Final Flashcards

(58 cards)

1
Q

Short segment of DNA that determines rate a protein will be synth?

A

Enhancer

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2
Q

Reticular Activation SX

A

Arousal, up and out

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3
Q

HPA axis

A

hypothalamic–pituitary–adrenal axis- stress

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4
Q

Parietal Lobe

A

Hemispatial/ 3D

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5
Q

Radialglia

A

House keepers

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6
Q

Microglia

A

respond to injury/ phags

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7
Q

Endothelial cells

A

BBB

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8
Q

Biologists who use drugs to manipulate brain and behavior of subjects

A

Psychopharmacologists

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9
Q

CSF

A

Bouys the brain, protective, connects the ventricular sx

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10
Q

How to identify and differentiate brain regions

A

chemical production or composition, types of cells, function

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11
Q

Astroglia

A

Regulate the outer environment, anchors, support

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12
Q

Evolution—->

A

Genes + experience= O O+enviro= BEHAVIOUR

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13
Q

Tectum

A

Midbrain, auditory and visual reflexes. Superior colliculus and inferior

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14
Q

Tegmentum

A

substantia nigra- mvmt

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15
Q

COGNITIVE NEUROSCIENCE

A

MRI, neural mechanisms of the human cognition, largely through the use of functional brain imaging

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16
Q

Synaptic transmission

A

signaling molecules called neurotransmitters are released by a neuron (slower than AP)

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17
Q

Temporal summation

A

synaptic events must occur closely enough in time to interact with one another

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18
Q

Leukodystrophies

A

genetic abnormalities myelin sheath

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19
Q

Subthreshold depolarization

A

potassium exiting exceeds sodium inflowing

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20
Q

MAO, AChE and SERT

A

Terminate synaptic signals

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21
Q

Autoreceptor

A

found on the presynaptic membrane

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22
Q

Medulla

A

breathing, swallowing and heart rate.

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23
Q

Hypothalmus

A

feeding, fleeing, fighting and Effing

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24
Q

Excitatory Ions

A

Sodium and Calcium (salty almonds)

25
Inhibitory
Potassium and Chloride (no one wants to eat a banana after its been in a pool)
26
Post Central gyrus
Parietal Lobe- for touch
27
Phases of AP
Rising, Falling, Relative Refractory/ hyperpolarization
28
Biogenic amine NTs:
dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline)—and histamine and serotonin
29
AA NTs
(EAA): L-Glutamate. (IAA): GABA
30
Cerebellum
Motor coordination
31
5 stages of ST
synth, prep for release, release, signal, termination
32
Temporal Lobe
auditory, smelling, visual, memory
33
Metatrophic
Mediates synaptic signals, Involves an enzyme, signalling cascade, slow, long lasting, conformational change
34
Ionic
Ion Channel, fast, short lived, 4 or 5 protein
35
Dopamine
``` Associated with mood Control of voluntary movement Reward mechanism in the brain Excessive amount=Schizophrenia Too little=Parkinson’s ```
36
BBB
- finely tuned electrochemical organ - can be severely destroyed by the introduction of certain chemicals - mechanism stops the passage of toxins from the blood into the brain - cells f the brain are tightly packed so toxins can’t flow through creating a barrier - many CNS disorders are associated with damage in the BBB
37
Agonist
produce stronger msgs/ more to promote ST
38
Antagonist
produce smaller/fewer/ inhibit ST
39
Alcohol
depressant, agonizes GABA and antagonizes Glutamate synapses
40
Caffeine
stimulant, most commonly used
41
Nicotine
Longest effects, stimulant
42
Marijuana
THC agonizes Anadamide
43
X-Ray
cheapest, shining light thru a body part
44
Contrast X-Ray
cerebral angiography, radio opaque dye, good for finding brain annerisms
45
CT/ CAT
shoots many x rays, many pictures, good for finding brain in normalities
46
MRI
higher resolution than CAT. measurements of waves from Hydrogen atoms, when placed in a magnetic field. expensive/ special training
47
PET
Images of brain activity, glucose, RYG, deeper than MEG
48
EEG
Gross electrical activity with electrodes
49
Why are some drugs legal and some not?
addictiveness, performance impairmants, adverse effects (all not always true)
50
Synthesis (Agonist vs Antagonist)
Agonist- enhance synth (ex- L-Dopa Park)/ Antag-block or reduce synth (ex-AMPT in schiz AMPT antag Dopemine)
51
Storage (Agonist vs Antagonist)
Agonists- NO/ Antag- block or reduce vesicles
52
Release (Agonist vs Antagonist)
Agonists- promote release of NTs (ex latrotoxin)/ antagonist- blocks release of NTs (botulism)
53
Signalling (Agonist vs Antagonist)
Agonists- activate NT receptors and/or enhance sensitivity Antag- block or reduce activation
54
Termination (Agonist vs Antagonist)
Agonist- SSRI Antagonist-
55
Sterotaxic surgery
gets coordinates in the brain, can insert an electrode
56
Pharmacokinetics
dosage response curves
57
MEG
so surface. measures changes in magnetic fields
58
FMRI
detects changes in blood flow/ oxygen levels