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BACT211 IRR1 > Fastidious > Flashcards

Fastidious Flashcards

(75 cards)

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1
Q

Require growth factors

A

X and v factor

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2
Q

Non-motile, facultatively anaerobic, oxidase and catalase positive, nitrate reductase positive

A

Haemophilus

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3
Q

Phenomenon observed in species requiring V factor

A

Satellitism

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4
Q

Erroneously implicated in the influenza pandemic of 1889-1890

A

Haemophilus influenzae

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5
Q

What are the virulence factors of Haemophilus influenzae?

A
  • capsule
  • IgA protease
  • adherence mechanism
  • outer membrane proteins
  • lipopolysaccharide
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6
Q

Causes osteoarthritis in children

A

Kingella kingae

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7
Q

Bleach like odor

A

Haemophilus influenzae

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8
Q

Legionella requires ______ for growth

A

L-cysteine

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9
Q

Mushroom odor

A

Haemophilus influenzae

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10
Q

Pinkeye conjunctivitis

A

Haemophilus aegypticus

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11
Q

Urine specimen for Ag detection

A

Legionella

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12
Q

What are the two patterns of H. influenzae?

A
  • Encapsulated strains
  • unencaosulated strains
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13
Q

Haemophilus influenzae serotype b (HIB) in children

A

Meningitis

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14
Q

Rapid onset, acute inflammation, intense edema of the epiglottis

A

Epiglottitis

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15
Q

Life threatening disease in children

A

Bacterial tracheitis

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16
Q

What is other name of harmophilus aegypticus?

A

Koch-Weeks bacillus

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17
Q

Observed in conjunctivitis exudates from egyptians by koch in 1883

A

Haemophilus aegypticus

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18
Q

Associated with pinkeye conjunctivitis

A

Haemophilus aegypticus

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19
Q

Agent of chancroid, type of genital ulcer disease

A

Haemophilus ducreyi

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20
Q

Infects mucosal epithelium, genital and nongenital skin, and regional lymph nodes

A

Haemophilus ducreyi

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21
Q

Endocarditis of insidious onset

A

Haemophilus parainfluenzae

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22
Q

Pharyngitis

A

Haemophilus parahaemolyticus

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23
Q

What are the specimen for Haemophilus?

A
  • Blood
  • CSF
  • middle ear exudate
  • joint fluids
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24
Q

What we can use for response specimens

A

CAP supplemented with bacitracin (300 mg/L)

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25
For H. aegypticus and H. ducreyi what media can we use ?
CAP supplemented with 1% Iso-VitaleX or Vitox
26
Translucent, tannish, moist, smooth, convex, with distinct odor
Haemophilus influenzae
27
Small, flat, smooth, nonmucoid, transparent to opaque, tan or yellow
Haemophilus ducreyi
28
School of fish or railroad tracks appearance
Haemophilus ducreyi
29
Used to differentiate heme-producing species of Haemophilus
Porphyrin test
30
Test the ability of the organisms to convert d-aminolevulinic acid (d-ALA) into porphyrins or porphobilinogens
Porphyrin test
31
Cannot synthesize heme and are not X factor positive (required hemin)
Porphyrin negative
32
Can synthesize heme and x factor negative
Porphyrin positive
33
What reagent is addrd to porphobilinogen?
Kovac’s reagent
34
HACEK
H - Haemophilus A - aggregatibacter, actinomycetemcomitans, A. aphrophilus C - cardiobacterium hominis E - eikenella corrodens K - kingella spp
35
Found in dental plaque and gingival scrapings Colonies are conves, granular, and yellow with an opaque zone near the center of CAP
Aggregatibacter aphrophilus
36
Isolated from blood, lung tissue, abscessess of the mouth and brain Isolated grow better in increased carbon dioxide
Aggregatibacter actinomycetemcomitans
37
Form rosettes, swellings, long filaments or sticklike structures in yeast extract
Cardiobacterium hominis
38
Agar pitting colonies
Cardiobacterium hominis
39
Cellulitis in drug addict Implicated in periodontitis, meningitis, empyema, pneumonia, osteomyelitis, arthritis
Eikenella corrodens
40
Members are coccobacillary to short bacilli with swuared ends that occur in paird or short chains Grows on Thayer-Martin agar
Kingella
41
Has been associated with bacteremia and abscesses
Kingella dinitrificans
42
Important pathogrn in pediatric population
Kingella kingae
43
Systemic and pneumonic forms are possible but cutaneous infection resulting from animals bites is common
Pasteurella
44
What is the most common specie of pasteurella?
Pasteurella multocida
45
Also known as mediterranean, crimean, malta fevers
Brucella
46
Nonspecific symptoms occur within 1-4 weeks of exposure
Acute infection
47
Undulating fevers, arthritis and epididymoorchitis
Subchronic or undulant form
48
Depression, arthritis, and chronic fatigue syndrome
Chronic form
49
Four common isolated species of brucella
Brucella melitensis Brucrlla abortus Brucella suis Brucella canis
50
B. abortus natural host
Cattle
51
Brucella suis natural host
Swine
52
B. melitensis natural host
Goat or sheep
53
B. canis natural host
Dogs
54
Most common specie of francisella
Francisella tularensis
55
Zoomotic disease also known as rabbit fever, deerfly fever, lemming fever, water rat trappers’ disease
Tularemia
56
Associated with nosocomial infection.
Legionella
57
Most common specie of legionella
Legionella pneumophila
58
Found in lakes, rivers, hot springs, and mud
Legionella
59
Media used for isolation of legionella
Buffered charcoal yeast extract agar BCYE with L-cysteine
60
On BCYE the colonies appear
Grayish white, blue-green, convex, glistening.
61
Ground glass appearance
Legionella
62
What are the rapid methods?
- urine antigen test - direct fluorescent antibody rest
63
Detection of legionella antigen in urine specimen using radioimmunoassay and enzyme immunoassay
Urine antigen test
64
Fluorescein isothiocyanate labelled antibodies bind to antigens on the cell surface, and the Ag-Ab complexexls are detected using fluorescent microscope
Direct fluorescent antibody test
65
Primary human pathogens
Bordetella pertussis and borderella parapertussis
66
Causes whooping cough or pertussis
Bordetella
67
Opportunistic pathogen
Bordetella bronchiseptica
68
What are the virulence factors of bordatella
- filamentous hemagglutinin - pertactin - pertussis toxin - tracheal cytotoxin
69
Nonspecific signs; infection is highly communicable
Catarrhal phase
70
Sudden onset of severe, repetitive coughing followed by fever ye characteristics “whoop” at the end of coughing spell
Paroxysmal phase
71
Decrease in frequency and severity of coughing spells
Convalescent phase
72
Human disease with no animal reservoir or vector Acquired through respiratory droplet or direct contact with secretion
Pertussis
73
One of the most highly communicable diseases of childhood
Pertussis
74
Respiratory tract pathogen of animals includding dogs, in which it causes kennel cough
Bordetella bronchiseptica
75
Specimen of choice for brucella
Nasopharyngeal aspirates or swabs

BACT211 IRR1 (6 decks)

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