Final Exam - Study questions Flashcards by Nacher Mohan

What is the suffix for phosphodisterase ED drugs?

-fil

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Ocular SE of -FIL drugs

Retinal Heme
NAION (non-arteritic ischemic optic neuropathy)
Vision Loss
Elevated IOP
Cyanopsia

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Which three drugs will inhibit HMG-COA?

a. Alendronate
b. Tamoxifen
c. Statin
d. Sildenafil
e. Methotrexate

Alendronate(Osteoprosis), Statin (anti-hyperlipidemic) and FIL (ED drugs)

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Which two drugs will increase LDL levels?

Drospirenone (YAZ - contraception/Acne/Dysmenorrhea/Endometriosis/PCOS)
and
-FIL (phosphodiesterase -ED Drug)

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Which of the 4 drugs blocks all 3 pathways of the clotting system?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

Coumadin (Warfarin)

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Which of these drugs is patchy baldness associated with?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

Coumadin (Warfarin)

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Which of these drugs is Diabetic Retinopathy a contraindication with?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

Enoxparin

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Which of the following drugs only affects the first two pathways of the clotting system?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

Enoxaparin

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What are the 4 drugs that interact with Coumadin?

Tetracycline, Fluoroquinolones, Macrolides and Azole Antifungals

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Which two of the following drugs will cause Jaundice?

a. Statin
b. Clopidogrel
c. Coumadin
d. Abciximab

Clopidogrel and Statin

Note: This is largely due to the fact that this drug is actively metabolized in the Liver, thus liver failure may induce further damage. NIACIN will also cause Jaundice

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Which of the following two drugs has fever as an adverse effect?

a. Enoxaparin
b. Clopidogrel
c. Coumadin
d. Abciximab

Enoxaparin and Coumadin

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Which of the following will cause an additive effect on Abciximab/Epitifibatide?

a. Corticosteriods
b. NSAIDs
c. Fluoroquinolones
d. Tetracycliness

NSAID’s - Opthalmic inhibit COX and therefore TXA2

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What are some serious Ocular adverse affects for Statin drugs?

Diploplia, Ptosis, pseudo-CME, blurred vision, Increase IOP, intraocular hemorrhage, cataracts (NSC and PSC)

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Which two drugs work on the PPAR nuclear level?

a. Statin
b. Niacin
c. Coumadin
d. Zone

Statin (hyperlipidemic and Zone drugs (DM drug)

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Which of the following drug will cause CME and toxic amblyopia?

a. Statin
b. Niacin
c. Coumadin
d. Zone

Niacin

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Which drug can be used for DM 1 and 2?

Insulin Glargine

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Which of the following anti lipid drugs will impair renal elimination when interacted with Gancyciclovir?

a. Statin
b. Fibrate
c. Niacin

Fibrate

Note: Gancyclovir interacting with Stiagliptin will also cause renal failure

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Which of the following drugs will display a decrease in metabolism of Metformin, when interacted?

a. Amphotericin
b. Aminoglycosides
c. Acyclovir
d. Cyclosporine

Cyclosporine

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Which of the following drugs, does not have a similar drug interaction to the rest?

a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin

Metformin

Note: Fish oils = increase blood sugar
Cyclosporine = decrease metabolism
Aminoglycoside, Amphotericin, Ganciclovir, Acyclovir = Nephro-toxicity lactic acidosis
Flaxseed = decreased blood sugar

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Which of the following drugs will cause a metallic taste as an adverse effect?

a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin

Metformin

Note: Rash, Lactic Acidosis and Megaloblastic anemia is unique to this drug

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Which of the following drugs may cause photosensitivity but also cause death, as an adverse reaction?

a. Glipizide
b. Piolitazone
c. Sitaliptin
d. Metformin

Glipizide

Note: Causes Cardiovascular death

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Which drug will have a prolonged effect due to NSAID’s?

a. Glipizide
b. Pioglitazone
c. Sitaliptin
d. Metformin

Glipizide

Note: Class is a sulfonurea

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Which drug will possibly give you flu like symptoms?

a. Statin
b. Fibrate
c. Niacin

Fibrate

Note: Fibrate also has muscular side effects as well

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Which of the following is has an adverse effect and causes Diabetic Macular edema and Bladder Cancer?

