Experiment 8 Flashcards

1
Q

What are the characteristics of a nucleophile for a substitution reaction?

A

compound that has a negative charge or increase electron density

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2
Q

What are the characteristics of the leaving group in a substitution reaction?

A

leaving group is any group that is willing to be kicked off and is generally electronegative because needs to be happy with a negative charge

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3
Q

What are characteristics of the electrophile in a substitution reaction?

A

electrophile is positively charged or has low electron density

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4
Q

how do pka values of acids relate to whether or not it is a good leaving group?

A

the smaller the pka value of acids (as in negative values) the better leaving group it creates

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5
Q

what solvent favors SN2 reactions?

A

polar aprotic solvents

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6
Q

what solvent hinders SN2 reactions?

A

polar solvents

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7
Q

what is true of protic solvents properties in SN2 reactions?

A

hinder the SN2 because it surrounds the nucleophile to compete with the electrophile of interest. Protic means it has a H that serves as a source of protons. Then acid-base reaction occurs between the nucleophile and the protic solvent

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8
Q

why is water a good leaving group?

A

water is a good leaving group because it is stable

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