Final Flashcards

(70 cards)

1
Q

Most common estrogen component in hormonal birth control:

A

Ethinyl estradiol

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2
Q

Who makes the guidelines for contraception?

A

CDC

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3
Q

What form of estrogen is used after menopause?

A

estradiol valerate

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4
Q

What does HB2879 say?

A

That a pharmacist may prescribe and dispense hormonal birth control to anyone over age 18 w/o evidence of a prior prescription or someone under age 18 with evidence of a prior prescription.

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5
Q

What does a pharmacist have to so in order to become certified to prescribe hormonal birth control?

A

Complete a training program approved by the board of pharmacy
Provide a self-screening tool to the patient
Refer the patient to their women’s health care practitioner.
Provide the patient with a record of their prescription.

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6
Q

Can a pharmacist prescribe hormonal birth control for a patient that they prescribed to three years ago if they have not visited a women’s health provider since then?

A

No. However, the patient may be tricky and go to the pharmacy across the street to get it prescribed.

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7
Q

Can insurance cover this birth control?

A

Yes.

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8
Q

What has to be ACPE accredited?

A

The pharmacist training must be ACPE accredited.

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9
Q

What is a difference between pharmacists and doctors prescribing to self and family members?

A

Doctors are recommended not to, while pharmacist are prohibited from prescribing to self and family members.

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10
Q

What subjects are covered in the pharmacists training program?

A
Foundation for women's health
Pharmacology
Therapeutics
Patient Self-Assement
Workflow
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11
Q

What contraception method is most widely used?

A

The pill, while male condom comes in second. The 1st line option, the IUD is only 10% of the contraception used.

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12
Q

Is the rate of VTE higher for birth control, during pregnancy, or during postpartum?

A

VTE risk is the highest postpartum, second-highest during pregnancy, and third-highest while on OC’s.

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13
Q

What percentage of pregnancies are unintended?

A

50%

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14
Q

What did the Direct Access Study do?

A
  • 2008
  • Used a validated self-assessment questionnaire
  • Collaborative practice agreement
  • It was determined that pharmacist could effectively screen women and provide birth control. Women and pharmacists were satisfied.
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15
Q

What laws do Colorado, Washington, and California have in place regarding pharmacists providing birth control?

A

Washington has a window sticker law. California and Colorado have a state protocol that is identical to Oregon’s protocol. New Mexico also has a state protocol, while Missouri and Tennessee have a CPA.

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16
Q

What is US MEC?

A

Medical Eligibility Criteria

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17
Q

What are the categories for eligibility for contraceptive use?

A
  1. No restrictions
  2. Benefits usually outweigh risks
  3. Risks usually outweigh benefits
  4. Unacceptable health risk if contraceptive is used
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18
Q

What has the self-assessment questionnaire shown?

A

That women are capable of assessing their own risk more than a provider. However, OTC status is not a good idea, as studies have to be done first.

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19
Q

What are the patient-care centered steps?

A
Collect
Assess
Plan 
Implement
Follow-up
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20
Q

How much medication can you give the patient?

A

Initially, 3 months worth. Then another 9 months. The more medication you can give the patient, the more adherent they will be.
For continuing ex’s, can do 12 months.

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21
Q

What important documents are needed?

A
Standard procedures algorithm
Self-Screening questionnaire
Rules and regulations
policies and procedures
Patient visit summary
US MEC
List of nearby clinics for referral
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22
Q

What steps are required in order to prescribe someone birth control as a pharmacist?

A
  1. Health and history screen
  2. Pregnancy screen (period w.i last 7 days, 6 month old baby w/ no periods, abstaining since last period, using a contraceptive method consistently and correctly, etc.)
  3. Medication screen (cabamezepine, phenytoin, phenobarbital, primidone, topiramate. NOT St. John’s wort)
  4. Blood pressure (<140/90)
  5. After-visit summary may be provided, or circle referral instead, where it will have you list the reason. Provide list of nearby clinics.
  6. Discuss initiation strategy for treatment/change in treatment (counsel on starting now, using backup for 7 days, SE of bleeding irregularities, adherence, follow-up)
  7. Discuss and provide referral or visit summary.

**Pharmacy has to retain a cope of AVS and questionnaire, and send a copy to the PCP if they have one. Will still collect a fee.

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23
Q

What are the necessary things to counsel on?

A
Take by mouth
At same time every day
Set up first pill back
Start ASAP and use backup if needed for 1 week.
Placebo week, or not
When follow-up is needed
Hormonal contraception does not protect against STI's
Some drug interactions
Adherence is very important
Have back-up method on hand (condoms)

Expect:
Common- breakthrough bleeding for about 3 months
Serious - blood clots (five people in 10,000)
If side effects don’t go away, there are alternate formulations

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24
Q

What types of patients should be referred to a women’s healthcare provider?

