final Flashcards

1
Q

Attenuated Vaccines

A
Live bacteria, in-tact viruses
 Attenuated or modified to remove
pathogenicity
 Strong immune response, boosters
rarely needed
 Mumps, measels
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2
Q

Inactive Vaccines

A
Inactive
 Dead cells or fragmented viruses
 Weaker response – boosters
needed
 Hepatitis B, Polio
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3
Q

Toxoid Vaccines

A

Toxoid
 Vaccine directed at Exotoxins
 Very weak, boosters needed
 Tetanus, Diphtheria

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4
Q

Recombinant Vaccines

A
Recombinant
 Genetic engineering modifies
pathogen for vaccine
 Variable strengths
 HPV
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5
Q

Combination Vaccines

A

Combination
 Several vaccines mixed into 1 shot
 Variable strengths
 DTP, MMR

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6
Q

What is the study of the blood stream?

A

Serology- We use it to detect infections in the blood by looking for antigens(pathogens) or antibodies(certain antibodies will only be in the blood as an immune response from infections)

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7
Q

Monoclonal Antibodies

A

Monoclonal Antibodies are lab-produced. These are a single, pure
antibodies that recognizes a single antigen. Monoclonal antibodies
are utilized for many diagnostic tests
They are all clones of parent cell

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8
Q

Blood typing test is also known as what?

What is it?

A

Agglutination test/Blood Typing
 Monoclonal antibodies for A, B, and Rh proteins are utilized
 Agglutination or clumping determines blood type

This test looks like a plate with three oval’s labeled A, B, and Rh

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9
Q

If you have type A blood you naturally produce Anti-_ antibodies

A

Anti-B Antibodies

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10
Q

If you have type B blood you naturally produce Anti-_ antibodies

A

Anti-A Antibodies

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11
Q

If you have type O blood you naturally produce Anti-_ antibodies
If you have type AB blood you naturally produce Anti-_ antibodies

A

O blood- Anti-A antibodies and Anti-B Antibodies

AB blood- produces neither antibodies

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12
Q

What does ELISA stand for

A

Enzyme-Linked immuno-sorbent assay

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13
Q

ELISA

A

ELISA
 Very sensitive, accurate test for either antigens or
antibodies within the serum
 Enzyme-linked to antibody causes color change in positive
result
 CAN TEST FOR many antigens including HIV

This test looks like a huge number of cups each contains a specific antigen if the cups color changes its a positive result and you have that pathogen.

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14
Q

Direct Fluorescent Antibody Test

A

Direct Fluorescent Antibody Test
 Monoclonal Antibodies labelled with fluorescent dye
 Detect the dye using a fluorescent microscope
 Presence or absence of dye indicates presence or absence
of antigens in sample
 THIS TESTS FOR Tuberculosis

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15
Q

Point of care tests are also called what?

What is it?

A

Immunochromatographic assay

 ELISA test modified to run on a chromatography stick
 Quick, but not as sensitive as traditional ELISA
 TESTS FOR Pregnancy tests, strep throat tests

It looks like a paper like stick, you pee on the bottom, if both lines light up it indicates a positive

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16
Q

What chemical do pregnancy tests detect

A

Anti-HCG