Flea Control Products Flashcards
(17 cards)
What is the mechanism of action of pyrethrins?
Where on the neuron does it act?
Increases Na permeability along the axon, leading to hypersensitivity and death
What are some advantages of using pyrethrins?
Fairly safe and can be used on cats and puppies
Kills fleas quickly
What are some disadvantages of using pyrethrins?
Inactivated by UV light
Short duration of action
What are some advantages of pyrethroids?
Binds to the skin and hair
More photostable, longer duration of action (compare to pyrethrins)
Repels fleas, ticks, and mosquitos if greater than 2%
What are some disadvantages of pyrethroids?
Increased toxicity- g__reater than 0.5% is toxic to cats
Washed off during bathing
Which products contain permethrin as an active ingredient?
Advantix II (55%)
Activivyl Plus
Vectra 3D (33%)
Deltamethrin is commerically available in which form?
What is a disadvantage of this product?
As a collar lasting 6 months
Can cause local irritation
Deltamethrin is effective against which types of ectoparasites?
Kills fleas and ticks
Repels mosquitos
What is the mechanism of action of metaflumizone?
Blocks voltage dependent Na channels on the axon, interrupting nerve impulses
Results in flea paralysis and death
Which product containing metaflumizone was discontinued in the United States?
ProMeris
What is the mechanism of action of indoxacarb?
Blocks voltage dependent Na channels on the axon, interrupting nerve impulses
Results in flea paralysis and death
What are the advantages of indoxacarb?
Has to be bioactivated in the flea to be effective- safe for mammals
Water-safe
What is the mechanism of action of fipronil?
Inhibits GABA-gated chloride channels, leading to axonal hyperexcitation
What are the advantages of Frontline Plus
(contains fipronil and methoprene)?
Concentrates in the sebaceous glands
Photo-sable, water immersion does not change efficacy
Can be used in puppies, kittens, and cats
Combines an adulticide and IGR, effective against ticks
What are the disadvantages of Frontline Plus
(contains fipronil and methoprene)?
Does not repel
Medicated shampoos decrease efficacy
Field reports of decreased efficacy
True or false: No oral flea-control product can act as a repellant.
True. In order for an oral product to work, fleas have to take a blood meal.
What is the mechanism of fluralaner, the active ingredient in Bravecto?
Selectively inhibits GABA and L-glutamate-gated chloride channels
