Fetal Complications Flashcards

(30 cards)

1
Q

How common is multiple pregnancy?

A

>Incidence because of assisted fertility treatment

1/80 pregnancies are twins

1/4000 pregnancies are triplets

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2
Q

Splitting of the embryo at 0-3 weeks results in what class of twins?

A

(Separate chorion and amnion)

Dichorionic and diamniotic

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3
Q

Splitting of the embroy at 3-8 weeks results in what type of twins?

A

(Shared chorion)

Monochorionic and diamniotic

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4
Q

Splitting of the embryo at 8-12 weeks results in what class of twins?

A

(Shared amnion and chorion)

Monochorionic and monoamniotic

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5
Q

Splitting of the embryo at 12+ weeks results in what class of twins?

A

Shared body, conjoined

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6
Q

What is the chorion?

A

Placenta

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7
Q

What is the amnion?

A

Amniotic sac

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8
Q

Give the maternal complications of multiple pregnancy

A

Miscarriage

Hyperemesis

Anaemia

Pre-eclampsia

Gestational diabetes

Operative delivery

Post-natal depression

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9
Q

Give the fetal complications of multiple pregnancy

A

Twin-twin transfusion syndrome

Congenital Abnormalities

Malpresentation

Locked Twins

IUD

IUGR

Preterm labour and low birth weight

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10
Q

What is twin-twin transfusion syndrome?

A

Anastomosis between vessels occurring in shared placenta/Mono-chorionic twins

Recipient gets cardiac failure, polyhydramnios

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11
Q

What is intrauterine growth restriction (IUGR)?

A

Low birthweight infants (below 10th centile), may be constitutionally small or growth restricted due to pathological process

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12
Q

What can cause IUGR?

A

Maternal

  • Poor nutrition
  • Smoking
  • Alcohol and drug abuse
  • Maternal disease

Fetal

  • Abnormality
  • Infection

Placental

  • Failure of trophoblast invasion, leading to reduced oxygen transfer to the fetus
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13
Q

What is assessed on US to diagnose IUGR?

A

Fetal size

Oligohydramnios

Doppler for blood supply

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14
Q

What is intrauterine death?

A

Birth of an infant >24 weeks gestation with no signs of life

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15
Q

How common is IUD?

A

1/200 births

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16
Q

Give fetal causes of IUD

A

Chromosomal abnormalities

Infection

Umbilical cord accidents

Twin-twin transfusion syndrome

17
Q

Give maternal causes of IUD

A

Chronic disease

Obstetric cholestasis

Rhesus disease

Thrombophilia

18
Q

Give placental causes of IUD

A

Abruption

Pre-eclampsia

Smoking

19
Q

What is reduced fetal movements?

A

<10 movements within 2 hours in pregnancies >28 weeks gestation is indication for further assessment

20
Q

When should fetal movements be established?

A

By 24 weeks

Usually occurs between 18-20, which increases until 32 weeks gestation where they begin to plateau

21
Q

Give risk factors for reduced fetal movements

A

Posture

  • More prominent lying down and less when sitting and standing

Placental position

  • Patient with anterior placentas prior to 28 weeks gestation may have decreased awareness of movements

Medication

  • Alcohol
  • Opiates
  • Benzodiazepines

Fetal position

  • Anterior fetal position means movements are less noticeable

>BMI

  • Less likely to feel prominent fetal movements

Amniotic fluid volume

  • Oligohydramnios
  • Polyhydramnios

Fetal size

22
Q

What investigations are used in reduced fetal movements?

A

Doppler to confirm fetal heartbeat

CTG for 20 minutes if heartbeat detectable

Immediate US if no detectable heartbeat

23
Q

What is the most common cause of early-onset severe infection in the neonatal period?

A

Group B Streptococcus (GBS)

24
Q

What is the management for women who have had GBS detected in previous pregnancies?

A

Offered intrapartum antibiotic prophylaxis (IAP) or testing in late pregnancy and then antibiotics if still positive

25
When are GBS swabs carried out?
35-37 weeks or 3-5 weeks prior to the anticipated delivery date
26
When should IAP (intrapartum antibiotic prophylaxis) be offered (GBS)?
To women with a previous baby with early or late onset GBS disease To women in preterm labour regardless of their GBS status Women with a pyrexia during labour (\>38ºC)
27
What is the antibiotic of choice in GBS prophylaxis?
Benzylpenicillin
28
Give risk factors for GBS
Prematurity Prolonged rupture of the membranes Previous sibling GBS infection Maternal pyrexia, for example secondary to chorioamnionitis
29
What causes oligohydramnios?
Premature rupture of membranes Fetal renal problems e.g. renal agenesis Intrauterine growth restriction Post-term gestation Pre-eclampsia
30
Give risk factors for sudden infant death syndrome
Prone sleeping Parental smoking Bed sharing Hyperthermia and head covering Prematurity