Finals formulation Flashcards

1
Q

Sodium acetate
sodium citrate
sodium phosphate
Lactate

A

Buffer

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2
Q

benzyl alcohol
chlorbutanol
phenol
thiomersal
methylparaben
propylparaben
L methionine

A

Preservative

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3
Q

mannitol
sodium chloride
glycerin
glycerol
glycine

A

tonicity adjusting agent
mannitol - cryoprotectant

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4
Q

ethanol
glycerin
glycerol
glycine
PEG
propylene glycol
sesame oil

A

solvent

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5
Q

polysorbate 20 and 80

A

surfactant

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6
Q

cyclodextrin
glyceryl monooleate
ethanol
propylene glycol

A

permeation enhancer
glyceryl monooleate - bioadhesive, sustained release agent, surfactant
ethanol, propylene glycol - solvent

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7
Q

CMC, HPMC

A

Viscosity modifiers, matrix polymer

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8
Q

hyaluronate sodium

A

viscosity modifier, matrix polymer, humectant

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9
Q

calcium alginate

A

viscosity modifier, matrix polymer, adhesive

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10
Q

carbomer
polymethyl vinyl etherimaleic anhydrate

A

viscosity modifier, adhesive

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11
Q

povidone

A

polymer rate limiting membrane

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12
Q

silicone

A

adhesive

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