Final Exam Flashcards

(726 cards)

1
Q

What is the priority in preoperative and postoperative care?

1) Pain management
2) Evidence of voiding
3) Safety
4) Education and assessing patient knowledge

A

3) Safety

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2
Q

Name 5 pre-operative activities that must be completed:

A

1) Make patient NPO
2) Ensure they have voided
3) Hold blood thinners
4) Blood type/screen
5) Assess patient knowledge and education
6) Witness and verify informed consent
7) History and physical (Head to toe)
8) CBC
9) EKG
10) Remove glasses, jewelry, contacts, hairpins
11) Vitals, height, weight
12) Any other diagnostic tests needed/ordered
13) skin prep with CHG and clippers
14) Antibiotic prophylaxis
15) Any other essential medications

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3
Q

Aside from informed consent issues, what is the most important thing to report, preoperatively, to the surgical team?

A

Any unexpected findings, baseline is key!

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4
Q

What are the 2 responsibilities of a nurse when it comes to informed consent before a procedure?

A

1) The nurse must witness and verify the informed consent
2) The nurse can only reinforce facts already provided to the patient about the procedure by the surgeon

- Note: only the surgeon can obtain consent and teach about the procedure

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5
Q

True or false: The nurse is responsible for obtaining patient consent, but not for teaching the patient about the procedure

A

False: The nurse is not responsible for obtaining consent for surgical procedures BUT it is correct that they are not responsible for teaching the patient about the surgery

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6
Q

In what two circumstances would a nurse need to urgently notify a surgeon in a situation about informed consent?

Why would they inform them?

A

1) If the patient is not adequatly informed (some or part of informed consent about the procedure is missing)
2) There is a discrepancy in surgical site for the procedure

Why: The nurse has a professional AND ethical duty to notify the surgeon

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7
Q

What medication should always be given and what kind of medications should awlays be held preoperatively?

1) Antibiotics; antihypertensives
2) Blood thinners; cardiac glycosides (i.e. Digoxin)
3) Beta-blockers; diuretics
4) Antibiotics: blood thinners

A

4) Antibiotics; blood thinners
- Antibiotics help prophylactically prevent infection and blood thinners are held due to high risk for hemorrhage/bleeding

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8
Q

What type of surgery is an alternative for those with religious or medical restrictions to blood transfusions?

A

Bloodless or minimally invasive surgery

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9
Q

True or false: Nurses must honor a patient’s request to have no blood transfusions during surgery, even in an emergency, based on religious views

A

True: All healthcare providers must honor an individual’s religous views when it comes to blood and blood products during

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10
Q

What are ways to honor a patient’s religious views while still providing them blood or replinishing their blood preoperatively, intraoperatively, and/or postoperatively?

A

1) Stimulate the patient’s own RBC production using erythropoetin alfa, iron, folic acid, vitamin B12, and vitamin C
2) Provide autologous transfusions (take blood from the patient prior in advance to then give back if needed during the surgery)
3) Cellsavers (collects blood lost from a patient during surgery and reinfuses it)

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11
Q

Going through the systems below, name one reason older adults are at greater risk for postoperative complications?

  • Skin
  • Renal/urinary
  • Nuerological
  • CV
  • Respiratory
  • Musculoskeletal
A

- Skin: more fragile, delayed healing
- Renal/urinary: decreased kidney function and less waste removal
- Neurological: impaired cognition, function, and sensory impairments
- CV: hypertension/hypotension
- Respiratory: Decreased lung capacity
- Musculoskeletal: more mobility disease like arithritis making positioning challenging

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12
Q

What are the three priorities postoperatively?

A

1) Safety - Airway is the main priority
2) Immediate assessment of VS and continuous monitoring (Q15minute vitals for first hour)
3) Pain assessment

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13
Q

What are the main vital signs we are concerned with postoperatively?

What do we typically watch for with blood pressure?

A

1) BP
2) RR
3) SaO2

BP: We watch for hypotension

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14
Q

Anaesthesia affects patients after a surgery, what should nurses be watching for?

A

1) Bradypnea (slow RR)
2) Hypotension
3) Fall risk
4) Urinary retention

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15
Q

What are six ways to enhance postoperative recovery?

A

1) Ambulate early/early mobility
2) Early intake
3) Mild analgesics
4) Manage nausea/vomiting
5) Discontinue IV fluids early
6) Continue education

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16
Q

There are many postoperative complications that can occur. Name two from each of the following systems:

  • Respiratory
  • CV
  • Nuero
  • Neuromuscular
  • GI
  • Renal
  • Skin
A

- Respiratory: atelectasis, pneumonia, pulmonary embolism, DVT
- CV: anemia, hypertension, hypotension, hypovolemia, sepsis
- Nuero: delirium, stroke
- Neuromuscular: hypo/hyperthermia, joint contractures
- GI: ulcers, bleeding, paralytic ileus
- Renal: acute kidney injury, urinary retention, UTI, electrolyte imbalances
- Skin: pressure injuries, skin rashes/contact dermititis, wound infection, wound dehisence, wound evisceration

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17
Q

What is the best way to identifty postoperative abnormalities?

A

Compare the patient to their preoperative assessment! What is their O2 sat, VS, Head-to-toe, and pain at now compared to preoperatively?

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18
Q

Taking action: what are ways to alleviate/prevent postoperative respiratory complciations?

A

1) HOB to 30 degrees (semi-fowler’s)
2) Provide supportive O2
3) Suction as needed
4) Nebulizers as needed

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19
Q

How often should vitals signs be monitored postoperatively for the first hour, next four hours, and next 24 hours?

A
  • Q5-15Minutes x 1 hour
  • Q1H x 4 hours
  • Q4H x 24 hours
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20
Q

Taking action: what are ways to alleviate/prevent postoperative body temperature complciations?

A
  • Provide a warming blanket
  • Use the bear hugger
  • Dentrolene sodium if malignant hyperthermia
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21
Q

Taking action: what are ways to alleviate/prevent postoperative pain?

A

1) Non-pharmacological methods (heat, ice, distraction)
2) Pharmacological (consider non-opioid for those with low RR)

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22
Q

What aspects should you consider when conducting a neurovascular assessment on a postoperative patient?

A

1) Capillary refill (< 3 seconds)
2) Temperature
3) Sensation
4) Movement
5) Color

  • Remember to compare bilaterally!!
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23
Q

What two indicators signal that a patient’s diet can be advanced after surgery?

A

1) Swallow ability (can swallow)
2) Passing flatus (indicated peristalsis is working)

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24
Q

What is a typical dietary advancement?

