Fin

Question 1

Air pollutants cause which symptoms?

Answer 1

Bronchoconstriction & Pulmonary Edema

Question 2

Which metabolites damage ganglion cells in the retina?

Answer 2

Formate anion

Question 3

Which category of medications will cause signs and symptoms of hypertensive crisis?

Answer 3

Monoamine Oxidase inhibitors

Question 4

Delayed onset pulmonary toxicity is characteristic of which chemical exposure?

Answer 4

Inhalation of an irritant gas w/ low water solubility

Question 5

Methemoglobinemia is characterized by what?

Answer 5

A blood drop on filter paper stains chocolate brown

Question 6

A person using corticosteroids for osteoarthritis over a chronic duration will have peptic ulcers. Why?

Answer 6

Inhibition of prostaglandin synthesis

Question 7

Disulfiram therapy (inhibitor of Aldehyde dehydrogenase) involves the risk of severe cardiovascular and gastro-intestinal effects upon exposure to alcohol. These effects are due to accumulation of which chemical in blood?

Answer 7

Acetaldehyde

Question 8

Carbon monoxide has the greatest binding affinity for which form of hemoglobin?

Answer 8

Fetal Hb

Question 9

Which is an initial effect of inhaling an irritant gas?

Answer 9

Coughing

Question 10

Chronic use of steroidal anti-inflammatory medications will cause which effects?

Answer 10

Ulcers, Hyperglycemia, & Cataracts

ABC correct

Question 11

Which is correct for nitrous oxide?

Answer 11

Oxidizes Hb to form Methemoglobin

Question 12

Aspirin should NOT be used to manage the signs & symptoms of which condition?

Answer 12

Gouty arthritis

Question 13

Chronic use of steroidal anti-inflammatory medications can cause GI ulcers because of inhibition of which enzyme?

Answer 13

Phospholipase A2

Question 14

Carbon monoxide inhalation:

Answer 14

Will reduce the amt of HB available to transport oxygen, can be misdiagnosed as “Flu,” can cause fetal damage.
(A, B, & C are correct)

Question 15

“Mad Hatter’s Disease” is a consequence of chronic exposure to which toxic chemical?

Answer 15

Mercury

Question 16

The risk for Parkinson’s disease and angina is increased upon exposure to which chemical?

Answer 16

Carbon monoxide

Question 17

Daily use of low-doses of aspirin is prescribed to pts to present intra-vascular clotting after cardiovascular surgery; the therapeutic dose to manage pain, fever, and inflammation is around six times this dose. The rationale for this low-dose prescription is?

Answer 17

It inhibits Thromboxane synthetase

Question 18

Cheyne-Stokes respiration is caused by fluctuations in PCO2 levels. This is a characteristic effect of which substance?

Answer 18

Narcotic analgesic overdose

Question 19

Chronic use of which therapeutic agent is most likely to increase the risk for fractures and osteoporosis?

Answer 19

Proton pump inhibitors

Question 20

The dental anesthetic, Nitrous Oxide; “laughing gas”, must be combined w/ adequate oxygen when used to perform dental procedures in order to prevent which?

Answer 20

Methemoglobinemia

Question 21

Carbon monoxide does NOT cause which effect?

Answer 21

Coughing

Question 22

Highly soluble irritant gases pose the highest risk for adverse effects in patients w/ which condition?

Answer 22

Asthma

Question 23

The best confirmation of carbon monoxide poisoning is what?

Answer 23

Carboxyhemoglobin blood levels

Question 24

Which toxic chemical has a sweet taste?

Answer 24

Lead acetate

Question 25

Which category of chemicals will cause liquefactive necrosis upon contact w/ living tissues?

Answer 25

Strong Bases

Question 26

Excessive consumption of which food item will increase risk for mercury poisoning?

Answer 26

Bigeye Tune

Question 27

Which metallic poison causes psychosis?

Answer 27

Mercury

Question 28

Non-steroidal anti-inflammatory medications provide palliative relief by inhibiting which enzyme?

Answer 28

Cyclo-oxygenase

Question 29

Acute overdose w/ aspirin can cause hyperthermia. This occurs b/c of which reason?

Answer 29

Aspirin uncouples oxidative-phosphorylation

Question 30

Even low dose use of aspirin on a chronic basis can increase the risk for GI ulcers b/c of which reason?

Answer 30

Aspirin inhibits cyclo-oxygenase 1 in the gastric mucosa

Question 31

Which is NOT an anti-inflammatory steroid?

Answer 31

Testosterone

Question 32

Overuse of which anti-inflammatory medications will NOT cause signs and symptoms of cushings syndrome?

Answer 32

Aspirin

Question 33

Which anti-inflammatory agents will aggravate gouty arthritis?

Answer 33

Aspirin

Question 34

Reye's syndrome is associated w/ the management of viral fevers in children w/ which anti-pyretic agent?

Answer 34

Aspirin

Question 35

Narcotic analgesic agents will not cause which effect?

Answer 35

Mydriasis

Question 36

Pin point pupil is a characteristic of which substance?

Answer 36

Narcotic

Question 37

A 50-YO pt is under your care and is known to have active peptic ulcers. He has been taking the recommended dose of an analgesic to manage the pain due to osteoarthritis for the past three months and complains of lack of energy. Lab data indicated he is anemic and eexhibits prolonged bleeding time. The most likely analgesic involved is?

Answer 37

Aspirin

Question 38

Exposure to cyanide can cause death as a result of which effect?

Answer 38

Inhibition of cytochrome oxidase (blockade of ATP synthesis)

Question 39

A Pt under you care for asthma exhibits moon facies and buffalo hump, and has mild hyperglycemia. Which Which is the most likely medication that this pt concurrently taking?

Answer 39

Dexamethasone

Question 40

Acute overdose w/ which chemical produces centrilobular hepatic necrosis?

Answer 40

Tylenol