a. Glipizide
b. Pioglitazone
c. Sitaliptin
d. Metformin

Pioglitazone

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Which two drugs will impair metabolism of Zone drugs? a. Acyclovir b. Azoles c. Beta Blockers d. Trimethoprim e. Flaxseed Oil

Azoles and Trimethoprim

Which of the following drugs should you NOT use when an ocular disease is present? a. Enoxaparin b. Clopidogrel c. Coumadin d. Abciximab

Clopidogrel

Which of the following drugs should not be given to an individual with high cholestrol readings? a. Enoxaparin b. Clopidogrel c. Coumadin d. Abciximab

Coumadin Note: May cause cholesterol embolism

Which of the following drugs can be used for a bacterial infection (H. Pylori) in the eye? a. Estrone b. Tamoxifen c. Coumadin d. Esomeprazole

Esomeprazole

Which of the following drug causes dry mouth and diarrhea? a. Estrone b. Tamoxifen c. Cimetidine d. Esomeprazole

Cimetidine

Which of the following drugs will cause gynecomastia? a. Cimetidine b. Tamoxifen c. Coumadin d. Esomeprazole

Cimetidine

Which of the following drugs does not have any adverse affects? a. Estrone b. Tamoxifen c. Coumadin d. Esomeprazole

Esomeprazole

Which of the following drugs causes Pseudotumor cerebri as an adverse reaction? a. Estrone b. Levothyroxine c. Tamoxifen d. Esomeprazole

Levothyroxine

Which of the followings has an additive affect on Thyroid therapies? a. B-blockers b. Alpha Agonist c. Sympathomimetics d. NSAID's

Sympathomimetics

Which of the following drugs impairs the metabolism of caffeine? a. Cimetidine b. Tamoxifen c. Coumadin d. Esomeprazole

Cimetidine

Which of the following drugs is an indication for Choriocarcinoma? a. Cimetidine b. Tamoxifen c. Promethazine d. Methotrexate

Methotrexate

Which of the following is not an adverse affect of Alendronate? a. Photosensitivity b. Uveitis c. Conjunctivitis d. Scleritis

Conjunctivitis

Which of the following has big issue of producing too much production of vitamin k clotting factor? a. Levothyroxine b. Estrone c. Drospirenone d. Tamoxifen

Estrone

Which of the three are ocular adverse affects of Thyroid drug. a. Ptosis b. Diplopia c. EOM paresis d. Ocular lesions e. Contact lens

Ptosis, Diplopia and EOM

Which of the following drugs, pick 2, causes an intolerance to Contact lenses? a. Estrone b. Estradiol c. Tamoxifen d. Clomiphene

Estrone and Estradiol

Which hormone will induce a further affect of endometrial cancer and invasive breast cancer? a. Estrone b. Estradiol c. Tamoxifen d. Coumadin

Estrone Note: DVT and MI are also part of this black box warning

What type of phasic drug is YAZ? a. monophasic b. diphasic c. triphasic d. four phasic

monophasic

Which type of vitamin will decrease the metabolism of YAZ? a. Vit A b. Vit B c. Vit C d. Vit D

Vit C = Ascorbic Acid

Which of the following is an additive to hyperkalemia for contraception drugs? a. Steroids b. Tetracycline c. Fluoroquinolones d. NSAID's

NSAID's

Severe adverse affects of Tamoxifen? a. Stroke b. Pancytopenia c. Cataracts d. Thromboembolism e. Retinopathy f. All of the above

All of the above

Which of the following drugs will increase the levels of Cyclosporine, Steroids and Oxycodone? a. Tamoxifen b. Estradiol c. Esterone d. Yaz

Tamoxifen

Which of the following two will decrease the effectiveness of Tamoxifen? a. Fluoroquinolines b. Statin drugs c. Macrolides d. Chlorpheiramine

Macrolide and Chlorpheiramine

What type of affect will occur when NSAIDs and Methotrexate are combined? a. Increase the affect of both b. Decrease their affect c. Allergy reaction d. Myelosuppression

Fatal myelosuppression

True or False. Bone marrow density will decrease as you take Methotrexate.

