Final Exam Questions

Question 1

Name the species Most commonly affected by white nose syndrome in bats

Answer 1

Little brown bats Northern Long eared bats Tricolored bats

Question 2

Which blood factor triggers anthrax spore germination?

Answer 2

L – alanine in serum

Question 3

In which cells do anthrax bacteria grow?

Answer 3

Macrophages

Question 4

In primates, where the gross findings associated with measles infections?

Answer 4

Facial edema Rash

Question 5

Lyssaviruses. Which glycoprotein is responsible for attachment and pathogenicity?

Answer 5

G glycoprotein

Question 6

Which genotype causes rabies in North America

Answer 6

Genotype one

Question 7

Which species in North America is most commonly found positive for rabies virus?

Answer 7

Big brown bats

Question 8

Which species is responsible for the majority of the Zoomotic rabies transmission in North America?

Answer 8

Silver haired Bats

Question 9

In carnivores infected by canine distemper virus, what is the most common secondary infection?

Answer 9

Toxoplasma

Question 10

Which type of virus causes Aleutian disease in ferrets and mink?

Answer 10

Parvovirus

Question 11

What are the two major diseases caused by pesti virus infection?

Answer 11

BVD Classical swine fever

Question 12

In black footed ferrets infected with canine distemper virus, what is the most common secondary infection?

Answer 12

Coccidiosis

Question 13

Which mineral is necessary for anthrax spore dormancy and survival

Answer 13

Calcium

Question 14

In dogs infected with canine distemper virus, what is the most common secondary infection?

Answer 14

Pneumocystis carnii

Question 15

What are the four broad disease syndromes associated with retroviruses?

Answer 15

1. Malignant tumors 2. Wasting disease 3. Neuro disease 4. Immunodeficiency

Question 16

Important hosts of Tularemia

Answer 16

Lagomorphs, rodents including voles, muskrats, lemmings, hamsters, beavers

Question 17

What are the two important avian paramyxovirus

Answer 17

Newcastle’s disease Avian influenza

Question 18

Which avian diseases are associated with birdfeeders?

Answer 18

Avian pox Salmonella

Question 19

Differential diagnoses for multifocal, small white spots on liver in mammals

Answer 19

Tyzzer’s disease – Clostridium piliforme Yersiniosis – Yersinia pseudorubedculosis Tularemia - Francisella tularensis Less common salmonella/E. coli septicemia

Question 20

Describe the pathogenesis resulting ultimately in death from rabies

Answer 20

Decrease nerve input + apoptosis = organ dysfunction = death

Question 21

What key feature distinguishes Tyzzer’s Disease from Tularemia and Yersiniosis?

Answer 21

No splenic lesions

Question 22

Name the molecular typing used for Mycobacterium

Answer 22

Spoligotyping PCR of 43 conserved segments

Question 23

Why are birds resistant anthrax?

Answer 23

Body temperature is too high for replication

Question 24

Describe anthrax bacteria morphology

Answer 24

Gram-positive Long rod in short chains

Question 25

What triggers anthrax sporulation?

Answer 25

Decreased nutrients Decreased water

Question 26

Why do anthrax spores congregate after flooding?

Answer 26

Hydrophobic surface layers – increased buoyancy – moves up the water table and from water onto vegetation

Question 27

How many known neurotoxins are there for avian botulism? Which are most common?

Answer 27

7 Type C Type E

Question 28

CWD – how does dose affect incubation period?

Answer 28

Increased dose = decreased incubation.

Question 29

What species is responsible for the majority of Canadian zoonotic cases of Tularemia?

Answer 29

Snowshoe hare – hunters

Question 30

Differential diagnoses for 1. myocardial necrosis/infarct 2. Hemorrhage

Answer 30

1. Lead poisoning West Nile virus 2. Duck Plague & Avian cholera

Question 31

Is yersiniosis a zoonotic risk?

Answer 31

Yes – Y. Entercolitica

Question 32

Which avian diseases cause multifocal hepatic necrosis?

Answer 32

Avian cholera ( P. multocida) Avian herpesvirus – should also have hemorrhage Systemic avian pox

Question 33

Name the 4 diseases of feral swine in the US

Answer 33

Brucella suis Trichinellosis Classical swine fever Pseudorabies

Question 34

Which two species cause ringworm in Wild deer?

Answer 34

Microsporidim sp. and Trichophyton verrucosum

Question 35

Define force of infection

Answer 35

Fraction of susceptible population that an infected host can contact and infect per-unit time

Question 36

Which environmental conditions favor mycobacterium survival in the environment?

