Fall Quiz 1

Question 1

Brand Name: Zovirax

Answer 1

Generic Name: acyclovir

Question 2

Drug Name: Zovirax/acyclovir

Answer 2

Drug Class: Viral DNA Polymerase Inhibitor

Question 3

Drug Name: Zovirax/acyclovir

Answer 3

ROA: Oral

Question 4

Drug Name: Zovirax/acyclovir

Answer 4

Indications: genital herpes simple; herpes zoster - shingles; varicella - chickenpox; cold sores

Question 5

Drug Name: Zovirax/acyclovir

Answer 5

MOA: acyclic nucleoside analogue of deoxyguanosine that is selectively phosphorylated by the virus-encoded thymidine kinase to its monophosphate form. Cellular enzymes then convert the monophosphate to the active antiviral acyclovir triphosphate, which competitively inhibits viral DNA synthesis by inactivation of viral DNA polymerase and incorporation into and termination of viral DNA replication. Acyclovir has potent activity against HSV I and II and HZV (VZV).

Question 6

Drug Name: Zovirax/acyclovir

Answer 6

Box Warnings: none

Question 7

Drug Name: Zovirax/acyclovir

Answer 7

Contraindications: hyper sensitivity to acyclovir or valacyclovir

Question 8

Drug Name: Zovirax/acyclovir

Answer 8

Adverse Effects: malaise; nausea; vomiting; headache; diarrhea; severity hypersensitivity; renal failure; TTP

Question 9

Brand Name: Tylenol

Answer 9

Generic Name: acetaminophen

Question 10

Drug Name: Tylenol/ acetaminophen

Answer 10

Drug Class: Analgesic

Question 11

Drug Name: Tylenol/ acetaminophen

Answer 11

ROA: Oral

Question 12

Drug Name: Tylenol/ acetaminophen

Answer 12

Indications: pain; headache; fever

Question 13

Drug Name: Tylenol/ acetaminophen

Answer 13

MOA: centrally acting analgesic and antipyretic with minimal anti-inflammatory properties. Its analgesic mechanism is unknown but may be through central inhibition of prostaglandin synthesis.

Question 14

Drug Name: Tylenol/ acetaminophen

Answer 14

Box Warnings: risk of medications errors - injection only; hepatotoxicity

Question 15

Drug Name: Tylenol/ acetaminophen

Answer 15

Contraindications: hypersensitivity to acetaminophen; active acute hepatic dysfunction; do not use with other acetaminophen containing products

Question 16

Drug Name: Tylenol/ acetaminophen

Answer 16

Adverse Effects: nausea; vomiting; pruritus; Stevens- Johnson syndrome; elevated liver function tests

Question 17

Brand Name: Differin/ Plixda

Answer 17

Generic Name: adapalene

Question 18

Drug Name: Differin/ Plixda/ adapalene

Answer 18

Drug Class: Retinoid/ Antiacne

Question 19

Drug Name: Differin/ Plixda/ adapalene

Answer 19

ROA: topical

Question 20

Drug Name: Differin/ Plixda/ adapalene

Answer 20

Indications: acne vulgaris

Question 21

Drug Name: Differin/ Plixda/ adapalene

Answer 21

MOA: exhibits retinoic acid-like activity, reducing important features of the pathology of acne vulgaris by normalizing the differentiation of follicular epithelial cells and keratinization to prevent microcomedone formation. Adapalene enhances keratinocyte differentiation without inducing epidermal hyperplasia and severe irritation, which is associated with retinoic acid. Adapalene decreases formation of comedones, and inflammatory and noninflammatory acne lesions.

Question 22

Drug Name: Differin/ Plixda/ adapalene

Answer 22

Boxed Warnings: none

Question 23

Drug Name: Differin/ Plixda/ adapalene

Answer 23

Contraindications: hypersensitivity

Question 24

Drug Name: Differin/ Plixda/ adapalene

Answer 24

Adverse Effects: dry skin; scaly skin; erythema; burning/ stinging; skin irritation; skin discomfort; pruritus; angioedema

Question 25

Brand Name: Albenza

Answer 25

Generic Name: albendazole

Question 26

Drug Name: Albenza/ albendazole

Answer 26

Drug Class: Antihelmintic

Question 27

Drug Name: Albenza/ albendazole

Answer 27

ROA: Oral

Question 28

Drug Name: Albenza/ albendazole

Answer 28

Indications: parenchymal neurocysticercosis caused by T. solium; cystic hydatid disease of the liver, lung, and peritoneum caused by E. granulosus

Question 29

Drug Name: Albenza/ albendazole

Answer 29

MOA: Selective degeneration of cytoplasmic microtubules in intestinal and tegmental cells of intestinal helminths and larvae. This leads to impaired glucose uptake in parasites, and ATP production decreases leading to energy depletion and death.

