Final Flashcards

(55 cards)

1
Q

Define osteoinduction.

A

New bone formation from differentiation of osteoprogenitor cells into osteoblasts

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2
Q

_________ is a cytokine that acts on progenitor cells to initiate osteoinduction.

A

BMP

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3
Q

T/F: BMP is higher in cortical bone than in cancellous bone.

A

True

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4
Q

T/F: Osteoconduction involves the production of bone.

A

False

Creates a scaffolding that conducts bone forming cells from the host

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5
Q

__________ is the formation of new bone from osteoprogenitor cells.

A

Osteogenesis

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6
Q

Which type of graft possesses osteogenic properties?

A

Autogenic grafts

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7
Q

During phase I of osteogenesis, transplanted cellular bone produces new __________.

A

Osteoid

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8
Q

What determines the quantity of bone that the graft will form?

A

Number of bone cells that survive phase I

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9
Q

Which phase of osteogenesis determines the quality of bone?

A

Phase II

Initial woven bone replaced by lamellar bone. BMP released by matrix as graft is resorbed

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10
Q

What is the gold standard of bone grafts?

A

Autograft

Most frequently used in OMFS, from same individual

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11
Q

__________ are osteoconductive and are harvested from human cadaver.

A

Allograft/homograft

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12
Q

___________ are transplanted between individuals fo different species.

A

Xenografts

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13
Q

T/F: Recombinate grafts are approved for children.

A

False

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14
Q

What are some common reasons for compromised would healing?

A

Medication, radiotherapy, infection, systemic disease

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15
Q

What are some diseases associated with bone healing problems?

A
  1. Medication related osteonecrosis of the Jaws (MRONJ)
  2. Osteo-radio-necrosis
  3. Osteomyelitis
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16
Q

What drugs are associated with MRONJ?

A
  1. Bisphosphonates
  2. Anti-resorptive agents
  3. Anti-angiogenic medications
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17
Q

T/F: Bisphosphonates inhibit osteoclasts and have a high affinity for calcium.

A

True

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18
Q

T/F: Patients with multiple myeloma take oral bisphosphonates.

A

False

IV

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19
Q

What are the parameters for diagnosis of MRONJ?

A
  1. Current or previous bisphosphonate treatment
  2. Exposed bone for more than eight weeks
  3. No hx of radiation to jaws
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20
Q

What are the three stages of osteo-radio-necrosis?

A
  1. Superficial (cortical bone)
  2. Localized (cortical and medullary bone)
  3. Diffuse (including inferior border)
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21
Q

_________ is an inflammatory process of bone marrow that involves cancellous and cortical bone with a tendency of progression.

A

Osteomyelitis

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22
Q

T/F: Osteomyelitis is more common in the mandible.

A

True

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23
Q

What is the antibiotic of choice for osteomyelitis?

24
Q

T/F: Dry socket can last for over 1 week.

A

False

If this long think osteomyelitis

25
What qualities should the temporary prosthesis have after grafting?
Non-load bearing | Limit wear
26
What are the advantages of distraction vs grafting vertical defects?
Minimal relapse, bigger movements possible, soft tissue comes with bone, low morbidity
27
Which of the grafting materials is ready more quickly than the others for sinus lift? Which is most expensive?
Autograft; BMP
28
How much bone can you achieve with indirect sinus lift?
4mm
29
T/F: A histological diagnosis is imperative prior to definitive treatment of pathology.
True
30
T/F: A true cyst has an epithelial lining.
True
31
What is the treatment of choice for cystic lesions?
Enucleation
32
What common cysts are often removed via enucleation?
Dentigerous and periapical cysts
33
How long will it take for bone to fill in an enucleation defect?
6-12 months
34
Which types of cyst require curettage after enucleation?
Aggressive cysts with common recurrence (OKC)
35
What is marsupialization?
Open a cystic lesion and keep it patent to an adjacent cavity. Cyst will shrink over time to allow for removal.
36
What is also known as the decompression technique?
Staged marsupialization and enucleation
37
T/F: Tumors in the maxilla have a worse prognosis.
True Often go longer undetected
38
T/F: Lesions must be removed with a 1 cm margin of uninvolved tissue.
True
39
What does it mean if a resection is segmental?
Full thickness all the way to inferior border removed
40
T/F: Bone-on-bone grinding of the condyle is a critical finding.
False
41
Why is posterior dentition important for proper jaw function?
Helps stabilize the joint
42
How should the clinical TMJ exam be done?
Multiple different movements should be done. Must pay attention to what hurts where when doing movements.
43
T/F: Patients with mechanical or inflammatory joint disease will benefit from TMJ surgery.
True
44
What is the typical sequence of surgical therapies for TMJ disorders?
Arthrocentesis -> arthroscopy -> open surgery
45
What is the most common indication for arthrocentesis?
Acute closed lock
46
Which part of the joint are you in during arthroscopy?
Superior envelope
47
___________ is an incision into the joint.
Arthrotomy
48
__________ is repair, revision, and/or reconstruction of joint tissue.
Arthroplasty
49
____________ is removal of the disk.
Meniscectomy/discectomy
50
T/F: Preauricular incision for open surgery is anterior to the ear.
True
51
T/F: If you remove the disk you must replace it with graft.
False
52
What is the most common graft for replacing the condyle?
Costochondral graft (rib)
53
T/F: Materials for total joint replacement can last a lifetime.
False 15 years is current estimate
54
What are the goals of TMJ reconstruction?
1. Restore and maintain jaw function 2. Restore and maintain facial symmetry 3. Long-term skeletal and occlusal stability Alleviate pain-secondary
55
T/F: Pain is often eliminated in total joint replacement.
False Decreased but not eliminated