Fluid & Electrolytes Flashcards
(115 cards)
Define Electrolyte
A solute that develops an electrical charge (sodium and potassium).
Intracellular fluid
Fluid contained within the cells. 40% of body weight and is responsible for cell function and metabolism. ~28L in adult
Extracellular fluid
Fluid outside the cells. 20% body weight, carries water, oxygen, electrolytes, nutrients to cells and removes waste products from cellular ,metabolism. ~14L in adult
Major electrolytes in ICF; cations and anion
Cations: Potassium, magnesium
Anion: phosphate
Main electrolytes in ECF; cations and anion
Cations: sodium, chloride
Anion: bicarbonate
Define interstitial fluid
ECF located in the spaces between the cells. Excess fluid here is called edema. Second spacing
Define intravascular fluid
ECF located within the blood vessels. It is the plasma located in the blood. Transports blood cells
Define transcellular fluid
ECF that includes specialized fluids that are contained in body spaces ( cerebrospinal, pleural, peritoneal, and synovial fluids) and digestive juices. ~1L
Fluid movement into a compartment is known as third spacing (Ascities).
Define osmolality (tonicity)
The concentration of solutes creating pressure in body fluid.
Isotonic solution
Of the same osmolality of blood ; no osmosis will occur
Hypotonic solution
Of lower osmolality than blood ; water will move into cells by osmosis from vascular system
Hypertonic solution
Contains a higher concentration of solutes than blood ; water moves by osmosis out of cells into ECF
Define osmosis
The movement of water (passive) from a lower solute concentration to a higher solute concentration to achieve dilution of higher solute concentration to reach equilibrium
Define diffusion
Movement (passive) of molecules of a solute from a higher concentration to a lower concentration to reach equilibrium
Factors affecting rate of diffusion
Size of molecule, concentration of solution, and temperature of solution.
What are crystalliods
Solutes that readily dissolve ( electrolytes)
What are colloids
Larger molecules that do not dissolve readily ( proteins)
Define filtration
The movement of both water and smaller solutes from an area of high pressure to area of low pressure
Define hydrostatic pressure
The force created by fluid within a closed system ; responsible for normal circulation of blood
High pressure (arteries) to low pressure (capillaries and veins)
Define osmotic pressure
The power of a solution to draw water.
A highly concentrated solution draws water and has a high osmotic pressure.
Filtration pressure
When hydrostatic pressure exceeds osmotic pressure fluid leaves the vessels.
Represents the net pressures that move fluid and solutes
Active transport
Occurs when molecules move across cell membranes against the concentration gradient with the use of ATP (from an area of low concentration to an area of high concentration)
Ex: sodium-potassium pump
Define Solute
Solid substance that dissolves in body fluids
Factors that increase plasma osmolality
excessive fluid loss, excessive sodium intake, and decreased fluid intake.