Final Flashcards
(179 cards)
What is the most common secretory diarrhea we see clinically?
Diarrhea caused by cholera or cholera-like toxins including heat-labeled toxin of E. Coli
Where are the majors sites of endogenous enzymatic digestion?
- Mouth
- Stomach
- Cranial duodenum
- Small intestinal brush border
The total daily amount of fluid entering the gut roughly equals the animal’s _______ volume.
ECF
About ____% of water that goes into the gut is absorbed before excretion.
99
How do crypt cells work?
As they undergo division, they take in NaCl from the interstitium, then the Na is recycled back into the ECF leaving a net negative electric charge inside cell causing Cl to diffuse out of dell into the intestinal lumen.
How do villus cell work?
They pump NA out of their ICF into the interstitium which causes a negative charge within the cell promoting the diffusion of luminal Na into the cell. Cl enters the cell as well in exchange for HCO3…water follows the ions from bicarbonate into the lumen.
What can cause maldigestion diarrhea?
- Poor chewing/mixing
- Poor digestive enzyme
- Poor acid production
What can cause malabsorption diarrhea?
- Loss of surface area of the gut
2. Thickening of the gut wall
What is exudative diarrhea
Result of inflammatory processes affecting the bowel where there is some loss of mucosal integrity leading to leakage of protein, plasma or blood into the guy lumen, or abnormal build up of pressure and protein in the tissue.
What type of diarrhea is the most severe?
Exudative
If there is an increase in peristalsis with a decrease in intestinal transport time, how does this contribute to diarrhea?
It can decrease the time for digestion and absorption to take place
If there is a decrease in peristalsis or mixing motility decreases contact with digestive/absorptive areas, how can this contribute to diarrhea?
It can promote bacterial overgrowth and fermentation leading to inflammation or the generation of secretagogues or osmotic earth compounds.
Which types of diarrhea involve direct tissue damage?
Malabsorption/maldigestion diarrhea and exudative diarrhea
Which type/types of diarrhea do not cause direct tissue damage?
Secretory
Syncope
Sudden, transient loss of consciousness resulting in collapse with spontaneous recovery caused by transient global cerebral hypoxia
How soon does loss of consciousness occur once blood flow stops?
10 seconds
What are some causes of cardiac syncope?
- Arrhythmias
- Obstruction to flow
- Low output
- Cyanotic heart disease
- Tamponade
What are some causes of neurologic syncope?
Increased intracranial pressure reducing cerebral perfusion
What are some causes of Metabolic syncope?
- Abrupt decrease in oxygen delivery
2. Abrupt decrease in nutrient delivery (glucose
What are some causes of tussle/cough syncope?
- Reduced venous return
2. Stimulation of vagal efferents producing bradycardia and vasodilation
What are causes of autonomic dysfunction syncope?
Neurocardiogenic
Bradyarrhythmias
6-8 second pause in hearts electrical activity
Tachyarrhythmias
Heart rate greater than 300bpm for more than 6-8 seconds
What types of bradyarrhythmias can cause syncope?
- High grade AV node block
- Sick sinus syndrome
- Atrial standstill