FMPR 420b Flashcards
(33 cards)
Statin drug interactions
macrolides (erythromycin, clarithromycin) inhibit CYP34A and therefore increase statin concentration , increased likelihood of S/E
Antibiotics + warfarin: does the INR increase or decrease?
increase- risk of bleeding
What types of drugs can affect the QT interval?
antiarrhythmics, antidepressants, antipsychotics, anti-infective
“mitte” =
“sig”=
mitte= quantity/duration of therapy Sig= specific instructions on how to take
keloids more likely when you do biopsies where?
upper chest, deltoid
waist circumference targets
white: W< 88, M<80
diabetes diagnosis thresholds
FPG >7.0 mM
A1C> 6.5%
75 g OGTT or random PG >11.1 mM
gliclazide and glyburide are….
sulfonylureas (insulin secretagogues)
metformin is…
a biguanide (insulin sensitizer)
humalog is….
lantus is…
humalog is rapid acting
lantus is extended release..
BMI cut-offs
<18.5 underweight
18.5-24.9 normal
25-29.9 overweight
30-35 obese
just remember there is a difference between neuroglycopenic and neurogenic symptoms of hypoglycemia. Which comes first?
Neurogenic
What are the components of the metabolic syndrome?
Depends on whether it is WHO criteri or NCEP
glucose BP Trigs HDL Abdominal obesity (WC or hip:waist ratio) ACR (part of WHO)
When to increase DM screening frequency?
age HTN Hx of GDM, or macorsomic infant ethnicity (first nations, indian, asian, african) >abdo circumference dyslipidemia end organ damage some meds some diseases (e.g. PCOS, psych, HIV, OSA...
Maybe review migraine cirteria… they can last for?
2 of: unilateral throbbing worse on exertion moderate to severe intensity
1 of:
photophobia +/- phonophobia
nausea +/- vomiting
Can last for 4-72 hrs
Triptans are contraindicated in…
any evidence of coronary artery disease. Use ergotamines instead?
What is MIDAS
migraine disability assessment tool
What are methods of emergency contraception and when can they be used?
- Plan B (levonogestrel 0.75 mg x 1 q12h or a single dose of 1.5 mg)
- Yuzpe (100 mcg of EE + 500 mcg of levonogestrel x 2)
- Copper IUD
hormonal methods are effective for 5 days post intercourse, IUD is effective for 7 post-intercourse
When are hormonal contraceptives effective after initiation of therapy?
7 days (pill, patch, ring, IUS****) OR right away if initiated on the first day of bleeding or Sunday start that falls in first 5 days
Contraindications for OCP
pregnancy risk of thrombosis (previous DVT, FHx(?), known valvular disease) smoker >35 y.o (>15 cig/day) estrogen dependent cancer sever liver disease migraine with aura
3 ways to start OCP
- “first day start”: on 1st day of menses
- “Sunday start”: on 1st sunday following onset of menses…don’t need back up if within 1st five days of menses
- “quick start”: any day of the cycle- use back up for 7 days
NYHA classification
1: no symptoms (but cardiac disease is known)
2: symptoms on exertion
3: symptoms with ordinary activity
4: symptoms at rest
What is the PPS for (palliative performance scale)?
to assess functional capacity….
When PPS changes from the stable level of function phase (PPS 100 ->70) to the transition level of function phase (PPS 60 -> 40) the patient should be referred to the community palliative care program
The difference between the Brief Pain Inventory and the Edmonton Symptom Assessment System (ESAS) is?
the Brief Pain Inventory inquires about how pain interferes with daily activities
