Final Flashcards

(52 cards)

0
Q

Primary
Secondary
Tertiary

A

Attached to 1 carbon
Attached to 2 carbons
Attached to 3 carbons

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1
Q

Amine

Amide

A

NH2

O
||
C-N. Peptide bond

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2
Q

Amine salts

A

Ionic, used in meds, soluble on bodily fluids

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3
Q

Alkaloids

A

Caffeine, morphine, nicotine

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4
Q

Amidation

A

Formation of an amide

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5
Q

Amides in medicine

A

Acetaminophen

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6
Q

Amides: acid hydrolysis

Base hydrolysis

A

Produces carboxylic acid and ammonium salt

Amine or ammonium

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7
Q

Amino acids

A

20-all ionized in the body

Glycine, alanine, valine

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8
Q

Ser thr tyrosine

A

Polar neutral

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9
Q

Polar acidic

A

O
||
C-O or COO-

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10
Q

Polar basic

A

R= NH3+

His, lis, arg

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11
Q

What determines tertiary structure?

A

R-group

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12
Q

Sucrose

Sucrase
Products

A

Substrate

Enzyme
Glucose and fructose

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13
Q

Neurotransmiters

A

Contain N atoms as amines and alkyl ammonium atoms

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14
Q

Acetylcholine

A

Linked to Alzheimer’s, may decrease by 90%

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15
Q

Catecholamines

A

Dopamine, norepinephrine, epinephrine synthesized from tyrosine

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16
Q

Dopamine

A

Produced in nerve cells of midbrain

Act as natural stimulant to give energy and feelings of enjoyment

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17
Q

Norepinephrine and epinephrine

A

Hormonal Neurotransmitters

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18
Q

Serotonin

A

Relaxation, synthesized from tryptophan

Low levels associated with depression, anxiety

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19
Q

Histamine

A

Nerve cells in hypothalamus
From amino acid histidine

Produces allergic reaction

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20
Q

Glutamate

A

Most abundant neurotransmitter in NS

Too much in spinal cord causes degeneration of nerve cells (Lou Gerhigs)

21
Q

GABA

A

Most common inhibitory neurotransmitter in brain

22
Q

Primary structure of proteins

A

Sequence of amino acids

23
Q

Secondary structure of proteins: alpha helix

A

Coiled shape held together by hydrogen bonds

24
Secondary structure of proteins: beta-pleated sheet
Amino acid proline causes a bend in the polypeptide chain
25
Secondary structure of proteins: triple helix
3 alpha helix chains woven together Found in collagen, connective tissue, skin, tendons, cartilage
26
Tertiary structure of proteins
Specific 3D shape
27
Enzymes
Most active at 37 Celsius, pH 7.4
28
Water soluble vitamins
B1, B2, B3, B5, B6, folic acid, vitamin c (ascorbic acid) B12, biotin,
29
Beri beri
B1, thiamin deficiency
30
Fat soluble vitamins
A,D, E and K | Soluble in lipids not water
31
Catabolic Anabolic
Breaks down--produces energy Synthesizes--uses energy
32
Stages of catabolic reactions
Stage 1: digestion and hydrolysis Stage 2: degradation- glycolysis (forms 2 pyruvates) Stage 3: oxidation
33
ATP-ADP-AMP
Releases 7.3 kcal with each breakdown
34
Dehydronase enzymes
NAD+ forms c=o bond FAD forms c=c bond
35
CoA (coenzyme a)
Transfers acetyl groups
36
Citric acid cycle: reaction 1
Formation of citrate (tertiary alcohol)
37
Citric acid cycle: reaction 2
Formation of isocitrate (secondary alcohol) tertiary alcohols can't be oxidized
38
Citric acid cycle: reaction 3
Produces CO2, reduces NAD+ to NADH (3 atps)
39
Citric acid cycle: reaction 4
Reduce NAD+ to NADH, produces CO2
40
Citric acid cycle: reaction 5
Forms GTP Which is ATP
41
Citric acid cycle: reaction 6
Reduce FAD to FADH2
42
Citric Acid cycle: reaction 7
Formation of malate
43
Citric acid cycle: reaction 8
NAD+ to NADH
44
Lipid metabolism
Glycerol is metabolized in the liver via beta oxidation
45
Stage 1 catabolism: digestion and hydrolysis
Salivary amylase, pancreatic amylase
46
Stage 2 catabolism: degradation
Glycolysis- breakdown of glucose to 2 pyruvate molecules
47
Stage 3 catabolism: oxidation
Aerobic- Citric acid cycle Anaerobic- cori cycle
48
Glycogen
1 day storage of glucose
49
Glycogenesis
Formation of glycogen
50
Glycogenolysis
Breakdown of glycogen to glucose
51
Gluconeogensis
Breakdown of non carbohydrate sources to form glucose