Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Phar 764 > Final Quiz: Anemia > Flashcards

Final Quiz: Anemia Flashcards

(47 cards)

Start Studying
1
Q

Anemic Hgb Men

A

Under 13

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Anemic Hgb Women

A

Under 12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Severely anemic Hgb Men/Women

A

7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Treatment for severe acute anemia

A

Give blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Acute presentation of anemia

A

Heart-related problems

Fatigue-related problems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Macrocytic
Normocytic
Microcytic

A

> 100
80-100
<100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Low TSAT in acute anemia

A

Less than 20%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

TIBC if iron-related

A

Over 400

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

TIBC if not iron-related

A

Less than 250

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Normal Ferratin and change seen in iron-deficient anemia

A

100-200 : will be decreased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Normal Retics

A

1%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Normal MMA and change seen in B-12 deficiency

A

0.07-0.27 : will be elevated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Normal Homocysteine and change seen in B-12 AND Folate deficiency

A

Less than 15 : will be elevated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Site of iron absorption

A

Duodenum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Reasons for decreased Iron-absorption

A 
Duodenum removed
Enteritis
Chelation
- Di-valent cations
- Tetras/FQ/PCN
- Cholestyramine
Increased pH
- Achlorhydria
- Acid reducing agents
Levodopa/Methyldopa
Levothyroxine
Mycophenolate
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Reasons for increased Iron-requirements

A 
Bleeding (including menstruation)
Rapid growth
- Infants
- Pregnancy
- Lactation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Progression of Iron-imbalance

A

Stores reduced : decreased Ferratin
Stores depleted : decraesed TSAT, increased TBIC
Anemic : Hgb less than normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Signs of Iron-deficiency

A 
Glossitis (tongue)
Angular Cheilitis (mouth)
Koilnychia (nails)
Blue sclera
Pica
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Oral Iron products and strengths

Study These Flashcards
A

Ferrous Sulfate : 65mg elem. 20%
Ferrous Gluconate : 35mg elem. 11%
Ferrous Fumarate : 99mg elem. 33%

20
Q

SE’s from Oral Iron products

Study These Flashcards
A 
Constipation
Nausea
Diarrhea
Abdominal cramping
Dark stools*
21
Q

Why are practitioners beginning to recommend q48hr dosing for Oral Iron products?

Study These Flashcards
A

Hepcidin release in response to iron doses

- Decreases absorption for 48 hours

22
Q

Source of Iron

Study These Flashcards
A

Anything with blood in it
Veggies
Nuts
Etc.

23
Q

Source of Folate

Study These Flashcards
A

Green leafy veggies

24
Q

Source of B12

Study These Flashcards
A

Animal products basically

25
Main differences in symptoms between Folate and B12 deficiencies
Neurological symptoms with B12 deficiency only.
26
What two drugs require Folate supplementation?
Methotrexate | Sulfasalazine
27
Folate replacement therapy
1 mg PO daily ONLY if you have ruled out B12 deficiency
28
What is IFa test used for?
To rule in or out Pernicious Anemia
29
B12 replacement therapy if no neuro symptoms
1 mg PO daily
30
B12 replacement therapy if + neuro symptoms
1 mg IM q48hr for 2 weeks Then 1 mg IM monthly
31
Most common cause of chronic anemia
CKD leading to decreased EPO production
32
When is Iron-replacement therapy indicated in CKD patients?
When TSAT /< 30% regardless of +/- ESA
33
Typical oral/IV iron dose in CDK patients
About 1,000mg elemental iron in both
34
When to use caution with IV iron?
If patient has active infection.
35
Iron Dextran
25mg test dose | 100mg x 10
36
When to hold iron therapy?
If TSAT > 50%
37
INFeD
+/- 25mg test dose | 1g over 8hrs
38
IV Ferric Gluconate
125mg x 8
39
IV Iron Sucrose
100-500 over 30min-4hr x 10
40
When are blood tranfusions warranted?
If Hgb < 7 or It's really low and they are symptomatic
41
When to consider ESA therapy
If Hgb < 10 AFTER or along with Iron replacement
42
ESA therapeutic goal
Hgb 10-11
43
Darbapoetin initial dose
0. 45 mcg/kg monthly - IV if on dialysis - SQ if not on dialysis
44
Epoetin alfa initial dose
50-100 units/kg/dose... - 3 times weekly IV if on dialysis - Weekly SQ if not on dialysis
45
ESA-agent SE's
Hypertension* | Thrombosis
46
ESA agent conversion rules
If Epoetin 3xweekly -> Darba weekly If Epoetin 1xweekly -> Darba bi-weekly - Multiply Epoetin dose by 2 before converting
47
ESA Resistance: Definition and Risk Factors
Definition: requiring more than 150 u/kg ESA 3xweekly. Risk Factors: - Iron deficient - Aluminum tox. (decreases EPO prod.)

Phar 764 (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions