Final 1A

Question 1

What disease presents with fever, jaundince, and intracranial calcifications?

Answer 1

Toxoplasmosis

Question 2

What disease presents with skin rash, encephalitis, chorioretinitis, and hepatosplenomegaly?

Answer 2

Toxoplasmosis

Question 3

What does TORCH stand for?

Answer 3

Toxoplasma
Other - Syphilis, Varicella, HIV, HBV
Rubella
Cytomegalovirus
Herpes

Question 4

What disease’s definitive host is the cat and can be transmitted from improper handling of cat litter?

Answer 4

Toxoplasmosis

Question 5

What disease can be congenitally passed from handling or ingesting contaminated meat?

Answer 5

Toxoplasmosis

Question 6

What can be diagnosed either by immunofluorescence assay or giemsa-stained tissue preps showing tachyzoites?

Answer 6

Toxoplasmosis

Question 7

Toxoplasmosis can be diagnosed by immunofluorescence assay for what antibody?

Answer 7

IgM

Question 8

What disease causes syphilitic osteochondritis and periostitis affecting bones causing saber shin and saddle-nose deformities?

Answer 8

Syphilis

Question 9

Most common cause of congenital infection in the U.S. (TORCH)?

Answer 9

Cytomegalovirus

Question 10

What TORCH diseases belong to the Herpes family?

Answer 10

Varicella-Zoster
Herpes
Cytomegalovirus

Question 11

What TORCH disease has acidophilic nuclear inclusions (aka cowdry bodies)?

Answer 11

Congenital Herpes

Question 12

What TORCH disease has multinucleated giant cells with prominent basophilic nuclear inclusions?

Answer 12

Cytomegalic Inclusion Disease

Question 13

What TORCH disease can an infected woman trasmit the spirochete to her fetus after the 3rd month of pregnancy?

Answer 13

Congenital Syphilis

Question 14

What is syphilis?

Answer 14

a spirochete disease

Question 15

What are the different routes Cytomegalovirus can be transmitted?

Answer 15

Sexually
Blood transfusions
Organ transplants
Infant urination
Placenta
Birth canal
Mother's milk

Question 16

What is the most common congenital heart defect seen in congenital rubella syndrome?

Answer 16

Patent Ductus Arteriosus (PDA)

Question 17

What are the major components of surfactant?

Answer 17

lecithin, sphingomyelin

Question 18

What are the pro-surfactant hormones?

Answer 18

Cortisol
Thyroxine
Prolactin

Question 19

What is the anti-surfactant hormone?

Answer 19

Insulin

Question 20

What is DES?

Answer 20

Diethylstilbesterol

Question 21

What is another name for DES?

Answer 21

morning after pill

Question 22

What does DES cause?

Answer 22

cervical hood
T-shaped uterus
infertility
premature labor
associated with clear cell adenocarcinoma of the vagina

Question 23

What drugs can cause auditory nerve toxicity leading to deafness?

Answer 23

Aminoglycoside Antibiotics

such as: Streptomycin, Amikacin, Tobramycin

Question 24

What are the complications of using tetracycline in pregnancy?

Answer 24

permanently stained yellow teeth and hypoplasia of enamel

Question 25

Another name for Trisomy 21, 18, and 13?

Answer 25

21- Down syndrome 18 - Patau Syndrome 13 - Edward Syndrome

Question 26

What is the genetics of Cri Du Chat Syndrome?

Answer 26

deletion of short arm of chromosome 5

Question 27

What do infants have with Cri Du Chat Syndrome?

Answer 27

``` meow-like cry mental retardation microcephaly short fingers depressed nasal bridge round face cleft palates gut defects ```

Question 28

Deficiency in what vitamin is associated in neural tube defects?

Answer 28

folic acid

Question 29

General features of anencephaly?

Answer 29

absence of all or part of brain | more common in females

Question 30

Anencephaly an anterior or posterior neural tube defect?

Answer 30

anterior

Question 31

What is Area Cerebrovasculosa?

Answer 31

highly vascularized, poorly differentiated neural tissue

Question 32

Mildest form of Spina Bifida?

Answer 32

Spina Bifida Occulta

Question 33

What is Spina Bifida Occulta?

Answer 33

single vertebra fail to fuse, does not protrude, neural tube normal

Question 34

Name 4 types of Spina Bifida?

Answer 34

Spina Bifida Occulta Spina Bifida with meningocele Spina Bifida with meningocyelocele Spina Bifida with Rachischisis

Question 35

Worst Spina Bifida?

Answer 35

Spina Bifida with Rachischisis

Question 36

What’s different between meningoencephalocele and meningocele?

Answer 36

Meningocele - spinal fluid and meninges protrude, but no neural protrusion or defects Meningoencephalocele - everything protrudes and motor and lower nerve defects

Question 37

What classic karyotype is associated with 47 XXY

Answer 37

Klinefelter Syndrome

Question 38

Klinefelter syndrome best described as?

Answer 38

male hypogonadism

Question 39

Know that Klinefelter has a 50/50 chance of what?

Answer 39

maternal and paternal nondisjunction