insufficiency
Weakness Weight loss Skin pigmentation
48
Broad based budding yeast found in rotten wood
Blastomyces dermatitidis
49
Initial therapy for septic shock?
Dopamine | Alfa 1 ^ beta 1
50
Which drug causes livedo reticularis (purplish red mottling)
Amantadine: local release of NE
51
Warfarin
Inhibit hepatic synthesis of vit K (2,7,9,10,C,S)
52
Scopolamine
Antimuscarinic: tachycardia, constipation, urinary retention, dry mouth
53
Lab test for confirmation of Borrelia burgdorferi infection ?
Western blot for detection of antibodies
54
Shunt that affects arterial o2 content ?
Right to left
55
⬆️AFP
Marked ⬆️: hepatocellular ca, germ cell tumors w/yolk sac component Small ⬆️: GI ^ lung tumors Prenatal neural tube defects
56
Pinworm: enterobius vermicularis | Treatment ?
Mebendazole
57
Patchy infliltrates after lung transplant | Lymphocytes, inflammatory response
ACUTE REJECTION: can occur between 2wks-2yrs
58
Nerve injured during radical mastectomy
Long thoracic nerve: serratus anterior
59
Low Na Low plasma osmolarity Normovolemia
Hypothyroidism SIADH hypoadrenalism Diuretic use
60
Blood volume formula
BV= Plasma volume/(1 - fractional hematocrit) FH=40% ➡️0.4
61
Alfa 1 antitrypsin | Emphysema ?
Panacinar
62
Aorticopulmonary septum
Neural crest cells
63
Axilary nerve innervates ?
Teres minor Deltoid Triceps brachii
64
Cremasteric reflex
L1-L2
65
Digoxin
``` HF(⬆️contractility) Atrial fibrillation (⬇️conduction AV node) ```
66
High levels can be measured within an hour after exercise
VEGF
67
Conotruncal ridges participates in the formation of
The membranous IV septum | Aorticopulmonary septum
68
BB contraindicated in angina
Pindolol: it does not ⬇️ myocardial O2 demand | ISA
69
⬆️DBP
⬆️SVR: alfa 1
70
Refractory Crohn disease
Infliximab | Monoclonal ab against TNF
71
OH withdrawal (4)
Minor tremulousness Anxiety Headache Palpitations
72
Delirium tremens
``` Hallucinations Tachycardia Disorientation HTN Fever Agitation Diaphoresis Grand mal seizures ```
73
ACEI contraindication ?
Renovascular HTN
74
3rd pharyngeal arch
Stylopharyngeus muscle
75
Best evidence that the anemia is due to a primary deficiency of B12 ?
⬆️ methylmalonate
76
Acyclovir | Mechanism of action ?
Inhibit viral DNA polymerase
77
Retroperitoneal organs
Ascending ^ descending colon Duodenum Kidneys
78
Pulmonary vascular resistance | Formula ?
R= (pulm art pressure - pulm venous pressure)/CO
79
Dopamine antagonist
Haloperidol
80
Uncontrolled HTN + BPH | treatment ?
Alfa 1 receptors blockers Prazosin Terazosin Doxazosin
81
Oxygen consumption | Fick equation
Oxygen consumption = CO * (arterial O2 content - venous O2 content)
82
Drugs that inhibit P-450 system ?
Ketoconazole Cimetidine Isoniazid
83
Drugs that induce P-450 system?
Barbiturates CBZ Phenytoin Rifampin
84
Neoplastic diseases caused by virus
``` Adult T-cell leukemia/lymphoma➡️HTLV-1 Burkitt lymphoma➡️EBV Hepatocellular carcinoma➡️HBV cervical ca➡️HPV Kaposi sarcoma➡️HIV ```
85
Inulin | PAH
Inulin: freely filtered, 🚫secreted, 🚫 reabsorbed PAH: freely filtered ^ secreted, 🚫 reabsorbed
86
Competitive inhibitor
⬆️ Km
87
Hemochromatosis
HLA-A3 allele Iron Prussian blue