Feline Neurology Flashcards

(40 cards)

1
Q

What are some components of the feline neuro exam?

A

Mentation
Behavior
Posture
Gait
Cranial Nerves
Postural Reactions
Sensation
Evaluate gate, hopping, wheel barrow, paw placement

1/3 cat don’t have cutaneous trunci so need to pluck single hair not pinch to test this

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2
Q

What percent of cats wont have a menace?

A

1/3

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3
Q

Feline Hyperesthesia Syndrome
Age:
Diagnostic Test Results:
Clinical Signs:
Treatment:

A

Age: 1 yr
Diagnostic Test Results: All normal
Clinical Signs: Tail flicking, head shaking, hallucination, self-mutilate
Treatment: Gabipentin (2/3 patients), clomipramine, amitripramine, Amitriptyline, Phenobarbital, Pred, Meloxicam

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4
Q

Feline Idiopathic Epilepsy
Age:
When:
Signs:
Seizure Characteristics:
Treatment:
Prognosis:

A

Age: <7yr
When: During resting conditions
Signs: Rapid running, erratic, chase and circle
Seizure Characteristics: Not status epilepticus, normal interictal
Treatment: Phenobarbital or Levetiracetam (Keppra)
*Watch for pseudolympoma - stop phenobarbital and it stops
Prognosis: Poor if patient is older, 70% respond to AED, 20% euth and 40% complete remission of seizure

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5
Q

Audiogenic Reflex Seizure
Definition:
Signs:
Breed Predisposition:
Age:
Trigger:
Treatment:

A

Definition: seizure that objectively and consistantly precipitated by enviromental or internal stimuli
Signs: Myoclonic jerk, progress to generalized, noise trigger
Breed Predisposition: Birmans
Age: 10-19yr
Trigger: High pitched noise (glass or foil)
Treatment: Less noise (decrease 75%), Keppra, phenobarbital

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6
Q

Hippocampal Necrosis
Signs:
Diagnosis:
Treatment:

A

Signs: Focal Facial Seizure, Hypersalivation and Aggressiveness
Diagnosis: MRI/Autoantibody titer - see necrosis, inflammatory cells, immune mediated response
Treatment: Phenobarbital, Levetiracetam, Combo, Prednisolone (Refractory to meds)
Worst type of seizure

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7
Q

What are some common CNS infections in cats?

A

FIP, Toxoplasmosis, Cryptococcus, FeLV, FIV, Panleukopenia

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8
Q

Feline Infectious Peritonitis: What virus must the cat get to have the mutation that causes FIP?

A

Feline Corona Virus

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9
Q

Feline Infectious Peritonitis: Where does this virus like to replicate?

A

Macrophages resulting in immune mediated vasculitis

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10
Q

Feline Infectious Peritonitis: It is the most common CNS disease of brain and spinal cord. True/False

A

Ture

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11
Q

Feline Infectious Peritonitis: Who is commonly effected?

A

Pedigree up to 4 years, breeding colony, rescue center

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12
Q

Feline Infectious Peritonitis: What are some clinical signs?

A

Anterior chamber hemorrhage and vascular cuffing (Disease of brain - see in eye since it is an extension of the brain.)

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13
Q

Feline Infectious Peritonitis: How do you diagnose it?

A

MRI - fluid in 3rd ventricle that is swollen/CSF tap

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14
Q

Feline Infectious Peritonitis: Is there a treatment?

A

Yes, it is fatal without it
Antiviral adenosine nucleoside analogue GS

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15
Q

Toxoplasmosis:
Who is the natural host?

A

The cat

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16
Q

Toxoplasmosis:
What stage causes pathology?

A

Bradyzoites make cysts in the brain, spinal cord or skeletal muscles

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17
Q

Toxoplasmosis:
What are some clinical signs?

A

Neurologic and ocular (anterior uveitis)

18
Q

Toxoplasmosis:
How do you diagnose it?

A

Serology +/- PCR

19
Q

Toxoplasmosis:
What is the treatment?

A

Clindamycin or Trimethoprim Sulphonamide with a folic acid supplement

20
Q

Toxoplasmosis:
Prognosis?

A

Good if treated early

21
Q

Cryptococcus:
What type of pathogen is it?

A

Fungus (saprophytic yeast (soil and pigeon feces)

22
Q

Cryptococcus:
Route of transmission?

23
Q

Cryptococcus:
Clinical signs?

A

Lethargy, behavioral changes, gait abnormalities, vestibular sign, seizure (Roman Nose), retinal detachment

24
Q

Cryptococcus:
How do you diagnose it?

A

Serology, CSF, Fungal culture

25
Cryptococcus: Treatment?
Fluconazole, Prednisone, amphotericin B and Flucytosine
26
What are some viral feline infecitons?
FeLV, FIV (neurotopic, see perivascular cuffing and glial nodules, alter sleep pattern, CNS change), FPV, feline parvo
27
What is Feline Parvo Virus (panleukemia)?
Cerebellar hypoplasia, in utero infection, perinatal infection, vaccination of a pregnant queen with live FPV, non-progressive disorder, no inflammatory change in brain, forebrain lesion, retinal damage Prognosis: happy life
28
What are clinical signs of Feline Ischemic Encephalopathy?
Acute Blindness - central, good PLR
29
What do they think is the cause of FIE?
Cuterebra migration
30
What can you see on the histology of a cat with FIR?
Line of destruction of tissue
31
What is the treatment for FIE?
Ivermectin, prednisone, diphenhydramine
32
When is FIE commonly seen?
Aug, July, Sept
33
What is global cerebral Ischemia? Clinical signs? Prognosis? Hx?
Jaw completely open and ecludes Signs: Blind, seizure, obtunded, seizure Prognosis: poor Maxiallry artery blocked to brain Dental? not reversible, hypokalemia, hypothyroid
34
What artery is occluded in Global Cerebral Ischemia?
Maxillary
35
What causes Cervical Ventroflexion?
No nuchal ligament - diffuse weakness Hypokalemia = renal disease - stone Treat with ammonium chloride Thiamine Deficiency, Myasthenia gravis, hyperthyroidism, hepatic encephalopathy
36
Which type of cancer is most common in cats?
Meningioma
37
How progressive is meningioma?
Very - dont know until bad (22-38 from signs to diagnosis)- seizures
38
What is the median survival time with medical therapy?
18 days
39
What are clinical signs of a meningioma?
Behavior change, seizures, ataxia, visual impairments
40
Where does lymphosarcoma like to localize to?
Spinal cord and brain (bone marrow, kidney, liver, spleen, lymph nodes)