Final Only - Weller - STDs Flashcards
(37 cards)
Bacterial STIs? 5
Neisseria gonorrhoeae
Syphilis
Chlamydia trachomatis
Chancroid
Klebsiella
Viral STIs?
HIV
Genital warts/HPV
Herpes Viruses
Hep B
Hep C
Parasitic STIs?
Trichomonas vaginalis
Sarcoptes scabiei
Syndromes from STIs?
Pelvic inflammatory disease
Epididymis
What is urethritis?
Inflammation of urethra
-Common STIs in men
What is cervicitis?
Inflammation of the uterine cervix
What causes gonorrhea?
Neisseria gonorrhoaea
-G- diplodocus bacteria
—70-80% male to female transition and 20-30% female to male transition
What are symptoms of gonorrhea?
Asymptomatic to mildly symptomatic
Men
-Gonococcal urethritis is the most common manifestation of symptomatic infection
Women
-Discharge, abnormal bleeding, anorectal discomfort
What is the gold standard for dx of gonorrhea?
Tx?
Culture or PCR
Ceftriaxone, Cefpodoxime, Ciprofloxacin, Cefixime
What is chlamydia trachomatis?
Obligate intracellular bacteria - G- bacterium
PCR test
Tx - Azithromycin or doxycycline
What is haemophilus ducreyi?
G- coccobacillus
PCR is gold standard
Tx - Azithromycin, Ceftriaxone, Ciprofloxacin, Erythromycin
Tell me about syphilis.
Caused by spirochete Treponema pallidum
-Acquired sexually
Symptoms
- Primary - Chancre
- Secondary - Rash, swollen glands
Detection
-PCR
Tx
-Penicillin G benzathine
Tell me about Klebsiella granulomatis.
G-, rod-shaped bacterium
Symptoms (Usually in genitals)
- Bleeding ulcers
- Raised irregular edge of ulcer
- Necrotic bad smell
- Sclerotic lesion
Detection
- Donovan bodies
- PCR
Tx
-Azithromycin, erythromycin, doxycycline
Tell me about Trichomonas vaginalis.
Flagellated parasite
*Accounts for almost half of all curable STDs worldwide
Symptoms
-Infectious vaginitis
Features
- Wet mount
- PCR
Tx
-Single dose of metronidazole
Tell me about sarcoptes scabiei.
Itch mite
Symptoms
-Itching and no sleep
Features
-Burrows seen on skin scrapings
Tx
-5% permethrin cream
Tell me about genital warts.
HPV
*100 different types
Symptoms
- Burning, itching, pain, and fullness
- Many pts are asymptomatic
Tx
- Surgery
- Liquid nitrogen
- Podofilox, podophyllin resin
Tell me about herpes simplex virus types 1 and 2.
HSV-1 - Cold sores - 80% of population are carriers
HSV-2 - Genital herpes
Symptoms
-Primary Infection at mucosal site of inoculation w/ retrograde infection. Following resolution of primary infection, HSV remains in a latent state w/ intermittent reactivation at mucosal sites
Features
-PCR
Tx
- Antiviral therapy for initial genital herpes
- Daily suppressive therapy reduces frequency of recurrences
T/F - HSV-2 and HIV are not on the CDC reportable infectious disease list. Gonorrhea and chlamydia are.
TRUE
What are these viruses?
Human T cell lymphotropic virus (HTLV-1 and 2)
Hep C
Hep B (Hep D)
CMV
EBV
Molluscum contagiosum virus
Other sexually transmitted viruses
What is PID?
Pelvic Inflammatory Disease
Tell me about PID.
From N gonorrhoeae and C trachomatis
Symptoms
-Ascends from cervix or vagina to involve the endometrium and/or Fallopian tubes
—Infection can extend beyond the reproductive tract
Tx
-Ceftriaxone, doxycycline, metronidazole
Tell me about epididymitis.
C trachomatis, n gonorrhoae
Symptoms
-Unilateral scrotal pain, tenderness, swelling, fever
Tx
-Ceftriaxone and then doxycycline
Syphilis
Incubation period?
Early primary lesion?
No. Of lesions?
9-90 days
Papule
1
Herpes
Incubation period?
Early primary lesion?
No. Of lesions?
2-7 days
Vesicle
Multiple
