Final Entry test Flashcards

Mode and Mech of action and Substance group pairing

1
Q

Benzylpenicillin - NA, K

Benzylpenicillin - procaine

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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2
Q

Benzylpenecilin - benzathine

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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3
Q

PHenoxymethyl - penicillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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4
Q

oxacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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5
Q

Cloxacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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6
Q

Dicoloxacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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7
Q

Flucloxacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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8
Q

Amoxicillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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9
Q

Ampicillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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10
Q

Ticarcillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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11
Q

Piperacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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12
Q

Clavulanic acid

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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13
Q

Sulbactam

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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14
Q

Tazobactam

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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15
Q

cephazoline

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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16
Q

Cephapirin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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17
Q

Cefadroxil

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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18
Q

Cephalexin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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19
Q

Cefuroxime

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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20
Q

Ceftiofur

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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21
Q

Cefovecin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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22
Q

Ceftriaxone

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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23
Q

Cefotaxime

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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24
Q

Cefoperazone

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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25
Cefquinone
Time dependent bactericidal | Inhibition of cell wall synthesis
26
Imipenem
Time dependent bactericidal | Inhibition of cell wall synthesis
27
Meropenem
Time dependent bactericidal | Inhibition of cell wall synthesis
28
Aztreonam
Time dependent bactericidal | Inhibition of cell wall synthesis
29
Tigemonam
Time dependent bactericidal | Inhibition of cell wall synthesis
30
Streptomycin
Concentration dependent bactericidal | Inhibition of protein synthesis (30s subunit), mistranslation
31
Neomycin
Concentration dependent bactericidal | Inhibition of protein synthesis (30s subunit), mistranslation
32
Paromomicin
Concentration dependent bactericidal | Inhibition of protein synthesis (30s subunit), mistranslation
33
Kanamicin
Concentration dependent bactericidal | Inhibition of protein synthesis (30s subunit), mistranslation
34
Gentamicin
Concentration dependent bactericidal | Inhibition of protein synthesis (30s subunit), mistranslation
35
Tobramycin
Concentration dependent bactericidal | Inhibition of protein synthesis (30s subunit), mistranslation
36
Amikacin
Concentration dependent bactericidal | Inhibition of protein synthesis (30s subunit), mistranslation
37
Apramycin
Concentration dependent bactericidal | Inhibition of protein synthesis (30s subunit), mistranslation
38
Spectinomycin
Bacteriostatic | Inhibition of protein synthesis (30s Subunit), mistranslation
39
Chlortetracycline
Bacteriostatic | Inhibition of protein synthesis (30s Subunit), mistranslation
40
Oxytetracycline
Bacteriostatic | Inhibition of protein synthesis (30s Subunit), mistranslation
41
tetracycline
Bacteriostatic | Inhibition of protein synthesis (30s Subunit), mistranslation
42
Doxycycline
Bacteriostatic | Inhibition of protein synthesis (30s Subunit), mistranslation
43
Minocycline
Bacteriostatic | Inhibition of protein synthesis (30s Subunit), mistranslation
44
Erythromycin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
45
Azithromycin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
46
Clarithromycin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
47
Spiramycin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
48
Tylosin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
49
Tylvalosin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
50
Tilmicosin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
51
Tulathromycin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
52
Gamithromycin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
53
Tildipirosin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
54
Lincomycin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
55
Clindamycin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
56
Tiamulin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
57
Valnemulin
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
58
Chloramphenicol
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
59
Florfenicol
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
60
Thiamphenicol
Bacteriostatic | Inhibition of protein synthesis (50s Subunit), mistranslation
61
Bacitracin
Concentration dependent bactericidal | act like cationic detergent
62
Polymyxin B
Concentration dependent bactericidal | act like cationic detergent
63
Polymyxin E = Colistin
Concentration dependent bactericidal | act like cationic detergent
