Final Review Flashcards by Brittany Hansel

MC ADR with interferons

HA in 75%

Depression in 60%

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Ribavirin can be used to treat Hepatitis ___

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Timeline for protease inhibitors in treatment of Hep C

Telaprevir (Incivek) first 12 wks then stopped
Bocepravir (Victrelis) week 4 and onward
*always with ribavirin * peginterferon

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recommended regimen for treatment of HIV/AIDS

viread +emtriva= Truvada

Isentress

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What herpres medication can be PO, topical, or IV?

Acyclovir

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Prevention of RSV with

Palivizumab (Synagis)

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Prevention of rotavirus with

RotaTeq
live, oral pentavalent vaccine
3 dose regimen given 6-32weeks

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multidrug resistant TB can use

Bedaquin (Sirturo)

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What TB drug carries risk of optic neuritis?

Ethambutol

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Active TB treatment profile

Rifampin x9m
Isoniazide x9m
Pyrazinamide x8w
Ethambutol x8w

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Chloroquine is a

4-Aminoquinoline

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Quinine sulfate & mefloquine are

4-Methanolquinolones

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Primaquine is an

8-Aminoquinolone

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Malarone is a

anti-folate

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Antimicrobials that can be used as antimalarials

Tetracycline
Doxycycline
Clindamycin

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MOA of metronidazole

interacts with DNA and loss of helical structure

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What should be done when using Amphotericin B

pretreat with acetaminophen and corticosteroid

Mineralcorticoids include

Deoxycorticosterone (Percoten V)

Fludrocortisone (Florinef)

Only notable s/e of adrenergic agonists

Mirabegron (Myrebetriq)

HTN

watch for QTC elongation in pts with hx

antimuscarinics/anticholinergics worsen what type of urinary incontinence

over flow

Don’t use antimuscarinics in

GI obstruction
peptic ulcer disease
asthma
parkinsons

….ateride

5 alpha reductase inhibitor

….nafil

Tadalafil (Cialis)

Phosphodiesterase 5 inhibitor

blue vision associated with Viagra and phosphodiesterase 5 inhibitor class is dt

PDE5 Inhibitor

Tamoxifen (Nolvadex) is a

selective estrogen receptor modulator

Anastrozole (Arimidex) is a

aromatase inhibitor

Name an anti-HER2 agent

Tratuzumab (Herceptin) Lapatinib (Tykerb) Pertuzumab (Perjeta)

who is a candidate for aromatase inhibitor

not if intact ovaries! | good for post-menopausal women

notable ADR of ribavirin/ribasphere

hemolytic anemia

name an neuraminidase inhibitor for PO and inhalation routes respectively

PO: Oseltamivir (Tamiflu) Inhalation: Zanamivir (Relenza)

Black box warning for Telaprevir (Incivek) | what would you be treating?

SJS | Hep C, first 12 weeks in combo with peginterferon & ribavirin

In general HIV/AIDS drugs commonly interact with other drugs via

CYP3A(4)

Generally best vehicle for derm

ointments | -oil in water emulsions MC

Dermatologic topical corticosteroid affects

antiinflam immunosupression of humoral factors Antiproliferative Vasconstriction

Most potent corticosteroids

Class 1: Clobetasol proprionate Diflorasone diacetate Halobetasol proprionate

What diseases are highly responsive to corticosteroids

Psoriasis (intertriginous) atopic dermatitis (esp kids) seborrheic dermatitis Intertrigo

Adapalene cream is a

retinoid

First line treatment for acne

Benzoyl peroxide

ADRs of benzoyl peroxide

``` Peeling Stinging Dryness Erythema Contact dermatitis ```

Antibiotics for treatment of burns

Mafenide | *Silver sulfadiazine