final sample questions

Question 1

which of the following is true about synthesis-dependent strand annealing (SDSA) and non-homologous end-joining (NHEJ)?

a. SDSA is more error-prone than NHEJ
b. SDSA can be used at any phase of the mitotic cell cycle
c. SDSA requires an intact chromatid to be used as a template for repair
d. NHEJ can only be used to repair single-stranded breaks
e. a and b

Answer 1

c. SDSA requires an intact chromatid to be used as a template for repair

Question 1

choose the correct statement about chromosomal rearrangement.

a. chromosomal rearrangements can occur by crossing-over between repetitive DNA elements
b. translocations involve a chromosome break and a joining of ends in the opposite orientation
c. nonallelic homologous recombination (NAHR) may produce duplications or deletions, but never inversions
d. translocations require a duplication of a portion of a chromosome
e. none of the above

Answer 1

a. chromosomal rearrangements can occur by crossing-over between repetitive DNA elements