A

No insurance - refer to free clinic

Contraindications

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25
What do pharmacies need to have to for a pharmacist to prescribe hormonal contraceptives?
A pharmacist's NPI needs to be changed to a pharmacist clinician. Certify their pharmacists as providers with each insurance company Some have software to interface pharmacy systems with billing.
26
Do you bill pharmacy or medical coverage for prescribing birth control?
Medical coverage
27
What is antimicrobial stewardship?
It is a professional role in infectious control. They make sure that inappropriate prescribing is not going on to curb resistance.
28
What is the difference between bacteriostatic and bactericidal? Which is more important for getting the right dose?
Bacteriostatic stops growth, while bactericidal kills bacteria. Bactericidal is more important for getting the right dose.
29
What is important to ask about allergies?
What the reaction was it, and how long ago was it?
30
What are the "when in doubt" antibiotic counseling points?
May cause n/v/d and GI upset Drink with a full glass of water Complete full course of therapy despite feeling better Look for s/s of hives, rash, difficulty breathing, and other s/s of allergic reactions (hypersensitivity reaction causes allergy 2nd time)
31
What are the skin organisms?
Gram positive. | Either strep or staph. Penicillin will probably fail to treat skin infections.
32
What would you cover for when treating a bug in the gut?
Gram negative anaerobes
33
What normally causes UTI's?
E. coli
34
What bugs normally cause pneumonia?
Staph and strep
35
``` Gram positive bacteria: Stain - Periplasmic space - Cell wall thickness - Porin channels- Analogy - Examples - ```
``` Stain - Pink Periplasmic space - Small Cell wall thickness - Thick Porin channels- Mostly absent Analogy - Thick fence Examples - strep, staph, enterococcus Thick peptidoglycan layer ```
36
``` Gram negative bacteria: Stain - Periplasmic space - Cell wall thickness - Porin channels- Analogy - Examples - ```
``` Stain - purple Periplasmic space - big Cell wall thickness - thin Porin channels- common Analogy - kevlar vest Examples - pseudomonas Thin peptidoglycan layer ```
37
Which type of bacteria is harder to kill?
Gram negative bacteria
38
What are ways of developing resistance for the bacteria?
``` Deactivate drug through beta lactamases Have active efflux channels Change binding sites Make the cell wall impenetrable Can change metabolic pathway despite what antibiotics are doing ```
39
MOA - Beta lactams
Inhibit cell wall synthesis
40
What generation of beta-lactams will treat MRSA? Pseudomonas?
``` 5th gen (Ceftaroline) will treat MRSA 4th gen and Ceftazidime will treat pseudomonas ```
41
1st gen cephalosporins
PEcK | Proteus, E. coli, Klebsiella
42
2ns gen cephalosporins
HEN PEcK H. influenza, Enterobacter, Neissera Proteus, E. coli, Klebsiella
43
3rd gen cephalosporins
HEN PEcK CAMPS | Citrobacterm Acinetobacter, Morganella, Pseudomonas
44
4th gen cephalosporins
HEN PEcK CAMPS + Provendencia
45
5th gen cephalosporins
HEN PEcK CAMPS + MRSA
46
What will the Carbapenems cover?
Pseudomonas but not MRSA
47
What could you use if you had a penicillin allergy?
Aztreonam, a monobactam.
48
Cephalosporins are LAME
Do not have activity against Listeria, atypical, MRSA, Enterococci
49
Which beta lactic can you take if you have liver problems?
Ceftriaxone
50
Which two cephalosporins cover pseudomonas?
Cefepime and ceftazadine
51
Which cephalosporin has activity against MRSA?
Ceftaroline
52
What antibiotics inhibit 50s ribosomal protein synthesis?
Macrolides Clindamycin Linezolid
53
What antibiotics inhibit the 30S ribosomal protein synthesis?
Aminoglycosides | Tetracycline
54
What inhibits DNA topoisomerase IV and DNA gyrase?
Floroquinolones
55
What antibiotics inhibit the folic acid pathway?
SMX/TMP
56
What antibiotics use strand breakage to inhibit protein synthesis?
Metronidazole
57
What inhibits cell synthesis? (D-Ala D-Ala)?
Nitrofurantoin | Vancomycin (D-Ala D-Ala)
58
Which antibiotics do you get photosensitivity from?
Floroquinolones SMX/TMP Tetracycline
59
Which antibiotic has the greatest risk of C. dif?
Clindamycin
60
Which antibiotic is red man syndrome associated with?
Vancomycin
61
Which antibiotics have to be monitored carefully due high risk of nephrotoxicity and ototoxicity?
Aminoglycosides
62
What is the DOC for C. dif infection?
Metronidazole
63
Which drugs have Q-T prolongation risks?
macrolides | floroquinolones
64
Which drug has a black box warning for colitis?
Clindamycin
65
What does vancomycin treat?
C dif in the PO form, not IV
66
What drug do you have to be cautious with serotonin-increasing agents?
Linezolid
67
What drugs cover pseudomonas?
``` Cefepime, ceftzadime ciprofloxacin, levofloxacin Imipenem, dirpenem, meropenem Aztreonam Aminoglycosides ```
68
What drugs cover atypical?
Macrolides Doxycycline Fluoroquinolones
69
What drugs cover anaerobes?
``` Metronidazole Piperacillin/Tazobactam Carbapenems Clindamycin Ampicillin/Sulfbactam Augmentin ```
70
What drugs cover MRSA?
``` CLindamycin SMX/TMP Tetracyclines Linezolid Vancomycin Daptomycin Telavancin Oritavancin Dalbavancin Ceftaroline ```