FA 3 Flashcards

(49 cards)

1
Q

epidemiology - Mean

A

Sum of values / total number of values

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2
Q

epidemiology - Median

A

Middle value of a list of data sorted from least to greatest

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3
Q

epidemiology - Mode

A

MC value

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4
Q

Measures of central tendency: Most affected by outliers (extreme values)?

A

mean

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5
Q

Least affected by outliers (extreme values)?

Mean mode or median?

A

mode

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6
Q

Measures of dispersion

A
  1. Standard deviation

2. Standard error of the mean

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7
Q

Standard deviation (SD or σ)

A

How much variability exists from the mean in a set of values

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8
Q

Standard error of a mean (SEM)

A

An estimate of how much variability exists between the sample mean and the true population mean

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9
Q

Standard deviation - standard error of the mean

A

SEM=σ/(n riza)

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10
Q

Normal distribution (proportion


A

68%
95%
99.7%

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11
Q

Nonnormal distributions

A
  1. Bimodal
  2. Positive screw
  3. Negative screw
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12
Q

Positive skew

A

Asymmetry with longer tail on right (peak at left)

Mean>median>mode

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13
Q

Negative skew

A

Asymmetry with longer tail on left (peak on right)

Mean is the smaller

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14
Q

statistical variance - definition and equation?

A

Variance is how far a set of numbers are spread out

variance = (standard deviation) in square

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15
Q

how to decrease SEM (standard error of the mean)

A

increases n

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16
Q

standard deviation vs precision

A

increased precision –> decreased standard deviation

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17
Q

Alternative H1 vs null (H0) hypothesis

A

alternative: Hypothesis of some difference or relationship
null: no difference or relationship

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18
Q

Outcomes of statistical hypothesis testing

A
  1. Correct results
    a. Null b. Alternative
  2. Incorrect results
    a. Type I error (α) Type II error (β)
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19
Q

Outcomes of statistical hypothesis testing - correct results explain

A
  1. Stating that there is an effect or difference when one exists (null hypothesis rejected in favor of alternative hypothesis )
  2. Stating that there is not an effect or difference when none exists (null hypothesis not rejected)
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20
Q

Incorrect result - type I error

A

Stating that there is an effect or difference when none exists (null hypothesis incorrectly rejected in favor of alternative hypothesis)
FP ERROR

21
Q

type I error….α?

A

It is the probability of making a type I error

22
Q

type I error…..p?

A

It is judged against a preset α level of significance (usually 0,05). If p less than 0.05, then there is less than a 5% of chance that the data will show something that is not really there

23
Q

Type II error

A

Stating that there is not an effect or difference when one exists (null hypothesis is not rejected when it is in fact false)
FN ERROR

24
Q

Type II error …….β?

A

Β is the probability of making a type II error. Β is related to statistical power (1-β), which is the probability of rejecting the null hypotephesis when it is false

25
Increase statistical power and decrease β by
1. Increase sample size 2. Increase expected effect size 3. Increase precision of measurement
26
confidence interval - definition
range of values in which a specified probability of the means of repeated samples would be expected to fall
27
confidence interval - equation
CI=mean +-Z (SEM)
28
confidence interval often used
95% CI (corresponding to p=0.05)
29
For the 95% CI: | Z?
Z=1.96
30
For the 99% CI: | Z?
Z=2.58
31
95% CI for a mean difference between variables
if it includes 0 then there is no significant difference and Ho is not rejected
32
95% for ODDS ratio or relative risk
IF it includes 1, Ho is not rejected
33
if the CI between 2 groups overlap
usually NO significant difference exists
34
statistical power (1-β)?
the probability of rejecting the null hypotephesis when it is false
35
Common statistical tests
1. t-test 2. ANOVA 3. Chi-square (x^2)
36
T - test definition / example
Checks differences between MEANS OF 2 groups | - Comparing the mean blood pressure between men and women
37
ANOVA test - definition and example
Checks differences between means of 3 or more groups | - Comparing the mean blood pressure between members of 3 ethnic groups
38
Chi-square (x^2) test - definition and example
Checks differences between 2 or more PERCENTAGES OR PROPORTIONS of categorical outcomes (NOT MEANS) - Comparing the percentage of members of 3 different ethnic groups who have essential hypertension
39
Meta-analysis?
a statistical procedure that integrates the results of several independent studies considered to be combinable
40
t-test vs ANOVA vs CHI-square according to action
t-test --> checks difference between means of 2 groups ANOVA --> Checks differences between means of 3 or more groups CHI-square --> Checks differences between 2 or more percentages or proportions of categorical outcomes (not mean values)
41
t test - types (explain)
independent (nonpaired) -->2 different groups of persons are sampled on one occasion (eg. one group with the drug A, and one group with the drug B) dependent (paired) --> The same persons are sampled on 2 occasions (before and after the treatment)
42
ANOVA - types (explain)
- one way analysis --> 1 variable (eg. weight loss mean in 3 different programs) - 2 way analysis --> 2 variables (eg. weight loss mean in 3 different programs and men vs women)
43
Pearson correlation coefficient (r): range
-1 .....+1
44
the closer the absolute value of r is to 1
the stronger the linear correlation between the 2 values
45
positive vs negative r value -->
positive correlation: as one variable increases, the other variable increases negative correlation:as one variable increases, the other variable decreases
46
Coefficient of determination
r^2 (value that is usually reported)
47
ROC (receiver operating characteristic) - definition and explanation
is a graphic representation between sensitivity (y axis) and 1-specificity (FP rate) (x axis) for a diagnostic test explanation --> the closer the curve is to the diagonia, the less discriminating ability of the test. The closer the curve to the y axis, the better discriminating ability of the test
48
variables - definition
a quantity that changes under different circumstances
49
variables - types and definitions
1. independent variables --> characteristics that an experimenter can change (eg. amount of salt in a diet) 2. dependent variables --> outcomes that reflect the experimental change (blood pressure under different salt regiments)