A

NPO -> Clear liquids -> Full liquids -> BRAT -> normal diet

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25
Malignant hyperthemia: what is it, signs and symptoms, who do you notify, treatment
**What is it:** an inherited disorder that can occur when exposed anesthetics **Signs and symptoms:** **1)** Tachycardia **2)** Decreased oxygen saturation **3)** Muscle rigidity of the jaw and/or chest **4)** Hypotension **5)** Elevated body temperature (late sign) **Notify:** Immediately notify surgeon and anasthesiologist **Treatment:** dantrolene sodium
26
What does the ICOUGH acronym stand for in pneumonia prevention?
**I:** Incentive spirometry 10x/hour every hour while awake **C:** Coughing and deep breathing Q1H while awake **O:** Oral care **U:** Understanding (by patient) **G:** Get up out of bed **H:** Head of bed at 30 degrees
27
How can delayed wound healing be prevented postoperatively?
**1)** Consume high protein meals **2)** Take vitamins A+C **3)** Take zinc
28
What is wound evisceration and what steps should a nurse take if it happens?
**1)** Call rapid response **2)** Have patient lay at 20 degree with knees bent **3)** Use a sterile dressing w/ saline to cover the organs **4)** Notify surgeon **- This is a medical emergency**
29
The family member of a patient is pressing the patient-controlled analgeisa, what is the nurses immediate action? 1) Confront the family member about pushing the button 2) Assess the continuous vital signs monitor 3) Check the analgeisa pump 4) Assess the patient
**4)** Assess the patient
30
A client with acute kidney injury (AKI) has a blood pressure of 76/55 mm Hg. The primary health care provider prescribed 1000 mL of normal saline to be infused over 1 hour to maintain perfusion. The client starts to develop shortness of breath. What is the nurse’s priority action? 1) Decrease the rate of the IV infusion. 2) Take the client’s pulse. 3) Calculate the mean arterial pressure (MAP). 4) Ask for insertion of a pulmonary artery catheter.
**1)** Decrease the rate of the IV infusion.
31
A patient is 2 days post-knee replacement surgery. The nurse notes the following: blood pressure 85/55 mmHg, urine output 15 mL/hr, dry mucous membranes, and increased confusion. 1) Infection 2) Hypovolemia 3) Pain related stress response 4) Pulmonary embolism
**2)** Hypovolemia
32
A 60-year-old patient recovering from thoracic surgery reports 8/10 chest pain and refuses to cough or take deep breaths because "it hurts too much." The nurse notes diminished breath sounds at the left lung base. What is the most appropriate initial nursing action? 1) Encourage use of an incentive spirometer 2) Notify respiratory therapy 3) Administer prescribed pain medication 4) Elevate the head of the bed
**3)** Administer prescribed pain medication
33
Which nursing action best promotes perfusion in a post-op patient? 1) Encourage incentive spirometry every hour 2) Keep legs elevated above the level of the heart 3) Increase IV fluid rate 4) Ambulate the patient as soon as tolerated
**4)** Ambulate the patient as soon as tolerated
34
When the post-anesthesia care unit (PACU) charge nurse notes vital signs on four postoperative clients the assessment of which client would be the priority? 1) Client with a pulse of 118 beats/min 2) Client with a blood pressure of 100/50 mm Hg 3) Client with a respiratory rate of 6 breaths/min 4) Client with a temperature of 96°F (35.6°C)
**3)** Client with a respiratory rate of 6 breaths/min
35
What is normal SaO2? 1) 94%+ 2) 93%+ 3) 95%+
3) 95%+
36
What is the normal range for PaO2? 1) 70-100 mmHg 2) 80-100 mmHg 3) 90-100 mmHg
2) 80-100 mmHg
37
What are primary prevention methods to improve gas exchange?
**1)** Infection control **2)** Smoking cessation **3)** Immunization
38
What are ways to prevent post-op gas exchange problems?
**1)** Incentive spirometry Q1H while awake **2)** Coughing and deep breathing Q1H (splinting) **3)** DVT prevention for PE -> sequential compression, early ambulation, anticoagulants
39
How often should incentive spirometry be preformed? 1) Q1H 2) Q2H 3) Q4H
**1)** Q1H while awake
40
In order to maintain proper ventilation, is it better to eat smaller, more frequent meals high in calories and protein, or is it better to eat larger, less frequent meals high in proteins and calories
It is better to eat smaller, more frequent meals higher in calories and proteins
41
Bronchodilators should be used: 1) Before meals 2) After meals 3) Partway through meals
**1)** Before meals to open airways to maintain proper ventilation while eating
42
When eating patients should be placed: 1) In semi-fowlers or tripod 2) In high-fowlers or tripod 3) In trundelenberg or tripod
**2)** In high fowler's or tripod to promote airway patency and ventilation
43
What should be done before meals to improve the taste of food: 1) Administer bronchodilators 2) Place in high-fowler's 3) Provide oral care
**3)** Provide oral care as it removes plaque, build up, and moistens the tongue - The other two should be done before meals, but do not improve the taste of food
44
True or false: COPD is a collection of lower airway disorders with airflow and gas exchange including emphysema and asthma
**False:** COPD does include emphysema and chronic bronchitis, not asthma
45
Describe emphysema:
It is a destructive problems of lung elastic tissue of alveoli that reduces its ability to recoil after stretching leading to hyperinflation
46
What is primary emphysema?
It is a decrease in enzyme alpha 1 antitrypsin, which normally protects against protease enzymes, found in non-smokers as an inherited disorder - Lack of AAT allows proteases to harm elastic tissue of the alveoli
47
What is secondary emphysema?
It is when cigarette smoking, air pollution, occupational exposure, or another respiratory tract infection in childhood triggers an inflammatory reaction promoting proteases to break down the elastin in alveoli
48
What are proteases? How does cigarette smoke cause issues related to proteases?
**1)** enzymes that eliminate particulates during breathing **2)** Cigarette smoke triggers high levels of proteases that damage the alveoli breaking down the elastin = less recoil causing collapsing and narrowing of the lungs reducing area for gas exchange
49
What does emphysema do to the diaphragm? 1) Hyperinflated lungs flatten the diaphragm, weakening it 2) Hyperinflated lungs cause diaphragm contraction, strengthening it 3) Hyperinflated lungs do not put pressure on the diaphragm, they only put pressure on the chest wall leaving breathing unchanged
**1)** Hyperinflated lungs flatten the diaphragm, weakening it
50
What does flattening of the diaphragm cause? 1) Nostril flaring, coordinated breathing, and relaxed respiratory muscle tone 2) Uncoordinated breathing and relaxed respiratory muscle tone 3) Use of accessory muscles, air hunger sensation, uncoordinated breathing
**3)** Use of accessory muscles, air hunger sensation, uncoordinated breathing because inhalation starts before exhalation is complete
51
How does decreased gas exchange surface affect acid base balance and SpO2? 1) Causes respiratory alkalosis and low SpO2 2) Causes respiratory acidosis and low SpO2 3) No changes in acid base balance but increases SpO2 4) Respiratory acidosis and high SpO2
**2)** Respiratory acidosis and low SpO2
52
What three signs characterize chronic bronchitis? 1) Increased mucus production, chronic cough, inflammation of bronchioles 2) Decreased mucus production, acute cough, inflammation of bronchioles 3) Increased mucus production, chronic cough, inflammation of alveoli
**1)** Increased mucus production, chronic cough, inflammation of bronchioles
53
What causes chronic bronchitis?
Cigarette smoke is the main cause and other inhaled irritants can cause it leading to increased proteases, elastin breakdown = air trapping and reduced gas exchanged, cilia are also impaired harming cilial removal of mucus and fluid
54
How is air trapped in chronic bronchitis?
Thick mucus and narrowed airways due to inflammation trap air
55
What causes infection risk in chronic bronchitis? 1) Increased cough resulting in the patient placing their hands near their mouth frequently 2) Air trapping reducing fresh air in the alveoli allowing bacteria to proliferate 3) Increased mucus production allowing bacteria to proliferate
3) Increased mucus production allowing bacteria to proliferate
56
Describe cor pulmonale and how it developes in COPD
It is right-sided heart failure caused by chronic bronchitis and/or emphysema. Decreased blood flow d/t air trapping and stiff alveoli walls -> increases pressure -> narrowing long blood vessels -> increased heart workload against pressure -> right heart enlarges and thickens -> right-sided HF develops with venous backup
57
What are ways to prevent COPD?
**1)** Quit smoking and vaping **2)** Avoid particulate matter (work exposure, hobby exposure, wear proper PPE)
58
What are the 3 most accurate risk factors for COPD? 1) Male, under 65 years old, history of particulate exposure 2) Female, 65 years and older, history of cigarette smoking 3) Female, 65 years and older, chronic sputum production
2) Female, 65 years and older, history of cigarette smoking - not males, 65 years and older, sputum production is not a risk factor it is a symptom
59
List some signs and symptoms of COPD:
- thin, loss of muscle mass in extremities - enlarged neck - slow moving - orthopnea (difficulty breathing while lying down) - accessory muscle use - RR 40-50 (emergency) - Sits forward in tripod position - Barrel chest (anterior and posterior chest are same size) - Delayed capillary refill - Finger clubbing - Dependent edema
60
What does an ABG look like in COPD? 1) Respiratory acidosis and metabolic acidosis 2) Respiratory alkalosis and metabolic acidosis 3) Respiratory acidosis and metabolic alkalosis 4) Respiratory alkalosis and metabolic alkalosis
**3)** Respiratory acidosis (you have poor O2 exchange and hypercapnia) and metabolic alkalosis because the body is chronically absorbing bicarbonate to compensate
61
What is the primary lab in diagnosing COPD?
ABGs
62
Which lung volume is most affected in COPD? 1) Residual volume 2) Inspiratory reserve volume 3) Expiratory reserve volume 4) Tidal volume
**1)** Residual volume b/c of air trapping, more air is left over increasing residual volume significantly
63
What is the main priority in COPD and what are three other priorities?
**1) Maintaining airway and gas exchange** **2)** Weight loss d/t dyspnea (a lot of metabolic work to breathe hard) **3)** Fatigue d/t low O2 but high demand **4)** Infection risk - pneumonia
64
How do SABA (short acting beta agonists) work? What education should you provide to the patient with COPD?
**1)** They induce bronchodilator by relaxing smooth muscle via activation of pulmonary beta-2 receptors **Education:** - Carry your inhaler at all times for life-saving moments - Know that it may cause your heart rate to go up along with systemic symptoms because it is non-specific - Take your SABA inhaler 5 minutes before other inhaled agents to improve their effects
65
Albuterol can be used for acute COPD exacerbations. What medication can also be used for COPD exacerbations? 1) Tiotropium 2) Salmeterol 3) Fluticasone 4) Ipratropium
**4)** Ipratropium - Tiotropium is the same medication class as ipratropium, cholinergic agonists, but tiotropium is a long-acting agent while ipratropium is a short-acting agent helpful for COPD exacerbations
66
How do long-acting beta agonists assist in COPD? Can they be used for acute COPD relief? What are some of these medications?
- LABAs relax bronchial smooth muscle by activating pulmonary beta-2 receptors. - No, they cannot be used for acute COPD exacerbation, they have a slow onset **Medications:** - Salmeterol, indacterol, formoterol "-erols"
67
How do cholingeric antagonists (Anticholinergics) assist in COPD? What are some education points? What are some of these medications?
- They cause bronchodilation by inhibiting PSNS allowing SNS to dominate releasing epinephrine for pulmonary beta-2 receptor activation - They prevent bronchospasm and improve gas exhcange **Education:** - If a reliever (ipratropium), carry at all times - Shake inhaler well if it is a metered dose inhaler - Increase daily fluid intake d/t mouth dryness - Report blurred vision, headache, eye pain, nasuea, tremors, dryness as they are signs of an overdose **Medications:** aclidinium, ipratropium, tiotropium, umeclindium, "-iums"
68
How do corticosteroids help in COPD? What are important education points? What are some corticosteroid medications?
- They help in COPD by disrupting inflammatory pathways reducing mucus production and relieving narrowed airways **Education:** - Use them daily even with no symptoms present because maximum effectiveness comes with 48-72 hour use - Perform good oral care because there is an increased risk of infection such as Candida - Rinse mouth after use to prevent Candida infection - It is not for symptomatic use **Medications:** fluticasone, beclomethasone, budesonide
69
How do mucolytics work in COPD? What kind of toxicity can occur? What is one medication?
- They work by thinning secretions **Education:** - Hepatotoxicity is possible **Medication:** - Acetylcystine
70
How often should patients with COPD be monitored? 1) Q4H 2) Q6H 3) Q1H 4) Q2H
**4)** Q2H
71
What are two breathing techniques to use for patients with COPD? 1) Diaphragmatic breathing and nostril flaring 2) Pursed lip breathing and tripod position 3) Pursed lip breathing and diaphragmatic breathing 4) Tripod position and high fowlers
**3)** Pursed lip breathing and diaphragmatic breathing - Tripod, high fowlers, and nostril flaring can help with oxygenation but are not breathing techniques
72
What oxygen saturation should patients with COPD be kept at? 1) 94-99% 2) 90-95% 3) 82-91% 4) 88-92%
**4)** 88-92% - Placing them on oxygen at a rate higher to bring them up can knock out their drive to breathe. Their breathing drive becomes more about SpO2 levels than SpCO2 levels because of chronically lowered O2 and chronically high CO2. Thus, when they are over oxygenated, their body believes it does not need to breathe.
73
How much fluid should a nurse encourage a patient with thick mucus secretions due to chronic bronchitis consume? 1) 2L/day 2) 3L/day 3) 4L/day 4) 1L/day
**1)** 2L/day to thin mucus
74
What are s/s of COPD exacerbation?
**1)** RR 40-50 **2)** O2 below 80-85% **3)** Cyanosis **4)** Altered mental status/confusion **5)** Accessory muscle use **6)** Wheezing/crackles
75
What are signs and symptoms of early hypoxia (select all that apply): 1) Bradypnea 2) Cyanosis 3) Tachycardia 4) Pale Skin (pallor) 5) Barrel Chest 6) Confusion/irritability/restless
**3)** Tachycardia **4)** Pale Skin **6)** Confusio/irritability/restless 1 and 2 are signs of late hypoxia and 5 is a sign of chronic hypoxia
76
Name early signs of hypoxia:
**1)** Confusion, irritability, restless **2)** Tachypnea (>20) **3)** Tachycardia **4)** Elevated BP **5)** Pale skin **6)** Intercostal retractions **7)** O2 <90%
77
Name signs of late hypoxia:
**1)** Stupor **2)** Cyanosis **3)** Bradypnea (< 12RR) **4)** Bradycardia **5)** Hypotension **6)** Cardiac dysrhythmias
78
Name signs of chronic hypoxia:
**1)** Nail clubbing **2)** Barrel chest **3)** Cyanosis **4)** Delayed capillary refill **5)** Pursed lip breathing
79
How can weight loss be prevented in COPD?
**1)** Eat high calorie, high protein meals **2)** Eat small frequent meals **3)** Non-gas producing foods **4)** Bronchodilator 30-min before eating to reduce difficulty eating
80
How would we know weight loss prevention in COPD is successful? If weight is kept within ______ % of ideal body weight: 1) 15% 2) 10% 3) 5% 4) 3%
**2)** 10% - weight should be kept within 10% of ideal body weight
81
What is a core issue in using inhaled anticholinergics (cholinergic antagonists)? 1) Dry mouth 2) Increased saliva production 3) Unproductive cough 4) Swelling of the tongue
**1)** Dry mouth - Anticholinergics are very drying = dry mouth, reduced saliva production, dry eyes, constipation
82
What should one take to help manage a COPD exacerbation? 1) Salmetrol and then fluticasone 2) Aceylcystine and then tiotropium 3) Albuterol or ipratropium and then salmeterol 4) Albuterol or ipratropium and then fluticasone
**4)** Albuterol or ipratropium and then fluticasone - Albuteral and ipratropium are both relieving inhalers and the inhaled coriticosteroid should be continued
83
True or false, you should hold your breath for 10 seconds after taking a puff of your inhaler
**True**, after inhaling slowly for 3-5 seconds, hold your breath for 10 seconds and then exhale
84
How long should you wait between doses of the same inhaler and doses of a different inhaled medication? 1) 1 minute for same inhaler and 5 minutes between different inhalers 2) 5 minutes for the same inhaler and 1 minute between different inhalers 3) 1 minute for the same inhaler and 1 minute between different inhalers 4) 2 minutes for the same inhaler and 5 minutes between different inhalers
**1)** 1 minute for same inhaler and 5 minutes between different inhalers
85
Pneumonia: What is it, what are signs and symptoms, and what are some diagnostics?
**What is it:** it is a lung infection due to bacteria, viruses, or fungi causing inflammation and fluid build up in the airways **S/S:** fever, chills, malaise, loss of appetite, myalgia, cough (productive or not), dyspnea, increased RR, labored breathing, crackles, rhonchi, low O2 saturation **Dx:** increased WBC, sputum culture, chest x-ray, blood culture, ABG
86
What is the priority in pneumonia and what are possible interventions?
**Priority:** impaired gas exhcange = improve **Interventions:** Increase HOB, early mobilization, O2 support, incentive spirometry, cough + deep breathing, bronchodilators
87
What two medications can treat pneumonia? 1) Penecillin and Ceftriaxone 2) Levofloxacin and albuterol 3) Ceftriaxone and Levofloxacin 4) Metoprolol and Diltiazem
3) Ceftriaxone and Levofloxacin are two different broad spectrum antibiotic classes that can treat bacterial pneumonia infections
88
Ceftriaxone and Levofloxacin: what class of antibiotic do they belong to, what side effects do they have, what teaching should you provide to patients
**1)** Ceftriaxone **- Class:** Cephalsoporin **- Side effects:** very safe overall, allergic reactions are main concern d/t cross-sensitivity to penicillin **- Teaching:** complete entire course **2)** Levofloxacin **- Class:** Fluroquinolone **- Side effects:** nausea, vomiting, swelling/rupture of tendon, c. diff and yeast infections **- Teaching:** take with food, avoid sun exposure, complete entire course
89
What are the goals and outcomes for O2, infection, and anxiety in pneumonia?
**1)** O2 will be maintained at 92% **2)** Free of infection with no fever and normal WBC **3)** Anxiety is at baseline
90
What are risk factors for peripheral artery disease?
**1)** Sedentary lifestyle **2)** Smoking **3)** Stress **4)** Older adult **5)** High fat diet **6)** Diabetes
91
What is intermittent claudication and what disease is it associated with?
**Intermittent claudication:** is the classic leg pain characterized by burning and cramping with movement stoppoing upon rest Associated with peripheral artery disease (PAD)
92
How can peripheral artery disease become dangerous? 1) It causes microbleeds in the vasculature of lower extremities 2) It causes extreme edema at later stages, decreasing perfusion 3) It can lead to ulcers that immediately lead to amputation 4) It can cause blockages in the lower extremities, leading to necrosis and gangrene
**4)** It can cause blockages or full occlusions decreasing blood flow which causes cell death, gangrene, and necrosis
93
What are symptoms of periperal artery disease? (select all that apply) 1) Hair loss 2) Dusky/pale/ashy skin 3) Puritis 4) Cold extremities 5) Petechiae 6) Muscle atrophy
**1)** hair loss **2)** Dusky/pale/ashy skin **4)** Cold extremities **6)** Muscle atrophy - Puritis (itching) and petechiae (or small purple bruising) are not characteristic of PAD
94
What diagnostic tests can be conducted to diagnose peripheral artery disease (PAD)? (select all that apply) 1) Magnetic Resonance Angiography 2) Echocardiogram 3) Ankle-brachial index 4) Venous duplex ultrasound
**1)** Magnetic resonance angiography helps to assess blood flow in arteries **3)** Ankle-brachial index - assesses brachial and ankle BP and divides ankle/brachial
95
What ankle-brachial index (ABI) is indicative of peripheral artery disease? 1) < .90 2) < .70 3) .90-1.0 4) < .80
**1)** <.90 - ankle BP will be lower than brachial d/t occlusion
96
What is the primary cause of peripheral artery disease?
**1)** Atherosclerosis
97
How is exercise beneficial in peripheral artery disease? 1) Decreases CO2 in circulation 2) Increases collateral circulation 3) Increases hair growth 4) Promotes venous stasis
**2)** Increase collateral circulation improving blood flow
98
True or false: Individuals with PAD should avoid wearing constrictive clothing and crossing their legs
**True:** both can reduce blood flow to the legs and feet
99
How can vasodilation be promoted in peripheral artery disease:
**1)** Keep yourself warm (warm house, wear socks, wear insulated shoes) - do not put warm items on skin d/t reduced sensation **2)** Prevent cold exposure b/c it causes vasoconstriction **3)** Complete abstinence from smoking and tabacco b/c it causes vasoconstriction **4)** Avoid caffeine d/t vasoconstriction
100
What two antiplatelet medications can be used for periperal artery disease? 1) Warfarin & Heparin 2) Lovenox & Aspirin 3) Aspirin & Clopidogrel 4) Clopidogrel & Apixaban
**3)** Aspirin and Clopidogrel can be used independently or dually for antiplatelet therapy
101
What should not be use with clopidogrel?
Grapefuit juice as it can reduce its effects
102
Which medication can help with intermittent claudication in peripheral artery disease? 1) Aspirin - Antiplatelet 2) Lisinopril - ACE inhibitor 3) Heparin - Anticoagulant 4) Cilostazol - Phosphodiesterase inhibitor
**4)** Cilostazol - Phosphodiesterase inhibitor helps with intermittent claudication, increase walking distance, and increase HDL levels
103
What is venous insufficiency?
**Prolonged venous hypertension causing stretching of the veins and damaging valves** leading to backup and stasis of blood
104
What are signs and symptoms of venous insufficiency?
**1)** Edema **2)** Stasis ulcers that are difficult to heal **3)** Stasis dermatitis **4)** Skin pigmentation changes (hyperpigmentation) **5)** Pedal pulses present **6)** ABI is normal
105
What are two ways to increase venous return to treat venous insufficiency?
**1)** Compression stockings - Teds (for beds) for bedridden patients - Jobst (medical compression = need prescription) for ambulatory patients **2)** Elevate legs above heart for >30 minutes/day 3-4x
106
What is the difference between ulcers in PAD and venous insufficiency?
**PAD Ulcers** - Usually on toes, on top of or in between or lateral malleolus (ankle) - Well-defined edges - No bleeding - Deep **Venous Ulcers:** - Usually on medial malleolus (inside ankle) - Uneven ulcer edges - Granulation tissue - Superficial - Hard to heal
107
What kind of dressings can be used to treat venous ulcers?
**1)** Hydrocolloid dressings placed with aspetic technique **2)** Gauze dressing moistened with zinc oxide (unna boot)
108
What are the thee parts to Virchow's Triad that contribute to DVT/VTE?
**1)** Reduced arterial flow/venous stasis (a-fib, immobility, venous insufficiency, prolonged sitting) **2)** Endothelial injury (smoking, trauma, hypertension, surgery) **3)** Hypercoagulability (sepsis, smoking, COVID-19)
109
What are symptoms of deep vein thrombosis (DVT/VTE)?
**1)** Calf/groin pain **2)** Sudden onset of unilateral leg swelling **3)** Induration (hardening of skin) **4)** Warmth/redness **5)** Edema
110
What is the diagnositc standard for deep vein thrombosis (DVT)?
Venous duplex ultrasonography to assess flow
111
What is the priority in DVT?
Prevent complications of DVT (embolus -> PE, or increase in size) and anticoagulation
112
What are interventions in DVT aside from anticoagulant therapy?
**1)** Gradual ambulation **2)** Bed rest and leg elevation **3)** Compression stockings **4)** warm, moist soaks
113
How long does it take before the therapeutic effect of warfarin is seen? Why is this important if transitioning from unfractionated heparin?
It takes 3-4 days before seeing therapeutic effect, thus warfarin and heparin must be used at the same time; heparin acts as a bridge for warfarin to start working
114
What is the reversal agent for unfractionated heparin? 1) Andexanet alfa 2) Vitamin K 3) Idarocizumab 4) Protamine sulfate
**4)** Protamine sulfate
115
What is the reversal agent for warfarin? 1) Protamine sulfate 2) Vitamin K 3) Andexanet alfa 4) Idarocizumab
**2)** Vitamin K
116
What is the reversal agent for dabigatran? 1) Protamine sulfate 2) Vitamin K 3) Andexanet alfa 4) Idarocizumab
**4)** Idarocizumab
117
What is the reversal agents for edoxaban, apixaban, and rivaroxaban? 1) Andexanet alfa 2) Vitamin K 3) Idarocizumab 4) Protamine sulfate
**1)** Andexanet alfa
118
Why should reversal agents for anticoagulants only be used as a last resort?
They cause an extreme risk for clotting
119
Which labs are primarily monitored in warfarin therapy? 1) aPTT and INR 2) INR and PT 3) PT and aPTT 4) Antifactor Xa and XIa
**2)** INR and PT
120
When would one consider administering protamine sulfate to reverse heparin treatment? 1) If the therapeutic range of PTT is >90 seconds 2) If the therapeutic range of aPTT is >50 seconds 3) If the therapetuic range of aPTT is >100 seconds 4) If the therapeutic range of PTT is < 175 seconds
**3)** If the therapeutic range of aPTT >100 seconds - This indicates the blood is taking too long to clot and they are at high risk of bleeding
121
Which labs are primarily monitored in heparin therapy? 1) aPTT and INR 2) INR and PT 3) PT and aPTT 4) PTT and aPTT
**4)** PTT and aPTT
122
How often should PT and INR be drawn for warfarin therapy at the start of therapy? 1) Q24H (1x/day) 2) Q6H (4x/day) 3) Q12H (2x/daily) 4) Q3H (8x/day)
**1)** Q24H (1x/day) to monitor therapeutic range
123
How often should aPTT be drawn for warfarin therapy?
6 hours after the initial dose and then after every dose given
124
What is the therapetuic range for INR for DVT treatment? 1) 3-4 2) 1.5-2 3) 2-3 4) 1-2
**3)** 2-3 for treatment of DVT - 1.5-2 is for DVT prophylaxis
125
What are two benefits of taking direct oral anticoagulants (apixaban, rivaroxaban, endoxaban) aside from their direct action of thinning the blood?
**1)** There are fewer drug interactions **2)** There is less frequent lab monitoring
126
What are the signs/symptoms of bleeding to monitor for while a patient is on anticoagulant therapy?
**1)** Sudden bleeding of the gums or nose **2)** Petechiae or ecchymosis (bruising) **3)** Hematuria (blood in the urine) **4)** Abdominal pain **5)** Altered mental status **6)** Tachycardia **7)** Hypotension **8)** Tachypnea
127
What should be taught to a patient starting on anticoagulants?
**1)** S/S of bleeding and report any bleeding **2)** Do not use a straight razor, use an electric razor **3)** Do not abruptly stop medications **4)** Take at the same time each day
128
What kinds of emboli can cause pulmonary embolsim?
**1)** Air **2)** Fat **3)** Amniotic **4)** Cancer **5)** DVT clot (most common)
129
List the four concerns in order of priority in pulmonary embolsim? - Anxiety - Hypotension - Hypoxemia - Bleeding
**1)** Hypoxemia (V/Q) mismatch **2)** Hypotension (left ventricle left with inadequate flow) **3)** Bleeding (due to anticoagulant therapy) **4)** Anxiety (related to hypoxemia and threat to life)
130
