Fibroadenomas Flashcards
(30 cards)
What are fibroadenomas?
Fibroadenomas are the most common benign tumour of the breast.
Traditionally referred to as ‘breast mice’, these discrete, mobile lumps often occur in younger women. It is important to distinguish and exclude breast cancer, as such patients should be referred for a triple assessment in line with NICE guidance. - what is this referring to?
Fibroadenomas - Traditionally referred to as ‘breast mice’, these discrete, mobile lumps often occur in younger women. It is important to distinguish and exclude breast cancer, as such patients should be referred for a triple assessment in line with NICE guidance.
As a general rule, in fibroadenomas - …% regress spontaneously, …% will remain unchanged and 25% will get bigger.
As a general rule, 50% regress spontaneously, 25% will remain unchanged and 25% will get bigger.
Fibroadenomas most commonly occur in women aged … to …
Fibroadenomas most commonly occur in women aged 14 to 35.
Fibroadenomas are typically seen in … patients and often regress after ….
Fibroadenomas are typically seen in younger patients and often regress after menopause. There is up to a 10% lifetime incidence of fibroadenomas in women.
There is up to a …% lifetime incidence of fibroadenomas in women.
There is up to a 10% lifetime incidence of fibroadenomas in women.
Fibroadenoma may be split into a number of sub-types. These include: (3)
These include:
Simple fibroadenomas: These are small (1-3cm) lumps with classical features of a firm, mobile and painless lump.
Complex fibroadenomas: Complex appearance on histopathology. These have been associated with a slight increase in the risk of breast cancer.
Giant fibroadenomas: Large fibroadenomas growing to a size of greater than 5cm. Difficult to distinguish from a phyllodes tumour.
Simple fibroadenomas: These are small (…-…cm) lumps with classical features of a firm, mobile and … lump.
Simple fibroadenomas: These are small (1-3cm) lumps with classical features of a firm, mobile and painless lump.
Complex fibroadenomas: Complex appearance on histopathology. These have been associated with a slight increase in the risk of ….
Complex fibroadenomas: Complex appearance on histopathology. These have been associated with a slight increase in the risk of breast cancer.
Giant fibroadenomas: Large fibroadenomas growing to a size of greater than …cm. Difficult to distinguish from a phyllodes tumour.
Giant fibroadenomas: Large fibroadenomas growing to a size of greater than 5cm. Difficult to distinguish from a phyllodes tumour.
Fibroadenomas are fibroepithelial tumours arising from … and epithelial tissue.
Fibroadenomas are fibroepithelial tumours arising from stromal and epithelial tissue.
Fibroadenomas - There is clear evidence of a hormonal link. They tend to develop after menarche and regress after menopause. They may be triggered or increase in size during … or when taking ….
Fibroadenomas - There is clear evidence of a hormonal link. They tend to develop after menarche and regress after menopause. They may be triggered or increase in size during pregnancy or when taking hormone replacement therapy (HRT).
… - A genetic basis has also been identified with a mutation to MED12 found in around 60% of tumours. MED12 has been implicated in many other conditions including uterine fibroids.
Fibroadenomas - A genetic basis has also been identified with a mutation to MED12 found in around 60% of tumours. MED12 has been implicated in many other conditions including uterine fibroids.
Fibroadenomas present with a breast lump which is typically …
Fibroadenomas present with a breast lump which is typically painless.
They classically occur on the outer, upper quadrant of the breast. In general, the breast lump can be described as: Painless Firm Mobile What is this referring to?
Fibroadenomas They classically occur on the outer, upper quadrant of the breast. In general, the breast lump can be described as: Painless Firm Mobile
In up to …% of cases, there are multiple fibroadenomas affecting one or both breasts.
In up to 20% of cases, there are multiple fibroadenomas affecting one or both breasts.
Fibroadenomas present with a breast lump that can be described as … (3)
They classically occur on the outer, upper quadrant of the breast. In general, the breast lump can be described as:
Painless
Firm
Mobile
NICE have set out criteria to guide referral for patients with symptoms suggestive of breast cancer.
Patients should be referred on a two-week wait suspected cancer pathway if:
30 and over and have an unexplained breast lump with or without pain or
50 and over with any of the following symptoms in one nipple only:
Discharge
Retraction
Other changes of concern
NICE also recommend clinicians consider a two-week wait suspected cancer pathway for people:
With skin changes that suggest breast cancer or
Aged 30 and over with an unexplained lump in the axilla
Consider non-urgent referral in people aged under …. with an unexplained breast lump with or without pain.
Consider non-urgent referral in people aged under 30 with an unexplained breast lump with or without pain.
The one-stop breast clinic incorporates a … assessment in one appointment. It requires localities to have access to appropriate specialists and diagnostic equipment but offers patients a convenient and efficient service.
The one-stop breast clinic incorporates a triple assessment in one appointment. It requires localities to have access to appropriate specialists and diagnostic equipment but offers patients a convenient and efficient service.
The ..-.. breast clinic incorporates a triple assessment in one appointment.
The one-stop breast clinic incorporates a triple assessment in one appointment. The majority of patients can be reassured that they do not have evidence of breast cancer following a single visit. Some may need to await further tests (e.g. core biopsy results) whilst others may be given a likely diagnosis.
In young patients (< … years) with a low-risk history; examination and imaging findings - these alone may be sufficient to make a diagnosis of fibroadenoma. In older patients or those with indeterminate (or concerning) examination or imaging, a biopsy must be considered.
In young patients (< 25 years) with a low-risk history; examination and imaging findings - these alone may be sufficient to make a diagnosis of fibroadenoma. In older patients or those with indeterminate (or concerning) examination or imaging, a biopsy must be considered.
Triple assessment in the breast clinic
The one-stop breast clinic incorporates a triple assessment in one appointment. First step involves…
- Clinical history and examination
Each patient referred to the two-week wait one-stop clinic will be reviewed by a specialist. This will involve a detailed history including family history. Following this, the patient will be carefully examined.
