Febrile Child Flashcards
(49 cards)
Fever in children <2mo
100.4 F (38 C)
Fever in children >2mo-<3yo
102.2 (39)
Why is there an increased risk for SBI in children <60d
- Immune system immaturity
- Age specific pathogens
Most important component of PE in febrile child
General “look” of pt.
Examples of SBI
- Meningitis
- Bacteremia/sepsis
- UTI/pyelo
- Pneumonia
- Cellulitis
- Abscess
- Septic arthritis
- Osteomyelitis
- Bacterial enteritis
Ddx in well-appearing febrile child
- UTI
- Bacteremia
- Meningitis
- Pnuemonia
- SSTI
- Bacterial enteritis
- Bone & joint infections (osteo, septic arthritis)
- Enterovirus
- URTI
- Bronchiolitis
- Viral GE
- Neonatal HSV
Ddx in ill-appearing febrile child
- SBI
- Neonatal HSV
- Enterovirus
- RSV
- Ductal dependent R an L sided obstructive lesions
- Inborn erros of metabolism
- Congenital adrenal hyperplasia
- Malrotation w/ volvulus
Most common microbial etiology of septic arthritis
S. aureus
ABX used to treat osteomyelitis and septic arthritis (neonates, older children, adolescents)
Neonates: oxacillin + gentamicin
Older children: oxacillin + clindamycin
Adolescents: ceftriaxone
What patient population (age, sx) gets automatic admission and what type of treatment or w/u do they receive?
- Neonates <4wks w/ fever (treat w/ IV ABX and full sepsis w/u)
- ALL ill-appearing children <3yo w/ fever (full sepsis w/u)
M/C SBI
UTI
M/C microbial etiology of SBI
E. coli
Rates of bacteremia & meningitis are highest in what age group
0-4wks (neonates)
Physical exam is unreliable in what age group(s)
<2 mo
Sepsis RF in neonates
- Premature
- Ill-appearing
- Comorbidity
- Fever >40C
- Maternal infection (fever, prolonged ROM, GBS (+), genital HSV)
- Unimmunized
- Social factors limiting f/u
Common bacterial etiologies in neonates (0-4wks)
- E. coli
- GBS
Common viral etiologies in neonates (0-4wks)
- HSV
- VZV
- Enterovirus
- Influenza
- Adenovirus
- RSV
W/u in febrile neonates
- CBC w/ diff
- CMP
- Blcx
- UA
- Urine cx
- LP
- HSV RF assessment
- Viral testing ONLY if respiratory sx
What ABX do we use to treat non-focal, non-ill-appearing neonates w/o CSF infection?
Gentamicin + ampicillin
What ABX do we use to treat ill-appearing neonates w/ CSF infection/pleocytosis?
Ceftazidime + ampicillin
Common bacterial etiologies in infants (4-8wks)
- S. pneumo
- E. coli
- N. meningitidis
- HIB (rare d/t vaccine)
What is the purpose of the Rochester & Philadelphia criteria?
Determine low risk of SBI in infants 4-8wks
Rochester criteria (4-8wk infants)
- Well-appearing
- Full term infant
- NO prior h/o illness, ABX, hyperbilirubinemia, hospitalization
- No skeletal, soft tissue, skin, or ear infections
- CBC normal
- Other: fecal leukocytes <5 WBC if diarrhea, urine WBC <10
Philadelphia criteria (4-8wk infants)
- Well-appearing
- Reassuring exam
- WBC <15,000
- Band to neutrophils <0.2 ratio
- UA <10 WBC
- (-) urine GS
- CSF <8 WBC
- (-) CSF GS
- (-) CXR (no infiltrate) - if obtained
- Stool (-) blood and few to no leukocytes on smear - if obtained