Factors affecting clearance Flashcards

1
Q

Production of the hormone

A

The more hormones are produced and released in the blood, the harder
it is to clear

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2
Q

Half-life of
the Hormone

A

More significant

Amount it takes for a hormone, or any substance, to decrease its concentration by 50%

Once the hormones are free in the blood (not bound to any proteins), they are more subjected to excretory processes in the kidneys and liver

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3
Q

Clearance Mechanism

A

Degradation by end target organ

Tissue binding

Liver and Kidneys via excretion

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