Answer 36

Cold and damp

Question 37

Which bacteria most often cause secondary infections in white nose syndrome

Answer 37

Hafnia alvei Serratia sp. - chitinase producing

Question 38

Name the fish associated tapeworm

Answer 38

Metorchis conjunctus

Question 39

Diseases leading to Hawaiian bird extinctions

Answer 39

Haemosporidia Avian pox Rats

Question 40

How are botulism toxins activated?

Answer 40

Needs protease/trypsin digestion Increased in autolytic carcasses

Question 41

What virus causes inclusion body hepatitis in raptors?

Answer 41

Columbid herpesvirus one

Question 42

Which two diseases cause explosive die-offs in waterfowl?

Answer 42

Avian botulism – type C Avian cholera – P. multocida

Question 43

What are the three components of hemorrhagic syndrome in EHD/bluetongue infections?

Answer 43

Edema/transudate Thrombosis-necrosis Coagulation-DIC

Question 44

Describe the 2 effects of latitude on hemorrhagic disease in deer

Answer 44

At northern latitudes decreased frequency of outbreaks but increased disease severity

Question 45

Disease characterized by hemorrhagic enteropathy, upper G.I. erosions ulcerations, histology – vasculitis

Answer 45

Adenovirus hemorrhagic disease of deer

Question 46

Lesions associated with adenovirus hemorrhagic disease in Deer

Answer 46

Pulmonary edema Intestinal hemorrhage Necrotizing stomatitis – Vasculitis related

Question 47

Three viruses associated with pulmonary edema and/or hemorrhagic enteropathy in deer

Answer 47

Bluetongue virus Epizootic hemorrhagic disease virus Adenovirus hemorrhagic disease

Question 48

Describe inclusion bodies associated with adenovirus hemorrhagic disease

Answer 48

Endothelial cells Eosinophillic Intracytoplasmic

Question 49

Describe the lesion associated with canine infectious hepatitis in Black Bears

Answer 49

Neutrophilic meningoencephalitis

Question 50

Which two general types of diseases are caused by adeno virus in deer

Answer 50

Hemorrhagic disease Renal epithelial necrosis

Question 51

Etiology of Hepatic necrosis in California sea lions

Answer 51

Adenovirus

Question 52

Main histologic Lesion associated with malignant catarrhal fever

Answer 52

Vasculitis

Question 53

Describe the main lesions in mink with Aleutian disease

Answer 53

Decreased reproductive success We kits Renal failure/ wasting

Question 54

Describe the lesions associated with Aleutian disease in ferrets

Answer 54

Wasting hindlimb ataxia/paresis Nonsuppurative meningoencephalomyelitis

Question 55

Describe the pathogenesis of Aleutian disease

Answer 55

Non- neutralizing AB to AMDV -AB overproduction – increased plasma cells – hyper globulinemia – immuno complex vasculitis and glomerulonephritis

Question 56

What type of virus causes myxomatosis

Answer 56

Poxvirus

Question 57

What type of virus causes rabbit hemorrhagic disease

Answer 57

Calicivirus

Question 58

Which age class survives rabbit hemorrhagic disease And European brown hair syndrome

Answer 58

\< six weeks old

Question 59

Characteristic histology lesions in rabbit hemorrhagic disease

Answer 59

Fibrin thrombi in glomeruli Hepatic necrosis

Question 60

Differentials for hemorrhage from the nose of a rabbit

Answer 60

Rabbit hemorrhagic disease Myxomatosis

Question 61

zoonotic disease associated with hantavirus in rodents

Answer 61

Hemorrhagic fever with renal syndrome

Question 62

Increases in which species' population results in an increased risk of yersiniosis

Answer 62

Muskrats

Question 63

What molecule blocks flea gastrointestinal tracts and results in transmission of plague

Answer 63

Heme

Question 64

Three clinical forms of plague

Answer 64

Bubonic Septicemic Pneumonic

Question 65

Name the disease

Answer 65

myxomatosis

Question 66

Which hemoglutinin subtypes are historically assoc. with high path. Avian Influenza?

Answer 66

H5 H7

Question 67

Avian hosts of St. Louis Encephlitis

Answer 67

House sparrows House finches

Question 68

Important viral disease of whooping cranes

Answer 68

Eastern Equine Encephalitis

Question 69

Virus that causes Bollinger Bodies

Answer 69

Avian Pox Virus

Question 70

Which hemosporidium species does not produce black pigment (hemozoin)?

Answer 70

Leucocytozoan

Question 71

Sarcocystis of ducks

Answer 71

Sarcocystis rileyi

Question 72

2 most important lesions of duck plague

Answer 72

Fibrinonecrotic foci in GI GI Hemorrhage

Question 73

How many hosts does the winter tick have?

Answer 73

One

Question 74

Microparasites - SIR Macroparasite - X

Answer 74

Distribution model

Question 75

Fungal species responsible for white nose syndrome

Answer 75

Geomyces destructans