Flucticasona Flashcards

1
Q

MECANISMO DE ACCIÓN

A

Agonista de receptores glucocorticoides, que induce proteínas como lipocortina 1, el receptor adrenal β 2 y la endopeptidasa neutral. También inhibe la producción/secreción de mediadores celulares

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2
Q

INDICACIONES

A

Asma
EPOC
Rinitis alérgica y no alérgica

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3
Q

Pk

A

Inhalada, nasal y tópica
M: hepático CYP3A4
E: heces y renal

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4
Q

RAM

A
Candidiasis oral y faríngea
Neumonía
Bronquitis
Cefalea
Ronquera
Epistaxis
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5
Q

INTERACCIONES

A

Tripanavir: ↑ niveles plasmáticos de fluticasona y ↓ (plasmáticas de cortisol)

Atazanavir: Posible acumulación de fluticasona con aumento de su toxicidad

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6
Q

PRECAUCIONES

A
Candidiasis faríngea y oral
Cataratas
Cirugía
Crisis asmática
DM
Espasmo bronquial
Glaucoma 
HTA
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7
Q

CONTRAINDICACIONES

A

Alergia a corticoides

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8
Q

🤰

A

C

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