First 10 Flashcards

(30 cards)

1
Q

What is the function of the thymus gland?

A

Matures T-cells.

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2
Q

What is the function of Peyers Patches? Which organ do they protect?

A

Function to destroy intestinal bacteria. They protect the intestine.

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3
Q

What is the function of the spleen?

A
  • Filters blood
  • Recycles red blood cells
  • Activates white blood cells
  • Initiates immune responses
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3
Q

How is bone marrow involved in immunity?

A

Produces the white blood cells needed for immunity
Site of maturation for B-cells

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4
Q

Which 2 types of lymphocytes are found in lymphatic tissue?

A

T cells and B cells.

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5
Q

What is the pathway of the flow of lymph?

A

Lymphatic capillaries → Lymphatic vessels → Lymph nodes → Larger lymphatic vessels → Lymphatic trunks → Lymphatic ducts → Subclavian veins (into bloodstream).

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6
Q

What are the primary and secondary lymphatic organs/structures?

A

Primary lymphatic organs: Thymus, Red bone marrow

Secondary lymphatic:
Lymph nodes, Spleen, Tonsils
MALT (mucosa-associated lymphatic tissue)

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7
Q

Which lymphatic duct is responsible for draining most of the body?

A

thoracic duct

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8
Q

Where are there major clusters of lymph nodes?

A

Neck
Armpits
Groin
Chest
Abdomen

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9
Q

What are the main functions of the lymphatic system?

A

Fluid Balance
Immune Defense
Fat Absorption
Waste Removal

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10
Q

What determines a persons blood type?

A

A person’s blood type is determined by specific antigens present or absent on the surface of their red blood cells.

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11
Q

What blood is the universal donor and what blood type is the universal acceptor for transfusions?

A

The universal donor blood type for red blood cell transfusions is O negative (O−).

The universal recipient blood type is AB positive (AB⁺).

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12
Q

When testing a persons blood type, the blood will react with the antibody-reagents for what present on the red blood cells?

A

antigens

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13
Q

In blood typing what is the difference between antigens and antibodies?

A

Antigens:
- Surface markers on red blood cells determine blood type
Antibodies:
- Proteins in blood plasma that react to specific antigens

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14
Q

Which lymphatic organ shrinks as we age?

A

The thymus

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15
Q

What is lymph?

A

Lymph is a clear fluid that circulates through the lymphatic system. It originates from interstitial fluid—the fluid that surrounds the body’s cells—which enters lymphatic capillaries. Lymph contains white blood cells (especially lymphocytes), proteins, fats, and waste products. It plays a crucial role in maintaining fluid balance, absorbing dietary fats, and supporting immune function by transporting lymphocytes and filtering pathogens through lymph nodes.

16
Q

What lymphoid structures try to trap and filter out pathogens that enter through the nose or mouth?

A

Tonsils and adenoids are lymphoid structures that trap and filter pathogens entering through the nose and mouth.

17
Q

Which component of the lymphatic system directly connects to and drains lymph back into the circulatory system?

A

The lymphatic ducts—specifically, the thoracic duct and the right lymphatic duct—are the components of the lymphatic system that directly connect to and drain lymph back into the circulatory system.

18
Q

Which lymphocyte is matured in bone marrow?

A

B lymphocytes (B cells) mature in the bone marrow.

19
Q

What is the difference between memory B cells and plasma B cells?

A

Plasma B-Cells give an undifferentiated response, memory B cells remember

20
Q

What are the immune systems 3 lines of defense in order?

A

First Line of Defense – Physical and Chemical Barriers
These are external defenses that prevent pathogens from entering the body. They include:
Skin: Acts as a physical barrier.
Mucous membranes: Trap pathogens in the respiratory and digestive tracts.
Secretions: Such as saliva, tears, and stomach acid, which contain enzymes and acids that neutralize or destroy pathogens.
Second Line of Defense – Innate Immune Response
If pathogens bypass the first line, the innate immune system responds quickly and non-specifically. Key components include:
Phagocytic cells: Such as macrophages and neutrophils that engulf and destroy invaders.
Third Line of Defense – Adaptive Immune Response
B lymphocytes (B cells): Produce antibodies that target specific antigens.
T lymphocytes (T cells): Include helper T cells that assist other immune cells and cytotoxic T cells that kill infected cells.

21
Q

Which lymphatic duct drains lymph from the majority of the body?

A

thoracic duct

22
Q

What process tries to stop the spread of a pathogen at its point of entry into the body?

A

Innate immune system.

23
Q

How do antibodies attack a foreign pathogen?

A

Tags the pathogen for destruction, neutralizes it, and activates the complement system.

24
What is the difference between humoral immunity and cell mediated immunity?
Humoral Immunity: Provides rapid response. Mediated by B cells. Targets extracellular pathogens Cell-Mediated Immunity: Mediated by T cells. Provides slower response. Targets infected or abnormal cells.
25
How is innate immunity different from adaptive immunity?
Innate immunity: - Body's first line of defense -- Rapid, non-specific response - It includes physical barriers like skin, immune cells such as neutrophils and macrophages, and proteins like cytokines and complement. - Does not retain memory of past encounters. Adaptive immunity: - specialized, slower response - It involves lymphocytes—B cells that produce antibodies and T cells that target infected cells. - creates memory cells
26
This condition is characterized by a weakened or absent immune system.
Primary Immunodeficiency Disorders: - Inherited and present from birth. - genetic defects - T cells, B cells, or phagocytes. - Examples include Severe Combined Immunodeficiency (SCID) and Common Variable Immunodeficiency (CVID) . Secondary (Acquired) Immunodeficiency Disorders: - Develop later in life due to external factors - Common causes include infections like HIV/AIDS, certain cancers, malnutrition, and the use of immunosuppressive medications .
27
What is the difference between primary and secondary immunodeficiency? Give an example of each
Primary immunodeficiency: - genetic disorder present from birth - An example is Severe Combined Immunodeficiency (SCID), where both T and B lymphocytes are absent or nonfunctional. Secondary immunodeficiency: - acquired later in life due to factors like infections, medications, or malnutrition. - A well-known example is Acquired Immunodeficiency Syndrome (AIDS), caused by the HIV virus, which attacks CD4+ T cells.
28
Disorders where the immune system incorrectly attacks your own cells are called-
Rheumatoid arthritis: Affects joints, causing inflammation and pain. Systemic lupus erythematosus (lupus): Affects skin, joints, kidneys, and other organs, leading to widespread inflammation.
29
How is Hodgkins lymphoma different from non-Hodgkins?
Hodgkins lymphoma is characterized by the presence of Reed-Sternberg cells, while non Hodgkins lymphoma lacks these cells.