final

Question 1

The goal of vaccination is best described by?

Answer 1

attempt to stimulate adaptive immune system to create memory

Question 2

antacids have a large source of?

Answer 2

aluminum

antiperspirants are 2nd

Question 3

to create memory killer t cells what must occur?

Answer 3

infected cell must present antigen on MHCI

Question 4

vaccine where organism is created and genes are removed that impair virulence and/or replicate describes?

Answer 4

recombinate vaccine

Question 5

Thimersol/mercury is in what vaccines?

Answer 5

influenza and DTAP

Question 6

what’s the function of an immunologic adjuvant?

Answer 6

increases immune response

Question 7

in the brain aluminum does what?

Answer 7

increases level of pro inflammatory cytokines

Question 8

what percentage of the world is infected by tb?

Answer 8

1/3

Question 9

what percentage actually develop tb?

Answer 9

5-10%

Question 10

how does tb create a problem for macrophages?

Answer 10

prevents phagosome from fusing with lysosome

Question 11

what bias is associated with allergy and asthma?

Answer 11

Th2

Question 12

self reactive antibodies against ACH receptors prevents ACH from binding producing muscle weakness is?

Answer 12

myasthenia gravis

Question 13

autoimmune dieases typically follow what?

Answer 13

infection

Question 14

healthy 6 month old has was Th bias?

Answer 14

Th1

Question 15

antibody associated with allergies?

Answer 15

IgE

Question 16

Tb macrophages die how?

Answer 16

necrosis

Question 17

in utero you have what Th bias?

Answer 17

Th2

Question 18

hypersensitivity associated with allergies?

Answer 18

type 1 (immediate)

Question 19

all forms of hypersensitivity require?

Answer 19

prior exposure to antigen

Question 20

type of hypersensitivity associated with poison ivy?

Answer 20

type 4

Question 21

deposition of antibody-antigen complexes causing INFLAMMATION is what type?

Answer 21

type 3

Question 22

why can the HIV-1 virus evade the immune system thus no vaccine?

Answer 22

high mutation rate

Question 23

most cancers are linked to viral infections?

Answer 23

false

Question 24

which immune cells are likely effective for cancer?

Answer 24

NK cells
(2nd macrophages)
(CTL’s are least effective)

Question 25

What is found on the surface of cancer cells that impairs the immune systems ability to destroy the aberrant cell?

Answer 25

PD-L1

Question 26

Pus is formed from?

Answer 26

neutrophils

Question 27

what helps surveillance against cancer?

Answer 27

innate | NK and macro

Question 28

what knocks out immune function by attacking helper T cells?

Answer 28

AIDS | CD4-->helper T cells

Question 29

Normal function of IgE is to act as a guidance system for which of the following cells, targeting its chemistry at larger parasites so they can be destroyed with minimal damage?

Answer 29

``` mast cells (then comes basophils from blood and then eosinophils from the bone marrow) eosinophils are "delayed" reaction to allergy ```

Question 30

what percentage of the US pop is affected by AI disease?

Answer 30

5-7.5%

Question 31

immune system attack on myelin basic protein in CNS is?

Answer 31

multiple sclerosis

Question 32

in order for an AI disease to develop there must be?

Answer 32

inflammation in the body

Question 33

In order to create memory helper T cells what must occur?

Answer 33

antigen presenting cell must present the antigen on MHC2

Question 34

what is an attenuate vaccine?

Answer 34

live organisms whose virulence is weakened

Question 35

DNA has been extracted from pathogen and used to make vaccine?

Answer 35

DNA vaccine

Question 36

what causes sepsis?

Answer 36

overreaction to widespread inflammatory response

Question 37

breakdown in B and T cell tolerance?

Answer 37

lupus

Question 38

breakdown of myelin in PNS?

Answer 38

Guillian-barre

Question 39

what hypersensitivity is associated with T cells?

Answer 39

type 4

Question 40

AB mediated IgM and/or IgG is what type?

Answer 40

type 2

Question 41

what percent of human cancers are linked to viral infections?

Answer 41

15-20%

Question 42

Memory B and T cells can be produced efficiently even when no immune system cells have been infected by the attacker?

Answer 42

TRUE

Question 43

anti-inflammatory cholinergic response is from?

Answer 43

the vagus nerve

Question 44

in order to create memory B cells what must occur?

Answer 44

antigen coming to a secondary lymph organ via lymph or blood

Question 45

aluminum induces a?

Answer 45

Th2 biased syndrome

Question 46

Allergies are caused by?

Answer 46

overproduction of IgE AB

Question 47

name the types of hypersensitivity..

Answer 47

type 1- allergies type 2- AB mediated IgM/IgG type 3- immune complex (INFLAMMATION) IgM/IgG type 4- cell mediated T-cells (poison ivy)