What are some signs and symptoms of impaired gas exhange during pulmonary embolism?
**1)** Sudden dyspnea **2)** Tachypnea **3)** Sharp, stabbing chest pain **4)** Feeling of impending doom **5)** Lightheaded **6)** Diaphoresis **7)** Cough **8)** Hemoptysis (bloody sputum)
131
What are some signs and symptoms of impaired perfusion during pulmonary embolism?
**1)** Tachycardia **2)** Distended neck veins **3)** Crackles in lungs d/t edema **4)** Hypoxia **5)** Cyanosis **6)** Pulmonary hypertension **7)** Systemic hypotension
132
What is the diagnostic imaging standard for pulmonary embolism?
CTPA: Computed Tomography Pulmonary Angiography
133
What labs can you examine to help determine pulmonary embolism?
**1)** D-dimer (clot breakdown) >250 ng/mL **2)** ABG (metbolic acidosis d/t lactic acid build up) **3)** Troponin (elevated) **4)** BNP (elevated)
134
What nursing interventions should be taken during pulmonary embolism to address hypoxemia?
**1)** Call rapid response team **2)** Administer supplemental O2 if below 90% **3)** Place in semi-fowler's position **4)** Obtain IV access **5)** Heparin bolus or use LMWH if HIT is a concern **6)** Alteplase if severe **7)** Assess cardiac and respiratory systems **8)** ABGs **9)** Vitals
135
When should alteplase be used during pulmonary embolism?
Only if the patient is becoming unstable such as going into shock
136
What nursing interventions should be taken during pulmonary embolism to address hypotension?
**1)** Administer IV crystalloid fluids to restore plasma volume and prevent shock **2)** Monitor urine output **3)** Monitor mucus membranes and skin turgor **4)** Monitor s/s of heart failure **5)** Vasopressors if fluids are failing
137
What nursing interventions should be taken during pulmonary embolism to address bleeding?
**1)** Have reversal agents ready (Warfarin = vitamin K, heparin = protamine sulfate) **2)** Monitor for s/s of bleeding (hypotension, increased HR, abdominal distension/pain, sudden bleeding or bruising without cause, hematura, hemoccult stool) **3)** CBC/PLT labs
138
What is a closed pnueomothorax?
When the pleural cavity has less pressure than atmospheric causing air to leak into the chest from the lungs
139
What is an open pneumothorax?
When the pleural cavity has equal pressure to atmohspheric caused by a hole in the chest wall leaving the lungs open to the outside
140
What is a tension pneumothorax and why is it life-threatening
A tension penumothorax is a type of closed pneumo when the pleural cavity pressure is greater than atmospheric. It is dangerous because air continues to build up in the chest cavity, but cannot exit because the punctured lung acts as a 1-way valve allowing air into the chest, but covers the hole during expiration so it cannot leave. The build up of air can place pressure on the heart and trachea deviating them.
141
What are causes of pneumothorax?
**1)** Medical procedures **2)** Underlying conditions like COPD **3)** Chest trauma
142
What are signs and symptoms of pneumothorax?
**1)** Respiratory discomfort **2)** Chest pain **3)** Shortness of breath **4)** Tachypnea **5)** Assymetric lung expansion **6)** Decreased or absent lung sounds on affected side **7)** Tachycardia **8)** Hypotension **9)** Tracheal deviation **10)** Jugular vein distension **11)** Cyanosis
143
What is the main diagnostic imaging for pneumothorax?
Chest x-ray
144
Where is the air drain and fluid drain placed in patients with a chest tube?
Air drain is placed high on the lung apex Fluid drain is placed low near the lung base
145
Why is it important that fluid be drained from the drainage system or that a new system be connected if one is filled during chest tube drainage?
Because if fluid backs up from the system into the tube drainage can stop and cause another penumothorax or effusion
146
How often should the nurse monitor the drainage system after chest tube placement within the first 24 hours? 1) Q1H 2) Q2H 3) Q4H 4) Q6H
**1)** Q1H
147
How many centimeters (cm) of water should be placed in the water seal chamber of the chest tube drainage system? 1) 4cm 2) 1cm 3) 2cm 4) no water is needed
**3)** 2cm so air does not go back into the patient
148
What might a mild/moderate amount or excessive amount of bubbling in the water seal chamber indicate?
Mild-moderate bubbling indicates that air is passing through the chamber which is normal Excessive bubbling indicates a leak is present
149
What is tidaling in relation to the chest tube system? What might an absence of tidaling indicate?
**Tidaling:** the normal rise of water-seal chamber liquid by 2-4cm during inhalation and fall during exhalation **Absence of tidaling** can indicate that the lung is healed or there is an obstruction in the tube
150
What should be kept next to the bedside of a chest tube system?
**1)** Padded clamps **2)** Sterile gauze
151
What is sinus tachycardia?
SA node discharge rate of >100 BPM
152
What are possible causes of sinus tachycardia?
**1)** Fever/infection **2)** Pain **3)** Anxiety/Fear **4)** Caffeine **5)** Hypovolemia
153
What are some signs and symptoms of sinus tachycardia?
**1)** Palpitations **2)** Chest pain **3)** Dizziness **4)** SoB
154
How is perfusion affected with prolonged sinus tachycardia?
Prolonged tachycardia decreases coronary perfusion time, decreases diastolic filling, and reduced coronary perfusion pressure = low O2 ouput with high O2 demand
155
How do you treat sinus tachycardia?
**1)** Treat underlying cause **2)** Treat/mitigate fall risk
156
What is sinus bradycardia?
SA node discharges at **< 60BPM**
157
What are causes of sinus bradycardia?
**1)** Vomiting **2)** Suctioning **3)** Valsava maneuvers (bearing down, gagging)
158
What are signs/symptoms of sinus bradycardia?
**1)** Diaphoresis **2)** Chest pain **3)** SoB **4)** Syncope **5)** Dizziness/confusion **6)** Hypotension
159
True or false: An individual who is stable with sinus bradycardia should receive IV atropine
**False**, individuals who are stable with sinus bradycardia should not receive treatment, only patients who are symptomatic
160
What steps do you take for symptomatic sinus bradycardia?
**1)** Administer IV atropine **2)** Administer IV fluids **3)** Administer supplemental oxygen to bring above 90%
161
What surgical intervention is needed in sinus bradycardia that is not responsive to medications?
A pacemaker is needed in refractory bradycardia
162
How does atropine function to improve bradycardia? What should you monitor after administering atropine?
It is an anticholingeric medication that blocks muscarinic receptors on the heart. Therefore, it inhibits the PSNS allowing the SNS to dominate **increasing HR** **Monitor:** HR, s/s such as blurred vision, dizziness, headache, urin retention, constipation (it's very drying)
163
What is atrial fibrilation?
Atria quiver while ventricles beat at a rapid rate in response to the impulses of the atria causing a decrease in cardiac output because of poor blood filling
164
What are the signs and symptoms of atrial fibrilation?
**1)** Irregular apical pulse **2)** fatigue **3)** weakness **4)** SOB **5)** Palpitations **6)** Chest pain **7)** Anxiety
165
What tool is used to diagnose A-fib and what would you see?
12-lead ECG diagnosis **1)** No clear p-wave **2)** Irregular R-R rhythm, wont be evenly spaced **3)** Varying HR
166
What are the 4 primary risk factors for a-fib?
**1)** Hypertension **2)** CAD **3)** HF **4)** ACS
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What is the number one priority for a-fib?
Preventing embolus formation
168
What drugs are used to treat A-fib?
**1)** Diltiazem (calcium channel blocker) **2)** Metoprolol (beta-blockers) **3)** Digoxin (cardiac glycoside **4)** Warfarin **5)** Apixaban/rivaroxaban (direct oral anticoagulants)
169
What do diltiazem, metoprolol, digoxin, and amiodarone control in A-fib? 1) Rhythm control 2) Rate Control 3) Contractility control
**2)** Rate control
170
Diltiazem: what class is it, what does it do to the heart, what should you monitor and educate on?
**What is it:** calcium channel blocker **Heart effect:** slows SA and AV conduction slowing heart rate **Monitor:** Hypotension, heart rate, s/s of HF **Educate:** Slow position changes d/t orthostatic hypotension
171
Metoprolol: what class is it, what does it do to the heart, what should you monitor and educate on?
**What is it:** beta blocker **Heart effect:** slows ventricular response by decreasing catecholamines that stimulate beta receptors **Monitor:** heart rate and blood pressure, may cause bronchospasm **Educate:** Slow position changes d/t orthostatic hypotension
172
Digoxin: what class is it, what does it do to the heart, what should you monitor?
**What is it:** cardiac glycoside **Heart effect:** Increases heart **contractility,** slows AV conduction, decrease SNS activity, slows heart rate, **beneficial for HF with A. fib** **Monitor:** Assess apical pulse for 1 minute before giving, digoxin toxicity, potassium levels becuase it can cause hyperkalemia **Educate:** s/s of digoxin toxicity (fatigue, anorexia, blurred vision, mental status change)
173
What 2 events cause digoxin toxicity?
**1)** Hypokalemia (this triggers toxicity and taking digoxin can also cause hyperkalemia as a separate issue) **2)** High digoxin doses
174
Warfarin: what class is it, what does it do to the heart, what should you monitor, patient education?
**What is it:** anticoagulant via vitamin K-depend clotting factor inhibition **Heart effect:** Thins blood to prevent clotting in the heart **Monitor:** INR, s/s of bleeding **Educate:** Avoid ginseng, ginger, ginko, and garlic which can interfere with medication, avoid or stay consistent with vitamin K, s/s of bleeding
175
Apixaban, Rivaroxaban, Endoxaban: what class is it, what does it do to the heart, what should you monitor?
**What is it:** Direct Oral Anticoagulants **Heart effect:** Thins blood to prevents clots in the heart **Monitor + Educate:** s/s of bleeding
176
What 2 contributions do Warfarin and Direct Oral Anticoagulants have in A-fib?
**1)** Stroke, PE, DVT prevention **2)** Help to convert a-fib back to sinus rhythm
177
What heart rate must you hold diltiazem, metoprolol, and digoxin?
Hold if **below 60 HR** and contact provider
178
What are the signs and symptoms of atrial fibrillation? (Select all that apply) 1) Irregular Pulse 2) Fatigue 3) Shortness of Breath 4) Bounding Pulse 5) Palpitations 6) Hypotension 7) Headache
**1)** Irregular Pulse **2)** Fatigue **3)** Shortness of Breath **5)** Palpitations **6)** Hypotension
179
What are the important priorities in treating patients with atrial fibrillation? (Select all that apply) 1) Fall prevention 2) Pain management 3) Preventing emboli formation 4) Nutritional screening 5) Antiarrhythmic medications to prevent heart failure
**3)** Preventing emboli formation **5)** Antiarrhythmic medications to prevent heart failure
180
When educating a patient who was recently prescribed warfarin, what dietary considerations would you instruct them to implement? 1) Add foods like garlic and ginger to food to improve micronutrient intake to improve INR 2) Maintain a consistent vitamin K intake or avoid vitamin K foods 3) Increase calcium intake through supplementation and dairy products 4) Take vitamin B12 supplements to improve absorption of warfarin
**2)** Maintain a consistent vitamin K intake or avoid vitamin K foods
181
You are caring for a 68 year old male after a fall. He has a history of atrial fibrillation and is prescribed warfarin. Head CT revealed a subdural hemorrhage. What order would you anticipate receiving from the physician? 1) Administer vitamin K and prothrombin complex concentrate 2) Administer TXA 3) Administer TPA 4) Administer 1 unit of PRBCs and 1 unit of platelets
**1)** Administer vitamin K and prothrombin complex concentrate - Both help reverse the effects of Warfarin. While TXA can help prevent excessive bleeding, it does not target warfarin's action specifically
182
What is v-tach and how many BPM?
**V-tach:** repeitive firing of the ventricles d/t irritable ventricular foci with **3 or more consecutive premature ventricular contractions** **BPM:** 140-180
183
What ECG findings indicate V-tach?
**1)** Wide QRS **2)** R-R interval is regular **3)** No visible p-waves **4)** Rapid BPM 140-180
184
What are risk factors for V-Tach?
**1)** Illicit drug use like cocaine and inhalants **2)** Ischemic heart disease **3)** Hyper/hypokalemia **4)** HF **5)** Alcohol use
185
What are signs and symptoms of V-Tach?
**1)** Dizziness **2)** Angina **3)** SOB **4)** Palpitations
186
What 3 steps do you take in V-tach with a pulse?
**1)** Call for help **2)** Attach ECG pads for 12 lead **3)** Give amiodarone (150mg) and help with cardioversion
187
What steps do you take in pulseless V-tac?
**1)** Call 911/call for help/Rapid response **2)** Get defebrilator or delegate someone to get it **3)** Start CPR and continue it even while defibrilator is being set up
188
What is ventricualr fibrilation (V. fib)?
- It is when there are many irritable foci firing totaly disorganized - No ventricular contraction - **The ventricles quiver consuming a large amount of oxygen**
189
Why is V. fib life-threatening and how fast is it fatal?
- There is no cardiac output, no pulse, no perfusion anywhere - It is rapdily fatal in 3-5 minutes
190
What are some causes of V. fib?
**1)** Acute MI **2)** HF **3)** Acidosis **4)** hyper/hypokalemia **5)** hypomagnesemia
191
What are signs/symptoms of V. fib?
**1)** Pulseless **2)** Apneic **3)** Unresponsive **4)** Pupils dilated and fixed
192
What steps should you take during V. fib?
**1)** Call code/call 911 **2)** Start CPR **3)** Continue CPR and defibrilate as soon as possible
193
What should you look for on an ECG to indicate V. fib?
- No recognizable deflection - No discernable pattern, chaos
194
What is ventricular asystole?
Absence of any ventricular rhythm; no electrical impulses anywhere, no perfusion
195
What can cause ventricular asystole?
**1)** Severe hyperkalemia **2)** Acidosis **3)** MI **4)** HF
196
What should you do for a patient in ventricular asystole?
**1)** Call 911/call code **2)** Start CPR
197
What rhythms can you shock (defibrilate)? (Select all that apply) **1)** Asystole **2)** Atrial fibrilation **3)** Pulseless Ventricular Tachycardia **4)** Ventricular Tachycardia with a pulse **5)** Ventricular fibrilation **6)** Sinus tachycardia
**3)** Pulseless Ventricular Tachycardia **5)** Ventricular fibrilation
198
At what depth should you perform compressions?
2-2.4 inches
199
How often do you give breaths during CPR when an advanced airway is in place?
Every 6-8 seconds
200
What is the ratio for compression to breaths in CPR? What is the rate for compressions and breaths per minute?
- 30 compression : 2 breaths - 100-120 compressions/minutes and 10-12 breaths/minute
201
What does acute coronary syndrome encompass? (select all that apply) 1) Unstable angina 2) STEMI 3) Stable angina 4) NSTEMI 5) Ischemia
**1)** Unstable angina **2)** STEMI **4)** NSTEMI
202
What characterizes stable angina?
**1)** Familiar pattern **2)** Occurs with exertion **3)** Relieved at rest **4)** < 15 minutes **5)** Relieved by nitroglycerin
203
What characterizes unstable angina?
**1)** Pain intensity increases **2)** Attacks vary **3)** Occurs without exertion **4)** Is **not** relieved by rest **5)** >15 minutes **6)** Poorly relieved by nitroglycerin **7)** **may have ST changes** **8)** **NO** troponin changes
204
What are the signs and symptoms of a heart attack/MI?
**1)** Chest pressure **2)** Discomfort **3)** SoB **4)** Nausea **5)** Pain/pressure/discomfort lasts longer than 30 minutes **6)** Pain relieved only by opioids **7)** Pain raidiates to jaw, arm, or back **8)** Occurs **w/o cause often in the morning**
205
What signs and symptoms of a heart attack/MI are more commonly seen in biologically female individuals?
**1)** SoB **2)** Pain between shoulder blades **3)** Fatigue **4)** Indigestion
206
STEMI: what ECG changes are seen, cause, treatment
**ECG:** ST elevation in 2 contiguous leads **Cause:** rupture of atheroslcerotic plaque leading to an emboli that **occludes 100%** of the coronary vessel **Tx:** percutaenous coronary intervention (PCI) - angioplasty w/ or w/o stent or fibrinolytic therapy if no PCI is available
207
NSTEMI: what ECG changes are seen, cause, treatment
**ECG:** ST depression and T wave inversion **Cause:** vasospasm, dissection, or narrowing/partial occlusion of the vessel by thrombus or atheroclserosis **Tx:** Administer 325mg of aspirin, administer clopidogrel if needed, administer beta blocker 1-2 hours after MI, ACE/ARB 24 hours after, statin for abnormal lipids
208
What is the "door-to-balloon time" in the treatment of a STEMI using percutaenous intervention? 1) < 30 minutes 2) < 60 minutes 3) < 90 minutes 4) < 20 minutes
**3)** < 90 minutes - STEMIs can be rapidly fatal if the vessel if left occluded and must be treated within 90 minutes of arrival at the hospital
209
A patient presents to the emergency department with symptoms of a myocardial infarction. As the nurse, should you: 1) Continue taking a detailed history to obtain what occurred before they came in? 2) Administer alteplase to break up the embolus occluding the artery? 3) Delay taking a detailed history and assess the patients symptoms with yes or no questions? 4) Call a rapid and start CPR to restore coronary perfusion?
**3)** Delay taking the history and assess the patients symptoms with yes or no questions - You should stop taking a detailed history and do a brief assessment using yes or no questions. The other options are not correct in the current scenario, you should assess your patient first
210
A patient comes into the ED with a STEMI. There is no catheterization lab available at your hospital to perform a percutaneous coronary intervention. What is the alternative treatment and how soon should it be done? 1) Administer Tranexamic acid (TXA), within 30 minutes 2) Administer tissue plasminogen activator (TPA), within 30 minutes 3) Administer unfractionated heparin, within 90 minutes 4) Administer aspirin, within 30 minutes
**2)** Administer tissue plasminogen activator (TPA) also known as Alteplase within 30 minutes of a STEMI with no PCI available
211
In what time frame should you obtain a 12-lead ECG after someone presents with chest pain? 1) < 10 minutes 2) < 30 minutes 3) < 5 minutes 4) < 90 minutes
**1)** < 10 minutes
212
After a myocardial infarction, which medication should you avoid and which is appropriate to take for pain management? 1) avoid Tylenol, take NSAIDs 2) avoid aspirin, take NSAIDs 3) avoid NSAIDs, take Tylenol 4) Avoid NSAIDs, take aspirin
**3)** Avoid NSAIDs, take tylenol - NSAIDs can contribute to bleeding so it is best to use Tylenol for pain management following an MI
213
Which two labs indicate a myocardial infarction is likely? (select all that apply) 1) Troponin 2) INR 3) Creatinine kinase 4) Increased Ca2+
**1)** Troponin **3)** Creatinine kinase
214
Nitroglycerin: what does it do, how many times can you give it, when should you hold it, contraindications
**What does it do:** it dilates the blood vessels allowing for blood to move past an occlusion during an MI or partial occlusion to relieve pain and restore flow **How many times can you give:** a total of 3 times 5 minutes between each dose HOLD IF SYSTOLIC BP IS **< 100 mmHG** **Contraindications:** low BP, taking any erectile dysfunction medications such as **sildenafil or any other "-afils"**
215
How long is nitroglycerin good for after opening? 1) 1 year 2) 30 days 3) 1-3 months 4) 3-5 months
**4)** 3-5 months
216
How should a patient know that oral nitroglycerin is fresh and works?
If it burns when placed under the tongue
217
How should nitroglycerin be stored?
In an airtight container that blocks out sunlight
218
When should a patient outside of a hospital setting call 911 when using nitroglycerin?
They should call 911 after taking 1 pill with no chest pain relief within 5 minutes
219
When should morphine be used during myocardial infarction? What should you monitor after administering?
**Use:** used during MI if pain is not relieved by nitroglycerin **Monitor:** BP, RR (can cause respiratory depression), HR, and vomiting
220
Why is pain management important during acute coronary syndrome?
Managing pain reduces metabolic activity reducing oxygen demand
221
When should oxygen be administered during angina/myocardial infaction?
If the patient is hypoxemia below 90% to bring their SpO2 up
222
What position should an individual be placed in during a myocardial infarction? 1) Tripod 2) High fowler's 3) Semi-fowler's 4) Supine
**3)** Semi-fowlers - this helps with oxygenation and prevents too little blood from reaching the brain as in tripod or high fowler's - supine does not provide comfort and oxygen support
223
A patient asks a nurse when they can resume having sex after their heart attack. The nurse should inform them that they can resume sexual activity once they can: 1) Walk 2 blocks without any symptoms 2) Run 2 miles without any symptoms 3) Climb 2 flights of stairs without any symptoms 4) Engage in any vigorous activity for 2 minutes without any symptoms
**3)** Climb 2 flights of stairs without symptoms
224
A post-MI patient is being discharged. A nurse is educating them on exercise and walking therapy. The nurse should tell the patient to stop walking when what occurs?
**1)** If they experience dyspnea **2)** If they begin to have angina **3)** Their target HR is exceeded, often 20BPM more than goal HR
225
What is anemia and why is it a problem?
**What:** It is an abnormally low amount of RBCs, Hgb concentration, or hematocrit **Problem:** diminishes O2 carrying capacity to tissue and organs
226
What is the most common type of anemia? 1) Blood loss anemia 2) Iron-deficiency anemia 3) Hemolytic anemia 4) Pernicious anemia
**2)** Iron-deficiency anemia
227
What are signs and symptoms of anemia?
**1)** Fatigue **2)** Pallor **3)** Cold, cold sensitivity **4)** Extertional dyspnea **5)** Somnolence (sleepy/tired) **6)** Numbness/tingling **7)** Headache **8)** Smooth, bright red tongue (pernicious anemia)
228
What vitamin can help absorb iron? 1) Vitamin C 2) Vitamin A 3) Vitamin D 4) Vitamin B12
**1)** Vitamin C
229
230
What is the normal blood pressure range?
**Systolic:** < 120 mmHG AND **Diastolic:** < 80 mmHg
231
What blood pressure range is the beginning of hypertension?
**Systolic:** 130-139 mmHG OR **Diastolic:** 80-89 mmHG
232
What are possible causes of primary hypertension?
**1)** Physical inactivity **2)** Smoking **3)** Obesity **4)** Family history of hypertension **5)** 60 years or older **6)** Stress
233
What complications can hypertension lead to?
**1)** Stroke **2)** MI **3)** PVD **4)** CKD
234
What are possible causes of seondary hypertension?
**1)** CKD (cause and complication) **2)** Pregnancy **3)** Oral contraceptives **4)** Cushing's
235
What are signs and symptoms of hypertension?
**1)** Blood pressure of >130 mmHg systolic or >80 mmHg **2)** Headaches **3)** Dizziness **4)** Flushing **5)** Often asymptomatic - "silent killer"
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How is orthostatic hypotension defined?
Loss of 20 mmHg systolic or 10 mmHg within three minutes after moving from a lying/sitting position to standing
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How much should sodium be limited to per day in hypertension? 1) 2-3g 2) < 2g 3) < 1.5g 4) < 2.5g
**3)** < 1.5g of sodium per day
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What are lifestyle modifications that individuals with hypertension should be encouraged to make? (Select all that apply) 1) Reduce or stop smoking 2) Increase the amount of protein they receive from deli meat and canned foods 3) Abstain or decrease alcohol consumption 4) Increase physical activity 5) Engage in intermittent fasting 6) Modify their diet to a plan like the DASH diet 7) Increase their stress levels through vigorous exercise 8) Lose weight
**1)** Reduce or stop smoking **3)** Abstain or decrease alcohol consumption **4)** Increase physical activity **6)** Modify their diet to a plan like the DASH diet **8)** Lose weight - They should also reduce their caloric intake, and increase their calcium, potassium, fiber, and low-fat intake
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What is the best way to improve medication adherence in hypertension? 1) Make treatment occur 1x/day 2) Provide positive reinforcement for taking medication like coupons 3) Set up a pill box for all of their medications throughout the day 4) Educate them on the side effects they may experience while taking their medication
**1)** Make treatment occur 1x/day - It's best to make treatment 1x/day and if possible, only one type of medication to reduce the time spent thinking about their medication and negative side effects
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What is the preferred class of pharmacological treatment in hypertension and which drug from that class is preferred? 1) Angiotensin Receptor Blockers (ARBs), Losartan 2) Angiotensin Converting Enzyme Inhibitor (ACEIs), Lisinopril 3) Diuretics, Hydrochlorothiazide 4) Calcium Channel Blocker, Diltiazem
**3)** Diuretics, Hydrochlorothiazide - Diuretics are the drug class of choice becuase they can quickly remove excess fluid and sodium reduce blood pressure - Hydrochlorothiazide is preferred over loop or potassium sparing becuase it is low cost, highly effective in uncomplicated hypertension, reduce calcium excretion reducing kidney stone risk, and is self-limiting thus in older adults reducing the risk of over diuresis
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What blood pressure constitutes a hypertensive crisis?
Greater than >180 mmHg systolic AND/OR >120 mmHg diastolic - This constitutes a medical emergency
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What are the signs and symptoms of a hypertensive crisis aside from blood pressure? | Think of preeclampsia/eclampsia
**1)** Severe headache **2)** Blurred vision **3)** Dizzy **4)** Nose bleeding **5)** Uremia **6)** Anxiety
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What 3 steps should you take when someone is in a hypertensive crisis?
**1)** Place in semi-fowlers **2)** Administer O2 if they are becoming hypoxic to keep it above 90% **3)** Call rapid response/911
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Hydrochlorothiaizde: what is it, when is it used, monitoring, and education
**What is it:** a thiazide dieuretic that removes water, sodium, and potassium from the body **Used:** #1 treatment for hypertension, and can be used in heartfailure during fluid volume overload, but loop diuretics are preferentially used **Monitoring:** - S/S hypokalemia (weakness, decreased reflexes, irregular pulse) - S/S dehydration - Glucose levels - Renal function (BUN and Creatinine) - Tinnitus (and other hearing problems but less common in thiazides than in loops) - Uric acid retention - may be harmful for those with gout **Education:** - Eat foods high in potassium - Rise slowly d/t orthostatic hypotension - Take in the morning to avoid nocturia - May affect blood glucose control - May cause decreased libido in males - Report tinnitus, changes in pulse, and any weakness
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What are possible causes of heart failure?
**1)** MI **2)** Hypertension **3)** CAD **4)** Valvular disease/dysfunction
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What is systolic heart failure with reduced ejection fraction (HFrEF)?
When the heart cannot contract forcefully enough during systole to eject enough blood out, often leads to fluid back up into the atria and pulmonary system **Ejection fraction: < 40%**
