Fluid and Electrolyte balance Flashcards
(116 cards)
What is the primary requirement for proper functioning of all body systems?
Fluid and electrolyte balance (Homeostasis)
Homeostasis is crucial for maintaining stable internal conditions in the body.
What percentage of body fluid is intracellular fluid (ICF)?
40%
ICF is the fluid located inside cells.
What percentage of body fluid is extracellular fluid (ECF)?
20%
ECF includes fluid outside cells, comprising intravascular, interstitial, and transcellular fluids.
Fluid % Intravascular and Interstitial
Intravascular (Plasma) 5%
Interstitial (surrounds tissues/cells) 14%
What is the best indicator of fluid loss or gain?
Change in daily weight
-Weight-in at the same time each day wearing the same clothes
1 L of water is equal to 1 kg of body weight.
1 L of water weighs 2.2 lbs
Define electrolytes.
Substances whose molecules dissociate into ions when placed in water
Electrolytes are crucial for various physiological functions.
What is the prevalent cation/anion in intracellular fluid (ICF)?
K+ (Potassium)
(PO4)3-
K+ is essential for cell function and electrical activity.
What is the prevalent cation/anion in extracellular fluid (ECF)?
Na+ (Sodium)
Anion- Cl-
Na+ is vital for maintaining fluid balance and nerve function.
What is diffusion?
Movement of molecules across a permeable membrane from high to low concentration
Diffusion is a passive process that does not require energy.
Facilitated Diffusion
Uses carrier to help move molecules
Protein channels- no energy required
What is osmosis?
Movement of water ‘down’ concentration gradient
-From a region of low solute concentrarion to one of high solute concentration
-across a semipermeable membrane
Osmosis occurs across a semipermeable membrane and does not require outside energy.
Active Transport
Process in which molecules move against concentration gradient
External energy is needed for this process
AKA sodium/potassium pump
What does osmotic pressure measure?
Amount pressure/force required to stop osmotic flow of water
Calculate plasma osmolality using the formula: Plasma Osmolality = (2 × Na) + (BUN / 2.8) + (glucose / 18). What is the normal range?
Normal plasma osmolality is between 280 and 295 mOsm/kg
Values outside this range indicate- water deficit and water exess
What does hypotonic mean?
Solutes less concentrated than in cells
Hypotonic solutions can cause cell swelling.
What does hypertonic mean?
Solutes more concentrated than in cells
Hypertonic solutions can lead to cell shrinkage.
What is hydrostatic pressure?
Force of fluid in a compartment
the pressure that exists within a fluid that is not moving. It’s caused by the weight of the fluid, or the force of gravity acting on the fluid.
(static)
Hydrostatic pressure is generated by the heart’s contraction.
Oncotic Pressure
Colloid osmotic pressure
Osmotic pressure caused by plasma proteins
What causes edema?
Shifts of plasma to interstitial fluid, elevation of venous hydrostatic pressure, decrease in plasma oncotic pressure, elevation of interstitial oncotic pressure
Edema is an abnormal accumulation of fluid in interstitial spaces.
What is fluid spacing?
First spacing: Normal distribution; Second spacing: Abnormal accumulation of interstitial fluid (edema); Third spacing: Fluid is trapped where it is difficult or impossible for it to move back
Understanding fluid spacing is critical in assessing fluid imbalances.
What is the primary function of the kidneys in fluid balance?
Regulating fluid and electrolyte balance by adjusting urine volume and selectively reabsorbing water and electrolytes
The kidneys are essential for maintaining homeostasis.
Adrenal cortical regulation
Releases hormones to regulate water and electrolytes (cortisol/aldosterone)
Gerontologic considerations
-Structural changes in kidneys decrease ability to conserve water
-Hormonal changes include a decrease in renin and aldosterone and increase in ADH and ANP
-Subcutaneous tissue loss leads to increased moisture lost
Developmental considerations: Older adults
Increased risk for dehydration due to:
Less total body water
Decreased thirst mechanism
Decreased mobility difficulty obtaining fluids
Medications that increase fluid excretion