Exocrine Pancreas Flashcards

1
Q

Functional unit

A

Accinus = acinar cells (for enzymes synthesis, storage, secretion)
Duct system = modifies aqueous secretions

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2
Q

Acinar cells

A

digestive enzymes produced on its endoplasmic reticulum

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3
Q

Proteolytic enzymes

A

Chymotrypsinogen + trypsinogen (n the inactive zymogen form)

In the duodenum:
Trypsinogen → trypsin (activated by entero peptidases)
Chymotrypsinogen → chymotrypsin (activated by trypsin)

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4
Q

Lipase

A

Digests triglycerides to monoglycerides, diglycerides + free fatty acids

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5
Q

Amylase

A

Starch + maltose (disaccharide) to smaller carbs

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6
Q

Vagal innervation to pancreas?

A

= stimulated enzyme secretion

Occurs when see/smell/taste food + stretch receptors

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7
Q

Effect of acidic chyme entering duodenum?

A

Stimulates S cells to release secretin

Secretin causes pancreatic cell to secrete alkaline pancreatic juices

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8
Q

Fatty acids in chyme trigger…

A

…duodenal cells to release cholecystokinin (CCK)
Causes digestive enzyme secretion in pancreas
Stimulates bile secretion via gall bladder contraction

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