Fluid and Hemodynamics 2 Flashcards
What is a thrombus?
Platelets + Fibrin + cellular elements
Where does a thrombus attach?
Vessel wall
What is a clot?
RBCs + coagulation factors
Where is a clot?
Not attached to vessel wall
What does a “Currant-jelly clot” look like?
Dark to red black, smooth and shiny surface, rubbery, uniform, molded to shape of vessel, not attached, and has RBCs
What does a “Chicken-fat clot” look like?
Smooth and shiny surface, rubbery, uniform, molded to shape of vessel, yellow, results from settling and separate of RBCs and plasma, supernatant, no/few RBCs
Appearance of thrombus?
Heterogeneous
What are lines of Zahn?
Alternating layers of platelets/fibrin (pale) and RBCs (dark) in arterial thrombi
Cause of thrombus? Cause of Clot?
Endothelial injury
Stagnant blood
Consistency of thrombus? of Clot?
Dry
Moist
Surface of thrombus? of Clot?
Granular, rough
Smooth, glistening
What does arterial thrombus look like?
Pale, gray-tan, friable, concentric layers, attached to vessel wall
What does venous thrombus look like?
Red, friable, attached to vessel wall, commonly confused with clot, can be occlusive
How can thrombosis alter normal blood flow? (2)
Turbulence
Stasis
Virchow’s triad is made up of what?
Hypercoagulability
Hemodynamic changes
Endothelial injury
Turbulence is caused by what?
Arterial and cardiac thrombi