final exam Flashcards
(184 cards)
what type of cancer is processed meat linked to?
21% of bowel cancer
the meat forms N-nitroso compounds such as nitrosamines (which are potent
carcinogens) as they react during the processing, storage and/or cooking process
Are naturally sourced nitrates better than synthetic ones with respect to the “chemistry” of processed meat?
no
It is estimated that eating processed and red meats leads to a ____ % increase in bowel cancer.
21%
What is innate immunity?
Is the immunity we are born with, it includes barriers (skin), phagocytic cells, antimicrobial proteins, the inflammatory response, and natural killer cells.
What are the first barriers/lines of defense of the innate immune system?
skin and mucous membrane, temperature,
low pH and chemical mediators, inflammatory response
Neutrophils, macrophages and natural killer cells are all types of _______ blood cells.
white
What are interferons and how do they protect cells against viral attack?
infected cell produces infron proteins that exocytose from cell and enter another non infected cell and stimulates that cell to produce antiviral proteins to protect itself from infection
What does a Mast cell produce?
histamine
Describe the steps of an inflammatory response
mast cells signal WBC thats theres a problem
capillaries diolate (widen) and become leaky so neutrophils can exit and enter imfection
neutrophils digest bacteria and tissue repairs
What are the three key ingredients of pus?
dead white blood cells,
fluid leaked from capillaries and tissue debris
What can be found in lymph nodes?
Lymph nodes filter substances that travel through the lymphatic fluid, and they contain lymphocytes (white blood cells) that help the body fight infection and disease.
whats the function of the lymphatic sys?
to fight infection and return fluids to circulatory sys
What is the adaptive immune response? what are the 2 types?
activated only after exposure to pathogens
humoral response
cell mediated response
whats the humoral response
antibodies defend against infection in body fluids
whats the cell mediated response in adaptive imm?
the destruction of infected cells by cytotoxic T cells
What is an antigen?
any molecule that provokes imm resppnse
What is an antibody?
a protein dissolved in blood plasma that attaches to a specific kind of antigen and helps to counter its effects.
What do antibodies do?
Antibodies destroy bacteria and viruses, thereby preventing them from entering host cells.
where do B and T cells mature?
B-bone marrow
T-thymus
B cells are responsible for the __________ immune response and T cells for the _______ ___________immune response.
B- humoral
T- cell mediated
how many B and T cells do we have?
100,000
what types of cells do B cells produce after exposure? what are their jobs?
plasma cells- short lived, secrete antibodies to attack
memory cells- long lived, ready to be activated by a second exposure to the antigen.
The first exposure is called a __________ immune response. The next time you are exposed it is a_________ immune response.
primary
secondary
When a cell becomes infected, “self” proteins will bind to the antigen and present it on the surface of the cell. Once noticed by a helper T cell what will happen?
- It will make more copies of itself.
- It will produce signaling molecules to turn on B cells that will produce more antibodies and
- It will activate cytotoxic T cells to kill the infected cells.