Food2150 set 1 Flashcards
(51 cards)
What is Classical Nutrition?
(~1800s-1970s)
- Relationship between food and health
- Prevent nutritional deficiency (Macro &
Micronutrients)
What is optimal nutrition?
1940s to 1990s
- Discovery of nutrients that prevent disease
- ‘right’ nutritional component was identified to prevent a disease
What is molecular nutrition?
> 1990s
- Incorporates functional foods & nutraceuticals to personalize nutrition based on genetics
- specific molecules maintain wellness, i.e. prevent or prolong onset of a
disease versus control a disease as in optimal
nutrition.
- ~ 75% of our illnesses are diet related - how
do we find and eat the ‘right’ things?
- nutrigenomics: personalized nutrition according to genetic make-up
What was the 1st Agricultural Revolution?
- Neolithic Revolution
- 11000 - 12000 years ago
- introduced farming
- Stock breading, no longer nomadic, stone milling
What was the 2nd Agricultural Revolution?
- British Agricultural Revolution
- 1600’s to 1800’s
- basic farming
- crop rotation, clover to add nitrogen (fertilizer), deep plowing
What was the 3rd Agricultural Revolution?
- Green Revolution
- 1950-today
- scientific farming
- high yielding seeds, chemical fertilizers, factory farms, machinery
What did the Industrial Revolution do for the food industry?
- printing press, automobile, electricity Machinery to preserve & formulate ultra-processed foods from ingredients derived from whole foods
What is the NOVA classification of Food?
Group 1 -Unprocessed or minimally processed
Group 2- Processed culinary ingredients
Group 3 –Processed foods
Group 4- Ultra-processed foods (UPFs)
What causes metabolic syndrome?
Diets high in UPF
What are side effects of Metabolic syndrome?
1) increased blood pressure,
2) high blood sugar,
3) excess body fat around the waist
4) abnormal cholesterol
5) High triglyceride levels
What are Food swamps?
- Places devoid of grocery stores, farmers markets
- High in fast food, convenience stores, UPF
When did the western diet start?
- post industrial revolution
- 10 000 years ago, intro of agriculture
- increase in yield and modified ingredients
- intro of animal husbandry (increase in fat consumption)
What are elements that are in the body?
- 96% is CHNO
- 1.5% Ca
- 1% P
- trace amounts of K, Na, Cl, S, Mg
- ultra-trace (0.15%): Mn, Fe, Co, Cu, Z, Se, Mb, I (toxic at upper limits)
What % of the body is made of water?
- 60% adult
- up to 80% of birth weight
- daily water intake: 1.5-2.5 L (water obtained from food -40% and beverages -60%)
- 30% extracellular (blood, lymph, digesta fluids, interstitial fluid)
- 70% intracellular (muscle, adipose cells)
How is water lost from the body?
- urine (~50%)
- stool (10%)
- insensible losses (40%) (sweating)
- consumed during chemical reactions
What does water do for the body?
- maintains blood volume, osmolarity
- removes body toxins
- transports nutrients via circulatory and lymphatic systems
- essential as reactant
- solvent to transport nutrients
- consumed during hydrolytic enzymatic reactions
What is blood osmolality?
- tightly regulated physiological (homeostatic) parameters
- normal values: 275 to 295 mOsm/kg (mmol/kg)
What is OsM?
- defined by osmoles of solute per liter, an osmole is one mole of dissolved and dissociated substance in water
- 1 mole of monosaccharide corresponds to 1 OsM, 1 mole of NaCl is 2 OsM as it dissociates into Na+ and Cl–
- colligative property: does not depend on molecular size or charge, is only affected by the concentration of dissolved solutes.
What are the macronutrients?
carbs, lipids, proteins
Describe carbohydrates
- Contain hydrogen (2X) carbon and oxygen (CH2O)
45–65% daily calorie intake (ATP & NADPH) - simple sugars, oligosaccharides, polysaccharides
- digestible (glycemic: dextrin, starch, glycogen) and non-digestible (non-glycemic: fiber)
What is the glycemic index?
- based on carbs and their types
- more refined foods: easier to digest, for sugar it is higher than long-chain carbs
- blood glucose-raising potential of food compared to either white bread or glucose
Describe lipids
- 20-35% calorie intake
- used for energy storage, hormone production, and cell
membrane integrity and absorption of fat-soluble
micronutrients - Triglycerides
- Glycerol esterified to 3 fatty acids
- Saturated (no double bonds) - Monosaturated (1 double bond) (cis and trans isomers)
- Polyunsaturated (>1 double bond) (cis and trans isomers)
- fat shuttles as chylomicrons
What are chylomicrons?
- small intestine to the liver, and as it transits, the extracellular
enzyme lipoprotein lipase (LPL) found on the vascular endothelial surfaces, hydrolyzes circulating triglyceride-rich lipoproteins,
including chylomicrons and very low-density lipoproteins (VLDL) - After reuptake by the liver, cholesterol synthesis occurs and shuttles it through the body to tissues using the reverse
transport pathway as high-density lipoprotein (HDL) coated in ApoA, ApoC, and ApoE.
HDL transits through circulation, picking up excess cholesterol from tissues while delivering it to those needing
cholesterol or other lipoproteins - endogenous pathway synthesizes VLDL, coated in Ap0B100
, ApoC and ApoE,
while circulating fatty acids are cleaved off by LPL, converting VLDL into low-density lipoprotein (LDL).
VLDL leaves the liver containing 60% triglyceride, 18% phospholipid, 12% cholesterol, and 10% protein
LDL returns with 10% triglyceride, 22% phospholipid, 45% cholesterol, and 23% protein.
Describe proteins
- made from 20 amino acids
- 10-30% dairy calorie intake
- -100-1000 of amino acids
Peptide < 10-30 (protein fragments) - no advantages of fast or slow digesting proteins, just whether it has AA
- essential AA: (H, I, L, K, M, F, T, W, V)