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What is diastolic heart failure with reduced ejection fraction (HFpEF)?
When the ventricle cannot adequately relax during diastole preventing adquate blood filling for cardiac output. Ventricles become less compliant over time becuase you need more pressure to move the same amount of volume Ejection fraction is preserved becuase while you have less filling, you still push out an adequate amount keeping the proportion similar. **EJ: < 40%**
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What are signs and symptoms of left heart failure?
**1)** Poor activity tolerance = dyspnea and fatigue **2)** Daytime oliguria and nighttime nocturia **3)** Angina **4)** Confusion, dizziness **5)** Restless **6)** Pallor/ashen skin **7)** Tachycardia **8)** Weak pulses **9)** Cool extremities **10)** Pulmonary congestion/edema **11)** Orthopnea - will sleep upright and/or with a lot of pillows
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What are signs/syptoms of pulmonary congestion/edema?
**1)** Frothy, pink-tinged sputum **2)** Tachypnea **3)** Hacking cough **4)** Crackles near the base of the lungs **5)** Restless **6)** Pulmonary hypertension **7)** Systemic hypotension **8)** Oliguria
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What three steps should be taken for someone experiencing pulmonary edema?
**1)** Place in high Fowler's position (if not hypotensive) **2)** Provide O2 to keep at 90% SpO2 **3)** Administer IV push furosemide over 1-2 minutes to treat edema and to avoid ototoxicity - Can also use nitroglycerin to reduce preload and afterload lessening fluid build up
251
What are signs and symptoms of right-sided heart failure?
**1)** Peripheral edema **2)** Ascietes **3)** Enlarged liver and spleen **4)** Neck vein distension **5)** Swollen hands/fingers **6)** Polyuria at night as fluid is mobilized **7)** Clothing and accessory do not fit well **8)** Weight gain (10-15 lbs) **9)** Anorexia **10)** Nausea
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Why is edema a poor indicator of heart failure? What is a better measure and what should you educate the patient on when they do this?
Edema is a poor measure because it take a lot of fluid retention before edema becomes apparent in heart failure **Weight** is a better measure. **Education:** - Take your weight daily - Take your weight at the same time each day - Take your weight, preferrably in the morning before you've eaten anything - Take your weight wearing the same clothing each time
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How much weight gain per day and week might indicate heart failure?
2-3kg in one day 5-6kg in one week
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What labs are elevated in heart failure? (Select all that apply) 1) BNP 2) Troponin 3) Creatinine 4) BUN 5) Hematocrit 6) GFR
**1)** BNP **2)** Troponin **3)** Creatinine **4)** BUN - Hematocrit is not elevated, it is often lowered to do fluid dilution - GFR is typically lowered which is why we see high creatinine and BUN d/t poor kidney filtration
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What is the diagnostic standard for heart failure? 1) Venous duplex ultrasonography 2) CTPA 3) Magnetic Resonance Angiography 4) Echocardiogram
**4)** **Echocardiogram**, can see valvular changes, pericardial effusion, chamber enlargement, vetricular hypertrophy, and most importantly, **ejection fraction**
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What is the drug class of choice for patients with heart failure and no fluid volume overload? What about for patients with fluid volume overload?
DoC w/ no fluid volume overload are Angiotensin Converting Enzyme Inhibitors -> **ACEIs** DoC for HF with fluid volume overload are **diuretics, mainly loop such as furosemide**
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If ACE inhibitors do not work for a patient, what might be a second appropriate medication? 1) Lisinopril 2) Losartan 3) Hydrochlorothiazide 4) Digoxin
**2)** Losartan, we would want to switch to an ARB if ACEIs do not work for the patient
258
ACE inhibitors are very helpful drugs for patients with heart failure; however, they can cause a very annoying side effect that may prompt patients to switch to an ARB instead. What is the side effect? 1) Puritis 2) Rhinitis 3) Dry mouth 4) Cough
**4)** Cough, is a side effect of ACEIs and patients should be switched to an ARB instead
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ACEIs/ARBs: what do they do, medications, monitoring, patient education
**What do they do:** both suppress the RAAS which helps vasodilate vessels and increase sodium and water excretion decreasing afterload and improving stroke volume **Medications:** - ACEIs = -"april" -> lisinopril, clanapril, captopril - ARBs = "-artan" -> losartan, valsartan **Monitoring:** - Hold if patients PB < 100 mmHg systolic - S/S of hyperkalemia - Angioedema - If BP drops below 90 mmHg systolic elevate legs **Education:** - Rise slowly d/t orthostatic hypotension - Decrease potassium rich foods in your diet
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Beta-blockers: what do they do, medications, monitoring, patient education
**What do they do:** They block beta receptors on the heart reducing catecholamine (Epi, Nor epi, dopamine) stimulation thereby reducing heart rate and blood pressure. **Medications:** "-olol" -> atenolol, metoprolol **Monitoring:** - Heart rate, do not give if below 60 BPM - Blood pressure, do not give if below 100 mmHg systolic **Education:** - Rise slowly d/t orthostatic hypotension - May cause fatigue, weakness, depression, or sexual dysfunction - **Do not stop abruptly** - can cause severe rebound tachycardia - May mask hypoglycemic symptoms
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How much should sodium be limited to in heart failure?
2g/day
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How much fluid should individuals be restricted to with heart failure?
2L/day
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What medications should be avoided in heart failure? 1) Acetaminophen 2) Spironolactone 3) Ibuprofen 4) Digoxin
**3)** Ibuprofen, it is a NSAID and they should be avoided as they can cause sodium and fluid retention
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What is glaucoma?
**Increased intraocular pressure** that compresses the nerves, vessels, and photoreceptors in the eye causing a loss of vision at the **periphery toward the center**
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What is more dangerous open-angle glacuoma or angle-closure glaucoma?
**Angle-closure glaucoma** as it causes complete and sudden vision loss d/t an obstruction of aqueous humor flow - **it is a medical emergency**
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What are signs and symptoms of glacuoma?
**1)** blurry vision **2)** halos around lights **3)** loss of peripheral vision **4)** poor dark vision **5)** anxiety and fear
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How is glaucoma diagnosed?
Through routine eye exams using tonometry to detect high pressure in the eye > 32 mmHg
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When using eye drops, the nurse should educate patients to perform punctal occlusion, which is where you: 1) Close and squeeze your eyes hard to prevent the eye drops from leaking out 2) Place the eye drop right in the corner of the eye at the puncta or tear duct to allow drops to enter the eye 3) Place the knuckle or tip of your funger at the puncta to prevent eye drops from entering the tear duct
**3)** Place the knuckle or tip of your funger at the puncta to prevent eye drops from entering the tear duct - Punctal occlusion should be done to prevent eye drops from entering systemic circulation
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What should the nurse educate patients about when they are using eye drops for the first time?
**1)** Wash your hands before instilling eye drops **2)** Do not touch the dropper to the eye surface **3)** Wait 5-10 minutes betwen drops to prevent dilution **4)** Hold pressure on the tear duct by performing punctal occlusion **5)** Use your eye drops at the sime time each day **6)** Your eyes may become blurry, sting, or burn temporarily after eye drops
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What is the goal of prostalgandins, nitrix oxides, rho kinase inhibitors, cholinergic, and mitotic agents in glaucoma?
They help drain fluid from the eye
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What is the goal of alpha agonists, beta-blockers, and carbonic anhydrase
They reduce the amount of aqueous humor in the eye
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What is the overall goal of glacoma medications?
To lower the pressure in the eyes
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What are ways to care for hospitalized individuals with vision loss?
**1)** Knock to announce yourself when entering the patient's area **2)** Orient the patient to their room/environment **3)** Provide clock face times for food locations on their plate **4)** Do not move items or rearrange without their permission **5)** Talk in a normal voice **6)** Offer your arm when walking
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What is sensorineural hearing loss, causes, and signs/symptoms?
**Sensorineural:** permanent hearing loss d/t damage to the cochlear hairs or auditory nerve **Causes:** prolonged exposure to loud noises (plane engines, lawn mowers, loud music), loop diuretics, other medications **S/S:** tinnitus, difficulty following conversations, hard to hear in loud environments
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What is conductive hearing loss, causes, and signs/symptoms?
**Conductive:** temporary hearing loss d/t external ear conditions **Causes:** cerumen build up, infection, object obstructin canal **S/S:** obstruction, speaking softly, hearing better in one ear than the other
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What should nurse education be about for hearing loss and prevention?
**1)** Wear hearing protection **2)** Receive annual hearing screens **3)** No q-tips **4)** Do not place anything bigger than your pinky into the ear **5)** Do not candle or engage in candling **6)** Take care of your hearing aid
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What are two safey considerations for those with hearing loss?
**1)** Fall risk d/t dizziness, unsteady, and fatigue **2)** Home safety - visual indicators for alarms, phones, and doorbells
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How can you improve communication for those with hearing loss?
**1)** Ensure their hearing aids are in **2)** Make sure amplifier is working **3)** Use white boards **4)** Remove loud noises **5)** Face them so that they can lip read **6)** Speak in a low octave voice **7)** Teach back education **8)** Talk to them in a well-lit room
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What are a couple of hearing aid tips?
**1)** Clean only the mold (nothing electronic) with mild soap and water **2)** Place the hearing aid in the lowest setting
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What is obstructive sleep apnea?
It is brief periods of **apnea lasting longer than 10 seconds** while asleep d/t the relaxation of neck muscles, soft palate, and tongue obstructing the airway while asleep causing intermittent hypoxia + impaired ventilation
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What are some complications of obstructive sleep apnea?
**1)** Hypertension **2)** Cardiovascular diseases **3)** Stroke **4)** Insulin resistance **5)** Dementia
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What are signs and symptoms of obstructive sleep apnea?
**1)** Fatigue **2)** Daytime sleepiness **3)** Headaches **4)** Waking up gasping **5)** Irritabiltiy **6)** Memory loss **7)** Overweight (cause + symptom) **8)** Snoring
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Is obstructive sleep apnea more common in men or women and in what age group?
More common in men Higher in those 60+ y/o
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What is the main priority in obstructive sleep apnea? What are three ways that this can be done?
Improving gas exchange **1)** Changing sleeping positions **2)** Losing weight **3)** Continuous Positive Airway Pressure (CPAP)
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What does a CPAP machine do?
CPAP provide continuous positive airway pressure, which means it continuous maintains a set pressure during inhalation and exhalation to keep the airway patent. Make sure to the mask has a good fit.
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A nurse is caring for several clients with fractures. Which client would the nurse identify as being at the highest risk for developing deep vein thrombosis (DVT)? 1) An 18-year-old male athlete with a fractured clavicle 2) A 74-year-old male who smokes and has a fractured femur 3) A 36-year-old female with type 2 diabetes and fractured ribs 4) A 55-year-old female prescribed ibuprofen for osteoarthritis
**2)** A 74-year-old male who smokes and has a fractured femur
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A client diagnosed with a large pulmonary embolism is started on oxygen but oxygen saturation has not significantly improved. What response by the nurse demonstrates an understanding of gas exchange and oxygenation in this situation? 1) “Breathing so rapidly interferes with oxygenation.” 2) “Maybe the client has respiratory distress syndrome.” 3) “The client needs immediate intubation and mechanical ventilation.” 4) The blood clot interferes with perfusion in the lungs.”
**4)** The blood clot interferes with perfusion in the lungs.”
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While assessing a client who is 12 hours postoperative after a thoracotomy for lung cancer, a nurse notices that the chest tube is dislodged. Which action by the nurse is the priority? 1) Assess for drainage from the site 2) Cover the insertion site with sterile gauze 3) Contact the primary health care provider. 4) Reinsert the tube using sterile technique.
**2)** Cover the insertion site with sterile gauze
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The nurse is caring for a client with peripheral arterial disease (PAD). Which symptom will the nurse anticipate? 1) Reproducible leg pain with exercise 2) Unilateral swelling of affected leg 3) Decreased pain when legs are elevated 4) Pulse oximetry reading of 90%
**1)** Reproducible leg pain with exercise
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A nurse is assessing a patient’s perfusion status. Which of the following findings is the best indicator of adequate tissue perfusion? 1) Blood pressure of 130/80 mmHg 2) Warm skin with brisk capillary refill 3) Urine output of 20 mL/hour 4) Heart rate of 110 beats per minute
**2)** Warm skin with brisk capillary refill
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Which features will the nurse expect to be present in a client who has long-term chronic obstructive pulmonary disease? (Select all that apply.) 1) Poor gas exchange from decreased alveolar surface area 2) Increased anteroposterior chest diameter from air-trapping 3) Arterial blood gas value with increased PaO2 level 4) Hypercapnia from retained PaCO2 5) Respiratory acidosis with a low pH
1) Poor gas exchange from decreased alveolar surface area 2) Increased anteroposterior chest diameter from air-trapping 4) Hypercapnia from retained PaCO2 5) Respiratory acidosis with a low pH
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A nurse is caring for a client who has chronic obstructive pulmonary disease (COPD). The client tells the nurse, "I can feel the congestion in my lungs, and I certainly cough a lot, but I can't seem to bring anything up." Which of the following actions should the nurse take to help this client with tenacious bronchial secretions? 1) Maintaining a semi-Fowler's position as often as possible 2) Administering oxygen via nasal cannula at 2 L/min 3) Helping the client select a low-salt diet 4) Encouraging the client to drink 2 to 3 L of water daily
**4)** Encouraging the client to drink 2 to 3 L of water daily
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The nurse is caring for a patient experiencing an acute exacerbation of chronic obstructive pulmonary disease (COPD). Which of the following medications should the nurse administer first? 1) Tiotropium (Spiriva), an inhaled cholinergic antagonist 2) Salmeterol (Serevent), an inhaled long-acting beta2-agonist (LABA) 3) Albuterol (Proventil), an inhaled short-acting beta2-agonist (SABA) 4) Methylprednisolone (Solu-Medrol), an intravenous corticosteroid
**3)** Albuterol (Proventil), an inhaled short-acting beta2-agonist (SABA)
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The nurse is caring for a patient with acute coronary syndrome (ACS) and atrial fibrillation who has a new prescription for metoprolol. Which data is essential for the nurse to assess prior to administration? 1) Troponin 2) ST segment 3) Heart rate 4) Myoglobin
**3)** Heart rate
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The nurse obtains a rhythm strip on a patient who has had a myocardial infarction and makes the following analysis: no visible P waves, PR interval not measurable, ventricular rate of 162, R-R interval regular, QRS complex wide and distorted, and QRS duration of 0.18 second. How should the nurse interpret this cardiac rhythm? 1) Ventricular tachycardia 2) Ventricular fibrillation 3) Atrial fibrillation 4) Sinus tachycardia
**1)** Ventricular tachycardia
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The nurse is caring for a client who is suspected to have anemia. Which assessment finding does the nurse anticipate? 1) Difficulty sleeping 2) Shortness of breath 3) Chronic headaches 4) Warm hands and feet
**2)** Shortness of breath
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A nurse is monitoring a patient after administering nitroglycerin. Which assessment finding requires the immediate intervention? 1) Heart rate of 82 beats per minute 2) Flushed, warm skin 3) Blood presure 88/48 mmHg 4) Complains of headache
**3)** Blood presure 88/48 mmHg
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What percentage of muscle strength does an healthy individual lose per day while immobilized?
0.03
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How can nurses help prevent impaired tissue integrity?
1) Reduce moisture 2) Nutrition (vitamins A+C, zinc) 3) Reduce sun exposure (hats, long sleeves, sunscreen) 4) Burn prevention (turn down water heater)
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What kinds of interventions do you avoid in impaired tissue?
1) No massaging area (friction and tears) 2) Hot water and soap (burns) 3) Cornstarch (promotes bacterial growth) 4) Briefs (holds moisture)
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What are the four pressure ulcer stages? What is unstageable and suspected deep tissue injury?
Stage 1: **nonblanchable** redness, **intact skin**, sensation changes Stage 2: partial-thickness skin loss, **dermis exposed, pink, moist, red** Stage 3: full-thickness skin loss,** fat visible**, slough/eschar possible, granulation tissue Stage 4: Full-thickness skin loss, **exposed, muscle, tendon, and bone** slough/eschar, tunneling, undermining Unstageable: obscured full-thickness skin loss by eschar/slough Suspected deep tissue injury: nonblanchable, deep red/maroon, skin intact or open
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What are risk factors for pressure injuries?
1) Immobility 2) Decreased sensation/perception 3) Poor nutrition 4) Diabetes or peripheral vascular disease 5) Moisture/incontinence
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How can nurses prevent pressure injuries?
1) Monitor albumin and proterin serum 2) Good nutrition 3) Check perfusion 4) Turn Q2H
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What is the maximum degree for the head of the bed when trying to manage pressure injuries?
HoB should not be higher than 30 degrees
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What lab should you monitor in pressure injury?
Serum albumin
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How are pressure injuries treated?
1) Pain management 2) Dress wound 3) Relieve pressure
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Can you massage or place cold packs on pressure injuries?
No
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How high should the HOB be when eating to prevent aspiration?
45 degrees (High Fowler's)
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What is arthritis?
Inflammation of the joints
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What is osteoarthritis?
- Progressive deterioration and loss of articulating joint cartilage, bone, and connective tissue - Synovial fluid declines = decreased lubrication and nutrition - Associated with pain w/ mobility - Most common in older adults
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What is the brief pathophysiology of osteoarthritis?
1) Enzymes break down articular matrix eroding cartilage and bone 2) Inflammation sets in calcifying, thinning, and ulcerating tissue 3) Cartilage disintegrates causing it to float, creates crepitus (noises)
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What is crepitus?
Grating sound in osteoarthritic joints d/t loosened bone and cartilage in the joint
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The causes of osteoarthritis have primary and secondary types, what are they?
1) Primary OA: age and genetics (mechanical weardown) 2) Secondary OA: joint injury, obesity
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What contributes to osteoarthritis?
1) Manual occupations 2) Excessive use 3) Trauma 4) Joint disease 5) Athletics 6) Metabolic diseases 7) Blood disorders (hemophilia)
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Is osteoarthritis more common in men or women and at what age? What about military personnel?
1) Men under 55 y/o 2) Women over 55 y/o 3) Veterans are 2x more likely to be diagnosed at age 40
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Is osteoarthritis systemic or localized? Unilateral or bilateral?
Localized, unilateral
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What are ways to prevent osteoarthritis?
1) Avoid injury 2) Take breaks at work, especially if it is repetitive tasks 3) Proper nutrition to prevent obesity
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What should nurses assess in osteoarthritis?
1) Pain location and quality 2) Joint stiffness 3) Any swelling 4) Disruption of ADLs 5) Age, gender, work, veteran, weight
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What are the signs and symptoms of osteoarthritis?
1) Stiffness w/ 30 minutes of no activity 2) Severe joint pain that worsens with activity 3) Crepitus 4) Nodules on hands
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In osteoarthritis is pain relieved with activity or rest/sleep?
Pain is relieved by rest/sleep
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How is osteoarthritis diagnosed?
1) MRI 2) Erythrocyte sedimentation rate (ESR) 3) X-ray
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What are the nursing priorities in osteoarthritis?
1) Pain management 2) Decreased mobility d/t pain and atrophy
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What drug therapy can be used in osteoarthritis?
1) NSAIDs like Diclofenac 1% cream = topical NSAID, 2 weeks before effective, avoid heat to area 2) Acetaminophen = 4000mg/day max, **use only 3000mg** d/t liver damage 3) Celecoxib = cox 2 inhibitor; watch out for edema, SOB, dark-tarry stool; not for those with hypertension, kidney disease, or cardio history 4) Corticosteroid injection = reduced inflammation (suppresses immune system, decrease bone density, increase blood sugar, weight gain) 5) Hyaluranic acid = increase lubrication
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What should you monitor for in NSAID use?
Kidney damage, GI bleed (dark-tarry stools), dehydration
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Can NSAIDs be taken with a history of stroke or cardiac history?
No
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What nonpharmacological methods can be used for osteoarthritis treatment?
1) Rest and exercise 2) Hot and cold packs 3) Aquatic exercises 4) Topical capsacin (modified substance P) 5) Glucosamine supplement (reduced inflammation) 6) Proper lifting and posture
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What is the surgical management for osteoarthritis and what are its contraindcations?
1) Total join arthroplasty: total join replacement of all functional parts with a prosthesis (Ex: hip, knee, shoulder, ankle) 2) Contraindications: infection anywhere in the body, hypertension, uncontrolled diabetes, progressive inflammation
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What are postoperative care consideration for osteoarthritis?
1) KEEP LEGS ABDUCTED 2) On surgery day, ambulate them 3) Night after surgery = weight bearing ambulation, 1 week later = full weight bearing 4) VTE prevention = heparin, ambulation 3x/day, heel push, leg extensions, knee pushes
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How does a patient improve osteoarthritis?
1) Exercise after heat is applied 2) Exercise on good and bad days 3) Respect pain 4) Active exercise is best
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What is rheumatoid arthritis, the etiology, and what is it characterized by?
1) A chronic, progressive, and systemic inflammatory autoimmune disease affecting primarily synovial joints; 2) Etiology: environment and genes, stress, infection, but affects women more d/t reproductive hormones 3) Characterized by exacerbations and remissions
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What gender and race does rheumatoid arthritis mainly affect?
2-3x more women than men; mainly white individuals
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What are early versus late signs of rheumatoid arthritis?
1) Early: joint inflammation, low-grade fever, fatigue, weakness, parathesias 2) Late: deformities join joint (swan neck, ulnar deviation), **morning stiffness that lasts longer than 30 minutes**, moderate-severe pain, fatigue, subcutaneous nodules, dry eyes/mouth/vagina
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What are the effects of rheumatoid arthritis?
1) Pain 2) Decreased mobility 3) Decreased self-image
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How is rheumatoid arthritis diangosed?
1) Rheumatic factor 2) HsCRP 3) Anti-CCP 4) Antinuclear antibody 5) Erythrocyte sedemendation rate
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What are the treatments for rheumatoid arthritis?
1) Total joint arthroplasty 2) NSAIDs 3) Disease-modifying antirheumatic drugs (methotrexate and hydroxychloroquine) 4) Biological response modifiers = inhibit inflammatory cytokines 5) Ice + heat application 6) Wax dips
337
How do DMARDs help in RA? When in the disease process should they be used?
1) DMARDs: they slow the progression of RA by reducing joint pain and inflammation. 2) Use: Earlier in the disease process = more effective
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Methotrexate: what is it, how often is it taken, length before effectiveness, adverse effects?