Question 30

Drug Name: Albenza/ albendazole

Answer 30

Boxed Warnings: None

Question 31

Drug Name: Albenza/ albendazole

Answer 31

Contraindications: hypersensitivity to albendazole or benzimidazoles

Question 32

Drug Name: Albenza/ albendazole

Answer 32

Adverse Effects: headache; elevated LFTs; nausea; vomiting; abdominal pain; dizziness; diarrhea; alopecia; severe hypersensitivity; renal failure; hepatic failure; aplastic anemia; agranulocytosis; Stevens - Johnson syndrome

Question 33

Brand Name: Proair HFA/ Proventil HFA/ Ventolin HFA

Answer 33

Generic Name: albuterol

Question 34

Drug Name: Proair HFA/ Proventil HFA/ Ventolin HFA/ albuterol

Answer 34

Drug Class: Selective β2-Adrenergic Agonist

Question 35

Drug Name: Proair HFA/ Proventil HFA/ Ventolin HFA/ albuterol

Answer 35

ROA: Oral; Inhalation

Question 36

Drug Name: Proair HFA/ Proventil HFA/ Ventolin HFA/ albuterol

Answer 36

Indications: asthma; chronic obstructive pulmonary disease

Question 37

Drug Name: Proair HFA/ Proventil HFA/ Ventolin HFA/ albuterol

Answer 37

MOA: selective β2-adrenergic agonist that acts on β2-adrenergic receptors of intracellular adenylyl cyclase to increase cyclic AMP levels resulting in bronchial smooth muscle relaxation.

Question 38

Drug Name: Proair HFA/ Proventil HFA/ Ventolin HFA/ albuterol

Answer 38

Boxed Warnings: None

Question 39

Drug Name: Proair HFA/ Proventil HFA/ Ventolin HFA/ albuterol

Answer 39

Contraindications: hypersensitivity

Question 40

Drug Name: Proair HFA/ Proventil HFA/ Ventolin HFA/ albuterol

Answer 40

Adverse Effects: nausea; pharyngitis; rhinitis; throat irritation; upper respiratory tract infections; tremor; nervousness; angina; tachycardia; hypokalemia; insomnia; cough; headache; viral lower respiratory infections; paradoxical bronchospasms; pulmonary edema; atrial fibrillation

Question 41

Brand Name: Fosamax/ Binosto

Answer 41

Generic Name: alendronate

Question 42

Drug Name: Fosamax/ Binosto/ alendronate

Answer 42

Drug Class: Bisphosphonate

Question 43

Drug Name: Fosamax/ Binosto/ alendronate

Answer 43

ROA: Oral

Question 44

Drug Name: Fosamax/ Binosto/ alendronate

Answer 44

Indications: postmenopausal osteoporosis; osteoporosis - male; glucocorticoid induced osteoporosis in those with daily dosages of 7.5 mg or more of prednisone treatment; Paget disease

Question 45

Drug Name: Fosamax/ Binosto/ alendronate

Answer 45

MOA: binds to bone hydroxyapatite and, at the cellular level, inhibits osteoclast activity, thereby inhibiting bone resorption and modulating bone metabolism.

Question 46

Drug Name: Fosamax/ Binosto/ alendronate

Answer 46

Boxed Warnings: None

Question 47

Drug Name: Fosamax/ Binosto/ alendronate

Answer 47

Contraindications: esophageal abnormalities; hypersensitivity; hypocalcemia; inability to sit or stand upright for at least 30 minutes; increased risk for adverse esophageal effects

Question 48

Drug Name: Fosamax/ Binosto/ alendronate

Answer 48

Adverse Effects: fever; gastric ulcer; decreased serum calcium; myalgia; bone pain; esophageal ulcer; abdominal pain; constipation; diarrhea; flatulence; indigestion; headache; osteonecrosis of the jaw; esophageal cancer; immune hypersensitivity; arrhythmia; fractures