farmacotherapie Flashcards

(42 cards)

1
Q

Parasympathomimetica

A

Bootsen werking parasymp. na

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2
Q

Parasympathicolytica

A

Remt werking parasymp.

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3
Q

Sympathicomimetica

A

Bootsen werking sympaticus na

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4
Q

Sympathicolytica

A

Remmen werking sympaticus

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5
Q

Muscarine receptor affiniteit

A

1) muscarine
2) acetylcholine
3) Nicotine

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6
Q

Nicotine receptor affiniteit

A

1) nicotine
2) acetylcholine
3) nicotine

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7
Q

Muscarine receptor plaats

A

M1 - CZS, perifere zenuwen
M2 - hart, zenuwen
M3 - exocriene klieren, gladde spieren

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8
Q

Parasympathomimetica VB

A

Pilocarpine, bethanechol, neostigmine, pyridostigmine, neostigmine, rivastigmine

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9
Q

Pilocarpine

A

glaucoom / miose

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10
Q

Bethanechol

A

urineretentie

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11
Q

Neostigmine

A

Herstel spierverslapping / myasthenia gravis

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12
Q

Pyridostigmine

A

Myasthenia gravis

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13
Q

Rivastigmine

A

Alzheimer

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14
Q

Muscarine agonisten bijwerkingen

A
Diarree
Zweten
Miosis
Misselijkheid
Urinelozing
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15
Q

Botulinetoxine A

A

Blokkade ACh afgifte en verlamming cholinerge zenuwen. Herstel wanneer nieuwe zenuweindigingen zich ontwikkelen

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16
Q

a-adrenoreceptor affiniteit

A

1) noradrenaline
2) adrenaline
3) isoprenaline

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17
Q

B1-adrenoreceptor affiniteit

A

1) isoprenaline
2) adrenaline
3) noradrenaline

18
Q

B2-adrenoreceptor affiniteit

A

1) isoprenaline

2) adrenaline

19
Q

A1 adrenoreceptor agonisten

A

Adrenaline, noradrenaline, fenylephrine

20
Q

A2 adrenoreceptor agonisten

A

Adrenaline, noradrenaline, clonidine

21
Q

A1-adrenoceptor agonisten

A

Adrenaline, noradrenaline, fenylephrine

22
Q

A2-adrenoceptor agonisten

A

Adrenaline, noradrenaline, clonidine

23
Q

A1-adrenoceptor agonisten - farmacologische effecten

A
Vasoconstrictie
Verhoging perifere weerstand
Verhoging bloeddruk
Mydriasis
Sluiting van de urineblaas sprinter
24
Q

A1-adrenoceptor agonisten - therapeutisch gebruik

A
Lokale bloeding
Verkoudheid
Inductie mydriasis
Verlenging werking lokale anaesthetica
Shock
25
A2-adrenoceptor agonisten- farmacologische effecten
Verminderde transmitter afgifte - presynaptisch Vasoconstrictie Verminderde insuline afgifte
26
B1-adrenoceptor agonisten
Adrenaline Noradrenaline Isoprenaline Dobutamine
27
B2-adrenoceptor agonisten
Adrenaline Isoprenaline Salbutamol
28
B1-adrenoceptor agonisten - farmacologische effecten
Hartfrequentie omhoog Hartcontractiliteit omhoog Geleiding in het hart omhoog Renine afgifte omhoog
29
B1-adrenoceptor agonisten - therapeutisch gebruik
Hartstilstand | Hartblok
30
B2-adrenoceptor agonisten - farmacologische effecten
``` Vasodilatatie Perifere weerstand omlaag Verslapping bronchitis Verslapping baarmoeder Glycogenolyse omhoog Glucagon afgifte omhoog ```
31
B2-adrenoceptor agonisten therapeutisch gebruik
Astma | Dreigende vroeggeboorte
32
A1-adrenoceptor antagonisten
Fentolamine Phenoxybenzamine Prazosine Doxazosine
33
A2-adrenoceptor antagonisten
Fentolamine Phenoxybenzamine Yohimbine
34
A1 andrenoceptor antagonisten - farmacologische effecten
``` Vasodilatatie Verlaging perifere weerstand Verlaging bloeddruk Relaxatie prostaat Opening urineblaas sphincter ```
35
A1 adrenoceptor antagonisten - therapeutisch gebruik
``` Hypertensie (geen fentolamine) Prostaat hypertrofie Phaeochromocytoom Perifeer vastrijden Impotentie ```
36
A2-adrenoceptor antagonisten
Verhoging transmitter afgifte | Verhoging insuline afgifte
37
B1 en B2 adrenoceptor antagonisten
Propranolol | Pindolol
38
B1 adrenoceptor antagonisten
Atenolol | Metoprolol
39
A1, B1, B2 adrenoceptor antagonist
Labetalol | Carvedilol
40
B1-adrenoceptor antagonisten - farmacologische effecten
Verlaging hartslag Verlaging hartcontractiliteit Vertraging hartgeleiding Vermindering renine afgifte
41
B1-adrenoceptor antagonisten - therapeutisch gebruik
``` Hartritmestoornissen Secundaire preventie hartinfarct Angina pectoris Hypertensie Migraine profylaxe Angsttremoren Glaucoom ```
42
A en B adrenoceptor antagonist - therapeutisch gebruik
Phaeochromocytoom | Hypertensieve crisis