What is it: immunosuppressing drug that works by reducing pain and swelling Taken: once per week Length: Work best earlier in disease course, takes 4-6 weeks before seeing inflammation control Effects: Decrease in WBC or platelets d/t bone marrow suppression, elevated liver enzymes and serum creatinine. Lymph node tumor. Pneumonitis. Mouth sores. Dyspnea.
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What patient education is needed for RA patients taking Methotrexate?
1) Increased infection risk = avoid large crowds and those who are ill 2) Avoid alcoholic beverages becuase of possible liver toxicity 3) Report adverse effects like mouth sores and acute dyspnea 4) Taking folic acid can help decrease side effects 5) Methotrexate use can cuase birth defects, therefore patients who can become pregnant should be on strict birth control. It must be stopped 3 months before pregnancy and cannot be used while breastfeeding.
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Hydroxychloroquine: what is it, what stage of RA does it work best in, side effects, and contraindications?
1) What is it: It is an antimalarial drug that helps suppress the immune response to decrease joint and muscle pain. 2) Stage: Works best in mild RA 3) Side effects: Lightheadedness, stomach discomfort, headache 4) Contraindications: Do not use if present cardiac disease or dysrhythmias
341
What are some mobility interventions that can be given for those with rheumatoid arthritis?
1) Find alternatives for ADLs 2) Replace heavy cup lids and difficult handles 3) Long-handled brushes 4) Shoe horn 5) Handles + grip bars 6) OT consult
342
What is the brief pathophysiology of rhuematoid arthritis?
1) Antibodies (rhuematoic factors) attack healthy synovium causing inflammation 2) Inflammation and immunity factors cause cartilage damage alongside cytokine + WBC attraction 3) Synovium thickens, fluid accumulates in joints, bone fuses and calcifies
343
What are risk factors for Parkinson's disease?
**1)** 50 + **2)** Male **3)** Genetic **4)** Toxin or chemical exposure **5)** Chronic use of antipsychotics
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What are expected findings in Parkinson's Disease?
**1)** Bradykinesia: slowness of movements **2)** Akinesia: difficulty intiating movement **3)** Tremor (pill-rolling) **4)** Gait (Shuffling, festinating) **5)** Muscle rigidity **6)** Stooped posture **7)** Masklike expression **8)** ANS difficulties (swallowing, chewing, mood)
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What are some nursing interventions in Parkinson's Disease?
**1)** Administer meds **2)** Monitor intake (aspiration risk, nutrition) **3)** Sit upright while eating, smaller meals, thickened liquids **4)** OT consult **5)** Exercise **6)** Safe area/fall prevention
346
What are possible treatments for Parkinson's Disease?
**1) Dopaminergic agents:** increase dopamine in BG (Cabidopa prevents levodopa from being broken down) **2) Dopamine agonists:** activate release of dopamine (Bromocriptine, ropinirole) - monitor for orthostatis hypotension **3) Anticholinergics:** block Ach controlling tremor and rigidity (Benztropine) - very drying - mouth, GI, GU
347
What are some complications of Parkinson's Disease?
**1)** Aspiration pneumonia **2)** Altered cognition **3)** UTI **4)** Depression **5)** Skin breakdown
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What are the physiologic consequences of pain?
1) Initiates metabolic proceses (weight loss, tachycardia, increased RR) 2) Higher rates of infection d/t higher cortisol levels 3) Unrelieved pain can lead to pneumonia (shallow breathing) and hypercoagulation leading to MI/stroke. 4) Increased heart rate and blood pressure in acute pain 5) Impaired mobility
349
What pain levels should each analgesic be used for?
1) Nonopoids - mild to moderate nociceptive pain (NSAIDs, acetaminophen) 2) Opioids - moderate to severe pain (Oxycodone, hydrocodone, morphine) 3) Adjuvants - anticonvulsants/antidepressants for neuropathic pain
350
What kind of pain can antidepressants help with? What should you monitor for?
Nerve-related pain, monitor for sedation and suicidal ideation.
351
Why are older adults at risk for dehydration?
1) Low percent body weight as water 2) Decreased thirst response 3) Decreased kidney function
352
What is clinical dehydration?
Loss of water w/o loss of sodium increasing osmolality and decreasing volume
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What is fluid volume deficit?
Loss of both water and electrolytes equally decreasing volume
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What is fluid volume excess?
Too much isotonic fluid increasing volume
355
What causes clinical dehydration?
1) Lack of water intake 2) Lack of thirst response (coma, tube feeding w/o water) 3) GI losses (vomiting, diarrhea) 4) Diabetes insipidous (no ADH = large urine output) 5) Excessive sweating 6) Wound drainage
356
What are symptoms of clinical dehydration?
1) sudden weight loss (1kg (2.2lbs)/day =1L of water lost) 2) dry oral mucosa 3) Low BP 4) High HR 5) High RR 6) Flat veins 7) Oliguria (minimal urine output, dark, less than 500mL/day or 30mL/hour) 8) LOC 9) seizures **10) Na+ increased (>145)** 11) High sodium, high hematocrit, high BUN, high urine specific gravity, high creatinine
357
What are the causes of fluid volume deficit?
1) blood loss 2) GI losses (nausea, vomiting) 3) diuretic treatment 4) lack of aldosterone 5) Altered intake (impaired swallowing) 6) prolonged NPO 7) confusion
358
What are the symptoms of fluid volume deficit?
1) sudden weight loss 2) Low BP 3) High HR 4) Dry mucosa 5) Oliguria
359
What is different between clinical dehydration and fluid volume deficit?
There is no sodium loss in fluid volume deficit
360
What is a consequence of fluid volume deficit and dehydration?
Decreased tissue perfusion leading to low O2 to tissues, shock
361
What is a consequence of fluid volume overload?
Impaired tissue perfusion d/t edema (generalized, pulmonary edema) because capillaries are pushed farther away from cells
362
What is a consequence of clinical dehydration?
Na+ shifts fluid away from cells causing them to shrink leading to LOC, confusion, shock
363
How is clinical dehydration treated?
Isotonic Na+ solution (sodium included to prevent seizures from rapid shifting) and extra water, fall prevention
364
How is fluid volume deficit treated?
Isotonic Na+ solution, monitor, fall prevention
365
What are the causes of fluid volume excess?
1) Excess Na+ isotonic solutions 2) high oral intake of sodium and water 3) Oliguria (CKD) 4) Heart failure 5) IV overload
366
What are the symptoms of fluid volume excess?
1) Sudden weight gain (1kg (2.2lbs)/day) 2) Edema 3) Bounding pulse 4) Dyspnea/SOB 5) Pulmonary edema 6) Distended veins 7) Increased RR and BP 8) decreased Hct, Hgb 9) pale, cool skin 10) lung crackles
367
How is fluid volume excess treated?
1) Fluid/Na+ restriction 2) Elevate HOB 3) Administer O2 4) **Diuretics (Furosemide)** 5) Aquaretics 6) Dialysis
368
Furosemide (Lasix): 1) Type 2) Oral vs. IV 3) Adverse effects 4) Patient teaching
1) Type: It is a loop diuretic that removes water, sodium, and electrolytes (K+) 2) *Oral* onset is 60 minutes and duration is 8 hours; *IV* onset is 5 minutes and duration is 2 hours (rapid intervention) 3) Adverse effects: Ototoxicity (hearing damage), excess Na+/K+/water loss, hypotension 4) Teaching: Slow position changes and eat foods high in potassium or supplement
369
What are the three main causes of electrolyte imbalances?
**1)** Output is greater than intake **2)** Output is less than intake **3)** Altered elecrolyte distribution (i.e., potassium moving into ECF and H+ moving into ICF during acidosis, calcitonin increasing ECF Ca2+ )
370
What are age-related issues in fluid balance regarding skin, kidney, musclar, neurologic, and endocrine?
1) Skin: poor turgor, dry skin 2) Kidney: decreased GFR means less excretion and decreased concentrating capacity increasing water loss 3) Muscular: less muscle mass = less total body water 4) Neurologic: decreased thirst reflex = less fluid intake 5) Endocrine: adrenal atrophy = poor Na+ and K+ balance (low for both)
371
What is obligatory urine output? How much is it?
Obligatory urine output: The minimum output per day to remove toxic waste. Amount: 400-600mL/day
372
What is insensible water loss? How much is typically lost?
Insensible water loss: lost fluid b/c no mechanism controls it (Ex: salivation, perspiration, lung vapor, fistulas, drains, GI suction Amount: 500-1000mL/day
373
What is normal fluid intake per day (mL)?
~2300mL/day
374
What is the stimulus and function of aldosterone?
Stimulus: It is secreted by the adrenal cortex when Na+ ECF levels are low, renin signals release Function: Acts on the kidneys to prevent and Na+ and water excretion by increasing reabsorption
375
What is the stimulus and function of antidiueretic hormone?
Stimulus: Secreted by the hypothalamus and stored in the PP for release when blood osmolarity is too high Function: Inserts aquaporins into the collecting ducts to reabsorb water
376
What is the stimulus and function of natriuretic peptide hormone (NPH)?
Stimulus: Released from the heart atria and ventricles in response to increased blood volume and blood pressure Function: Inhibits Na+ and water reabsorption at the kidneys (works in contract to aldosterone)
377
What are the functions of angiotensin 2?
**Functions:** **1)** constricts ateries and veins to increase total peripheral resistance **2)** Constricts afferent arterioles to decrease GFR and urine output **3)** Stimulates aldosterone output to increase Na+ and water reabsorption
378
Provide the normal value range for sodium, potassium, calcium, magnesium, and typical serum osmolarity:
**Sodium:** 136-145 mEq/L **Potassium:** 3.5-5.0 mEq/L **Calcium:** 9.0-10.5 mg/dL **Magnesium:** 1.3-2.1 mEq/L **Osmolarity:** 270-300 mOsm
379
Hyponatremia: lab value, key issue, causes, symptoms, nurse role, treatment
**Lab value:** <136mEq/L **Key issue:** decreased membrane excitability (need high ECF Na+ to excite) and **cellular swelling** **Causes:** prolonged diuresis, excessive water intake, kidney failure, GI fluid loss, burns **Sx:** *normal volume* = increased HR; *hypovolemic* = thready, weak pulse, rapid HR, hypertension; *hypervolemic* = rapid, bounding pulse, BP normal or elevated -> *cerebral changes (behavioral)* = **LoC, confusion, seizure**, headache -> *Neuromuscular* = weakness, hyporeflexia -> *Intestional* = increased GI motility, nausea, diarrhea **Nursing role:** monitor LoC, extremity strength/reflex, slow position changes, monitor patient's respons to therpy, prevent hypernatremia and fluid overload, **Tx:** IV saline (if deficit), reduce dieuretic dose, **increase Na+ intake**, **hypertonic solution if ECF is low osmolairty**, lithium for SIADH
380
Hypernatremia: lab value, key issue, causes, symptoms, treatment, and nurse role
**Lab value:** >145 mEq/L **Key issue:** increase tissue excitability (Na+ moves more easily into cells), **cells shrink and stop responding** **Causes:** kidney failure, hyperaldosteronemia, dehydration, excessive Na+ intake, IV fluids, steroids, diabetes insipidous **Sx:** *nervous* = altered mental status, **irritable, agitated**, short attention span; *skeletal muscle* = twiching, contractions, weakness + hyporeflexia in severe; *CV*= **edema**, decreased contractility; **other** = skin flushed and dry, thirsty **Nurse:** assess muscle strength with hand grip/arm flexion **Tx:** Restrict Na+ intake, **furosemide** diuretic, **isotonic saline w/ dextrose 5% in .45% sodium to correct imbalance without rapid shifting into cells**
381
Hypokalemia: lab value, key issue, causes, symptoms, treatment, and nurse role
**Lab value:** <3.5 mEq/L **Key issue:** decreased excitability causing nerve and musces cells to be less responsive **Causes:** diuretics (loop + thiazide), corticosteroids, high aldosterone, vomiting, diarrhea, alkalosis, hyperinsulinism **Sx:** respiratory = shallow, **weak respirations** ; skeletal muscle = hyporeflexia, weak grip; CV = weak, thready pulse, orthostatic hypotension; neuro = irritable, anxious, confused; GI = decreased peristalsis, N/V, constipation -> ECG Findings: **Prominent U-wave** , ST depression, inverted T wave **Nurse role:** **Ensure good urine output,** PO K+ with food d/t N/V, adequate gas exchange **(assess respiratory status and heart Q2H)**, prevent K+ admin injury **Tx:** K+ supplements, IV K+ (**DO NOT PUSH, DILUTE INSTEAD; 5-10 mEq/hour)**, self intake (bananas, citrus, raisins, meat), switch to potassium sparing diuretics like **Spironolactone**
382
Can you IV push K+? Can it be given IM or SubQ?
HELL NO. It should be administed via IV infusion, diluted with saline, and administered slowly at 5-10mEq/hour. It cannot be given IM/SubQ.
383
What type of PO K+ can be crushed?
Effer-K can be dissolved in liquid for PO admin
384
Hyperkalemia: lab value, key issue, causes, symptoms, nursing role, and treatment
**Lab value:** >5.0 mEq/L **Key issue:** increases cell excitability causing less response to stimuli, **especially conduction to the heart** **Causes:** high K+ intake (supplements,** salt substitutes**), IV infusion, whole blood transfusions, acidosis, kidney failure, **potassium-sparing diuretics (Spironolactone), ACE Inhibitors (lisinopril - 'prils)** , acidosis **Sx:** *CV=* bradycardia, hypotension, ectopic beats, heart block, asystole, ventricular fibrilation; *neuromuscular=* twitching, **contracting/cramps**, **numbness/tingling of hands/feet/mouth**, weakness starting at extremities; *GI=* increased motility, diarrhea, hyperactive BS -> *ECG:* **Peaked T waves**, prolonged PR, wide QRS **Nurse role**: **assess for any cardiac complications** with continuous monitoring , decrease potassium intake, prevent falls, **Tx:** Patiromer/Kayexelate = bind K+ decreaseing GI absorption, low K+ foods, no supplements, **potassium-excreting diuretics (loop=furosemide or thiazide = hydrochlorothiazide)**; insulin w/ dextrose, dialysis
385
Hypocalcemia: lab value, key issue, causes, symptoms, nursing role, and treatment
**Lab value:** <9.0 mg/dL **Key issue:** Inceased Na+ movement across excitable membranes when there is low Ca2+ = increased depolarization **Causes:** Decreased Ca2+ intake, lactose intolerance, malabsorption syndromes (Chron's/Celiac), low vitamin D intake, diarrhea, alkalosis, CKD, wound drainage, decreased parathyroid hormone **Sx:** *neuromuscular=* muscle twitching, **painful cramps/spasms in thigh/calf,** N/T of hands/feet/lips, **positive Troussea's sign, positive Chvostek** sign; *CV=* **weak respirations** weak, thready pulse, decreased HR and BP; *ECG=* **prolonged QT intervals** ; *GI=* increased bowel sounds, cramping, diarrhea; *skeletal=* osteoporosis **Nursing role:** **decrease environmental stimuli, have emergency trachestomy equipment on standby (d/t laryngospasm)**, careful lifting/moving d/t brittle bones, proper body mechanics **Tx:** Dietary (spinach, kale)/IV Ca2+ replacement, vitamin D
386
Hypercalcemia: lab value, key issue, causes, symptoms, nursing role, and treatment
**Lab values:** >10.5 mg/dL **Key issue:** High Ca2+ causes excitable tissue to be less sensitive = cells needs a stronger stimulus to depolarize **Causes:** Excess Ca2+ intake, excess vitamin D intake, hyperparathyroidism, CKD, thiazide diuretics, immobiltiy **Sx:** *CV=* increased HR and BP in mild and decreased in severe, increased clotting in legs and pelvis, edema; *ECG=* short QT, wide T; *neuromuscular=* weakness, **hyporeflexia**, confusion; *GI=* constipation, decreased bowel sounds, vomiting, **excessive urination** **Nursing role:** **monitor cardiac function,** rehydration with normal saline **Tx:** Stop Ca2+ intake, use normal fluids, **phosphorus/calcitonin/biphosphonates/NSAIDs** to keep Ca2+ in bone, stop/change diuretics **(stop thiazide, start loop)**
387
Hypomagnesemia: lab value, key issue, causes, symptoms, nursing role, and treatment
**Lab value:** <1.3 mEq/L **Key issue:** Increased membrane excitability (magnesium at normal levels helps inhibit) - also **low Mg2+ means low K+ and Ca2+** **Causes:** decreased absorption of dietary Mg2+ (proton pump inhibitors - stop acid = no magnesium chelation, Celiacs/Chron's), Thiazide and loop diuretics, diarrhea **Sx:** CV= **tachycardia, hypertension**, dysrthymias (a. fib, v. fib, long QT); neuromuscular= **hyperreflexia**, N/T, irritability, **positive Troussea's, positive Chvostek, seizures;** GI = nasuea, constipation **Nursing Role:** **monitor cardiac activity,** assess DTR in IV Mg2+ replacement, seizure precuations **Tx:** discontinue diuretics (loop + thiazide), aminoglycosides, magnesium sulfate, IV therapy
388
Hypermagnesemia: lab value, key issue, causes, symptoms, nursing role, and treatment
**Lab value:** >2.1 mEq/L **Key issue:** high Mg2+ causes extreme inhibition and decreased depolarization **Causes:** mangesium-containing antacids/laxitives, IV replacement, CKD/kidney failure **Sx:** **CV = bradycardia, peripheral vasodilation, hypotension, cardiac arrest, respiratory depression**; ECG = wide QRS, prolonged PR; neuromuscular = **absent or reduced DTR**, muscle weakness **Nursing Role:** **monitor cardiac function**, monitor DTR **Tx:** calcium gluconate, stop all Mg2+ products, **loop (furosemide/lasix)**, Mg2+ free fluids
389
What is cell proliferation?
When the body has a physiological needs for more cells (Ex: more WBCs during infection) or after apoptosis
390
What is cell differentiation?
When cells go from immaturity to maturity for a specific function
391
What is contact inhibition? Do cancer cells have contact inhibition?
It is what prevents cells from growing outside their territory. Cancer cells do not have contact inhibition.
392
What are proto-oncogenes and tumor suppressor genes? How do cancer cells benefit from mutations on these?
Proto-oncogenes: regulate and promote cell growth Tumor supressor genes: regulat and suppress cell growth Cancer cells benefit becuase mutations will either inactive tumor suppressor genes or overactivate proto-oncogenes.
393
What is a cancer or malignancy?
Abnormal cell growth which new tissues grow unregulated harming normal cell function
394
What are the three steps to cell transformation to cancer?
1) Initiaion: lose regulation, irreversible 2) Promotion: enhanced growth by endogenous hormones or other substances 3) Progression: increased growth and can be detected, **has own blood supply**
395
What is cancer grading?
How similar cancer cells look like parent cells
396
What is cancer staging?
How progressed is the cancer? Informes prognosis, tx, and options. Tumor-node metastasis (TNM): 1) Location 2) Size 3) Lymph spread 4) Spread to distant points
397
What cancers have the highest death rate and higest incidence?
**Death:** Lung + Bronchus **Incidence:** Prostate (men), breast (women)
398
What are the three main cancer risks? What accounts for the most causes?
1) Carcinogen exposure = responsible for 90% of cancer 2) Genetics 3) Immunity (reduced immunity d/t **age**, infection, transplant, medications) - age is a risk because exposure accumulates
399
What is cachexia?
Cachexia: malnutrition and extreme body wasting caused by cancer becuase it steals nutrients that cells need
400
Describe the following cancer treatment modalities: * Prophylactic * Diagnostic * Curative * Debulking * Palliative * Reconstructive
1) **Prophylactic:** tissue removal to prevent cancer (i.e. mastectomy) 2) **Diagnostic:** removal of all or part of lesion to test 3) **Curative:** remove all cancerous tissue, cure 4) **Debulking:** partial tumor removal to improve symptoms, improve other treatment, and increase survival time 5) **Palliative:** symptom relief and impove quality of life 6) **Reconstructive:** increase function and/or appearance
401
What treamtent strategies are used in cancer?
1) **Monotherapy:** single treatment modality used 2) **Combination:** two or more treatments used together 3) **Maintenance:** continued treatment to prevent cancer recurrence and progression 4) **Experimental:** clinical trials for a new treatment
402
What is radiation therapy and where does it affect tissue?
Radiation therapy is using high-energy radiation to kill cancer cells for curative or palliative treatment. Effects are only seen in the target area.
403
What are protective measures nurses should do when workin with radiation therapy?
1) Reduce time in field 2) Increase distance from field 3) Use shielding (lead apron/shield) 4) Use dosimeter
404
What are the two types of radiation therapy?
1) External beam: radiation is outside of patient, they are not radioactive (IMRT, stereotactic, radiosurgery) 2) Brachytherapy: internal radiation, object placed direct in contact with tumor or ingested giving a higher dose. Patient is only radioactive while the seed is still in
405
What are some symptoms of radiation therapy?
1) Radiation dermatitis: redness pigmentation, desquamation 2) systemic: fatigue, altered taste, bone marrow suppression 3) Fibrosis and scarring 4) Secondary malignancies 5) N/V 6) Photosensitive skin
406
Why should radiation patients stay out of the sun?
Because their skin becomes photosenitive increasing sunburn risk. They should avoid sun during and 1 year after radiation is complete.
407
What should nurses educate patients about their skin during radiation?
1) Wash area with mild soap and water 2) **No scrubbing** 3) Do **not** remove ink tattoo until radiation therapy is complete
408
What is systemic cancer therapy? What is important to know about the systemic aspect?
The use of antineoplastic (chemo) or immunotherapy drugs to kill cancer and disrupt regulation of cancer cells. It kills both healthy and cancerous cells. Types: Chemo, immunotherapy, hormone (endocrine), and targeted therapy
409
What is immunotherapy in cancer?
Therapy that works to activate the immune system to attack cancer cells
410
What is neoadjuvant chemo?
Chemo used **before** surgery/radiation to debulk or shrink the tumor
411
What is adjuvant chemo?
Chemo used **after** radiation/surgery
412
Is treatment of metastatic cancer curative?
No, but it can help increase survival time
413
Why should the nurse emphasize proper adherence to the chemo/immunotherapy schedule?
The schedule must be followed to achieve the best dose in order for the best response
414
Chemo drugs are considered vesicants. What is a vesicant and what should you assess/do?
Vesicant: medication that is damaging to tissue on direct contact Assess IV site and stop infusion if s/s appear.
415
Are oral chemotherapy drugs as toxic as IV drugs?
Yes
416
Can oral chemotherapy drugs be crushed, split, or broke?
No
417
Are patients allowed to touch oral chemotherapy medications with their bare hands?
No, they should use a glove.
418
What should a patient do if they miss their chemotherapy dose?
Do not double up, take the next dose when scheduled
419
What are symptoms of chemo?
1) Cardiac muscle damage 2) Decreased bone density 3) Anemia 4) Reduced immunity 5) Neutropenia 6) Thrombocytopenia 7) Reduced clotting 8) N/V 9) Mucositis 10) Alopecia
420
What is the greatest dose-limiting symptoms/effect of chemo?
Bone marrow suppression d/t concern of reduced immunity
421
What are some neutropenic precuations?
1. Handwashing or alcohol-based rubs before contact 2. Clean their room and bathroom 1x/day 3. Place patient in private room 4. Vitals Q4H 5. Monitor IV sites 6. Inspect mucus membranes and skin 7. Restrict sick visitors 8. Change wound dressings daily 9. Notify provider of any possible infection 10. Keep equipment in patients room 11. Monitor WBC daily 12. Avoid catheter use 13. Avoid potted plants/flowers in the room
422
What are low WBC precuations for patients?
1) Avoid crowds 2) no sharing toiletries 3) bathe daily 4) use antimicrobial soap 5) do not drink standing liquids 6) do not clean up after pets
423
What is an emetogenic?
Vomit inducing substance/agent
424
When are antiemetics given for chemo to work best?
Before chemo is best but can also be given at first s/s
425
Describe the following types of chemotherapy-induced N/V: * Anticipatory * Acute * Delayed * Breakthrough
* Anticipatory: before receiving chemo, triggered by thoughts, sights, sounds * Acute: w/in 24 hours of receiving chemo (i.e. Decarbazine) * Delayed: after first 24 hours (Cisplatin) * Breakthrough: intermittent
426
Ondansetron (Zofran): Use, MoA, route, when to use, side effects
Use: Treat nasuea and vomiting, antiemetic MoA: serotonin antagonist blocking the H-HT3 receptors in brain and GI. Route: Oral or IV When: 1-2 hours before chemo Side effects: headache, orthostatic hypotension, bradycardia, vertigo, constipation, porlonged QT interval
427
Prochlorperazine (Compazine): Use, MoA, route, side effects
Use: Nasuea and vomiting, antiemetic MoA: dopamine (D2) antagonist in the brain Route: Oral Side effects: drowsiness, extrapyramidal reactions, difficulty cooling body
428
What is mucositis and how can it allieved?
Mucositis: inflammation of the oral and GI mucosa Relieved: gentle flossing, non-alcoholic rinses, brush every 8 hours, drink 2L of water daily, avoid spicy and acidic food
429
What is alopecia and how should you protect your scalp?
Alopecia: hair loss Protection: use sunscreen and coverings
430
How soon after chemotherapy does hair regrow?
Hair regrowth begins ~1month after stopping chemotherapy
431
What is "chemo brain"
Decline in concentration and memory during chemo
432
What is chemo-induced peripheral neuropathy?
It is peripheral neuropathy caused by damage to the nerves in extremities, especially lower extremities cuasing gait and balance issues, loss of sensation in hands and feet, orthostatic hypotension, erectile dysfunction, pain, constipation, and reduced taste
433
What is time toxicity in chemotherapy?
The time and energy one spends on everything cancer-related: treatment, managing care, driving, waiting, fatigue and side effects of treatment
434
What is immunotherapy and its symptoms? Why may it be preferred to chemo?
Immunotherapy: medication used to activate the body's own immune system to detect and attack cancer cells. Sx: fatigue, rash, increased infection risk Preference: It may be preferred over chemo because there are less cytotoxic effects.
435
What is immune-related adverse effects of immunotherapy and how is it treated?
Immune-related adverse events: It is when the immune system stimulation affects healthy cells too causing systemic inflammation (hepatitis, pancreatitis, colitis, etc.) Tx: corticosteroids
436
What is targeted therapy in cancer treatment and what are the symptoms?
Targeted therapy: The use of medications to block growth and spead by interfering with growth and regulatory pathways. For instance, blocking VEG-F acting directly on cancer cell Sx: GI disturbance, decreased immunity, skin rash, hypotension
437
What happens if cancer cells do not express the protein or mutation when undergoing targeted therapy?
The therapy will not work if the protein or mutation is not expressed.
438
What is endocrine therapy and associated symptoms in cancer treatment?
Endocrine therapy: aromatase inhibitors, GRH analogs, antiandrogens, and antiestrogens to prevent cancer cells from receiving growth stimulation Sx: fatigue, orthalgia (joint pain), bone pain, hot flashes, sexual dysfunction, osteoporosis, thrombosis
439
What is the second most deadly type of cancer?
Colorectal cancer
440
Where is colorectal cancer found most often and what is the most common metastasis site?
Found: Rectosigmoid area Metastasis: Most often spreads to the liver
441
What are colorectal risk factors?
1) 50 y/o 2) Genetic predisposition or family history 3) First degree relative = 2-3x risk 4) Familial adenomatous polyposis (FAP) = polyp have 100% chance of becoming cancerous 5) Inflammatory GI issues = Chron's, Ulcerative colitis 6) Personal factors (smoking, alcohol use, physical inactivity, high red meat intake)
