Female Reproductive Flashcards
(25 cards)
What hormones mark the follicular phase?
Estrogen. Slight bump of FSH at beginning. 0-14 days
What hormones mark the luteal phase?
Estrogen, progesterone, inhibin. 14-28 days
When does the LH surge take place?
Day 14
How does estrogen affect the release of LH?
Inhibits before ten days, stimulates after
What phase of meiosis are oocytes frozen in at birth?
Prophase 1
Where are primordial follicles found?
Only in the cortex
What is the theca interna rich in?
Capillaries
What makes the zona pellucida, and what does it do?
Oocyte and granulosa cells. Prevents penetration by multiple sperm. Is glycoprotein
What are primordial follicles activated by?
BMP4, FGF, LIF, SCF
Layers of primary follicle from out to in?
Theca externa(capsule, no hormones), theca interna(capillaries here, hormones), BL, granulosa cells, zona pellucida, oocyte
FSH is regulated by what?LH?
Estrogen and progesterone. Only estrogen
What is the main function of progesterone?
Thickens endometrium and prevents beginning of new cycle
Which cells in corpus luteum secrete progesterone?
Granulosa cells
What happens to corpus luteum in pregnancy? Not?
Saved and enlarges. Eaten by macrophages
Explain PCOS?
Thick capsule forms around oocyte, no estrogen or progesterone, male characteristics.
Where does fertilization occur?
In ampulla of oviduct
What are the two layers of the endometrium?
Functionalis that is shed, stratum basalis is that regenerates functionalis
What do glands in uterus look like during secretory phase?
Serrated
What does uterine hyperplasia do to cancer risk?
Ups significantly. PCOS can cause
What does vagina produce? How do bacteria use it?
Glycogen. Acidic environment made
Does estrogen produce more acidophils?
Yes
What rescues the corpus luteum?
hCG, which is secreted by blastocyst
What is the purpose of the chorionic villi of placenta?
Keep maternal and fetal blood separate. Fetal in syncytiotrophoblast, maternal in inside cytotrophoblast
How does progesterone affect prolactin?
Inhibits it and lactation