Final Exam

Question 1

What abx are part of penicillins?

Answer 1

Penicillin G, amipicillin/amoxicillin, amoxicillin-clavulanic acid, cloxacillin, and ticarcillin

Question 2

What abx are part of first generation cephalosporins?

Answer 2

Cephalexin/cefadroxil, cefazolin, and cephapirin

Question 3

What abx are part of second generation cephalosporins?

Answer 3

Cefoxitin

Question 4

What abx are part of third generation cephalosporins?

Answer 4

Ceftiofur, cefovecin, and cefpodoxime

Question 5

What abx are part of carbapenems/monobactams?

Answer 5

Imipinem, and meropenem

Question 6

What abx is a glycopeptide abx?

Answer 6

Vancomycin

Question 7

Is bacitracin a B-lactam?

Answer 7

No it is its own category

Question 8

What abx affect the cell membrane?

Answer 8

Polymixin B

Question 9

What abx are tetracyclines?

Answer 9

Oxytetracycline, chlortetracycline, doxycycline and minocycline

Question 10

What abx are amphenicols?

Answer 10

Chloramphenicol and florfenicol

Question 11

What abx are macrolides?

Answer 11

Erythromycin, tylosin, tilmicosin, tulathromycin, and azithromycin/clarithromycin

Question 12

What abx are lincosamides?

Answer 12

Lincomycin, pirlimycin, and clindamycin

Question 13

What are the two streptogramins used together?

Answer 13

Type A and B

Question 14

What abx are aminoglycosides/aminocyclitols?

Answer 14

Gentamicin, amikacin, neomycin, and apramycin/spectinomycin

Question 15

What are the miscellaneous abx that are used against protein synthesis?

Answer 15

Linezolid, mupirocin, fusidic acid, and avilamycin

Question 16

What abx are sulfonamides?

Answer 16

Sulfamethoxine, trimethoprim-sulfadiazine, trimethoprim-sulfamethoxazole, pyrimethamine-sulfadiazine, and sulfasalazine

Question 17

What abx are part of fluoroquinolones?

Answer 17

Enrofloxacin/orbifloxacin/marbofloxacin, pradofloxacin, ciprofloxacin, and danofloxacin

Question 18

What abx are part of nitroimidazoles?

Answer 18

Metronidazole and ronidazole

Question 19

What abx are part of nitrofurans?

Answer 19

Nitrofurantoin and nitrofurazone/furazolidine

Question 20

What are the “other” therapies besides abx?

Answer 20

Methanamine, carbadox, trizEDTA, and silver

Question 21

What abx are used to inhibit cell wall synthesis?

Answer 21

B-lactams (penicillins, cephalosporins, and carbapenems/monobactams), glycopeptides, and bacitracin

Question 22

What abx are used that disrupt protein synthesis?

Answer 22

Tetracyclines, amphenicols, macrolides/lincosamides, aminoglycosides/aminocyclitols, streptogramins, and others

Question 23

What abx disrupt DNA/RNA synthesis?

Answer 23

Sulfonamides and dihydrofolate reductase inhibitors, fluoroquinolones, nitroimidazoles, nitrofurans, rifampin, and novobiocin.

Question 24

What abx are part of B- lactams?

Answer 24

Penicillins, cephalosporins, carbapenems and monobactams

Question 25

When is activity greatest for L-asparaginase?

Answer 25

G1 cell phase

Question 26

What does L-asparaginase treat and whats the main adverse effect?

Answer 26

Lymphoma | Can cause anaphylaxis and pancreatitis

Question 27

What does piroxicam treat?

Answer 27

TCC of the bladder in dogs

Question 28

What are bisphosphonates and alendronate used for?

Answer 28

Adjunct with bone neoplasias and manage hypercalcemia

Question 29

The treatment of lymphoreticular neoplasias by suppressing lymphocytes is done with which drug?

Answer 29

Pred/prednisolone

Question 30

Which drug can cause sterile hemorrhagic cystitis and is a prodrug?

Answer 30

Cyclophosphamide

Question 31

Which drug can be used as an immunosuppressant and treats chronic lymphocytic leukemia?

Answer 31

Chlorambucil

Question 32

Which drug is eliminated by plasma hydrolysis?

Answer 32

Melphalan, also treats MM

Question 33

Which drug can be used to treat CNS neoplasms?

Answer 33

Lomustine (and carmustine)

Question 34

Which drug CANNOT be used in cats because it can cause fatal pulmonary toxicosis?

Answer 34

Cisplatin

Question 35

Which drug is a potent vesicant and can cause a chronic, irreversible, cardiomyopathy in dogs?

Answer 35

Doxorubicin

Question 36

Which drug is a microtubule inhibitor??

Answer 36

Vincristine/vinblastine- also potent vesicant

Question 37

Which drug is an inhibitor of dihydrofolate reductase and is a potentiator for sulonamides?

Answer 37

Methotrexate

Question 38

Which drug is used to treat granulomatous meningoencephalitis?

Answer 38

Cytosine arabinoside

Question 39

Toceranib is used to treat what? and what phase?

Answer 39

Canine mast cell tumors and phase G1