442
When is colorectal cancer screening recommended? What kinds of tests?
Age: Beginning at age 45 Tests: stool-based testing, fecal-occult blood testing, multi-targeted stool DNA, colonoscopy, sigmoidoscopy
443
What are ways to prevent colorectal cancer?
1) Increase fiber intake 2) Decrease fat intake 3) Increase vegetables 4) Reduce smoking and drinking
444
What are signs of colorectal cancer?
1) Rectal bleeding 2) Anemia 3) Change in stool consistency 4) Change in stool shape
445
What is the definitive diagnostic test for colorectal cancer?
Colonocopy: viewing entire large bowel
446
What are some nonsurgical interventions in colorectal cancer treatment?
1) Rectal radiation 2) Palliative radiation 3) Adjuvant chemo 4) Bevacizumab: angiogenesis inhibitor, blocks VEG-F 5) Intrahepatic chemo: with 5-fluororacil for liver metastasis
447
What are the two surgical options for colorectal cancer treatment?
1) Colon resection: removal of part of the colon and surrounding lymph nodes 2) Abdominoperineal resection: remove part of the sigmoid colon, rectum, and anus via abdominal + perineal incisions
448
What are some colostomy management recommendations/education?
1) Begins functioning 2-3 days post-op 2) Empty at 1/3-1/2 full 3) Avoid flatus foods 4) Cleans stoma before appliance 5) Should be pink, moist, and 1-3cm tall
449
What are pain management recommendations after colorectal surgery?
1) NO straining 2) soak in sitz bath for 10-20 minutes 3-4x/day 3) analgesics 4) side-lying 5) avoid sittin for long periods and use foam pads 6) avoid using air rings and rubber donuts
450
Acidosis risk factors:
1) older adults 2) Those with breathing dificiluties (COPD, asthma) 3) Kdiney failure 4) Diabetes melitus 5) Diarrhea (bicarb loss) 6) Pancreatitis (bicarb loss) 7) Fever 8) Heavy exercise
451
Metabolic Acidosis: Labs, symptoms, nurse role, treatment
**Labs: ph less than 7.35;** PaO2 (80-100mmHg), PaC02 (35-40mmHg), **HCO3 (less than 15-20)** **Sx:** cardiac = tachy and increased CO early on, **hypotensive and brady later** with wide QRS complex; **CNS = depression of CNS function, lethargy, confusion**; neuromuscular = hyporeflexia, flaccid paralysis; respiratory = **Kussmal respirations**; integumentary = warm, flush, dry skin - cognitive changes may be first seen **Nurse role:** akways **assess CV system first d/t hyperkalemia risk** (H+ ions are exchanged into ICF for K+ into ECF) **Tx:** hydrate low and slow to avoid edema, bicarbonate, antidiarrheals, insulin for DKA
452
Respiratory Acidosis: Labs, symptoms, nurse role, treatment
**Labs:** **pH less than 7.35**; PaO2 (less than 90mmHg); **PaCO2 (>50mmHg);** HCO3- (21-28+) **Sx:** CV= Tachy and high CO early, hypotension and bradycardia with wide QRS complex later on; CNS= depression of CNS w/ **lethargy and confusion**; neuromuscular= hyporeflexia; **integumentary= pale to cyanotic skin** **Nurse role**: always **assess CV system first d/t hyperkalemia risk,** monitor accessory muscle use, breath sounds, cyanosis, monitor lung sounds **Tx:** oxygenation = bronchodilators, antiinflammatories, mucolytics, O2 therapy, mechanical venitlation
453
Causes of metabolic alkalosis?
**1) Increased bases**: Antacid use, blood transfusion, sodium barb, TPN **2) Decreased acids:** vomiting, NG suction, hypercortisolism, hyperaldosteronism, thiaizde diuretics
454
Causes of respiratory alkalosis?
**1) Excess CO2 loss:** hyperventilation, mechanical ventilation, salicylate overuse (too much aspirin stimulating medulla), high altitude
455
Nursing interventions for respiratory alkalosis?
1) Breathe into paper bag 2) Calm reassurance if hyperventalation is due to panic or fear 3) Supplemental O2 as needed
456
Nursing interventions for metabolic alkalosis?
1) Administer fluids as prescribed 2) Administer electrolyte replacement if prescribed
457
What are the symptoms of respiratory/metabolic alkalosis?
Think of hypokalemia and hypocalcemia symptoms! **CNS:**diziness, agitation, confusion, hyporeflexia, N/T in hands/feet/mouth, positive Trousseau's and Chvostek signs **Neuromuscular:** cramps, twitches, "charlie horse", tetany **CV:** tachycardic, thready pulse, digoxin sensitivity **Respiratory:** hyperventilation (respiratory), decreased RR effort (metabolic)
458
Treatment for alkalosis?
1) Redhydrate w/ IV electrolytes 2) Stop suctioning 3) Stop loop/thiazide dieuretics 4) Antiemetics
459
What are some differences between acidosis and alkalosis?
**Acidosis:** hyperkalemia, hyporeflexia, muscle weakness/paralysis, **Alkalosis**: hypokalemia, hyperreflexia, muscle cramps/twitching
460
Hyperthyroidism: what is it, lab levels, symptoms, nursing interventions
**1) What is it:** a hypermetabolic state related to increased T3 and T4 hormones **2) Labs:** High T3+T4, low TSH **3) Sx:** tachycardia, hypertension, hyperglycemia, warm, sweaty, heat intolerance, exopthalmos (bulging eyes), goiter (bulging of thyroid gland), irritable, nervous, fine/soft hair **4) Nursing interventions:** promote calm environment, encourage rest, I/O's and weight, monitor nutrition, decrease room temp, cool showers, report any 1 degree increases in temperature, montior for thyroid storm, monitor vitals, monitor mental status
461
What is thyroid storm?
It is a severe and life-threatening complication of hyperthyroidism where heart rate increase and temperature spikes dramatically, which may lead to coma and possibly death
462
Are you able to palpate a goiter?
No, you should not palpate goiter as it can lead to thyroid storm.
463
Methimazole: what is it, what is it used for, monitor for, patient education
**1) What is it:** it is an drug that blocks iodine from binding in the thyroid gland reducing T3+T4 release **2) Used for:** It is used to treat hyperthyroidism **3) Monitor for:** liver toxicity, hypothyroidism **4) Patient education:** It can suppress your immune system and increase your risk for infection = avoid crowds and those who are ill; symptoms such as weight gain, cold intolerance, and slow heart rate may indicate hypothyroidism indicating the dose needs to be lowered; lastly, women who become pregnant should stop taking this drug and contact their provider d/t birth defect risks
464
Hypothyroidism: what is it, lab levels, symptoms, nursing interventions
**1) What is it:** inadequate thyroid hormone decrease metabolic system activity **2) Lab levels:** low T3+T4, high TSH **3) Sx:** Fatigue, excess sleeping (up to 16 hours and still feeling tired), cold intolerance, constipation, weight gain w/o calorie increase, pallor, brittle nails, depression, bradycardia, hypotension, hair loss, dry ksin, myxedema, hoarseness **4) Nursing interventions:** vital signs and **chest pain**, monitor weight, **monitor mental status changes**, increase activity slowly, avoid laxatives which may interfere with meds, hypothyroidsm decrease medication metabolism = be careful with meds becoming toxic, **monitor respiratory status,** increase room temp/extra blankets
465
Levothyroxine: what is it, what is it used for, monitor for, patient education
**1) What is it:** it is a thyroid replacement medication becuase it acts as a T4 analog **2) Used for:** hypothyroidism **3) Monitor for:** chest pain, dyspnea, hyperthyroidism **4) Patient education:** take 1 hour before meals with water on an empty stomach; avoid taking iron, calcium, and antacids within 4 hours of taking levothyroxine as they decrease absorption; may increase insulin needs and other meds
466
Hypercortisolism (Cushing's): What is it, symptoms, nursing role
**1) What is it:** excess adrenal hormones like cortisol, aldosterone, androgens, and estrogens **2) Sx:** weakness, fatigue, join pain, decreased libido, thin/fragile skin, increased HR and BP, weight gain, increased appetite, bone pain (fracture risk), hyperglycemia, extreme muscle wasting, truncal obesity, buffalo hump, moon face, hypernatremia, hypokalemia, hypocalcemia **3) Nursing actions:** I/O's and weight daily, hypervolemia s/s (edema, SoB, high BP/HR), safe environment d/t fracture risk, meticulous skin care, handwashing, antiseptic dressing changes
467
Hypocortisolism (Addison's): What is it, symptoms, nursing role
**1) What is it:** adrenal insufficiency lacking in cortisol and aldosterone creating a rapid and acute crisis **2) Sx:** salt craving, weight loss, hyperpigmentation of skin (bronzing), N/V, anorexia, low BP, hypovolemia, hyponatremia, hypoglycemia, hyperkalemia, hypercalcemia **3) Nursing role:** prevent circulatory shock, monitor fluids and electrolytes, saline infusions to restore volume, hydrocortisone IV bolus + continuous infusion, monitor and treat hyperkalemia, hypoglycemic management, safe environment
468
What is the risk in an Addisonian crisis?
Priority is to assess for circulatory shock (low BP, LoC down)
469
What is the normal range for fasting glucose?
74-106 mg/dL
470
What is the diagnosis for diabetes (A1C, fasting BG, GTT, random BG)
**1) A1C:** greater than 6.5% OR **2) Fasting BG:** greater than 126 mg/dL OR **3) 2-hour GTT:** greater than 200 mg/dL OR **4) Random BG:** greater than 200 mg/dL WITH hyperglycemis symptoms
471
What are the classic symptoms of hyperglycemia?
**1) Polyuria** = osmotic diuresis d/t high glucose **2) Polydipsia** = thirst d/t fluid loss and high osmolatiry **3) Polyphagia** = increased hunger as body struggles to use glucose **4) Fatigue** = d/t inadequate glucose utilization and energy production
472
What is the recommended amount of exercise for primary prevention of diabetes?
150 minutes of aerobic exercise per week
473
Type **1** diabetes: what is it, cause, risk factors, symptoms, treatment
**1) What is it:** autoimmune destruction of beta cells of pancreas creating a lack of insulin causing the body to be unable to move glucose into its cells (thinks it's starving) **2) Cause:** autoimmune **3) Risk factors:** family history, age (kids, teens, young adults) **4) Sx:** polyuria, polydipsia, polyphagia - abrupt onset of these **5) Tx:** lifelong insulin use
474
Type **2** diabetes: what is it, cause, risk factors, symptoms, treatment
**1) What is it:** peripheral tissue insulin resistance with impaired insulin secretion d/t beta cell exhaustion **2) Cause:** unknown, genetic **3) Risk factors:** obesity, poor diet, physicaly inactivity, family history, medications, environment **4) Sx:** polydipsia, fatigue, blurred vision, dry/warm skin
475
What are the symptoms of hypoglycemia? How is hypoglcyemia managed (treatment and nursing role)?
**1) Sx of hypoglycemia:** weakness, fatigue, sweaty (clammy), tremulous/shaky, anxious, decreased/loss of consciousness, cold **2) Treatment:** **A.** If BG is less than 70 mg/dL, give 15g of **fast acting simple carbs**; if below 50 mg/dL give 30g of fast acting simple carbs. -> **if conscious:** 4oz juice/soda, tbsp of honey, 3-4 glucose tabs, 5 hard candies -> **if unconscious: nothing by mouth**, IM glucagon, IV dextrose **B.** After carbs given, recheck BG in 15 minutes. If still hypoglycemia, repeat simple carbs. **C.** Once BG is above 70 mg/dL and no s/s of hypoglycemia present, provide a snack of **complex carbs** **3) Nursing role:** obtain IV access, provide O2 (only if below 90%), no oral anything if they are unconscious/altered, recheck BG every 15 minutes, check neuro status
476
What is glucagon?
It is a hormone that prevents hypoglycemia by triggering the release of glucose from storage in liver and skeletal muscle. It has the opposite action of insulin.
477
What is the first-line treatment for hypoglycemic patients who are unconscious? Why are they turned on their side? When should glucagon be readministered?
**1)** IV/nasal glucagon **2)** They are turned on their side b/c it can induce vomiting **3)** Readminister if the patient is still unconscious after 10 minutes
478
What are ways to prevent hypoglycemic episodes?
**1)** Check insulin before administering (miscalculation) **2)** Keep regular timing of food intake **3)** Do not exercise while insulin is peaking **4)** Monitor exercise/activity as it can cause BG drop even hours later **5)** Do not exercise if ketones are present (indicates insulin is insufficient, raise BG above 100 mg/dL) **5)** Avoid alcohol - it inhibits liver glucose production causing hypoglycemia. If you want to drink, drink with meals.
479
What are diabetic complications? Describe them.
**1) Eye + vision problems like retinopathy** d/t vessel blockage, leakage, and retinal hypoxia and edema increasing pressure in the eye. This causes glaucoma too. **2) Peripheral neuropathy causing burning, tingling, pain, loss of sensation** d/t hyperglycemia reducing O2 and nutrient delivery leading to nerve hypoxia and decreased transmission **3) Diabetic autonomic neuropathy** d/t hyperglycemia affecting the SNS and PSNS causing orthostatic hypotension, gastroporesis and constipation, N/V, heartburn, early satiety, and urinary urgency and incontinence **4) Diabetic nepropathy** d/t hyperglycemia and hypertension harming nephrons causing albuminuria and decreased GFR later on **5) Sexual dysfunction** such as ED, retrograde ejaculation, decreased lubrication, and painful intercourse **6) Cognitive dysfunction** d/t hyperglycemia harming neurons leading to atrophy
480
What are three medications used to lower blood glucose in diabetes melitus?
**1)** Biguinides (Metformin) **2)** GLP-1 agonist (semaglutide - Ozempic) **3)** Sulfonylureas (Glipizide, Glimepiride)
481
Metformin: class of medication, MoA, adverse effects
**1) Class:** Biguinides **2) MoA:** lowers blood glucose by inhibitng liver glucose production (also reduces intestinal absorption and increase insulin sensitivity) **3) Adverse effects:** do not take with alcohol (hypoglycemia and lactic acidosis risk); **hold 24 hours before contrast** and surgery (kidney damage risk); GI upset like **diarrhea (most common)** and N/V - take it with food to reduce GI discomfort
482
Semaglutide (Ozempic): class of medication, MoA, adverse effects
**1) Class:** GLP-1 agonists **2) MoA:** increase insulin secretion, decreases glucagon secretion, reduces appetite **3) Adverse effects:** pancreatitis (s/s abdominal pain, nausea)
483
Glipizide: class of medication, MoA, adverse effects
**1) Class:** Sulfonylureas **2) MoA:** lowers BG by triggering release of insulin from beta cells (may also increase insulin sensitivity and decrease hepatic glucose production) **3) Adverse effects:** Can cause **hypoglycemia (take with meals)**, check with pharmacist before over the counter drug use d/t multiple interactions; **absolutely no drinking (hypoglycemia and disulfide-like reactions = severe vomiting)**
484
Can other insulin be mixed with insulin glargine or detemir?
No, rapid, short/regular, and intermiediate (NPH) should never be mixed with long acting or premixed insulin formulations.
485
How soon before eating should insulin lispro/aspart/glulisine be administered? How soon before eating should insulin regular/short be administered?
**Rapid acting:** 10 minutes before because it is rapid acting **Short/regular acting:** 30 minutes before eating
486
Provide the onset, peak, and duration of rapid, short/regular, intermediate (NPH), and long acting insulin.
**Rapid:** 10-30 min onset, .5-3hr peak, 3-6hr duration **Regular:** 30-60 min onset, 1-5hr peak, 6-10hr duration **Intermediate:** 1-2hr onset, 6-14hr peak, 16-24hr duration **Long:** 1-2hr onset, no peak, 12-24hr duration **Ultra-long:** 30-90min, no peak, 24hr duration
487
What are insulin storage and administration recommendations?
**1)** Only give subQ, preferrably in the abdomen 2cm away from umbilicus **2)** Refridgerate unopened insulin **3)** Keep insulin out of direct sunlight **4)** Keep opened insulin at room temperature, cold insulin hurts to administer **5)** Wash your hands before testing **6)** Inspect vials and pens before using, should not be clumpy and only NPH should be cloudy **7)** Do not reuse strips or lancets **8)** Use fingertips to test
488
What are important points about **foot care** in diabetes melitus to prevent complications?
**1)** Examine feet daily **2)** Use a mirror to examine sole of foot **3)** Inspect between toes **4) Do NOT** treat blister, sores, or infections at home (don't treat anything yourself) **5)** Do not wear sandals **6)** Wash feet with water and dry thoroughly **7)** Wear clean socky daily **8)** Trim nails straight across **9)** No moistureizer between toes **10)** Wear a different pair of shoes daily **11)** Do not go barefoot
489
What are important points about **nutrition** in diabetes melitus to prevent complications?
**1)** Eat 25g of fiber daily **2)** Eat legumes, vegetables, fruits, whole grains, dairy in place of empty calories **3)** If drinking, men should drink 2 drinks and 1 for women, **drink with meals** **4)** 1 unit of rapid acting insulin for 15g of carbohydrates **5)** 10-15g of carbohydrates per hour of moderate to intense physical activity **6)** Limit trans fats, saturated fats, cholesterol **7)** Keep a routine eating schedule with a similar amount of food **8)** Registered dieticians can help create a personalized meal plan and provide education
490
What are important points about **exercise** in diabetes melitus to prevent complications?
**1)** Avoid intense exercise in retinopathy, autonomic neuropathy, and peripheral neuropathy **2)** Wear proper footwear and inspect feet daily for peripheral diabetes **3)** Regular exercise can help prevent T2DM by increasing insulin sensitivity, reducing body weight and glucose intolerance **4)** Warm up first with low intensity sessions and should have a cool down session too; both 5-10 minutes long **5)** 150 minutes of aerobic activity per week and avoid going longer than 2 days without any activity **6)** Do not exercise when urine ketones are high **7)** Check BG before, at intervals during, and after exercise **8)** BG shoud be above 100 mg/dL before exercise **9)** Do not exercise during insulin peaks
491
What are important points about **sick days** in diabetes melitus to prevent complications?
**1)** Monitor blood glucose every 2-4 hours **2)** Continue taking your insulin or other antidiabetics - **do not omit insulin during illness** **3)** Drink 8-12 ounces of sugar-free liquids every hour your awake, 2L daily **4)** Continue to eat meals at regular times **5)** Notify your health provider that you're ill **6)** Test your urine for ketones to ensure they're in range, especially if you're vomiting **7)** Call your provider if you expierience: persistent N/V, hypoglycemia, moderate-high ketones, fever (101.4+), sick for longer than 1-2 days
492
Diabetic Ketoacidosis (DKA): what is it, diagnosis, which type of diabetes most common in, pathology, causes, symptoms, treatment.
**1) What is it:** rapid onset, life-threatening complication of diabetes caused by severe hyperglycemia, ketosis, metabolic acidosis, and a lack of insulin **2) Diagnosis:** BG = greater than 300 mg/dL, pH = less than 7.35, elevated ketones, elevated BUN/creatinine, low bicarbonate (less than 15 mEq/L) **3) Most common in:** Type 1 diabetes **4) Pathology:** infection or insufficient insulin -> hyperglycemia -> osmotic diuresis -> glucose in urine, dehydration, and electrolyte imbalance **5) Causes:** infection, lack of insulin, stress **6) Sx:** urine ketosis, acetone/fruity breath, kussmal breathing, respiratory alkalosis, polydipsia, polyuria, polyphagia, N/V, dehydrated, high HR, hyperkalemia, abdominal pain **7) Tx:** IV fluids, IV insulin, electrolyte replacement, address underlying cause, supportive breathing
493
Hyperglycemic Hyperosmolar Syndrome (HHS): what is it, diagnosis, which type of diabetes most common in, causes, symptoms, treatment.
**1) what is it:** gradual onset which turns into a hyperglycemic emergency characterized by **profound dehydration,** hyperosmolatiry, but **no ketoacidosis** becuase insulin secretion is enough **2) Diagnosis:** BG = great than 600 mg/dL, serum osmolarity = greater than 320 mOsm, pH = greater than 7.4, higher bicarbonate (above 20), high BUN/creatinine **3) Most common in:** Type 2 diabetes **3) Causes:** infection, stress/illness, poor fluid intake **4) Sx:** hyperglycemia, polyuria, polydipsia, **dry mucus membranes**, high HR, hypotension, **neurologic symptoms like confusion and lethargy into coma** **5) Tx:** aggressive **rehydration (main priority)**, insulin therapy, electrolyte replacement, address underlying cause
494
What is the priority assessment in HHS and DKA?
Adequate perfusion related to fluid volume deficit d/t osmotic diuresis. Hyperkalemia may take priorty in DKA if there are cardiac problems
495
What is autoregulation in intracranial regulation?
The adjustments in blood flow depending on metabolic needs of the brain or BP changes
496
What is the Monro-Kellie Doctrine? What ICR component is the first to change for compensation?
**MKD:** The sum of all cranial volumes, brain, CSF, and BP should remain constant, but can adapt if one changes. **CSF is the first to change in order to compensate** becuase we don't want to alter blood flow
497
Who are the main risk populations for dysregulated ICR?
**1)** Older adults (degenerative conditions, falls) **2)** Young adults and adolescents (risky behavior, MVA) **3)** Children (falls)
498
What subjective history should you obtain when investigating increased ICP or general intracranial regulation?
**1) Level of consciousness** **2) Unexplained headaches** **3)** Other neuro s/s like N/T, dizziness, confusion, **vision changes** **4)** OLD CARTS (pain assessment)
499
What is the main priority in disrupted intracranial regulation?
Balancing ICP
500
What is the collaborative management for intracranrial regulation (priority assessment, decreasing ICP via medications, surgery, and nursing intervention)?
**1)** Priority one is ongoing assessment **2)** Decrease ICP if high by having the HOB @30 degrees and proper head+neck alignment. **3) Pharmacotherapy:** **IV Mannitol** (osmotic diuretic) to pull fluid off, sedatives like **Propofol** to decrease metabolic demand **4) Surgical:** craniotomy, shunt, drain
501
What is the priority nursing roles in strokes?
**1) Restore perfusion to the brain** **2)** CT to determine stroke type and cause **3)** Neuro exam
502
What is stroke prevention (ABCS)?
**A:** Aspirin **B:** Blood pressure management **C:** Cholesterol management **S:** Smoking cessation
503
What heart dysrhythmia can cause emboli?
A. fib
504
Ischemic stroke: what is it, onset, risk factors, level of consciousness, seizure presence, symptoms
**1) What is it:** The occlusion or blockage of a cerebral or carotid artery by thrombus or emboli causing decreased or lack of perfusion **2) Onset:** gradual (thrombic), sudden (embolic) **3) Risk factors:** atheroscerolsis, emboli, hypertension, obesity, diabetes melitus, smoking, drug and alcohol abuse, oral contraceptive use **4) LoC:** awake **5) Seizure presence:** no seizures **6) Sx:** dysphasia, muscle weakness, facial drooping, difficulty with walking (gait, balance), slurred speech, headache, trouble seeing **7) Tx:** fibrinolytic (Alteplase - TPA), craniotomy, shunt
505
Alteplase: what is it, timeframe for use, blood pressure requirement, what to check before administration, checks after administration, other
**1) What is it:** a fibrinolytic, tissue plasminogen activator, that converts plasminogen to plasmin to lyse fibrin and fibrinogen breaking down clots **2) Timeframe:** 3-4.5 hours (after 3 hours there are special requirements) **3) BP:** must be below 185/110 - if above, antihypertensives must be given first (IV Labetolol) **4) Checks before admin:** confirm **onset** and timeframe of symptoms, Blood glucose (hypoglycemia can mimic stroke symptoms), K+ levels (it can lower K+), check pH (acidosis), weight (dosing is by weight), pregnancy (harm to fetus), any surgery within the past 14 days **5) Checks after admin:** hold anticoagulants (no Heparin, aspirin, etc.) for 24 hours, monitor vitals, monitor BG to prevent stroke complications, consult hematology to increase PT and INR
506
Hemorrhagic stroke: what is it, onset, risk factors, level of consciousness, seizure presence, symptoms, treatments
What is it: The interruption of vessel integirty cuasing bleeding into the brain tissue or subarachnoid space Onset: abrupt, sudden Risk factors: hypertension, cochise and alcohol use, obesity, diabetes LoC: decreased Seizure: yes Sx: severe, unrelieving headache, blurry vision, seizure, decreased LoC, difficulty walking, dysphasia Tx: antihypertensive, craniotomy, shunt
507
What history is necessary in stroke assessment?
**1) Symptom onset (when**) **2)** Abrupt or slow onset **3)** Any improvement **4)** Medications (blood thinner, antihypertensives, contraceptives) **5)** Social diet (food, alcohol, smoking) **6)** Drug use (cocaine especially)
508
What is the diagnostic standard in strokes?
CT imaging such as CTP (computerized tomography perfusion) and CTA (computerized tomography angiography)
509
What are important post-stroke considerations?
**1)** They should remain NPO until swallowing can be assessed **2)** Help with ambulation, they are a fall risk d/t neuro status and blood thinners **3**) Thickened liquids to prevent aspiration **4)** High fowlers when eating **5)** No straws **6)** Electric razor not straight razor to prevent bleeding **7)** Have suction available for aspiration **8)** Discontinue combined birth control **9)** Oral care continues even if NPO **10)** Toileting Q2-3H
510
What side do you approach a stroke patient from, but which side do you start interventions with?
Approach from their unaffected side but start with their affected side.
511
Compare left- and right-sided brain damage d/t stroke:
**Left-sided damage:** right-sided paralysis, more cautious, apprehensive, anxious, needs encouragement, impaired speech **Right-sided damage:** left-sided paralysis and neglect, more impuslive, impaired judgement, tends to deny problems, short attention
512
What is a tonic clonic seizure? Describe tonic and clonic portions.
**Tonic-clonic seizure:** a seizure lasting 2-5 minutes where there is a tonic phase and clonic phase. **Tonic:** muscle stiffness and loss of consciousness **Clonic:** rhythmic jerking of all extremities
513
Hydantonins: what is it, meds, education
**1) What is it:** seizure medication that decreases sodium and calcium influx thereby stabilizing cell membranes **2) Meds:** Phenytoin, Fosphenytoin **3) Education:** Headache and drowsiness when starting, provide regular oral care and checks becuase it **can cause gingival hyperplasia**, **never give warfarin and phenytoin at the same time**, give IV for status epilecticus by diluting in .9% NS
514
Benzodiazepines: what is it, meds, education
**1) What is it:** GABA agonist allowing Cl- ions in to inhibit neurons **2) Meds:** Lorazepam, clorazepate **3) Education:** most often given IV for status epilepticus, clorazepate helps prevent seizures, **monitor for respiratory depression and hypotension**
515
What are seizure precuations (pre-seizure preparation)?
**1)** O2 and suction ready **2)** IV access on patient **3)** Side rails with pads up
516
What are priorities during seizures?
**1)** Protect from injury **2)** Do not place anything in their mouth **3)** Turn sideways to maintain airway **4)** Remove any injurious objects **5)** Suction oral secretions lightly **6)** Do not restrain, instead guide them **7)** Loosen restrictive clothing **8)** Record beginning and end times of seizure **9)** Remove pillow, raise side rails
517
What should you do after a seizure?
**1)** Take vitals **2)** Provide O2 if needed **3)** Check neurologic status **4)** Keep side lying **5)** Allow to rest **6)** Check mouth for blood d/t tongue/cheek bite
518
Status epilecticus: what is it, causes, priority, treatment
