Fertilsation and assisted reproductive technologies Flashcards

1
Q

Where does fertilisation normally take place?

A

In the ampulla of the fallopian tube

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2
Q

Where do the sperm bind on the zona pellucida?

A

ZP3 sites

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3
Q

What happens when the 1st sperm through fuses with the membrane of the ovum?

A

intracellular Ca is released in oocytewhich induces meisosis II and makes surrounding membrane impenetrable

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4
Q

What is considered subfertility in men?

A
- low sperm count/motility
testicular disease
 - abnormalities with Vas Deferens
 - smoking
 - obesity
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5
Q

What could lead in subfertility in females?

A
  • oligomenorrhoea
  • uterine/ fallopain tube pathologies
  • PCOS
  • endometriosis
  • previous PID/STIs
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6
Q

What are the 5 types of assisted reproductive techniques?

A
  • artificial insemination by donor
  • in vitro fertilisation
  • gamete intrafallopian transfer (GIFT)
  • intracytoplasmic sperm injection (ICSI)
  • zona drilling
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