final Flashcards

1
Q

Clomiphene Citrate

A

Infertility
one year after failed trying
drug dependent
multiple birth
hot flash

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2
Q

Magnesium sulfate

A

Tocolytics - inhibit labor

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3
Q

Oxytocin

A

Induce labor
Stop postpartum hemorrhage

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4
Q

Metclopramide

A

Induce lactation

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5
Q

Estrogen

A

replacement
safe for osteoporosis
clots, dementia, antibiotic/anti-seizure meds decrease

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6
Q

Progestin

A

inhibit ovulation, amenorrhea
clots

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7
Q

Testosterone

A

Endometriosis
Fibrocystic breast

reproductive effects

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8
Q

Slidenafil

A

20-26m onset
ED
HA, cardiac conditions, Nitrate

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9
Q

Alprostadil

A

immediate onset

Burning/fibrosis

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10
Q

Finasteride

A

6-12mo onset
BPH

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11
Q

Tamsulosin

A

Immediate onset relaxation of prostate
BPH

Orthohypo

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12
Q

Epoetin Alpfa

A

Hematopoietic stimulation
RBC production
Need iron + V C
NO HBG <12
MI HTN

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13
Q

Filgrastim

A

Stim bone marrow

Bone paine

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14
Q

Interferon Alfa 2b

A

Immune stimulation

hematologic, autoimmune/ fatal infection

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15
Q

Aldesleukin

A

Immune stimulation
increase T cells

anaphylaxis, severe hypotension

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16
Q

Methotrexate/Mycophenolate

A

Immune suppression

infection, maligancy, pregnancy

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17
Q

Cyclosporine

A

immune suppressant
anti-rejection

HTN, nephrotoxic, infection, cancer

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18
Q

Adalimumab

A

suppress immune, decrease inflammation

pulmonary edema, fluid retention

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19
Q

Abatacept

A

immune suppressant
prevent cytokines

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20
Q

Acetaminophen

A

fever and pain

Liver failure 4g dose, acetylcystine antidote

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21
Q

Aspirin

A

pain/antiplatelet

GI bleed, hold 1wk pre/post op, give with food

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22
Q

NSAIDs

A

Meloxicam, Ibuprofen, Celecoxib, Indomethacin

GI/MI

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23
Q

Colchicine

A

GOUT
decrease crystal

Hepatotoxic

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24
Q

Allopurinol

A

GOUT
reduce acid

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25
Prednisone
Corticosteroid broad spectrum hyperglycemia, fluid retention, no live vaccine, taper off dose
26
Levothyroxine
Hypothyroid increase metabolic rate hyperthyroid, AM on empty stomach, 0.5-4.2mc
27
PTU
Hyperthyroid liver failure, hypothyroid
28
Iodine solution
Hyperthyroid pre-op staining
29
Somatropin
Growth deficiency stim growth hyperglycemia, muscle pain, closed epiphysis
30
Desmopressin
Diabetes Insipidus Cardiac arrest, hyponatremia
31
Leuprolide
Precocious Puberty decrease testosterone
32
Octreotide
Acromegaly inhibit growth hormone Hyperglycemia
33
Alendronate
hypercalcemia bind to bone and block calcium release esophageal irritation/erosion, inability to sit upright for 30 minutes, full glass water
34
Hydrocortisone
Addison's disease hyperglycemia, HTN, vertigo, before 0900
35
Fludrocortisone
Addison's disease HTN, CHF, growth suppression, hyperglycemia, hypokalemia
36
Ketoconazole
Cushing's inhibit cortisol itchy, liver toxic, acidic liquid