**1) What is it:** a medical emergency d/t prolonged seizure lasting longer than 5 minutes or repeated seizures over 30 minutes **2) Causes:** withdrawl from antiepileptic drugs, infection, acute alcohol withdrawal, TBI, cerebral edema, metabolic disturbances **3) Priority:** establish airway **4) Tx:** IV-push lorazepam/diazepam
519
Delirium: what is it, what are the subtypes, risk factors, management/tx, prevention
**1) what is it:** acute, abrupt, fluctuating course of disorientation, inattentiveness, disorganized thinking, altered level of consciousness, and cognition changes **2) Types:** Hyperactive = restless, agitated, aggressive; Hypoactive = quiet, stares, lethargic, unaware, moves slowly/not alot; mixed = both **3) Risk factors:** mechanical ventilation, sedation, old adults, alcohol disorders, organ disorders, low 02, UTI, insomnia **4) Management/tx:** O2 therapy if low, treating underlying cause (i.e. UTI), calm voice, reorient patient, ambulate them, provide comfort object **5) Prevention:** adequate lighting, clock and calendar in room, promote proper sleep-wake cycle, avoid unecessary meds and interventions, address pain, cluster cares at night
520
What is key to determining delirium?
Need to know their **baseline**
521
Alzheimer's disease: what is it, risk factors, diagnosis
**1) What is it:** specific and progressive cognitive loss affecting functional domains **2) Risk factors:** female, older adults, down syndrome, TBI, smoking, depression, CVD, excess stress, PTSD **3) Diagnosis:** mini-mental state exam (MMSE) = lower score, worse dementia, MoCHA, clock drawing test, PET (amyloid plaques), MRI to r/o, CT for structural changes
522
What are the symptoms of early, moderate, and severe stages of Alzheimer's?
**Early:** forgets names, misplaces items, less social, can do ADLs, unable to travel alone to new places **Moderate:** cannot handle finances well, disoriented to place and time, gets lost while driving, wandering **Severe:** agnosia, incapacitated, bedridden, cannot do ADLs, loss of mobility
523
What are safety interventions for those with Alzheimer's?
**1)** remove keys **2)** lock doors **3)** remove dangerous objects (knives, oven/stove, guns) **4)** lower bed **5)** use bed/chair alarm **6)** grab bars **7)** motion activated lights **8)** keep room quiet with TV off unless requested **9)** To prevent wandering place them close to nurses tation, have frequent checks or a sitter **10)** Keep away from stairs/elevators **11)** Consider if lines/drains are needed or camouflage them **12)** Toilet every 2 hours
524
When should you reorient versus redirect/validate for those with Alzheimer's disease?
Reorient in early stages Redirect/validate in late stages
525
Donepzil: what is it, what does it treat, what side effects should you monitor for?
**1) What is it:** a cholinesterase inhibitor prevening cholinesterase from breaking down acetylcholine allowing more to remain in the synapse improving ADLs **2) Treats:** Alzheimer's disease **3) Monitor:** Decreased heart rate, diziness, and falls d/t bradycardia
526
What is HIV?
**HIV:** a chronic and progressive immunodeficiency virus characterized by an attack on CD4 T cells leading to AIDS and death without treatment
527
What are risk factors/transmission methods of HIV? Select all that apply 1) Sharing needles 2) Kissing 3) Sharing a drink 4) Unprotected sex 5) Blood transfusions 6) Breast milk 7) Direct bodily fluid conact 8) Vaginal secretions 9) Sharing utensils
**1)** Sharing needles **4)** Unprotected sex (especially anally or with semenal contact) **5)** Blood transfusions **6)** Breast milk **7)** Direct contact with bodily fluids **8)** Vaginal secretions
528
What fluid presents the greatest risk in HIV transmission?
- Seminal fluid
529
Name each stage of HIV and its signs and symptoms:
**1) Acute infection:** generic viral flu-like symptoms including - Fever - Sore throat - Night sweats - Chills - Headache - Muscle ache **2) Latent or Chronic infection:** feels fine, **asymptomatic** **3) Acquired Immunodeficiency syndrome (AIDS):** Falling WBC count (< 200), individual expriences s/s of opportunistic infections that arise
530
What does the window period refer to in HIV testing? About how many days is it? | Also known as "seroconversion window"
**Window period:** It is the time frame in which there is a *high false negative rate* because seroconversion, or antibody production is not high enough to be detectable **Days:** 0-20 days
531
What labs might be elevated in a patient with HIV? (select all that apply) 1) Sodium 2) WBC 3) Potassium 4) Viral load
**2)** WBC (they are experiencing an infection) **4)** Viral load (they should have none without an infection, but they have HIV)
532
What 4 labs are primarily examined during an HIV infection?
**1)** Lymphocyte count (decreased) **2)** CD4+ count (decreased) **3)** Viral load testing (stage 2, increasing) **4)** WBC (increased)
533
What are some opportunistic infections that someone experiencing late stage HIV may experience?
**1)** Candida (thrush) **2)** Herpes (cold sores or genital) **3)** Kaposi's sarcoma **4)** Pneumonia **5)** Lymphoma **6)** Cytomegalovirus **7)** Toxoplasmosis **8)** Recurrent UTIs
534
What is required to make an AIDS diagnosis?
- Presence of HIV *AND* one or more of the two: **1)** < 200 CD4+ count **2)** Presence of opportunistic infections
535
What is ART stand for and what is it? Why is combination ART therapy used?
**ART:** Antiretroviral therapy which prevents HIV from replication decreasing viral load **Combination therapy:** It is used to both decrease viral load and increase immunity, you need one medication for each.
536
List one ART medication:
- Abacavir - Biktarvy - Emtricitabine
537
What are common side effects of ART medications:
**1)** Fatigue **2)** Weight loss **3)** Weight redistribution **4)** Diarrhea **5)** High cholesterol **6)** Mood changes **7)** Nasuea and vomiting **8)** Rash
538
As a nurse what recommendations would you provide to a patient with HIV experiencing lack of appetite/weight loss?
- Eat frequent, calorie dense, high protein, small means - Take supplements like vitamins A + E - Eat easy to swallow foods
539
As a nurse what recommendations would you provide to a patient with HIV experiencing weight redistribution?
- Exercise regularly - Consider the tesamorelin injection (reduces excess fat) - Metformin for those with diabetes
540
As a nurse what recommendations would you provide to a patient with HIV experiencing diarrhea?
- Reduce fatty, spicy, dairy, and high insoluble-fiber foods - OTC loperamide (antidiarrheal) - Increase fluid intake - Keep the perineal area dry
541
As a nurse what recommendations would you provide to a patient with HIV experiencing fatigue or sleep difficulties?
- Eat nutritious foods - Avoid smoking, caffeiene, alcohol, and napping - Stick to a sleep schedule - Relax before bed
542
As a nurse what recommendations would you provide to a patient with HIV experiencing high cholesterol?
- Regular exercise - Avoid smoking - Reduce fat intake - Increase omega-3 fatty acids
543
As a nurse what recommendations would you provide to a patient with HIV experiencing nausea and vomiting?
- Eat smaller, more frequent meals - Eat plain foods (crackers, rice) - Avoid fatty and spicy foods - Eat cold meals over hot - Consider antiemetic prescription
544
As a nurse what recommendations would you provide to a patient with HIV experiencing imapired skin integrity?
- ART therapy to prevent Kaposi's sarvoma - Keep weeping lesions dressed - Take analgesics - Keep skin dry - Take valcyclovir to reduce/prevent herpes lesions
545
How often should invididuals with HIV on ART be tested for drug efficacy?
- **Q4-6 weeks** for efficacy due to drug mutation or resistance (mainly when changing medications or starting new ones)
546
How often should a patient receive viral load testing to prevent opportunistic infections?
- Q4-6 months
547
548
What are 6 ways to prevent opportunistic infections in those with HIV?
**1)** Frequent handwashing **2)** Get tested for TB **3)** Receive yealy influenza vaccine **4)** Don't drink standing water **5)** Viral load testing Q4-6 months **6)** Take antivirals as ordered
549
What are risk factors for opportunistic infections in those with HIV?
**1)** Stopping ART therapy **2)** History of HIV **3)** Low CD4+ cell count
550
How often should vital signs and IV site checks take place for patients with HIV?
- Q4H
551
Are nurses allowed to refuse care to patient's with HIV that they have been assigned to?
No, they are not allowed to refuse care unless they have found an appropriate replacement for care and their refusal is based on religious beliefs
552
Which opportunistic infection is foscarnet sodium used to treat and what are two things you need to do when administering it?
**1)** Foscarnet sodium treats cytomegalovirus **2)** It should be placed on an infusion pump to administer because it needs to be infused slowly **3)** It is highly toxic to the kidneys thus serum creatinine levels need to be monitored
553
What is PrEP? How effective is it?
- It is preexposure prophylaxis to prevent HIV - 99% effective in reducing infection of HIV by sex
554
What is PEP? When must it be started by?
- Postexposure prophylaxis that is used after known or possible exposure to HIV - Must be **started within 72 hours (3 days)**
555
What is the initial lab testing for HIV? 1) Point-of-care testing 2) Western blot 3) HIV antigen/antibody combination assay 4) Chemiluminescent immunoassay
**4)** Chemiluminescent immunoassay is the initial lab test for HIV - Another test is done using Western Blot or point-of-care testing to confirm infection
556
What education should the nurse provide to patients with HIV to avoid infection?
**1)** Wash hands frequently **2)** Do not dig in the dirt, no houseplants **3)** Report any infections or low-grade fevers **4) Do not share any razors, toothbrushes, washcloths, toothpaste or deodarant** **5)** Replace toothbrushes after illness **6)** Do not eat undercooked or raw food **7)** Do not change pet litter boxes **8)** Avoid reptiles/turtles
557
A client diagnosed with acquired immunodeficiency syndrome (AIDS) is being admitted to the hospital for treatment of a Pneumocystis jiroveci respiratory infection. Which intervention would the nurse include when creating the plan of care to assist in maintaining the comfort of this client? 1. Monitoring for bloody sputum 2. Evaluating arterial blood gas results 3. Keeping the head of the bed elevated 4. Assessing respiratory rate, rhythm, depth, and breath sounds
**3)** Keep the head of the bed elevated
558
The nurse assesses the client diagnosed with acquired immunodeficiency syndrome (AIDS) for early signs of Kaposi’s sarcoma. What characteristics would be consistent with that lesion? Select all that apply. 1. Flat 2. Raised 3. Light blue in color 4. Resembling a blister 5. Brownish and scaly in appearance 6. Color varies from pink to dark violet or black
**1)** Flat **6)** Color varies from pink to dark violet or black
559
A client diagnosed with acquired immunodeficiency syndrome (AIDS) gets recurrent Candida infections of the mouth (thrush). The nurse has given the client instructions to minimize the occurrence of thrush and determines that the client understands the instructions if which statement is made by the client? 1. “I should use a mouthwash at least once a week.” 2. “I should use warm saline or water to rinse my mouth.” 3. “I should brush my teeth and rinse my mouth once a day.” 4. “Increasing the amount of red meat in my diet will keep this from recurring.”
**2)** “I should use warm saline or water to rinse my mouth.”
560
How does COVID-19 enter the body?
It binds to ACE-2 receptors found in vascular endothelium
561
Which organs can COVID-19 effect?
**1)** Lungs **2)** Liver **3)** Heart **4)** Brain **5)** Kidneys **6)** Intestines **7)** Pharynx
562
What systemic effects can COVID-19 have?
**1)** Vasoconstriction **2)** Inflammation **3)** Hypercoagulability **4)** Endothelial dysfunction **5)** Edema
563
What are primary prevention methods for COVID-19?
**1)** Immunization **2)** Physical distancing **3)** Handwashing **4)** Face masks
564
When are you fully vaccinated against COVID-19?
2 weeks following the final dose of the primary series
565
How long does a COVID-19 vaccine provide immunity?
- 6 months+
566
How long after administering the COVID-19 vaccine should you monitor patients for?
Monitor patients for 15 minutes after administration
567
What are risk factors for COVID-19?
**1)** 65+ years old **2)** Comorbidities (cancer, chronic kidney/liver/lung disease) **3)** Diabetes **4)** Heart conditions **5)** HIV **6)** Smoking
568
****What are the core signs and symptoms of COVID-19?
**1)** Cough **2)** Fever **3)** Chills **4)** SoB **5)** Muscle/body aches **6)** Loss of taste/smell **7)** Sore throat **8)** Nausea/vomiting
569
****What are signs and symptoms that a patient's COVID-19 is progressing, indicate an emergency, or require immediate treatment?
**1)** Trobule breathing **2)** Persistent chest pain/pressure **3)** New confusion **4)** Inability to stay awake **5)** Blue lips **6)** Tachypnea **7)** Hypoxemia **8)** Orthopnea (difficulty breathing while lying down) **9)** Edema **10)** Hemoptysis **11)** Increasing dyspnea or dyspnea at rest
570
****What are the prioties in COVID-19?
**1)** Preventing the spread to others **2)** Impaired oxygenation **3)** Preventing severity of symptoms
571
What PPE should be used when treating patients with COVID-19?
**1)** N95 **2)** Eye protection **3)** Isolation Gown **4)** Nonsterile gloves
572
What eduction should the nurse provide to patients with COVID-19 to prevent the spread of infection?
**1)** Stay at home **2)** Wear a mask **3)** Use a separate bathroom **4)** Limit caregivers **5)** Do not share utensils, beddings, or dishes **6)** Clean used spaces
573
What are ways to promote oxygenation in a patient with COVID-19?
**1)** Reposition and ambulate (as tolerated) frequently **2)** Change to a stomach-lying (self-proning) position **3)** Cough and deep breath Q2H **4)** Increase fluid intake
574
What is the primary method of diagnosing an active COVID-19 infection? 1) Nucleic acid amplification test (NAAT) 2) Point-of-care antigen test 3) Antibody tests (serology) 4) Immunoassay replication
**1)** Nucleic acid amplification test (NAAT)
575
What imaging can be done in COVID-19?
- Chest x-ray for lung infiltrates
576
What is the preferred drug to treat COVID-19? What is its indication, side effects, and education to provide to patients?
**Preferred drug:** Nirmatrelvir-Ritonavir **Indication:** mild to moderate COVID-19 at risk of pregression to severe infection **Side effects:** diarrhea + altered taste **Education:** take missed doses within 8 hours of time, if over 8 skip the dose
577
True or false: Remdesivir is the preferred drug in treating COVID-19
**False:** remdesivir is not the preferred drug, instead it is nirmatrelvir-ritonavir
578
Remdesivir: indication, side effects, monitoring
**Indication:** hospitalized patients with COVID-19 or within 7 days for unhospitalized patients **Side effects:** hepatotoxicity + nausea **Monitoring:** - Hepatic panel - PT before each administration - Montior for hypersensitivity during and following administration
579
What types of pneumonia can there be?
**1)** Viral **2)** Bacterial **3)** Fungal
580
What is pneumonia?
An infcetion in the lungs that causes inflammation and thick fluid/exudate build up in the alveoli
581
What are risk factors for community acquired pneumonia?
**1)** Older adult **2)** No pneumococcal, COVID-19, or influenza vaccination **3) Reduced immunity** **4)** Tobacco/alcohol use
582
What are risk factors for hospital or ventilator acquired pneumonia?
**1)** Older adult **2)** Chronic lung disease **3)** Altered LoC **4)** Recent aspiration **5)** Endotracheal/NG tube **6) Reduced immunity** - Steroid use, cancer pt., transplant, immunosuppresants **7)** Mechanical ventilation **8)** Reduced mobility **9)** Poor nutrition **10)** Drugs that increase gastric pH
583
What is more common, community acquired pneumonia or hospital/ventilar acquired?
Community acquired is more common
584
What are systemic signs and symptoms of pneumonia?
**1)** Fever **2)** Chills **3)** Malaise **4)** Loss of appetite **5)** Myalgias
585
What are pulmonary signs and symptoms of pneumonia?
**1)** Tachypnea **2)** Dyspnea **3)** Cough w/ or w/o sputum (bloody possible) **4)** Labored breathing **5)** Diminished lung sounds **6)** Crackles, rhonchi, wheeze **7)** Low O2 **8)** Diminished chest expansion **9)** Pleuritic chest pain on inspriation
586
What labs can you check for pneumonia?
**1)** WBC (elevated) **2)** Sputum **3)** Blood culture (sepsis) **4)** ABGs **5)** Electrolytes (hyponatremia) **6)** BUN/creatinine **7)** Check for lactate (sepsis)
587
What imaging can be done in pneumonia?
Chest x-ray, especially for older adults
588
How can pneumonia be prevented?
**1)** Vaccination (influenza, pneumococcal, COVID-19) **2)** Handwashing **3)** Avoid crowds and sick people **4)** Aspiration precautions **5)** 3L of fluids/day **6)** Avoid pollutants **7)** Enough sleep/rest
589
How to prevent hospital acquired pneumonia?
**1)** Pulmonary hygiene (incentive spirometry, CDB, ambulate) **2)** Hydration **3)** Oral care (2x/day)
590
How to prevent ventilator associated pneumonia?
**1)** HOB >30 **2)** Oral care **3)** Hand hygiene **4)** Sterile suctioning **5)** DVT prophyaxis **6)** Daily weaning assessment **7)** Stress ulcer prophylaxis
591
How can you as a nurse promote gas exchange in those with pneumonia?
**1)** HOB high fowlers **2)** Early ambulation **3)** 2-3L/day **4)** Keep O2 above 90% **5)** Incentive spirometry **6)** CDB Q2H **7)** Bronchidilators
592
How can you as a nurse prevent possible airway obstructions in patients with pneumonia?
**1)** Bronchodilators **2)** CDB **3)** Incentive spirometry **4)** 2-3L/day **5)** IV steroids **6)** Expectorants
593
How can you monitor for sepsis in pneumonia?
**1)** Obtain blood cultures **2)** Administer antiinfectives as prescribed **3)** Check vitals **4)** Maintain BP
594
What two medications can be used to support airways in pneumonia? What action do they do and what is the monitoring or side effects of both?
**1)** Albuterol - **Action:** bronchodilate - **Side effects:** Tachycardia, tremors **2)** Steroids - methylprednisolone - **Action:** anti-inflammatory, prevents swelling - **Montior:** blood glucose - **Education:** do not stop abruptly
595
Ceftriaxone: class, action, teaching, SE
**Class:** cephalosporin antibiotic **Action:** broad spectrum **Teaching:** complete entire course **Side effects:** very safe -> allergic reaction + cross sensitivity with penicillins
596
Levofloxacin: class, action, teaching, SE
**Class:** antibiotic, fluoroquinolone **Action:** broad spectrum **Teaching:** take with food, avoid sun exposure, complete entire course **Side effects:** tendon swelling/rupture, c. diff/yeast infection, nausea, vomiting
597
How long within arriving at the ED should antibiotics be given for treating pneumonia? 1) Within 4 hours 2) Within 6 hours 3) Within 1 hour 4) Within 2 hours
**1)** Within 4 hours
598
What are the Systemic Inflammatory Response Syndrome (SIRS) criteria and how many do you need to be diagnosed?
*At least two* of the following to diagnose: **1)** Temperature of above 100.4F (38C) or below 96.8F (36C) **2)** Heart rate above 90 **3)** Respiratory rate above 20 or PaCO2 below 32 **4)** WBC above 12,000 or below 4,000
599
What are the requirements for a diagnosis of sepsis?
**1)** SIRS criteria have been met **2)** Confirmed or suspected infection
600
What two criteria indicate severe sepsis?
**1)** Vasopressors to keep MAP above 65mmHg **AND** **2)** Serum lactate above 2mmol/L despite fluid resuscitation
601
What indicates septic shock, also known as multiple organ dysfunction syndrome?
Must have SIRS and sepsis AND meet MODS criteria: organ failure and poor clotting with uncontrolled bleeding in two or more organ system
602
What are signs/symptoms of warm and cold shock?
**Warm:** (things are relatively normal) - Decrease in capillary refill - Decreased systemic vascular resistance - Normal to increased cardiac output - warm extremities **Cold:** - Decompensation leading to increased systemic vascular resistance to shunt blood to vital organs - Decreased cardiac output - Cold extremities - Delayed capillary refill
603
True or false: septic shock is nearly irreversible once a patient is in this state
**True**: septic shock, also known as cold shock, is nearly irreversible once a patient is in this state due to multiple organ failure and rapid decline
604
What are risk factors for sepsis?
**1) Patients with reduced immunity (chronic diseases) 2) Patients with lines (especially central lines), tubes, and drains** **3)** Large open wounds **4)** Invasive procedures **5)** Malnutrition **6)** 80+ y/o **7)** Diabetes **8)** CKD **9)** Hepatitis **10)** Blood soaked gauze staying in contact for a long period of time
605
What are ways to prevent sepsis?
**1)** Remove any lines, tubes, and drains **2)** Sterile technique for insertions **3)** Maintain mucus membranes and skin **4)** Sepsis screening and assessment to notice changes from baseline (use validated tools like MEWS, qSOFA) **5)** Wean from ventilator ASAP **6)** Take temperature 2x/day **7)** Educate family on s/s of infection
606
What are the cardiovascular signs and symptoms of sepsis?
**Early:** normal to increased HR and BP, increased CO **Late:** low blood pressure and even more low during septic shock - cytokines keep blood vessels dilated, decreased CO, slow capillary refill **Disseminated intravascular coagulation (DIC):** widespread hypoxia and ischemia leads to poor clotting as clotting factors are used up for unnecessary clotting - Low platelets, high INR and aPTT
607
What are the respiratory signs and symptoms of sepsis?
**1)** Increased respiratory rate (tachypnea) **2)** Low O2 saturation (hypoxia) **3)** ARDs
608
What are the neurological signs and symptoms of sepsis?
**1)** Restless **2)** Feels like something is wrong **3)** Confusion
609
What are the skin (integumentary) signs and symptoms of sepsis?
**Early:** warm and no cyanosis **Late (septic shock):** cool, clammy, pale skin, mottling, cyanotic, petechia and ecchymosis can occur d/t DIC
610
What are the urinary signs and symptoms of sepsis?
**1)** Low urine output (worsening with shock) - If they have no reason to have oliguria, suspect shock **2)** Increased creatinine
611
What are the liver signs and symptoms of sepsis?
**1)** Hyperglycemia, high blood glucose
612
What labs would be examined in sepsis?
**1)** Procalcitonin (high) **2)** Lactate (>2mmol/L, high) **3)** WBC (>12 or < 4, high or low with decreasing neutrophils) **4)** Bacteria in the blood **5)** Cultures **6)** Blood glucose (high) **7)** Late = Low hematocrit, hemoglobin, fibrinogen, and platelets d/t DIC
613
What are the priorities in sepsis?
**1)** Early identification **2)** Widepsread infection **3)** Potential for MODs
614
What is the 1-hour protocol for sepsis? | 5 things
**1)** Lactate levels **2)** Draw labs/cultures x2 before antibiotics so long as it doesn't delay antibiotics by 45min **3)** Administer broad spectrum antibiotics **4)** Rapid administration of 30mL/kg crystalloid fluids for hypotension or lactate >4mmol/L (especially within first 3 hours) **5)** Apply vasopressors if hypotensive during or after fluid resuscitation to maintain MAP >65 mmHg
615
What interventions are completed during sepsis? | 7 things (2 extra)
**1)** Screening for early detection **2)** O2 therapy, possible mechanical vent **3)** Antibiotics within 1 hour (cultures before antibiotics) **4)** Insulin to manage blood glucose **(keep between 140-180)** **5)** Corticosteroids to manage adrenal insufficiencies **6)** Heparin therapy for clotting **7)** Blood replacement for poor clotting **(platelets first choice)** **8)** Bicarb if pH below 7.2 with AKI **9)** DVT prophylaxis within 72 hours
616
True or false: Source control to find the infection must be done between 6-12 hours
**True:** source control to find the infection must be done between 6-12 hours to eliminate the infection
617
What is the desired urine output for those who are recovering or recovered from sepsis? 1) >65mmHg 2) >/= 0.1 mL/Kg/Hr 3) >/= 0.5 mL/Kg/Hr 4) < 65mmHg
**3)** >/= 0.5mL/Kg/Hr
618
What is the bundle for preventing Ventilator-associated Infections (VAP)? | 8 things (2 extra)
**1) HOB 30 degrees** **2)** Oral care Q12H w/ antimicrobial rinse (mouth ulcer prophylaxis) **3)** Prevent aspiration **4)** Subglottic suctioning **5)** Pulmonary hygiene (turning, positioning, chest physiotherapy) **6)** Daily assessment for extubation (minimize sedation) **7)** Maintain cuff pressure (15-20mmHg) **8) Hand hygiene when caring for ET tube** **9)** Early ambulation **10)** DVT prophylaxis
619
You should always assess that patient first when something is going wrong during mechanical ventilation (breathing, color, O2 sat). What does the DOPE acronym mean?
**D:** dislodgement **O:** obstruction **P:** pneumothorax **E:** equipment
620
List some things the nurse should do or know when caring for mechanically ventilated patients:
**1)** Maintain patent airway (assess Q2-4hrs) **2)** Turn Q2H and assess lung sounds after **3)** Assess vitals Q4H **4)** Empty tubing with mositure collection - do not let it go into the humidifier **5)** Include family when possible **6)** Moisten oral mucosa Q2-4H **7)** Move ET tube to opposite side of the mouth Q24H **8)** Teach patients to avoid valsava maneuvers d/t hypotension (monitor I/Os, weight, urine output) **9)** Keep TV low w/ moderate PEEP **10)** Avoid excessive carbs in patients with COPD b/c it increases CO2 production
621
What should blood sugar be kept between during insulin treatment during sepsis? 1) 70-120 2) < 60 3) 120-140 4) 140-180
**4)** 140-180
622
If needing to replace blood after DIC d/t sepsis, what is the first choice?
Platelets are the first choice
623
What are the priorities in cirrhosis?
**1)** Fluid overload - third spacing for ascietes **2)** Possible hemorrhage d/t GI varices and portal hypertension **3)** Acute confusion d/t elevated ammonia and hepatic encephalopathy **4)** Pruritis
624
What is liver cirrhosis?
- Extensive and irreversible scarring of the liver from inflammation and fibrosis - Scarring and inflammation creates pressure on the liver further damaging the cells and vessels - Nodules form blocking bile ducts and impair blood flow - Liver shrinks and becomes hard
625
What are causes of liver cirrhosis?
**1)** Viral hepatitis (hep C) **2)** Chronic alcoholism **3)** Chronic biliary obstruction
626
What are complications of liver cirrhosis? | 8 complications
**1) Portal hypertension:** increased pressure in the portal vein backflowing to the spleen -> splenomegaly, platelet destruction, and **thrombocytopenia (often first sign)** - Backflows into esophageal veins - Flows into abdomen too **2) Ascietes:** fluid shift into the peritoneum from portal hypertension and hypoalbuminemia and esophageal varices (bleed risk) - Fluid into peritoneum also causes decreased albumin circulation - Massive ascietes can cause RAAS to activate causing more retention **3) Biliary obstruction:** cannot absorb vitamin K = bleeding risk and jaundice **4) Hepatic encephalopathy:** change in mental status, reverisble if caught early, d/t blood shunting from portal vein to central cirulation allowing unprocessed substances (ammonia) **5) Gastropathy:** slow gastric mucosal bleeding, chronic blood loss anemia **6) Hepatorenal syndrome:** sudden decrease in urine output, increased BUN + creatinine, increased urine osmolarity **7) Peritonitis:** bacteria from bowel reach the ascitic fluid causing infection **8) Hepatopulmonary syndrome:** excesscive asitic volume causing dyspnea d/t increased intraabdominal pressure limiting thoracic expansion + diaphragm function
627
