Excipients

Question 1

EDTA (ethylene diamine tetra acetic acid)

Answer 1

chelator, penetrator

Question 2

magnesium stearate

Answer 2

lubricant (insoluble in H2O)

Question 3

corn starch

Answer 3

binder, disintegrant

Question 4

colloidal silicon dioxide

Answer 4

glider (improves flow), dessicant (absorbs moisture)

Question 5

gelatin

Answer 5

binder (makes capsules and caps shells)

Question 6

talc

Answer 6

lubricant (not as good as mag stearate)

Question 7

sucrose

Answer 7

sweetener, diluent, filler

Question 8

calcium stearate

Answer 8

lubricant (insoluble in H2O)

Question 9

stearic acid

Answer 9

lubricant (more soluble in H2O), emulsifier

Question 10

titanium dioxide

Answer 10

white pigment (insoluble in H2O)

Question 11

HPMC

Answer 11

gelatin alternative for caps, used in controlled release

Question 12

sodium lauryl sulfate

Answer 12

surfactant, lubricant (water-soluble)

Question 13

PVP/Povidone

Answer 13

binder, makes water-soluble matrices

Question 14

croscarmellose sodium

Answer 14

super disintegrant

Question 15

propyl paraben

Answer 15

preservative

Question 16

benzalkonium bromide

Answer 16

preservative (NEVER use in children –> cause death)

Question 17

xanthum gum

Answer 17

binder, thickening agent, alternative for gelatin in emulsions/suspensions

Question 18

sodium saccharin

Answer 18

sweetener

Question 19

sucralose

Answer 19

sweetener

Question 20

sorbitol

Answer 20

plasticizer, sugar-alternative

higher conc –> laxative, osmotic agent

Question 21

ferric oxide

Answer 21

red dye

Question 22

microcrystalline cellulose

Answer 22

tablet diluent (best for direct compression)

Question 23

dicalcium phosphate

Answer 23

tablet filler (insoluble in water, can trap drug particles and slow down drug release)

Question 24

sodium starch glycolate

Answer 24

super disintegrant

Question 25

methyl paraben

Answer 25

preservative

Question 26

sodium benzoate

Answer 26

preservative

Question 27

potassium sorbate

Answer 27

preservative

Question 28

carbomer

Answer 28

gelling agent, suspending agent

Question 29

aspartame

Answer 29

sweetener

Question 30

mannitol

Answer 30

sweetener (highly soluble, can use as alternative to microcrystalline cellulose)

Question 31

Tween 80/ Polysorbate 80

Answer 31

emulsifier, surfactant

Question 32

sodium bicarbonate

Answer 32

alkalizing agent (change pH to be more basic -- esp in stomach)