Final Flashcards
(52 cards)
Primary
Secondary
Tertiary
Attached to 1 carbon
Attached to 2 carbons
Attached to 3 carbons
Amine
Amide
NH2
O
||
C-N. Peptide bond
Amine salts
Ionic, used in meds, soluble on bodily fluids
Alkaloids
Caffeine, morphine, nicotine
Amidation
Formation of an amide
Amides in medicine
Acetaminophen
Amides: acid hydrolysis
Base hydrolysis
Produces carboxylic acid and ammonium salt
Amine or ammonium
Amino acids
20-all ionized in the body
Glycine, alanine, valine
Ser thr tyrosine
Polar neutral
Polar acidic
O
||
C-O or COO-
Polar basic
R= NH3+
His, lis, arg
What determines tertiary structure?
R-group
Sucrose
Sucrase
Products
Substrate
Enzyme
Glucose and fructose
Neurotransmiters
Contain N atoms as amines and alkyl ammonium atoms
Acetylcholine
Linked to Alzheimer’s, may decrease by 90%
Catecholamines
Dopamine, norepinephrine, epinephrine synthesized from tyrosine
Dopamine
Produced in nerve cells of midbrain
Act as natural stimulant to give energy and feelings of enjoyment
Norepinephrine and epinephrine
Hormonal Neurotransmitters
Serotonin
Relaxation, synthesized from tryptophan
Low levels associated with depression, anxiety
Histamine
Nerve cells in hypothalamus
From amino acid histidine
Produces allergic reaction
Glutamate
Most abundant neurotransmitter in NS
Too much in spinal cord causes degeneration of nerve cells (Lou Gerhigs)
GABA
Most common inhibitory neurotransmitter in brain
Primary structure of proteins
Sequence of amino acids
Secondary structure of proteins: alpha helix
Coiled shape held together by hydrogen bonds