What are signs and symptoms of esophageal varices rupture/bleed?
**1)** Bright red emesis **2)** Melena (black tarry stool) **3)** Decreased level of consciosness **4)** Hypovolemia (**Tachycardia,** hypotension, high RR, low Hgb, low Hct, weak pulses, oliguria, cold)
628
What are early signs and symptoms of cirrhosis?
**Early (vague and nonspecific)** **1)** Fatigue **2)** Weight changes **3)** Anorexia **4)** Vomiting **5)** Abdominal and liver pain **6)** Thrombocytopenia
629
What are late signs and symptoms of cirrhosis?
**1)** GI bleed **2)** Jaundice **3)** Ascites **4)** Spontaneous bleeding **5)** Dry, itchy skin **6)** Icterus (jaundice of the eyes) **7)** Rashes **8)** Peripheral edema **9)** Weight gain **10)** Palmar erythema **11)** Purpuric lesions/petechiae **12) Asterixis:** hand flapping
630
What labs are examined during cirrohsis?
**1) ALT (increased)** **2)** AST (increased) **3)** Bilirubin (increased) **4)** Albumin (decreased) **5)** Prolonged PT/INR **6)** Ammonia (increased) **7)** Thrombocytopenia (low platelets) **8)** Anemia (low Hgb, low Hct, low RBC) **9)** Hypokalemia (bleeding risk)
631
What diagnostic imaging is used for liver cirrhosis?
**1)** Abdominal x-ray **2)** CT/MRI **3)** Ultrasound (ascietes, hepato/splenomegaly)
632
How can you help treat fluid overload in liver cirrohsis?
**1)** Low salt diet **(1-2g)** **2)** Late stage IV vitamins like thiamine, folate, and a multivitamin **3)** Diuretics (daily weights, I/Os) **4)** Paracentsis if respiratory is impacted (have them void before the procedure, vitals and weight before and after) **5)** Auscultate lungs Q4-8H **6)** Transjugular intrahepatic portal system shunt (shunt to remove ascietes long term and controls bleeding)
633
What class of medication and medication can help prevent bleeding in liver cirrhosis? Why is it used? What should you monitor, what are the side effects, and what do you educate patients on?
**- Propranolol (beta-blocker):** helps prevent bleeding by reducing heart rate and hepatic venous pressure gradient **- Monitor:** blood pressure and heart rate (hypotension and bradycardia) - hold if SBP < 100 or HR is < 60 **- Side effects:** weakness, fatigue, bronchospasm **- Education:** rise slowly as it may cause orthostatic hypotension
634
What are ways to treat hemorrhage in liver cirrhosis?
**1)** Propranolol (beta-blocker) **2)** Vasoactive medications like *Octreotide acetate* (suppress gastrin, serotonin, and intestinal peptide decreasing GI blood flow) **3)** Endoscopy to find and stop the source - endoscopic variceal ligation (banding) to decrease flow **4)** Pure RBCs, FFP, platelets **5)** Emergency balloon tamponade **6)** Antibiotics to prevent infection which can cause bleeding
635
What medication is used to treat confusion in liver cirrhosis? What does it do, what is the goal for this medication, what are the side effects
**- Lactulose:** reduces pH and increases osmotic pressure to draw in water to the intestines, and converts NH3 to NH4, which can be excreted, all of which help *reduce ammonia levels via stool* **- Goal:** 3 bowel movements per day **- Side effects:** bloating and cramping
636
What are ways to treat or prevent confusion in liver cirrhosis?
**1)** Minimize hepatoxic medications and medications that are difficult for the liver to metabolize -> Opioids, sedatives, barbituates **2)** Administer lactulose to excrete ammonia **3)** Administer nonabsorbable antibiotics to destroy flora decreasing ammonia production -> Neomycin **4)** Moderate protein low fat diet for high ammonia
637
How can you treat pruritis in liver cirrhosis?
**1)** Moisturizers **2)** Cool compress **3)** Corticosteroid creams **4)** SSRIs
638
What hepatotoxic medications should be avoided in liver cirrhosis?
**1)** Acetaminophen **2)** NSAIDs **3)** Alcohol
639
What is pancreatitis?
Autodigestion of the pancreas by enzymes that activate prematurely before reaching the intestines
640
What causes pancreatitis?
Inflammation of the pancreatic duct and obstruction increasing pressure and duct rupture leaading to enzyme release within the pancreas
641
What are risk factors of pancreatitis?
**1) Alcohol consumption (primary risk factor)** **2)** Biliary tract disease (gallstones can obstruct) **3)** Hyperlipidemia, hyperparathyroidism, hypercalcemia **4)** Trauma **5)** GI surgery **6)** Kidney failure
642
What are two ways to prevent pancreatitis?
**1)** Avoid excessive alcohol consumption **2)** Have a low-fat diet
643
What are signs and symptoms of pancreatitis?
**1)** Sudden, severe, knife-like or boring pain **2)** Pain is in LUQ or epigastric **3) Pain is worse when lying down** **4)** Pain relieved by fetal position or upright **5)** Nausea and vomiting **6)** Weight loss **7)** Ecchymosis on flanks and blue-gray periumbilical color **8)** Jaundice **9)** Hypoactive bowel sounds **10)** Ascietes **11)** Warm, moist, fruity breath (hyperglycemia)
644
What labs would you expect to draw/or to be requested in pacreatitis?
**1) Amylase (increased)** **2)** WBC (increased) **3)** Platelets (decreased) **4)** ALT/AST (increased) **5)** Ca2+ and Mg2+ (decreased) **6)** Bilrubin (increased) **7)** Blood glucose (increased) **8)** ESR (increased)
645
What are nonpharmacological ways to treat pancreatitis?
**1) NPO until pain free (rest the pancreas)** **2)** Resume diet with bland, high protein, low fat, non-stimulant foods (no coffee) **3)** Small, frequent meals **4)** Side-lying, upright, fetal position, or leaning forward (lying down is more painful) **5)** No alcohol or smoking **6)** Antiemetics PRN (nasogastric decompression if bad) **7)** Limit stress **8)** Enteral or parenteral nutrition if severe
646
What medication can be used to treat acute pain and mild-moderate pain during pancreatitis? What medication should be avoided?
**1) Acute pain:** morphine or hydromorphone **2) Mild-moderate pain:** Ketorlac (NSAID) **3) Avoid:** meperidine b/c of seizure risk
647
What two medications can be used to reduce gastric acid secretion in pancreatitis? What do they do and what should you monitor or do?
**1) Cimetidine:** histamine receptor antagonist to decrease gastric acid secretion - Give 1 hour before or after antacid **2) Omeprazole:** proton pump inhibitor to decrease gastric acid secretion - Monitor for hypomagnesemia
648
What medictation must be used to with meals and snacks for those with pancreatitis? What does it do, moitoring/side effects, education?
**Pancrealipase (Creon):** aids with fat and protein digestion **- Side effects:** monitor for headaches, cough, dizziness, and sore throat **- Education:** - Take with meals and snacks - Capsule can be opened and sprinkled on non-protein food - *Drink with a full glass of water after taking* - Wipe lips and rinse mouth - Take after histamine/antacid
649
Aside from pain, what is the main complication that pancreatitis can cause and why? How do you treat it?
**Complication:** Hypovolemia d/t extreme fluid shifting from retroperitoneal loss of protein-rich fluids **Tx:** IV fluids and electrolytes
650
What is a mechanical bowel obstruction?
When the bowel is physically blockes by problems outside the intestines, in the bowel walls, or in the intestinal lumen
651
What is a nonmechanical bowel obstruction?
Known as paralytic ileus or just ileus, a nonmechanical obstruction does not involve a physicl obstruction, instead peristalsis is decreased or absent d/t neuromuscular disturbance causing slowed movement or backup of intestinal contents
652
Why does abdominal distension occur in mechanical and nonmechanical obstructions?
It occurs becuase intestinal contents back up at or above the obstruction. The GI system tries to compensate by increasing peristalsis and increasing secretions, which worsens the block causing edema and capillary leakage into the abdomen d/t the high presure.
653
Where do obstructions occur in the GI system to cause alkalosis and acidosis?
**Alkalosis:** high in the small intestine (vomiting stomach acid and NG suction) **Acidosis:** End of small intestine or in the large intestines (loss of bicarbonate)
654
Where are obstructions most likely to occur? 1) Duodenum 2) Jejunum 3) Ileum 4) Sigmoid colon
**3)** **ileum** of the small intestine because it is the **smallest, most narrow** location
655
What are causes of mechanical bowel obstruction?
**1) Adhesions** (scar tissue from surgery or pathology) **2)** Benign or malignant **tumors** **3)** Appendicitis complications **4) Fecal impaction** (older adults) **5)** Strictures d/t Chron's inflammation and radiation therapy **6) Intussusception:** one piece of bowel folds or telescopes into another segment overlapping **7) Volvulus:** twisting of the intestine **8)** Fibrosis d/t endometriosis
656
What are causes of nonmechanical bowel obstructions?
**1) Handling of intestines during surgery** **2)** Peritonitis d/t leakage of colon contents irritating and inflamming the GI **3)** Intestinal ischemia d/t arterial or venous thrombosis or embolus decreasing blood flow to or in mesenteric vessels **4)** Hypokalemia can predispose patients to ileus
657
What are risk factors for bowel obstructions?
**1)** Bowel surgery **2)** Intestinal tumors/cancer **3)** Older adults **4)** Constipation **5)** Family history of colorectal cancer
658
How can you prevent bowel obstructions?
**1)** 2-3L fluid/day **2)** Regular exercise **3)** High fiber diet **4)** Stool softener PRN (docusate) **5)** Bulk forming medication (miralax) **6)** Early detection/screening for colorectal cancer
659
If an obstruction is suspected, what should be the first course of action the nurse should take?
Keep patient NPO and call a provider
660
What are signs and symptoms of a small intestine mechanical obstruction?
**1)** Midabdominal pain/cramping (Straingulation pain is persistent and localized) **2)** Vomiting, profuse if proximal SI obstruction **3)** Vomitus with bile and mucus, orange-brown, foul d/t bacteria **4) Obstipation:** no passage of stool **5)** No flatus **6)** Diarrhea in partial obstruction **7)** Metabolic alkalosis **8)** Upper abdominal distension
661
What are signs and symptoms of a large intestine mechanical obstruction?
**1)** Mild, intermittent, colicky pain **2)** Lower abdominal distension **3) Obstipation:** no passage of stool **4)** Ribbon-like stool if partial **5)** Blood in stool **6) Borborygmi:** high-pitched bowel sounds associated with cramping in early obstruction **7)** Absent bowel sounds during late stages **8)** Metabolic acidosis
662
What are signs and symptoms of ileus or nonmechanical bowel obstruction?
**1) Constant, diffuse pain** **2)** Abdominal distension **3)** Pain d/t ischemia is severe and constant **4)** Early decreased bowel sounds and absent later **5)** Vomiting gastric contents and bile is frequent, **rarely has foul odor like SI mechanical obstruction** **6)** Obstipation may be present
663
What signs and symptoms might indicate a perforated bowel?
**1)** Severe pain that goes away **2)** Fever **3)** Tachycardia **4)** Hypotension **5)** Abominal rigidity Report immediately
664
What labs are examined during a suspected bowel obstruction?
**No definitive labs** but: **1)** High hemoglobin, hematocrit, and BUN d/t dehydration **2) Hyponatremia, Hypokalemia, Hypochloremia** **3)** Increased amylase
665
What is the typical imaging for bowel obstructions?
**1) Abdominal CT** **2)** Abomdinal x-ray **3)** Ultrasound (find probable cause) **4)** Endoscopy (definitive cause)
666
How should bowel obstructions be nonsurgically managed if no strangulation or ischemia?
**1)** Keep NPO **2)** Insert nasogastric tube for decompression -> low continuous suction - Monitor proper output and placement Q4H **3)** IV fluids and electrolyte replacements (mainly sodium and potassium) for all obstructions **4)** Frequent oral care **5)** Pain control -> place in semi-fowlers and use analgesics with caution
667
What is the gold standard to confirm nasogastric tube (NGT) placement? 1) CT 2) X-ray 3) Ultrasound 4) MRI
**2)** X-ray is the gold standard - It's also important try and aspirate some gastric contents to verify location
668
What is the management for complete obstructions? What kind of procedures?
**1)** Complete obstructions: surgical management **2)** Exploratory open laparotomy or laproscopic surgery (closed) - Colostomy or even colon resection - NGT tube inserted until GI motility returns and can withstand some intake
669
What type of ostomy is more irritating to the skin and why?
An **ileostomy is more irritating to the skin** than a colostomy becuase stool is more watery and less formed d/t it's placement in the small intestine
670
Describe an ileostomy: placement, output, stool characteristics, diet to follow, etc.
**1)** At ileum (bypasses entire large intestine) **2)** Located in RLQ **3)** Initial output can be up to 2L/day **4)** Stool: green, odorless, loose **5)** Diet: low-residue **6)** Watch for enteric coated medications
671
Describe a colostomy: Placement, stool characteristics, diet to follow
**1)** In the large intestine either right or left **2)** RLQ or LLQ **3) Stool:** more formed if lower (LLQ), higher is more liquid (RLQ) **4) Diet:** Regular
672
What should a healthy stoma look like?
**1)** red/pink **2)** Moist **3)** Protrudes 1-3cm
673
What should an immediate postoperative stoma look like?
- Edematous - Small bleeding is expected - Stool should come in 2-5 days
674
What does an unhealthy stoma look like?
**1)** Dark red, purple, black **2)** Dry **3)** Ischemic **4)** Heavy bleeding = immediately report to surgeon
675
What should an unhealthy peristomal area look like?
**1)** Redenned **2)** Moist **3)** itchy **4)** Impaired skin integrity
676
How can nurses prevent peristomal breakdown?
**1)** Cleanse the peristomal area with mild soap and water (no alcohol) **2)** Dry the area before applying a new bag **3)** Enure a good, secure fit for the bag **4)** The ostomy bag barrier should be cut 1/8 inch
677
What locations might cause fluid and electrolyte imbalances for ostomies?
- Any locations that are higher up in the GI system (ileostomies and higher colostomies)
678
What foods should individuals with new ostomies avoid to prevent blockages?
**1)** Stringy vegetables **2)** Popcorn **3)** Fresh tomatoes
679
What foods should individuals with ostomies avoid that are gas producing?
**1)** Broccoli, **2)** Cabbage, **3)** Corn, **4)** Fish
680
How is a recurrent urinary tract infecetion defined?
2+ infections within 6 months or 3+ in a year
681
What does uncomplicated versus complicated UTI mean?
**Uncomplicated:** no anatomical or functional abnormality of the urinary tract that makes the risk for infection or treatment failure higher **Complicated:** the presence of an anatomical or functional abormality that increases infection risk or treatment failure (i.e. pregnancy, male sex, obstruction, diabetes, CKD, etc.)
682
What is colonization?
Bacterial presence in the urine or urinary tract but with **NO symptoms**
683
List possible risk factors/contributors to cystitis (UTI):
**1) Reduced immunity** **2) Female sex** - Short urethra - Urethral opening closer to anus **- Hormonal changes such as menopause and low estrogen** - Pregnancy **3)** Male sex - Prostate enlargement creating stasis - Loss of prostate proteins with age **4)** Stones (calculi = obstruction, surface irritation) **5)** Diabetes (glucose for bacterial and neuropathy = flaccid bladder) **6)** Concentrated urine **7)** Recent antibiotic use **8) Sexual intercourse** **9) Indwelling foley**
684
What risk factor is the strongest factor contributing to cystitis (UTIs)?
Sexual intercourse
685
What are signs and symptoms of acute complicated cystitis? | Think of having the flu along with specific tenderness and pain to a UTI
**1)** Fever **2)** Flank pain **3)** Chills/rigors **4)** Malaise **5)** Costovertebral angle tenderness **6)** Pelvic pain in women or perineal pain in men
686
What pathogen is responsible for most cystitis (UTIs)? What are other possible pathogens?
**1)** E. coli (80% of infections) **2)** Candida **3)** Enterococcus (less common) **4)** Klebsiella (less common)
687
What are examples of noninfectious cystitis causes?
**1)** Chemical exposure **2)** Radiation therapy **3)** Immunity issues like SLE (lupus)
688
What is interstitial cystitis and what are its signs and symptoms?
**Interstitial cystitis:** chronic inflammation of the *entire* urinary tract (bladder, urethra, muscles) that is related to genetic and immunity dysfunction, **NOT infection** **S/S:** **1)** Pain with bladder filling and/or voiding **2)** Increased urinary frequency **3)** Increased urinary urgency **4)** Nocturia **5)** Suprapubic and/or pelvic pain
689
What are the key signs and symptoms of cystitis or urinary tract infections?
**1) Inreased urinary frequency** **2) Increased urinary urgency** **3) Dysuria (Burning while voiding)** **4)** Suprapubic pain **5)** Nocturia **6)** Urinary incontinence **7)** Urinary retention **8)** Hematuria **9)** Pyuria (WBC in urine) **10)** Bacteriuria **11)** Feeling of incomplete bladder emptying
690
What signs and symptoms might an older adult present with if they have cystitis (UTI)?
**1) Change in mental status - confusion** **2)** Dysuria **3)** Urinary incontinence **4)** Nocturia **5)** Urgency **6)** Decreased well-being
691
How might vitals be changed in cystitis or UTI?
**1)** Increased HR **2)** Low BP **3)** Increased RR
692
What labs are examined during cystitis (UTI)?
**1)** Urinalysis - Positive leukocyte esterase and nitrate is sensitive - Presence of WBCs (pyuria), RBCs, and casts **2)** Culture (determine bacteria) **3)** Cystoscopy (for recurrent UTIs and interstitial cystitis) **4)** CT
693
How do you prevent catheter-associated urinary tract infections (CAUTI)?
**1)** Use sterile technique when inserting catheters **2)** Hand hygiene **3)** Only use if necessary - Perioperative PRN - Acute retention/obstruction - Measurement of urine during critical illness or injury - Palliative - Wound healing d/t incontinence **4)** Routine hygiene to clean periurethral area not antiseptic **5)** Assess need for catheter daily
694
How can you prevent cystitis (UTIs)?
**1)** Drink 2-3L fluids/daily **2)** Good hand hygiene **3)** Good sleep, rest, and nutrition for immune health **4)** Avoid spermicides **5)** Do not delay urination (Don't hold it) **6)** Women should clean perineum and empty bladder before and after sexual intercourse **7)** Wipe from front to back only **8)** Men should clean perineum before intercourse
695
What is the drug of choice for Candida based cystitis (UTI)?
**Fluconazole** is the drug of choice for Candida infections because it is an antifungal
696
Phenazopyridine: what drug class is it, what does it do, side effects, education
**Class:** antispasmodic/urinary analgesic **Action:** decreased bladder spasms, promotes bladder emptying, and provides pain relief (it does **NOT** treat the infection) **Side effects:** turns tears and urine orange to red that may stain clothing **Education:** Take with food
697
What antibiotic education should you give for those with cystitis (UTIs)?
**1)** Complete full course **2)** Avoid sun exposure d/t sensitivity **3)** Report any diarrhea or allergic reaction symptoms
698
What non-pharmacological methods can be used to treat cystits (UTIs)?
**1)** Warm sitz bath 3x/day for 20 minutes **2)** Increase fluid intake to atleast 1.5L **3)** Drink cranberry juice is it can reduce bacteral ability to adhere to cells - avoid in intersitial cystitis **4)** Avoid spices, soy products, and tomato products to reduce irritation and pain
699
What is hemodialysis and when is it indicated?
**Hemodialysis:** is the processes of a machine filtering the blood to remove excess fluid, eletrolytes, and waste **Indication:** when medications, diet, and fluid restrictions are no longer effective leading to uremic symptoms and fluid and electrolyte imbalances
700
What is used for accessing the body for short-term and long-term dialysis? How long does long-term access take to mature?
**1) Short-term:** HD catheter **2) Long-term:** Arterial-venous fistula - Takes up to 4 months to mature, 50% do not make it to maturity
701
Why are some medications given after hemodialysis?
They may dialyze off if given before and the patient loses out on whatever benefit it was supposed to give.
702
What education should you provide to someone with an AV fistula?
**1)** Do not carry heavy objects on the extremity **2)** Do not sleep on or compress the extremity **3)** Monitor for bleeding after dialysis (apply pressure) **4)** Assess function and perfusion Q4H -> Bruit, thrills, distal pulse, capillary refill **5)** No blood pressure taken on affected arm **6)** No blood draws or IVs on affected arm
703
What is the main complication for peritoneal dialysis? How can we prevent this and what should you do if the effulent is cloudy and opaque?
**Complicaiton:** peritonitis **Prevention:** Sterile insertion and technique when assessing catheter **Clody and opaque effluent:** obtain a culture for labs
704
What is normal urine output per day?
0.5mL/kg/hr or 1-3L/day
705
What amount of urine output would be concerning?
< 30mL/hr or < 500mL/day
706
What is acute kidney injury?
A rapid reduction in kidney function causing an inability to maintain proper fluid and electrolyte balance and acid-base balance
707
What are causes and risk factors for acute kidney injury?
**1)** Decreased perfuion to kidneys - Dehydration - Embolus or thrombus at renal arteries - Sepsis or shock - Myocardial infarction **2)** Damage to kidney tissue - Nephrotoxic medications (aspirin, NSAIDs like ibuprofen and naproxen) - CT contrast - Antibiotics (vancomycin, gentamicin) - Diabetes - Hypertension **3)** Obstruction of urinary output - Kidney stones - Pyelonephritis - Prostate cancer
708
What aspects of urine should you look at during suspected or confirmed AKI?
**1)** Color **2)** Clarity **3)** Amount **4)** Odor **5)** Frequency < 30mL/hr for 2 hours or < 0.5mL/kg/hr = report
709
What should the nurse examine to determine if decreased perfusion is happening in acute kidney injury?
**1)** Low blood pressure, MAP < 65 **2)** High HR **3)** Weak peripheral pulses **4)** Decreased cognition
710
What lab findings would you expect in acute kidney injury?
**1)** Increased creatinine **2)** Increased BUN **3)** High serum osmolality and urine specific gravity **4)** High K+ (metabolic acidosis - low bicarb) **5)** Low GFR **6)** High Phosphate **7)** Low calcium
711
What diagnostics/imaging can you use during acute kidney injury?
**1)** CT **2)** Ultrasound **3)** Kidney biopsy during severe issues
712
How can acute kidney injury be prevented?
**1)** Drink 2-3L of fluid/day **2)** Maintain a normal blood pressure **3)** Reduce nephrotoxic medications **4)** Monitor kidney function and increase fluids during contrast administration (**STOP** medformin 24 hours before contrast) **5)** Redose medications as needed to prevent kidney injury
713
Why would temporary dialysis be used in acute kidney injury?
**1)** To treat symptomatic uremia (decrease in cognition) **2)** High K+ levels, >6.5 **3)** Severe metabolic acidosis < 7.1 pH **4)** Fluid overload
714
What is chronic kidney disease?
Progressive, irreversible, damage to the kidneys altering elimnation that has lasted longer than 3 months
715
What are the 5 stages with GFR of chronic kidney disease?
**1+2)** Often asymptomatic, risk factor reduction; GFR >90 **3)** Some symptoms, strategies to slow progression like ACE inhibitors; GFR 60-89 **4)** Manage complication, dialysis preparation; GFR 30-59 **5)** ESKD - dialysis or kidney transplant necessary; GFR < 30
716
What complications for each category would you expect to see in someone with chronic kidney disease? 1) Kidney 2) Metabolic 3) Cardiac 4) Hematologic 5) Immunity 6) GI 7) Cognitive
**1) Kidney:** fluid overload (crackles, edema, bounding pulse) **2) Metabolic:** Hperkalemia (K+ high); metabolic acidosis (decreased acid secretion), hyperphosphatemia (high phosphate), hypocalcemia (low Ca2+) **3) Cardiac:** hypertension, hyperlipidemia, heart failure, pericarditis **4) Hematologic:** anemia (bleeding or bruising risk) **5) Immunity:** infection risk **6) GI:** N/V, anorexia **7) Cognitive:** changing cognition with advanced disease
717
What is uremia and what are the signs and symptoms?
**Uremia:** azotemia, or the build up of nitrogenous waste in the blood, that causes symptoms **S/S:** **1)** Metallic taste in the mouth **2)** Anorexia **3)** Nausea **4)** Vomiting **5)** Muscle cramps
718
What are risk factors for chronic kidney injury?
**1)** Acute kidney injury **2)** Hypertension **3)** Diabetes
719
What signs and symptoms may be present in chronic kidney injury?
**1) Neuologic:** *lethargy and fatigue*, seizures, coma, upper extremity weakness **2) Cardiovascular:** hypertension, fluid overload **3) Respiratory:** metabolic acidosis causing tachypnea and Kussmal respirations to compsenate **4) Hematologic:** anemia (bruising, bleeding), decreased WBC **5) GI:** anorexia, nausea, vomiting, metallic taste, foul breath **6) GU:** late stage oliguria and anuria **7) Skin:** pruritis, dry skin, yellow/pallor or darkening **8) Musculoskeletal:** weakness, bone pain, fracture **9) Psychosocial:** depression, fatigue, sexual dysfunction
720
What labs or findings are present in chronic kidney injury?
**1) Urinalysis:** early protein, glucose, RBCs, WBCs, and low urine specific gravity **2)** Early hyponatremia **3)** Late hypernatremia (Worsens hypertension and fluid retention); hyperkalemia = dysrhythmias; **4)** Reduced acid secretion = metabolic acidosis **5)** hyperphosphatemia **6)** Hypocalcemia **7)** High BUN and Creatinine **8)** Low GFR
721
How should you treat fluid and electrolyte imbalances in chronic kidney disease?
**1)** Dieurtics **2)** Hemodialysis 3/week 3-4 hours or peritoneal dialysis in ESRD **3)** Fluid status assessment = daily weights, I/O's, fluid overload S/S **4)** Fluid restriction **5)** Monitor electrolytes **6) Medications:** phosphate binders, multivitamins
722
How do you improve cardiac function in chronic kidney disease?
**1)** Control hypertension by using diuretics (thiaizde), Ca2+ channel blockers, ACEIs, beta blockers **2)** Monitor HF S/S
723
How do you improve nutrition in chronic kidney disease?
**1)** Consult a registered dietician **2)** Restrict protein early on d/t difficulty metabolising and excreting it (more is allowed for hemodialysis patients) **3)** Restrict sodium, potassium, and phosphorus **4)** Fluid restrictions **5)** Multivitamins, phosphate binders **6)** Give Ca2+ with vitamin D and iron
724
Phosphate binders: what medication, what does it do, education, side effects
**Medication:** calcium acetate **Action:** prevents absorption of dietary phosporus **Education:** - Take with meals - Do not take within 2 hours of other medications - Take after dialysis - Monitor phosphorus and calcium levels **Side effects: constipation**, weakness, pulse irregularity
725
Parathyroid Hormone Modulator: What medication, what does it do, side effects
**Medication:** Cinacalcet **Action:** Reduces parathyroid hormone to maintain blood levels of Ca2+ and phosphorus **Side effects:** diarrhea, muscle pain
726
Erythropoetin Stimulating Agents: what medication, what does it do, monitoring, side effects
**Medication:** erythropoetin alfa **Action:** Prevents or corrects anemia **Monitor:** high hemoglobin (too high is > 10-11) because it increased blood viscosity **Side effects:** chest pain, high blood pressure, weight gain, swelling, hives