Final

Question 0

Cytoreduction

Answer 0

Kill/remove as many cells as possible

Question 1

Cancer treatments

Answer 1

1. Surgery
2. Radiation therapy
3. Drug therapy

Question 2

Resection

Answer 2

Physical removal of tumor

Question 3

Whipple Procedure

Answer 3

Surgery for pancreatic cancer.

Question 4

Brachytherapy

Answer 4

Isotopes placed in body at tumor site. Prostate cancer

Question 5

External beam therapy

Answer 5

Radiation aimed at tumor site

Question 6

Boron-neutron capture therapy

Answer 6

Neutron is shot at boron that accumulates in the cells

Question 7

Tumors treatable by radiotherapy

Answer 7

Hodgkin’s lymphoma
Non HL
Nasopharyngeal
Testicular

Question 8

Chemotherapy effectiveness response level

Answer 8

1. Complete response
2. Partial response
3. Stable/ Remission
4. Progression

Question 9

Platinum drugs

Answer 9

Carboplatin- ovarian and lung

Oxaliplatin- CRC

Question 10

Nitrogen Mustard

Answer 10

First chemotherapy

Question 11

Nitroso-ureas

Answer 11

Inhibit translation. Kills alkylating agent resistant tumors

Carmustine Lomustine Streptozocin

Question 12

Alkylating agents

Answer 12

Temozolamide
Thiotepa
Altretamine
Decarbazine
Procarbazine

Question 13

Antibiotics from Streptomyces

Answer 13

Anthracyclins
Actinomycin D
Bleomycin
Mitomycin

Question 14

Anthracyclines

Answer 14

Cardio toxic

Question 15

Mitoxantrone

Answer 15

Semisynthetic anthracyclines

Question 16

Actinomycin D

Answer 16

Inhibit RNA synthesis

Question 17

Bleomycin

Answer 17

Breaks DNA

Question 18

Mitomycin

Answer 18

Cross links DNA

Question 19

Plan alkaloid from yew trees

Answer 19

Taxanes: microtubule poisons

Taxol
Docetaxel

Question 20

Ixabepilone

Answer 20

Works like taxanes. Derived from myxobacterium

Question 21

Plant alkaloid from periwinkles

Answer 21

Vinca alkaloids: neurotoxic!!!!!
Vincristine
Vinoblastine

Question 22

Folfiri

Answer 22

Folinic acid
Fluoro-uracil
Irinotecan

Question 23

Fluoro-uracil

Answer 23

Nucleotide synthesis inhibitors

Gastrointestinal toxicity

Question 24

ATRA

Answer 24

Treat APL. From a Chinese folk remedy

Question 25

Tamoxifen

Answer 25

Estrogen antagonist

Question 26

Exemestane

Answer 26

Mimics androgens

Question 27

Fulvestrant

Answer 27

Down regulates estrogen receptors

Question 28

Triptorelin

Answer 28

Suppress testosterone production

Question 29

Bicalutamide

Answer 29

Testosterone antagonist

Question 30

Glucocorticoid

Answer 30

White blood cell suppressive

Question 31

Schedule dependent drugs

Answer 31

Affect only one phase of cell cycle

Question 32

Schedule independent drugs

Answer 32

Cause long lasting chemical modifications. Cell death when they attempt division

Question 33

Drugs that affect S phase

Answer 33

Daunomycin. Ara-c

Question 34

Drugs that affect G1/M

Answer 34

Taxol