FLUID LOSS

Question 1

What causes diarrhoea ?

Answer 1

-Failure of water absoprtion
-Increased water secretion
Or both

Question 2

Causes of decreased absorption?

Answer 2

• Increased number of osmotic particles (osmotic diarrhoea)
• Increased rate of flow of intestinal contents (deranged motility diarrhoea)
• Abnormal increase in secretions of GIT (secretory diarrhoea)

Question 3

What is osmotic diarrhoea?

Answer 3

Decreased absorption of electrolytes and nutrients
(disacccharidase deficiency)

Question 4

What is secretory diarrhoea?

Answer 4

Ach,substance P, 5-HT and neurotensin act via increase

Increase in Ca+ increases arey of intestinal secretion

Question 5

Causes of bloody diarrhoea?

Answer 5

• Chronic disease
• Ulcerative colitis
• Neoplasm

Question 6

Major consequences of sever diarrhoea?

Answer 6

• Excessive loss of water, nutrients, Na+, K+ and HCO3-
• Low blood volume
• Metabolic acidosis (due to loss of HCO3-)

Question 7

How does the body respond to water loss?

Answer 7

• Cardiovascular adaptation
• Renal adaptation

(behavioural and this stimulates water intake when possible to do so)