37
Phenobarbitol
Seizure Barbituates Steven-Johnsons Suicidal ideation
38
Lorazepam
Seizure Benzodiazepine status epilepticus R depression
39
Gabapentin
Seizure/Nerve pain
40
Phenytoin
Seizure 10-20mcg Gingival hyperplasia IV tissue toxic
41
Carbamazepine
Epilepsy Aplastic anemia, Agranulocytosis
42
Valproate
Seizure Pancreatitis, Alt clot time, teratogenic
43
Acetazolamine
Seizure Diuretic action
44
Dantrolene
Spasm/Spasticity Fatal liver impairment
45
Morphine Sulfate
antitussive, HF, PE IV- 10-20 min 5ml/5min Naloxone reversal
46
Butorphanol
opioid agonist/antagonist pre-op/labor pain
47
Naloxone
opioid antagonist immediate withdrawal short half life
48
Lidocaine
topical most painful site increase systemic w epi
49
Isoflurane
inhaled general anesthetic !MH dantrolene OD
50
Propofol
IV GA Rapid induction, <1min allergy to soy, egg, preserves
51
Vecronium
Neuromuscular GA relax/intubate 3-5min, 25-40min
52
Midazolam
Benzo, GA Flumazenil antidote
53
Fentanyl
adjuvant med Naloxone
54
Ergotamine
migraine no antifungal/antibiotic
55
sumatriptan
migraine
56
Imipramine
Tricyclic Antidepressant block reuptake of norepi 2-6hr at HS more toxic
57
Fluoxetine/Venla
SSRI ocd, bulimia seratonin syndrome
58
Phenelzine
MAOI increases epi HTN crisis, no tyramine, no ssri
59
Bupropin
aytipical antidepressant CNS effects neuropsychiatric reaction when smoke cessation
60
Lithium
Bipolar metallic taste, hand tremor no diuretics
61
Haloperidol
first gen antipsychotic IV 10-15 with 1.5in IM Tardive dyskinesia, akathisia, dystonia, parkinsons, prolog QT
62
Clozapine
second gen antipsychotic increase death in dementia, hyperglycemia
63
Dextroamphetamine
ADHD misuse can cause sudden death or serious CV events
64
Methylphenidate
ADHD no TCA
65
Atomoxetine
ADHD low risk abuse, suicidal ideation
66
Guanfacine
ADHD Antihypertensive Gi/CV 2 weeks
67
Chlordiazepoxide
Benzo for recovery HTN crisis, hyperpyrexia, agitation
68
Methadone
Substance abuse prevent withdrawal
69
Naltrexone
Substance abuse reduce cravings
70
cyclophosphamide
cancer bladder toxicity (2L)
71
Cisplatin
Cancer watch for extravastation
72
Tamoxiphen
Cancer Decrease estrogen
73
Leucovorin
Cytoprotectant folic acid
74
Oprelvekin
cytoprotectant increase platelet
75
Gentamicin
Antibiotic Ototoxic, nephrotoxicity Narrow TI Avoid penicillin within hour pre/post administration
76
Meropenem
Antibiotic Ulcerative colitis IM with lidocaine
77
Cephalosporin
Antibiotic bleeding
78
Aztreonam
Antibiotic dilation --> muc--> aztreonam
79
Penicillin
Antibiotic Interstitial nephritis, hypersensitivity cardiac arrest
80
Fluoroquiniolone
Antibiotic tendinitis, photosensitive, QT prolonging
81
Erythromycin
Antibiotic hepatotoxic, PC, prolong QT warfarin +dig
82
Fluconzaole + Diltiazem
cardiac death
83
Clindamycin
Antibiotic fatal PC
84
Vancomycin
Antibiotic narrow TI, red man syndrome
85
Linezolid
Antibiotic short-term serotonin syndrome bone marrow suppressant
86
Chloramphenicol
Antibiotic blood dyscrasia (aplastic anemia)
87
Sulfonamides
Antibiotic photosensitive, hypersensitive, Steven Johnson
88
Tetracyclines
Antibiotic remain upright 30 min renal failure for expired teeth discoloration harm bone growth
89
Phenazopyridine
Antiseptic orange color urine --> no UA renal failure 2< days
90
Rifampin
TB orange/staining
91
INH
TB liver toxic - VB6 50mg neuropathy
92
Pyrazinamide
TB high uric acid/joint pain
93
Ethambutol
TB Optic neuritis
94
Famciclovir Acyclovir Valacyclovir
Herpes purpura (decrease platelet tinny red dots
95
Ganciclovir
Cytomegaloherpes bone marrow suppression BIRTH DEFECT
96
Oseltamivir
Flu 48hr of symptom
97
Ribavirin
RSV inhaled, EXTREME TERATOGENIC
98
Amphotericin B
Antifungal big infection cardiac death no dextrose no amino
99
Fluconazole
Antifungal hepatic necrosis
100
Echinocandin
Antifungal drug binds to albumin
101
-Quinn
Antimalarial malaria pre/post exposure
102
Amebicides
drinking will damage liver flush/sweating
103
Lindane
CNS toxicity --> seizure