Finals Drug List Flashcards

(62 cards)

1
Q

cetirizine

A

allergy (H1 antagonist)

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2
Q

fingolimod

A

multiple sclerosis (S1P agonist)

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3
Q

formorterol

A

asthma (b2 agonist)

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4
Q

montelukast

A

asthma (LTD4 antagonist)

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5
Q

phenylephrine

A

nasal decongestant (a1 agonist)

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6
Q

penicillin

A

antibiotic (ADR: anaphylaxis)

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7
Q

NSAIDs

A

ibuprofen (ADR: nephrotoxicity)

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8
Q

corticosteroids

A

ADR: hypothalamus-pituitary-adrenal (HPA) axis insufficiency crisis

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9
Q

antihistamines

A

ADR: drowsiness, impaired coordination and alertness

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10
Q

codeine

A

opiates (ADR: flushing, urticaria, red man syndrome)

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11
Q

cetirizine

A

2nd gen antihistamine

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12
Q

loratadine

A

2nd gen antihistamine

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13
Q

fexofenadine

A

2nd gen antihistamine

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14
Q

diphenhydramine

A

1st gen antihistamine

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15
Q

promethazine

A

1st gen antihistamine

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16
Q

chlorpheniramine

A

1st gen antihistamine

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17
Q

aspirin

A

COX-1 selective inhibitor (ADR: bleeding, asthma, reye’s syndrome)

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18
Q

ibuprofen

A

COX-1 selective inhibitor

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19
Q

naproxen

A

COX-1 selective inhibitor

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20
Q

celecoxib

A

COX-2 selective inhibitor

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21
Q

paracetamol

A

COX-3 selective inhibitor (CNS)

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22
Q

prednisone

A

cortisone + 1,2 db (high DOA, low water retention)

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23
Q

prednisolone

A

hydrocortisone (cortisol) + 1,2 db (high DOA, low water retention)

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24
Q

methylprednisolone

A

prednisolone + 6-methyl (high DOA, no water retention)

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25
dexamethasone
triamcinolone (methylprednisolone + 9-F) + 16-methyl (highest DOA, very potent, no water retention)
26
ciclosporin
calcineurin inhibitor
27
sirolimus
mTOR inhibitor
28
azathioprine
cytotoxic agent
29
mycophenolate mofetil (MMF)
cytotoxic agent
30
fingolimod
S1P receptor agonist (multiple sclerosis)
31
formorterol
LABA (bronchodilator)
32
salbutamol
SABA (bronchodilator)
33
ipratropium bromide
SAMA (bronchodilator) muscarinic antagonist
34
tiotropium bromide
LAMA (bronchodilator)
35
theophylline
Oral-SR (inhibit PDE + block Adenosine receptor)
36
fluticasone
ICS (anti-inflammatory)
37
montelukast
LTRA (anti-inflammatory)
38
sildenafil citrate
PDE 5 inhibitor
39
tadalafil
PDE 5 inhibitor
40
roflumilast
PDE 4 inhibitor (COPD)
41
nitroglycerine
PDE 5 inhibitor (angina)
42
nitroprusside
PDE 5 inhibitor (anti-hypertensive)
43
hemicholinium
inhibit choline uptake, reduce ACh synthesis
44
vesamicol
VAChT inhibitor (block transport of ACh into vesicles)
45
botulinum toxin (botox)
prevent ACh release (dystonia, cosmetics)
46
pralidoxime
cholinesterase (AChE) reactivators (reduce ACh)
47
atropine
non-selective muscarinic antagonist (blocks all muscarinic receptors)
48
bethanecol
urinary retention, GI hypotonia
49
pilocarpine
glaucoma
50
succinylcholine
muscle relaxant (rapid endotracheal intubation, depolarizing blocker)
51
pancuronium
muscle relaxant, paralysis (non-depolarizing competitive blockers)
52
anticholinerases
AChE inhibitors, increase ACh Erdophonium (SA), Neostigmine (IA), Pyridostigmine (IA), Parathion (LA)
53
norepineprhine/epinephrine
a/b agonist (anaphylactic shock, cardiac arrest)
54
salbutamol
b2 agonist (bronchodilator, asthma, premature labour)
55
phenylephrine
a1 agonist (vasoconstriction, nasal decongestant)
56
clonidine
a2 partial agonist (hypertension, migraine)
57
propanolol
non-selective b antagonist (angina, hypertension, cardiac dysrythmia)
58
a-methyl-p-tyrosine
tyrosine hydroxylase inhibitor (phaechromocytoma)
59
reserpine
VMAT inhibitor,reduce NA - block vesicular uptake of NA, remain in cytoplasm>degraded (hypertension, schizophrenia)
60
amphetamine/ephedrine/tyramine
increase NA release without depolarizing membrane
61
cocaine
reduce reuptake of NA into cytoplasm
62
moclobemide
MAO inhibitor- reduce NA breakdown (antidepressant)