True

Which of the following will cause neurotoxcity a. Pemetrexed b. Methotrexate c. Trimethoprim d. Pyrimethamine

All of these. They are all anti metabolites

What would you take with central antiviral agents to lower the pH content? a. Milk b. Water c. Coca Cola d. Cocaine

Coca Cola - it will lower the pH level considerably faster

At which level of the H2 receptor will only be affective? a. Alpha level b. Beta level c. Kappa level d. Basal Level

Basal level

Match the following with hyperthyroidism and hypothyroidism. a. Bradycardia b. Tachycardia

``` Hyper = Tachy Hypo = Brady ```

True or False. Estrogen dosing for menopause is significantly higher and safer than contraception.

False. Estrogen does for menopause is LOWER and safer than contraception

What is the most potent estrogen producer?

Estradiol Note: Estrone is a metabolite of Estradiol and will be 1/3 potent as Estradiol

Which gender does osteoporosis occur in the most?

Female Note: Cholesterol build up

What are the two most lethal cancer's that can spread to the eye?

Lung and Breast

What are the top 4 cancer deaths in males?

1. Lung 2. Prostate 3. Colon 4. Pancreas

What are the top 4 cancer deaths in females?

1. Lung 2. Breast 3. Colon 4. Pancreas

What are the highest amount of new cases in males?

Prostate

What are the highest amount of new cases in females?

Breast

Which type of drug also has the similar affects as chemotherapy of vomitting, nausea and chemical structure of the drug?

Anti-psychotics

Which is correct? a. Arterial thrombosis = Coagulation Cascade b. Arterial thrombosis = Platlet rich clot

b. Arterial thrombosis = Platlet rich clot

Which is correct? a. Venous thrombosis = Coagulation Cascade b. Venous thrombosis = Platlet rich clot

Venous thrombosis = Coagulation Cascade

Which of the two pathways, Extrinsic or Intrinsic, causes a thrombin burst?

Extrinsic - synthesis of vitamin K coagulation factors

Which of the two pathways, Extrinsic or Intrinsic, is important in the inflammatory pathway?

Intrinsic

What of the following is a contraindication for a statin drug? a. Apple juice b. Orange Juice c. Grapefruit juice d. Purple Drank

Grapefruit juice

True or False. Coronary heart disease causes 1/2 deaths in all of the US

True

True or False. Type 2 DM is most common in Overweight, Non-caucasian and Over 40 years of age.

True

Which ethnic group has the greatest risk for insulin resistance?

Latino's

Which ethnic group has the greatest for Beta cell dysfunction?

East Asian

What is the most common side effect from Anti HTN?

Headache

Which structure is the most similar to Morphine? a. Hydrocodon b. Codeine c. Heroine d. NSAID's

Codeine Note: NSAID's are the most different

What is the most common side affect of Lisinopril?

Cough with plegm

Lisinopril is associated with what ocular side effects?

Ocular surface issues, Dry eye (when combined with BBlockers)

Amlodipine is associated with what ocular issues?

Diplopia, Pain, and Conjunctivitis (when combined with Lisinopril)

Terazosin is associated with what ocular side effects?

Catract surgery and Intraoperative floppy iris syndrome and Pain

Metaprolol/Atenolol is associated with what ocular issues?

Decrease IOP, Glaucoma progression, Opth Decong anatagonist

Furosemide is inhibits reabsorption of NaCl at what parts of the kidney?

Proximal and Distal

What drugs are hypersensitive to Sulfonamides?

Furosemide, HCTZ diuretic

What major ocular issue is associated with HCTZ diuretic?

Angle Closeure Glaucoma

Which drug is associated with Lupus Erythematosus?

Hydralazine

Escitalopram is associated with what ocular issues?

Ptosis, Conjunctivitis, Diplopia, Blur and DRY EYE!

Which of the following is not an SSRI? a. Fluoxetine b. Duloxetine c. Escitalopram d. Sertraline

Duloxetine

Which typical anti-pshycotic drug is associated with cataracts?

Qutiapine

Which alzheimer drug inactivates ACHesterases?

Donepizil

Which drug is associated with Parkinsons?

Sinemet

Celecoxib has 4 major side effects. Name them.

Bleeding, Ulcer, Stroke and Sulfa allergy

Which drug is associated with respiratory disease, that also has a side-effect causing conjunctivitis

Tramadol

What are the 3 ocular side effects of Fluticasone?

Cataracts, Glaucoma and Increase IOP

Name the 5 ocular issues related to Mometasone.

Increase IOP, Glaucoma, HSV infection, Cataracts and Vision changes