64
Vancomycin
Time dependent bactericidal | Inhibition of cell wall synthesis
65
Teicoplanin
Time dependent bactericidal | Inhibition of cell wall synthesis
66
Rifampicin
Time dependent bactericidal | Inhibit bacterial DNA-dependent RNA polymerase
67
Mupirocin
Bactericidal | Inhibition of cell wall synthesis
68
Fosfomycin
Bactericidal | Inhibition of cell wall synthesis
69
Fusidic acid
Bacteriostatic | Inhibition of protein synthesis
70
Sulfadimidine
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
71
Sulfadiazine
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
72
Sulfachlorpyrazine
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
73
Sulfamethoxasole
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
74
Sulfadoxine
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
75
Sulfaquinoxaline
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
76
Sulfasalazine
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
77
Trimethoprim
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
78
Baquiloprim
Separately bacteriostatic and in combination time dependent bactericidal Inhibition of folic acid synthesis
79
Nalidix acid
Concentration dependent bactericidal | Inhibition of DNA synthesis
80
Flumequine
Concentration dependent bactericidal | Inhibition of DNA synthesis
81
Norfloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
82
Orbifloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
83
Ciprofloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
84
Enrofloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
85
Danofloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
86
Difloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
87
Marbofloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
88
levofloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
89
Sparfloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
90
Pradofloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
91
Moxifloxacin
Concentration dependent bactericidal | Inhibition of DNA synthesis
92
Nitrofurantoin
Bactericidal | Destroy the DNA of bacteria
93
Furazolidone
Bactericidal | Destroy the DNA of bacteria
94
Metronidazole
Concentration dependent bactericidal | Destroy the DNA of bacteria
95
Ronidazole
Concentration dependent bactericidal | Destroy the DNA of bacteria
96
Tinidazole
Concentration dependent bactericidal | Destroy the DNA of bacteria
97
B- lactam antibiotics Main groups
``` Penicillins B-lactamase-inhibitors Cephalosporins carbapenems monobactams ```
98
Benzylpenicillin - Na, K Benzylpenicillin - procaine Benzylpenicillin - benzathine Phenoxymethyl - penicillin
Narrow spectrum Penicillins Penicillins B-lactam antibiotics TDBC, Inhibit cell wall synth
99
Oxacillin cloxacillin dicloxacillin flucloxacillin
Penicillinase stable Penicillins penicillins B-lactam antibiotics TDBC, Inhibit cell wall synth
100
Amoxacillin | ampicillin
Broad spectrum pencilillins Penicillins B-lactam antibiotics TDBC, Inhibit cell wall synth
101
ticarcillin | piperacilin
Penicillins acting against pseudomonas spp penicillins B-lactam antibiotics TDBC, Inhibit cell wall synth
102
Clavulinic acid sulbactam tazobactam
B-lactamase inhibitors B-lactam antibiotics TDBC, Inhibit cell wall synth
103
Cephazolline cephaprirn cefadroxil cephalexin
Gen 1 Cephalosporins B-lactam antibiotics TDBC, Inhibit cell wall synth
104
Cefuroxime
Gen 2 Cephalosporins B-lactam antibiotics TDBC, Inhibit cell wall synth
105
``` Ceftiofur Cefovecin ceftriaxone cefotaxime Ceftazidime Cefoperazone ```
Gen 3 Cephalosporins B-actam antibiotics TDBC, Inhibit cell wall synth
106
Cefquinome
Gen 4 cephalosporins B-lactam antibiotics TDBC, Inhibit cell wall synth
107
Imipenem | Meropenem
Carbapenems B-lactam antibiotics TDBC, Inhibit cell wall synth
108
Azteronam | tigemonam
Monobactams B-lactam antibiotics TDBC, Inhibit cell wall synth
109
Streptomycin neomycin paromomicin kanamycin
Aminoglycosides | CDBC, Inhibit 30s
110
``` gentamycin tobramycin amikacin aparmycin spectinomycin ```
Aminoglycosides CDBC, Inhibit 30s Spectinomycin - bacteriostatic
111
Chlortetracycline Oxytetracycline Tetracycline
Short acting tetracyclines | BStatic, Inhibit 30s
112
Doxytetracycline | minocycline
Long acting tetracyclines | BStatic, Inhibit 30s
113
Erythromycin | azithromycin
Macrolides | Bstatic, inhibit 50s
114
clarithromycin Spiramycin Tylosin
Macrolides | Bstatic, inhibit 50s
115
tylvalosin tilmicosin tulathromycin
Macrolides | Bstatic, inhibit 50s
116
gamithromycin | tildipirosin
Macrolides | Bstatic, inhibit 50s
117
Lincomycin | clindaymcin
Lincosamides | Bstatic, inhibit 50s
118
Chloramphenicol Florfenicol Thiamphenicol
Phenicols | Bstatic, inhibit 50s
119
Bacitracin Polymyxin B Colistin - Polymyxin E
Polypeptide antibiotics Peptide Ab CDBC, cationic detergent
120
Vancomycin | Teicoplanin
Glycopeptide antibiotics Peptide Ab TDBC, inhibit cell wall synth
121
Rifampicin
Rifamycines | TDBC, inhibit bact DNA-dependent RNA polymerase
122
Mupirocin
Pseudomonic acid | BC, Inhibit cell wall synth
123
Fosfomycin
Phosphonic acid derivates | BC, inhibit cell wall synth
124
Fusidic acid
Fusidic acid | BStatic, inhibition of protein synthesis
125
Sulfadimidine | Sulfadiazine
Sulphonamides Separately Bstatic, combination TDBC Inhibit folic acid synthesis
126
Sulfadoxine Sulfaquinoxaline Sulfasalazine
Sulphonamides Separately Bstatic, combination TDBC Inhibit folic acid synthesis
127
Sulfachlorpyridazine Sulfachlorpyrazine Sulfamethoxasole
Sulphonamides Separately Bstatic, combination TDBC Inhibit folic acid synthesis
128
Trimethoprim | Baquiloprim
Diaminopyramidines Separately Bstatic, combination TDBC Inhibit folic acid synthesis
129
Nalidixic acid
Gen 1 Fluoroquinolones | CDBC, Inhibition of DNA Synthesis
130
Flumequine | Norfloxacin
Gen 2 Fluoroquinolones | CDBC, Inhibition of DNA Synthesis
131
Danofloxacin Difloxacin Marbofloxacin
Gen 2 Fluoroquinolones | CDBC, Inhibition of DNA Synthesis
132
Orbifloxacin Ciprofloxacin Enrofloxacin
Gen 2 Fluoroquinolones | CDBC, Inhibition of DNA Synthesis
133
Levofloxacin | Sparfloxacin
Gen 3 Fluoroquinolones | CDBC, Inhibition of DNA Synthesis
134
Pradofloxacin | Moxifloxacin
Gen 4 Fluoroquinolones | CDBC, Inhibition of DNA Synthesis
135
Nitrofuratoin | Furazolidone
Nitrofurans | Bactercidal, Destroy Bact DNA
136
Metronidazole Ronidazole Tinidazole
Nitroimidazoles | CDBC, Destroy Bact DNA